Search

This volume contains the contributions from the speakers at the NATO Advanced Research Workshop on'Structure of the Photosynthetic Bacterial Reaction Center X-ray Crystallography and Optical Spectroscopy with Polarized Light'which was held at the'Maison d'Hotes'of the Centre d'Etudes Nucleaires de Cadarache in the South of France, 20-25 September, 1987. This meeting continued in the spirit of a previous workshop which took place in Feldafing (FRG), March 1985. Photosynthetic reaction centers are intrinsic membrane proteins which, by performing a photoinduced transmembrane charge separation, are responsible for the conversion and storage of solar energy. Since the pioneering work of Reed and Clayton (1968) on the isolation of the reaction center from photosynthetic bacteria, optical spectroscopy with polarized light has been one of the main tools used to investigate the geometrical arrangement of the various chromophores in these systems. The recent elucidation by X-ray crystallography of the structure of several bacterial reaction centers, a breakthrough initiated by Michel and Deisenhofer, has provided us with the atomic coordinates of the pigments and some details about their interactions with neighboring aminoacid residues. This essential step has given a large impetus both to experimentalists and to theoreticians who are now attempting to relate the X-ray structural model to the optical properties of the reaction center and ultimately to its primary biological function.

The NATO Advanced Research Workshop entitled'The Photosynthetic Bacterial Reaction Center: Structure, Spectroscopy, and Dynamics'was held May 10-15, 1992, in the Maison d'H6tes of the Centre d'Etudes Nuc1eaires de Cadarache near Aix-en-Provence in the south of France. This workshop is the most recent of a string of meetings which started in Feldafing (Germany) in March 1985, soon after the three-dimensional structure of the bacterial reaction center had been elucidated by X-ray crystallography. This was followed, in September 1987, by a workshop in Cadarache and, in March 1990, by a second meeting in Feldafing. Although one of the most important processes on Earth, photosynthesis is still poorly understood. Stimulated by the breakthrough of solving the bacterial reaction center structure at atomic resolution, the field of relating this structure to the function of the reaction center, i. e. the remarkably efficient conversion and storage of solar energy, has been developing vigorously. Once the general organization of the cofactors and some details of the protein-cofactor interactions were known, it became possible to combine a variety of spectroscopic techniques with the powerful tool of site-directed mutagenesis in order to address increasingly incisive questions about the specific role of some amino acid residues in the electron transfer process. Still another promising tool is being developed, namely the exchange of a number of the native bacteriochlorophyll and bacteriopheophytin cofactors by chemically modified pigments.

Results of this third Feldafing Meeting can be considered as the harvest of novel techniques in spectroscopy, biochemistry and molecular biology to the bacterial photosynthetic reaction center. New information pertains to the crystallographic and electronic structure as well as to the dynamics of primary events and the role of the protein. The answer to one long-standing problem, the mechanism of primary charge separation, converges towards a sequential scheme, supported by femtosecond spectroscopy on reaction centers with selectively modified energetics.

Light Transducing Membranes: Structure, Function, and Evolution covers the proceedings of a joint United States-Australia conference held in Honolulu, Hawaii on December 1977. Organized into four parts encompassing 19 chapters, the book focuses on structural, functional, and evolutionary aspects of light energy transduction by membranes. The first part of the book explores the problems of how membrane-related biomolecules could have evolved prior to the origin of life, how amphiphiles might have become organized in lipid bilayer structures, and what mechanisms may have been available for light energy transduction. The mechanisms by which ions, lipids, and proteins interact in membrane systems are described in the next part of the book. Some chapters in the third part of the book cover the analysis of several bacterial membranes as reconstituted, light transducing systems, providing a new tool for investigating basic mechanisms. Relevant aspects of mitochondrial energy transduction are also covered. Finally, the last part presents mechanism analysis by which intact bacteria and chloroplasts interact with light energy, which represent the end product of several billion of years of evolution. Biological evolutionists, biologists, researchers, teachers, and students who are interested in various aspects of light transducing membranes will greatly benefit from this book.

The world needs clean and renewable energy and hydrogen represents an almost ideal resource. Hydrogen is the simplest and most abundant molecule in the universe, yet one that is a challenge to produce from renewable resources. Biohydrogen, or hydrogen produced from renewable resources such as water or organic wastes by biological means, is a goal worthy of increased global attention and resources. The purpose of BioHydrogen'97 was to bring together leaders in the biological p- duction of hydrogen from the United States, Japan, Europe, and elsewhere to exchange scientific and technical information and catalyze further cooperative programs. Parti- pants came from at least different countries representing academia, industry, and g- ernment. Especially important participants were young research scientists and engineers: the next generation of contributors. The conference consisted of plenary presentations, topical sessions, posters, and mini-workshop discussions on key areas of biohydrogen. It was designed to maximize - formation exchange, personal interaction among participants, and formulate new inter- tional initiatives. BioHydrogen'97 was an outgrowth of an international workshop convened by the Research Institute of Innovative Technology for the Earth (RITE) and was held in Tokyo, Japan, November 24-25, 1994. The RITE workshop was highly successful but largely l- ited to traditional biochemical and biological studies and not engineering research topics.