44 results on '"Phan Duc, T."'
Search Results
2. A modular microfluidic system based on a multilayered configuration to generate large-scale perfusable microvascular networks
- Author
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Yue, Tao, Zhao, Da, Phan, Duc T. T., Wang, Xiaolin, Park, Joshua Jonghyun, Biviji, Zayn, Hughes, Christopher C. W., and Lee, Abraham P.
- Published
- 2021
- Full Text
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3. Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis
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Hultgren, Nan W., Fang, Jennifer S., Ziegler, Mary E., Ramirez, Ricardo N., Phan, Duc T. T., Hatch, Michaela M. S., Welch-Reardon, Katrina M., Paniagua, Antonio E., Kim, Lin S., Shon, Nathan N., Williams, David S., Mortazavi, Ali, and Hughes, Christopher C. W.
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- 2020
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4. Bridging the gap between tumor-on-chip and clinics: a systematic review of 15 years of studies
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Bouquerel, Charlotte, primary, Dubrova, Anastasiia, additional, Hofer, Isabella, additional, Phan, Duc T. T., additional, Bernheim, Moencopi, additional, Ladaigue, Ségolène, additional, Cavaniol, Charles, additional, Maddalo, Danilo, additional, Cabel, Luc, additional, Mechta-Grigoriou, Fatima, additional, Wilhelm, Claire, additional, Zalcman, Gérard, additional, Parrini, Maria Carla, additional, and Descroix, Stéphanie, additional
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- 2023
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5. 3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels
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Wang, Xiaolin, primary, Phan, Duc T. T., additional, George, Steven C., additional, Hughes, Christopher C. W., additional, and Lee, Abraham P., additional
- Published
- 2017
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6. MATISSE, the VLTI mid-infrared imaging spectro-interferometer
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Lopez, B., primary, Lagarde, S., additional, Petrov, R. G., additional, Jaffe, W., additional, Antonelli, P., additional, Allouche, F., additional, Berio, P., additional, Matter, A., additional, Meilland, A., additional, Millour, F., additional, Robbe-Dubois, S., additional, Henning, Th., additional, Weigelt, G., additional, Glindemann, A., additional, Agocs, T., additional, Bailet, Ch., additional, Beckmann, U., additional, Bettonvil, F., additional, van Boekel, R., additional, Bourget, P., additional, Bresson, Y., additional, Bristow, P., additional, Cruzalèbes, P., additional, Eldswijk, E., additional, Fanteï Caujolle, Y., additional, González Herrera, J. C., additional, Graser, U., additional, Guajardo, P., additional, Heininger, M., additional, Hofmann, K.-H., additional, Kroes, G., additional, Laun, W., additional, Lehmitz, M., additional, Leinert, C., additional, Meisenheimer, K., additional, Morel, S., additional, Neumann, U., additional, Paladini, C., additional, Percheron, I., additional, Riquelme, M., additional, Schoeller, M., additional, Stee, Ph., additional, Venema, L., additional, Woillez, J., additional, Zins, G., additional, Ábrahám, P., additional, Abadie, S., additional, Abuter, R., additional, Accardo, M., additional, Adler, T., additional, Alonso, J., additional, Augereau, J.-C., additional, Böhm, A., additional, Bazin, G., additional, Beltran, J., additional, Bensberg, A., additional, Boland, W., additional, Brast, R., additional, Burtscher, L., additional, Castillo, R., additional, Chelli, A., additional, Cid, C., additional, Clausse, J.-M., additional, Connot, C., additional, Conzelmann, R. D., additional, Danchi, W.-C., additional, Delbo, M., additional, Drevon, J., additional, Dominik, C., additional, van Duin, A., additional, Ebert, M., additional, Eisenhauer, F., additional, Flament, S., additional, Frahm, R., additional, Gámez Rosas, V., additional, Gabasch, A., additional, Gallenne, A., additional, Garces, E., additional, Girard, P., additional, Glazenborg, A., additional, Gonté, F. Y. J., additional, Guitton, F., additional, de Haan, M., additional, Hanenburg, H., additional, Haubois, X., additional, Hocdé, V., additional, Hogerheijde, M., additional, ter Horst, R., additional, Hron, J., additional, Hummel, C. A., additional, Hubin, N., additional, Huerta, R., additional, Idserda, J., additional, Isbell, J. W., additional, Ives, D., additional, Jakob, G., additional, Jaskó, A., additional, Jochum, L., additional, Klarmann, L., additional, Klein, R., additional, Kragt, J., additional, Kuindersma, S., additional, Kokoulina, E., additional, Labadie, L., additional, Lacour, S., additional, Leftley, J., additional, Le Poole, R., additional, Lizon, J.-L., additional, Lopez, M., additional, Lykou, F., additional, Mérand, A., additional, Marcotto, A., additional, Mauclert, N., additional, Maurer, T., additional, Mehrgan, L. H., additional, Meisner, J., additional, Meixner, K., additional, Mellein, M., additional, Menut, J. L., additional, Mohr, L., additional, Mosoni, L., additional, Navarro, R., additional, Nußbaum, E., additional, Pallanca, L., additional, Pantin, E., additional, Pasquini, L., additional, Phan Duc, T., additional, Pott, J.-U., additional, Pozna, E., additional, Richichi, A., additional, Ridinger, A., additional, Rigal, F., additional, Rivinius, Th., additional, Roelfsema, R., additional, Rohloff, R.-R., additional, Rousseau, S., additional, Salabert, D., additional, Schertl, D., additional, Schuhler, N., additional, Schuil, M., additional, Shabun, K., additional, Soulain, A., additional, Stephan, C., additional, Toledo, P., additional, Tristram, K., additional, Tromp, N., additional, Vakili, F., additional, Varga, J., additional, Vinther, J., additional, Waters, L. B. F. M., additional, Wittkowski, M., additional, Wolf, S., additional, Wrhel, F., additional, and Yoffe, G., additional
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- 2022
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7. An Overview of the Mid-Infrared Spectro-Interferometer MATISSE: Science, Concept, and Current Status
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Matter, A, Lopez, B, Antonelli, P, Lehmitz, M, Bettonvil, F, Beckmann, U, Lagarde, S, Jaffe, W, Petrov, R. G, Berio, P, Millour, F, Robbe-Dubois, S, Glindemann, A, Bristow, P, Schoeller, M, Lanz, T, Henning, T, Weigelt, G, Heininger, M, Morel, S, Cruzalebes, P, Meisenheimer, K, Hofferbert, R, Wolf, S, Bresson, Y, Agocs, T, Allouche, F, Augereau, J.-C, Avila, G, Bailet, C, Behrend, J, Van Belle, G, Berger, J.-P, Van Boekel, R, Bourget, P, Brast, R, Clausse, J.-M, Connot, C, Conzelmann, R, Csepany, G, Danchi, W. C, Delbo, M, Dominik, C, Van Duin, A, Elswijk, E, Fantei, Y, Finger, G, Gabasch, A, Gonte, F, Graser, U, Guitton, F, Guniat, S, De Haan, M, Haguenauer, P, Hanenburg, H, Hofmann, K.-H, Hogerheijde, M, Ter Horst, R, Hron, J, Hummel, C, Isderda, J, Ives, D, Jakob, G, Jasko, A, Jolley, P, Kiraly, S, Kragt, J, Kroener, T, Kroes, G, Kuindersma, S, Labadie, L, Laun, W, Leinert, C, Lizon, J.-L, Lucuix, C, Marcotto, A, Martinache, F, Martinot-Lagarde, G, Mauclert, N, Mehrgan, L, Meilland, A, Mellein, M, Menardi, S, Merand, A, Neumann, U, Nussbaum, E, Ottogalli, S, Palsa, R, Panduro, J, Pantin, E, Percheron, I, Phan Duc, T, Pott, J.-U, Pozna, E, Roelfsema, R, Rupprecht, G, Schertl, D, Schmidt, C, Schuil, M, Spang, A, Stegmeier, J, Tromp, N, Vakili, F, Vannier, M, Wagner, K, Venema, L, and Woillez, J
- Subjects
Astrophysics - Abstract
MATISSE is the second-generation mid-infrared spectrograph and imager for the Very Large Telescope Interferometer (VLTI) at Paranal. This new interferometric instrument will allow significant advances by opening new avenues in various fundamental research fields: studying the planet-forming region of disks around young stellar objects, understanding the surface structures and mass loss phenomena affecting evolved stars, and probing the environments of black holes in active galactic nuclei. As a first breakthrough, MATISSE will enlarge the spectral domain of current optical interferometers by offering the L and M bands in addition to the N band. This will open a wide wavelength domain, ranging from 2.8 to 13 microns, exploring angular scales as small as 3 mas (L band) 10 mas (N band). As a second breakthrough, MATISSE will allow mid-infrared imaging - closure-phase aperture-synthesis imaging - with up to four Unit Telescopes (UT) or Auxiliary Telescopes (AT) of the VLTI. Moreover, MATISSE will offer a spectral resolution range from R approx. 30 to R approx. 5000. Here, we present one of the main science objectives, the study of protoplanetary disks, that has driven the instrument design and motivated several VLTI upgrades (GRA4MAT and NAOMI). We introduce the physical concept of MATISSE including a description of the signal on the detectors and an evaluation of the expected performances. We also discuss the current status of the MATISSE instrument, which is entering its testing phase, and the foreseen schedule for the next two years that will lead to the first light at Paranal.
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- 2016
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- View/download PDF
8. Mid-infrared circumstellar emission of the long-period Cepheid ℓ Carinae resolved with VLTI/MATISSE
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Hocdé, V., primary, Nardetto, N., additional, Matter, A., additional, Lagadec, E., additional, Mérand, A., additional, Cruzalèbes, P., additional, Meilland, A., additional, Millour, F., additional, Lopez, B., additional, Berio, P., additional, Weigelt, G., additional, Petrov, R., additional, Isbell, J. W., additional, Jaffe, W., additional, Kervella, P., additional, Glindemann, A., additional, Schöller, M., additional, Allouche, F., additional, Gallenne, A., additional, Domiciano de Souza, A., additional, Niccolini, G., additional, Kokoulina, E., additional, Varga, J., additional, Lagarde, S., additional, Augereau, J.-C., additional, van Boekel, R., additional, Bristow, P., additional, Henning, Th., additional, Hofmann, K.-H., additional, Zins, G., additional, Danchi, W.-C., additional, Delbo, M., additional, Dominik, C., additional, Gámez Rosas, V., additional, Klarmann, L., additional, Hron, J., additional, Hogerheijde, M. R., additional, Meisenheimer, K., additional, Pantin, E., additional, Paladini, C., additional, Robbe-Dubois, S., additional, Schertl, D., additional, Stee, P., additional, Waters, R., additional, Lehmitz, M., additional, Bettonvil, F., additional, Heininger, M., additional, Woillez, J., additional, Wolf, S., additional, Yoffe, G., additional, Szabados, L., additional, Chiavassa, A., additional, Borgniet, S., additional, Breuval, L., additional, Javanmardi, B., additional, Ábrahám, P., additional, Abadie, S., additional, Abuter, R., additional, Accardo, M., additional, Adler, T., additional, Agócs, T., additional, Alonso, J., additional, Antonelli, P., additional, Böhm, A., additional, Bailet, C., additional, Bazin, G., additional, Beckmann, U., additional, Beltran, J., additional, Boland, W., additional, Bourget, P., additional, Brast, R., additional, Bresson, Y., additional, Burtscher, L., additional, Buter, R., additional, Castillo, R., additional, Chelli, A., additional, Cid, C., additional, Clausse, J.-M., additional, Connot, C., additional, Conzelmann, R. D., additional, De Haan, M., additional, Ebert, M., additional, Elswijk, E., additional, Fantei, Y., additional, Frahm, R., additional, Gabasch, A., additional, Garces, E., additional, Girard, P., additional, Glazenborg, A., additional, Gonté, F. Y. J., additional, González Herrera, J. C., additional, Graser, U., additional, Guajardo, P., additional, Guitton, F., additional, Hanenburg, H., additional, Haubois, X., additional, Hubin, N., additional, Huerta, R., additional, Idserda, J., additional, Ives, D., additional, Jakob, G., additional, Jaskó, A., additional, Jochum, L., additional, Klein, R., additional, Kragt, J., additional, Kroes, G., additional, Kuindersma, S., additional, Labadie, L., additional, Laun, W., additional, Le Poole, R., additional, Leinert, C., additional, Lizon, J.-L., additional, Lopez, M., additional, Marcotto, A., additional, Mauclert, N., additional, Maurer, T., additional, Mehrgan, L. H., additional, Meisner, J., additional, Meixner, K., additional, Mellein, M., additional, Mohr, L., additional, Morel, S., additional, Mosoni, L., additional, Navarro, R., additional, Neumann, U., additional, Nußbaum, E., additional, Pallanca, L., additional, Pasquini, L., additional, Percheron, I., additional, Phan Duc, T., additional, Pott, J.-U., additional, Pozna, E., additional, Ridinger, A., additional, Rigal, F., additional, Riquelme, M., additional, Rivinius, Th., additional, Roelfsema, R., additional, Rohloff, R.-R., additional, Rousseau, S., additional, Schuhler, N., additional, Schuil, M., additional, Shabun, K., additional, Soulain, A., additional, Stephan, C., additional, ter Horst, R., additional, Tromp, N., additional, Vakili, F., additional, van Duin, A., additional, Venema, L. B., additional, Vinther, J., additional, Wittkowski, M., additional, and Wrhel, F., additional
- Published
- 2021
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9. The VLTI – A Status Report
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Glindemann, A., Algomedo, J., Amestica, R., Ballester, P., Bauvir, B., Bugueño, E., Correia, S., Delgado, F., Delplancke, F., Derie, F., Duhoux, Ph., di Folco, E., Gennai, A., Gilli, B., Giordano, P., Gitton, Ph., Guisard, S., Housen, N., Huxley, A., Kervella, P., Kiekebusch, M., Koehler, B., Lévêque, S., Longinotti, A., Ménardi, S., Morel, S., Paresce, F., Phan Duc, T., Richichi, A., Schöller, M., Tarenghi, M., Wallander, A., Wittkowski, M., and Wilhelm, R.
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- 2003
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10. Hunting Exoplanets with Single-Mode Optical Interferometry
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Abuter, R., Accardo, M., Adler, T., Amorim, A., Anugu, N., Ávila, G., Bauböck, M., Benisty, M., Berger, J.-P., Bestenlehner, J. M., Beust, H., Blind, N., Bonnefoy, M., BONNET, H., Bourget, P., Bouvier, J., Brandner, W., Brast, R., Buron, A., Burtscher, L., Cantalloube, F., Caratti O Garatti, A., Caselli, P., Cassaing, F., Chapron, F., Charnay, B., Choquet, E., Clénet, Y., Collin, C., Coudé Du Foresto, V., Davies, R., Deen, C., Delplancke-Ströbele, F., Dembet, R., Derie, F., de Wit, W.-J., Dexter, J., De Zeeuw, T., Dougados, C., Dubus, G., Duvert, G., Ebert, M., Eckart, A., Eisenhauer, F., Esselborn, M., Eupen, F., Fédou, P., Ferreira, M. C., Finger, G., Förster Schreiber, N. M., Gao, F., García Dabó, C. E., Garcia Lopez, R., Garcia, P. J. V., Gendron, É., Genzel, R., Gerhard, O., Gil, J. P., Gillessen, S., Gonté, F., Gordo, P., Gratadour, D., Greenbaum, A., Grellmann, R., Grözinger, U., Guajardo, P., Guieu, S., Habibi, M., Haguenauer, P., Hans, O., Haubois, X., Haug, M., Haußmann, F., Henning, T., Hippler, S., Hönig, S. F., Horrobin, M., Huber, A., Hubert, Z., Hubin, N., Hummel, C. A., Jakob, G., Janssen, A., Jimenez Rosales, A., Jochum, L., Jocou, L., Kammerer, J., Karl, M., Kaufer, A., Kellner, S., Kendrew, S., Kern, L., Kervella, P., Kiekebusch, M., Kishimoto, M., Klarmann, L., Klein, R., Köhler, R., Kok, Y., Kolb, J., Koutoulaki, M., Kulas, M., Labadie, L., Lacour, S., Lagrange, A.-M., Lapeyrère, V., Laun, W., Lazareff, B., Le Bouquin, J.-B., Léna, P., Lenzen, R., Lévêque, S., Lin, C.-C., Lippa, M., Lutz, D., Magnard, Y., Maire, A.-L., Mehrgan, L., Mérand, A., Millour, F., Mollière, P., Moulin, T., Müller, A., Müller, E., Müller, F., Netzer, H., Neumann, U., Nowak, M., Oberti, S., Ott, T., Pallanca, L., Panduro, J., Pasquini, L., Paumard, T., Percheron, I., Perraut, K., Perrin, G., Peterson, B. M., Petrucci, P.-O., Pflüger, A., Pfuhl, O., Phan Duc, T., Pineda, J. E., Plewa, P. m., Popovic, D., Pott, J.-U., Prieto, A., Pueyo, L., Rabien, S., Ramírez, A., Ramos, J. R., Rau, C., Ray, T., Riquelme, M., Rodríguez-Coira, G., Rohloff, R.-R., Rouan, D., Rousset, G., Sanchez-Bermudez, J., Schartmann, M., Scheithauer, S., Schöller, M., Schuhler, N., Segura-Cox, D., Shangguan, J., Shimizu, T. T., Spyromilio, J., Sternberg, A., Stock, M. R., Straub, O., Straubmeier, C., Sturm, E., Suárez Valles, M., Tacconi, L. J., Thi, W.-F., Tristram, K. R. W., Valenzuela, J. J., Van Boekel, R., Van Dishoeck, E. F., Vermot, P., Vincent, F., Von fellenberg, S., Waisberg, I., Wang, J. J., Wank, I., Weber, J., Weigelt, G., Widmann, F., Wieprecht, E., Wiest, M., Wiezorrek, E., Wittkowski, M., Woillez, J., Wolff, B., Yang, P., Yazici, S., Ziegler, D., Zins, G., and European Southern Observatory (ESO)
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[SDU]Sciences of the Universe [physics] ,Astrophysics::Instrumentation and Methods for Astrophysics ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics::Galaxy Astrophysics - Abstract
The GRAVITY instrument was primarily conceived for imaging and astrometry of the Galactic centre. However, its sensitivity and astrometric capabilities have also enabled interferometry to reach a new domain of astrophysics: exoplanetology. In March 2019, the GRAVITY collaboration published the first spectrum and astrometry of an exoplanet obtained by optical interferometry. In this article, we show how this observation is paving the way to even more exciting discoveries — finding new planets, and characterising their atmospheres., Published in The Messenger vol. 178, pp. 47-49, December 2019.
- Published
- 2019
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11. Images at the Highest Angular Resolution with GRAVITY: The Case of η Carinae
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Abuter, R., Accardo, M., Adler, T., Amorim, A., Anugu, N., Ávila, G., Bauböck, M., Benisty, M., Berger, J.-P., Bestenlehner, J. M., Beust, H., Blind, N., Bonnefoy, M., BONNET, H., Bourget, P., Bouvier, J., Brandner, W., Brast, R., Buron, A., Burtscher, L., Cantalloube, F., Caratti O Garatti, A., Caselli, P., Cassaing, F., Chapron, F., Charnay, B., Choquet, E., Clénet, Y., Collin, C., Coudé Du Foresto, V., Davies, R., Deen, C., Delplancke-Ströbele, F., Dembet, R., Derie, F., de Wit, W.-J., Dexter, J., De Zeeuw, T., Dougados, C., Dubus, G., Duvert, G., Ebert, M., Eckart, A., Eisenhauer, F., Esselborn, M., Eupen, F., Fédou, P., Ferreira, M. C., Finger, G., Förster Schreiber, N. M., Gao, F., García Dabó, C. E., Garcia Lopez, R., Garcia, P. J. V., Gendron, É., Genzel, R., Gerhard, O., Gil, J. P., Gillessen, S., Gonté, F., Gordo, P., Gratadour, D., Greenbaum, A., Grellmann, R., Grözinger, U., Guajardo, P., Guieu, S., Habibi, M., Haguenauer, P., Hans, O., Haubois, X., Haug, M., Haußmann, F., Henning, T., Hippler, S., Hönig, S. F., Horrobin, M., Huber, A., Hubert, Z., Hubin, N., Hummel, C. A., Jakob, G., Janssen, A., Jimenez Rosales, A., Jochum, L., Jocou, L., Kammerer, J., Karl, M., Kaufer, A., Kellner, S., Kendrew, S., Kern, L., Kervella, P., Kiekebusch, M., Kishimoto, M., Klarmann, L., Klein, R., Köhler, R., Kok, Y., Kolb, J., Koutoulaki, M., Kulas, M., Labadie, L., Lacour, S., Lagrange, A.-M., Lapeyrère, V., Laun, W., Lazareff, B., Le Bouquin, J.-B., Léna, P., Lenzen, R., Lévêque, S., Lin, C.-C., Lippa, M., Lutz, D., Magnard, Y., Maire, A.-L., Mehrgan, L., Mérand, A., Millour, F., Mollière, P., Moulin, T., Müller, A., Müller, E., Müller, F., Netzer, H., Neumann, U., Nowak, M., Oberti, S., Ott, T., Pallanca, L., Panduro, J., Pasquini, L., Paumard, T., Percheron, I., Perraut, K., Perrin, G., Peterson, B. M., Petrucci, P.-O., Pflüger, A., Pfuhl, O., Phan Duc, T., Pineda, J. E., Plewa, P. m., Popovic, D., Pott, J.-U., Prieto, A., Pueyo, L., Rabien, S., Ramírez, A., Ramos, J. R., Rau, C., Ray, T., Riquelme, M., Rodríguez-Coira, G., Rohloff, R.-R., Rouan, D., Rousset, G., Sanchez-Bermudez, J., Schartmann, M., Scheithauer, S., Schöller, M., Schuhler, N., Segura-Cox, D., Shangguan, J., Shimizu, T. T., Spyromilio, J., Sternberg, A., Stock, M. R., Straub, O., Straubmeier, C., Sturm, E., Suárez Valles, M., Tacconi, L. J., Thi, W.-F., Tristram, K. R. W., Valenzuela, J. J., Van Boekel, R., Van Dishoeck, E. F., Vermot, P., Vincent, F., Von fellenberg, S., Waisberg, I., Wang, J. J., Wank, I., Weber, J., Weigelt, G., Widmann, F., Wieprecht, E., Wiest, M., Wiezorrek, E., Wittkowski, M., Woillez, J., Wolff, B., Yang, P., Yazici, S., Ziegler, D., Zins, G., and European Southern Observatory (ESO)
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[SDU]Sciences of the Universe [physics] ,Astrophysics::High Energy Astrophysical Phenomena ,0103 physical sciences ,Astrophysics::Instrumentation and Methods for Astrophysics ,Astrophysics::Solar and Stellar Astrophysics ,010303 astronomy & astrophysics ,01 natural sciences - Abstract
The main goal of an interferometer is to probe the physics of astronomical objects at the highest possible angular resolution. The most intuitive way of doing this is by reconstructing images from the interferometric data. GRAVITY at the Very Large Telescope Interferometer (VLTI) has proven to be a fantastic instrument in this endeavour. In this article, we describe the reconstruction of the wind-wind collision cavity of the massive binary η Car with GRAVITY across two spectral lines: HeI and Brγ., Published in The Messenger vol. 178, pp. 31-33, December 2019.
- Published
- 2019
- Full Text
- View/download PDF
12. Effect of disk drive actuator unbalance on track following response to external vibration & shock
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Radwan, Hatem R., Phan, Duc T., and Cao, Kiet
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Disk drives -- Research ,Servomechanisms -- Research ,Actuators -- Research ,Business ,Electronics ,Electronics and electrical industries - Abstract
A two-disk, 2 1/2[inch] drive with a multirate observer-based controller is tested for operating vibration and shock, and the off-track performance of the servo system is measured. Measured data are compared to analytical predictions in each case. Actuator pivot unbalance is computed by comparing analysis results to measurement for 0.5G sine sweep excitation. Four shock excitations are considered from 20 G to 100G in amplitude, with 11 ms (milliseconds) and 2 ms durations. Predicted off-track displacements are converted to corresponding position error quadrature signals for comparison to measurement. Measured acceleration excitation is also used as input to the analysis. Predicted response compares favorably with measurement for operating vibration, as well as for shock excitations of 20G (11 ms), 50G (11 ms), and 25G (2 ms). For 100G (2 ms) shock, predicted response varies significantly from measurement. The paper also includes a discussion of the control algorithm typically used for head positioning in Seagate small disk drives today.
- Published
- 1996
13. Discrete-time LQG/LTR design and modeling of a disk drive actuator tracking servo system
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Weerasooriya, Siri and Phan, Duc T.
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Disk drives -- Design and construction ,Actuators -- Design and construction ,Tracking systems -- Design and construction ,Servomechanisms -- Design and construction ,Read/write heads -- Design and construction ,Business ,Computers ,Electronics ,Electronics and electrical industries - Abstract
This paper presents the discrete-time LQG/LTR design of a disk drive track following servo system. The servo compensator designed through linear-quadratic Gaussian control combined with loop transfer recovery (LQG/LTR) consists of a Kalman filter for state estimation and state feedback for control. The desired tracking servo performance is first formulated through a frequency shaped return ratio of the Kalman filter and subsequently recovered at the output of the plant/compensator loop through the automatic design of a discrete-time linear quadratic (LQ) regulator. Particular attention has been given to modeling the calculation time delay and bias force estimation. The excellent robustness and performance characteristics of a continuous time LQG/LTR design are theoretically unachievable due to the extremely low sampling rate and nonminimum phase plant characteristics. However, both time and frequency domain simulations show that reasonable stability margins and performance can still be recovered. This technique nearly eliminates all the trial and error typical of a conventional pole placement design of a similar system. The direct discrete-time design can handle extremely low sampling rates associated with embedded servo systems. The technique can also be used for designing multi-rate and multi-input servo systems.
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- 1995
14. Spatially Resolving the Quasar Broad Emission Line Region
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Abuter, R., Accardo, M., Adler, T., Amorim, A., Anugu, N., Ávila, G., Bauböck, M., Benisty, M., Berger, J.-P., Bestenlehner, J.M., Beust, H., Blind, N., Bonnefoy, M., Bonnet, H., Bourget, P., Bouvier, J., Brandner, W., Brast, R., Buron, A., Burtscher, L.H., Cantalloube, F., Caratti, O, Garatti, A., Caselli, P., Cassaing, F., Chapron, F., Charnay, B., Choquet, É., Clénet, Y., Collin, C., Coudé Du, Foresto, V., Davies, R., Deen, C., Delplancke-Ströbele, F., Dembet, R., Derie, F., De Wit, W.-J., Dexter, J., Zeeuw, T. de, Dougados, C., Dubus, G., Duvert, G., Ebert, M., Eckart, A., Eisenhauer, F., Esselborn, M., Eupen, F., Fédou, P., Ferreira, M.C., Finger, G., Förster Schreiber, N.M., Gao, F., García Dabó, C.E., Garcia Lopez, R., Garcia, P.J.V., Gendron, É., Genzel, R., Gerhard, O., Gil, J.P., Gillessen, S., Gonté, F., Gordo, P., Gratadour, D., Greenbaum, A., Grellmann, R., Grözinger, U., Guajardo, P., Guieu, S., Habibi, M., Haguenauer, P., Hans, O., Haubois, X., Haug, M., Haußmann, F., Henning, T., Hippler, S., Hönig, S.F., Horrobin, M., Huber, A., Hubert, Z., Hubin, N., Hummel, C.~A., Jakob, G., Janssen, A., Jimenez Rosales, A., Jochum, L., Jocou, L., Kammerer, J., Karl, M., Kaufer, A., Kellner, S., Kendrew, S., Kern, L., Kervella, P., Kiekebusch, M., Kishimoto, M., Klarmann, L., Klein, R., Köhler, R., Kok, Y., Kolb, J., Koutoulaki, M., Kulas, M., Labadie, L., Lacour, S., Lagrange, A.-M., Lapeyrère, V., Laun, W., Lazareff, B., Le Bouquin, J.-B., Léna, P., Lenzen, R., Lévêque, S., Lin, C.-C., Lippa, M., Lutz, D., Magnard, Y., Maire, A.-L., Mehrgan, L., Mérand, A., Millour, F., Mollière, P., Moulin, T., Müller, A., Müller, E., Müller, F., Netzer, H., Neumann, U., Nowak, M., Oberti, S., Ott, T., Pallanca, L., Panduro, J., Pasquini, L., Paumard, T., Percheron, I., Perraut, K., Perrin, G., Peterson, B.M., Petrucci, P.-O., Pflüger, A., Pfuhl, O., Phan Duc, T., Pineda, J.E., Plewa, P.M., Popovic, D., Pott, J.-U., Prieto, A., Pueyo, L., Rabien, S., Ramírez, A., Ramos, J.R., Rau, C., Ray, T., Riquelme, M., Rodríguez-Coira, G., Rohloff, R.-R., Rouan, D., Rousset, G., Sanchez-Bermudez, J., Schartmann, M., Scheithauer, S., Schöller, M., Schuhler, N., Segura-Cox, D., Shangguan, J., Shimizu, T.T., Spyromilio, J., Sternberg, A., Stock, M.R., Straub, O., Straubmeier, C., Sturm, E., Suárez Valles, M., Tacconi, L.J., Thi, W.-F., Tristram, K.R.W., Valenzuela, J.J., Boekel, R. van, Dishoeck, E.F. van, Vermot, P., Vincent, F., Von Fellenberg, S., Waisberg, I., Wang, J.J., Wank, I., Weber, J., Weigelt, G., Widmann, F., Wieprecht, E., Wiest, M., Wiezorrek, E., Wittkowski, M., Woillez, J., Wolff, B., Yang, P., Yazici, S., Ziegler, D., Zins, G., Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)
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General Relativity and Quantum Cosmology ,[SDU]Sciences of the Universe [physics] ,Astrophysics::High Energy Astrophysical Phenomena ,0103 physical sciences ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,010303 astronomy & astrophysics ,01 natural sciences ,Astrophysics::Galaxy Astrophysics - Abstract
The angular resolution of the Very Large Telescope Interferometer (VLTI) and the excellent sensitivity of GRAVITY have led to the first detection of spatially resolved kinematics of high velocity atomic gas near an accreting super- massive black hole, revealing rotation on sub-parsec scales in the quasar 3C 273 at a distance of 550 Mpc. The observations can be explained as the result of circular orbits in a thick disc configuration around a 300 million solar mass black hole. Within an ongoing Large Programme, this capability will be used to study the kinematics of atomic gas and its relation to hot dust in a sample of quasars and Seyfert galaxies. We will measure a new radius-luminosity relation from spatially resolved data and test the current methods used to measure black hole mass in large surveys., Published in The Messenger vol. 178, pp. 20-24, December 2019.
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- 2019
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15. Multiple Star Systems in the Orion Nebula
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Abuter, R., Accardo, M., Adler, T., Amorim, A., Anugu, N., Ávila, G., Bauböck, M., Benisty, M., Berger, J.-P., Bestenlehner, J. M., Beust, H., Blind, N., Bonnefoy, M., BONNET, H., Bourget, P., Bouvier, J., Brandner, W., Brast, R., Buron, A., Burtscher, L., Cantalloube, F., Caratti O Garatti, A., Caselli, P., Cassaing, F., Chapron, F., Charnay, B., Choquet, E., Clénet, Y., Collin, C., Coudé Du Foresto, V., Davies, R., Deen, C., Delplancke-Ströbele, F., Dembet, R., Derie, F., de Wit, W.-J., Dexter, J., De Zeeuw, T., Dougados, C., Dubus, G., Duvert, G., Ebert, M., Eckart, A., Eisenhauer, F., Esselborn, M., Eupen, F., Fédou, P., Ferreira, M. C., Finger, G., Förster Schreiber, N. M., Gao, F., García Dabó, C. E., Garcia Lopez, R., Garcia, P. J. V., Gendron, É., Genzel, R., Gerhard, O., Gil, J. P., Gillessen, S., Gonté, F., Gordo, P., Gratadour, D., Greenbaum, A., Grellmann, R., Grözinger, U., Guajardo, P., Guieu, S., Habibi, M., Haguenauer, P., Hans, O., Haubois, X., Haug, M., Haußmann, F., Henning, T., Hippler, S., Hönig, S. F., Horrobin, M., Huber, A., Hubert, Z., Hubin, N., Hummel, C. A., Jakob, G., Janssen, A., Jimenez Rosales, A., Jochum, L., Jocou, L., Kammerer, J., Karl, M., Kaufer, A., Kellner, S., Kendrew, S., Kern, L., Kervella, P., Kiekebusch, M., Kishimoto, M., Klarmann, L., Klein, R., Köhler, R., Kok, Y., Kolb, J., Koutoulaki, M., Kulas, M., Labadie, L., Lacour, S., Lagrange, A.-M., Lapeyrère, V., Laun, W., Lazareff, B., Le Bouquin, J.-B., Léna, P., Lenzen, R., Lévêque, S., Lin, C.-C., Lippa, M., Lutz, D., Magnard, Y., Maire, A.-L., Mehrgan, L., Mérand, A., Millour, F., Mollière, P., Moulin, T., Müller, A., Müller, E., Müller, F., Netzer, H., Neumann, U., Nowak, M., Oberti, S., Ott, T., Pallanca, L., Panduro, J., Pasquini, L., Paumard, T., Percheron, I., Perraut, K., Perrin, G., Peterson, B. M., Petrucci, P.-O., Pflüger, A., Pfuhl, O., Phan Duc, T., Pineda, J. E., Plewa, P. m., Popovic, D., Pott, J.-U., Prieto, A., Pueyo, L., Rabien, S., Ramírez, A., Ramos, J. R., Rau, C., Ray, T., Riquelme, M., Rodríguez-Coira, G., Rohloff, R.-R., Rouan, D., Rousset, G., Sanchez-Bermudez, J., Schartmann, M., Scheithauer, S., Schöller, M., Schuhler, N., Segura-Cox, D., Shangguan, J., Shimizu, T. T., Spyromilio, J., Sternberg, A., Stock, M. R., Straub, O., Straubmeier, C., Sturm, E., Suárez Valles, M., Tacconi, L. J., Thi, W.-F., Tristram, K. R. W., Valenzuela, J. J., Van Boekel, R., Van Dishoeck, E. F., Vermot, P., Vincent, F., Von fellenberg, S., Waisberg, I., Wang, J. J., Wank, I., Weber, J., Weigelt, G., Widmann, F., Wieprecht, E., Wiest, M., Wiezorrek, E., Wittkowski, M., Woillez, J., Wolff, B., Yang, P., Yazici, S., Ziegler, D., Zins, G., and European Southern Observatory (ESO)
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[SDU]Sciences of the Universe [physics] ,Astrophysics::Solar and Stellar Astrophysics ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Astrophysics::Galaxy Astrophysics - Abstract
GRAVITY observations reveal that most massive stars in the Orion Trapezium cluster live in multiple systems. Our deep, milliarcsecond-resolution interferometry fills the gap at 1–100 astronomical units (au), which is not accessible to traditional imaging and spectroscopy, but is crucial to uncovering the mystery of high-mass star formation.The new observations find a significantly higher companion fraction than earlier studies of mostly OB associations. The observed distribution of mass ratios declines steeply with mass and follows a Salpeter power-law initial mass function. The observations therefore exclude stellar mergers as the dominant formation mechanism for massive stars in Orion., Published in The Messenger vol. 178, pp. 36-38, December 2019.
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- 2019
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16. Spatially Resolving the Inner Gaseous Disc of the Herbig Star 51 Oph through its CO Ro-vibration Emission
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Abuter, R., Accardo, M., Adler, T., Amorim, A., Anugu, N., Ávila, G., Bauböck, M., Benisty, M., Berger, J.-P., Bestenlehner, J. M., Beust, H., Blind, N., Bonnefoy, M., BONNET, H., Bourget, P., Bouvier, J., Brandner, W., Brast, R., Buron, A., Burtscher, L., Cantalloube, F., Caratti O Garatti, A., Caselli, P., Cassaing, F., Chapron, F., Charnay, B., Choquet, E., Clénet, Y., Collin, C., Coudé Du Foresto, V., Davies, R., Deen, C., Delplancke-Ströbele, F., Dembet, R., Derie, F., de Wit, W.-J., Dexter, J., De Zeeuw, T., Dougados, C., Dubus, G., Duvert, G., Ebert, M., Eckart, A., Eisenhauer, F., Esselborn, M., Eupen, F., Fédou, P., Ferreira, M. C., Finger, G., Förster Schreiber, N. M., Gao, F., García Dabó, C. E., Garcia Lopez, R., Garcia, P. J. V., Gendron, É., Genzel, R., Gerhard, O., Gil, J. P., Gillessen, S., Gonté, F., Gordo, P., Gratadour, D., Greenbaum, A., Grellmann, R., Grözinger, U., Guajardo, P., Guieu, S., Habibi, M., Haguenauer, P., Hans, O., Haubois, X., Haug, M., Haußmann, F., Henning, T., Hippler, S., Hönig, S. F., Horrobin, M., Huber, A., Hubert, Z., Hubin, N., Hummel, C. A., Jakob, G., Janssen, A., Jimenez Rosales, A., Jochum, L., Jocou, L., Kammerer, J., Karl, M., Kaufer, A., Kellner, S., Kendrew, S., Kern, L., Kervella, P., Kiekebusch, M., Kishimoto, M., Klarmann, L., Klein, R., Köhler, R., Kok, Y., Kolb, J., Koutoulaki, M., Kulas, M., Labadie, L., Lacour, S., Lagrange, A.-M., Lapeyrère, V., Laun, W., Lazareff, B., Le Bouquin, J.-B., Léna, P., Lenzen, R., Lévêque, S., Lin, C.-C., Lippa, M., Lutz, D., Magnard, Y., Maire, A.-L., Mehrgan, L., Mérand, A., Millour, F., Mollière, P., Moulin, T., Müller, A., Müller, E., Müller, F., Netzer, H., Neumann, U., Nowak, M., Oberti, S., Ott, T., Pallanca, L., Panduro, J., Pasquini, L., Paumard, T., Percheron, I., Perraut, K., Perrin, G., Peterson, B. M., Petrucci, P.-O., Pflüger, A., Pfuhl, O., Phan Duc, T., Pineda, J. E., Plewa, P. m., Popovic, D., Pott, J.-U., Prieto, A., Pueyo, L., Rabien, S., Ramírez, A., Ramos, J. R., Rau, C., Ray, T., Riquelme, M., Rodríguez-Coira, G., Rohloff, R.-R., Rouan, D., Rousset, G., Sanchez-Bermudez, J., Schartmann, M., Scheithauer, S., Schöller, M., Schuhler, N., Segura-Cox, D., Shangguan, J., Shimizu, T. T., Spyromilio, J., Sternberg, A., Stock, M. R., Straub, O., Straubmeier, C., Sturm, E., Suárez Valles, M., Tacconi, L. J., Thi, W.-F., Tristram, K. R. W., Valenzuela, J. J., Van Boekel, R., Van Dishoeck, E. F., Vermot, P., Vincent, F., Von fellenberg, S., Waisberg, I., Wang, J. J., Wank, I., Weber, J., Weigelt, G., Widmann, F., Wieprecht, E., Wiest, M., Wiezorrek, E., Wittkowski, M., Woillez, J., Wolff, B., Yang, P., Yazici, S., Ziegler, D., Zins, G., and European Southern Observatory (ESO)
- Subjects
[SDU]Sciences of the Universe [physics] ,Astrophysics::Instrumentation and Methods for Astrophysics ,Astrophysics::Solar and Stellar Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics::Galaxy Astrophysics - Abstract
Near-infrared interferometry gives us the opportunity to spatially resolve the circumstellar environment of young stars at sub-astronomical-unit (au) scales, which a standalone telescope could not reach. In particular, the sensitivity of GRAVITY on the VLTI allows us to spatially resolve the CO overtone emission at 2.3 microns. In this article, we present a new method of using the model of the CO spectrum to reconstruct the differential phase signal and extract the geometry and size of the emitting region., Published in The Messenger vol. 178, pp. 40-42, December 2019.
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- 2019
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17. An Image of the Dust Sublimation Region in the Nucleus of NGC 1068
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Abuter, R., Accardo, M., Adler, T., Amorim, A., Anugu, N., Ávila, G., Bauböck, M., Benisty, M., Berger, J.-P., Bestenlehner, J. M., Beust, H., Blind, N., Bonnefoy, M., BONNET, H., Bourget, P., Bouvier, J., Brandner, W., Brast, R., Buron, A., Burtscher, L., Cantalloube, F., Caratti O Garatti, A., Caselli, P., Cassaing, F., Chapron, F., Charnay, B., Choquet, E., Clénet, Y., Collin, C., Coudé Du Foresto, V., Davies, R., Deen, C., Delplancke-Ströbele, F., Dembet, R., Derie, F., de Wit, W.-J., Dexter, J., De Zeeuw, T., Dougados, C., Dubus, G., Duvert, G., Ebert, M., Eckart, A., Eisenhauer, F., Esselborn, M., Eupen, F., Fédou, P., Ferreira, M. C., Finger, G., Förster Schreiber, N. M., Gao, F., García Dabó, C. E., Garcia Lopez, R., Garcia, P. J. V., Gendron, É., Genzel, R., Gerhard, O., Gil, J. P., Gillessen, S., Gonté, F., Gordo, P., Gratadour, D., Greenbaum, A., Grellmann, R., Grözinger, U., Guajardo, P., Guieu, S., Habibi, M., Haguenauer, P., Hans, O., Haubois, X., Haug, M., Haußmann, F., Henning, T., Hippler, S., Hönig, S. F., Horrobin, M., Huber, A., Hubert, Z., Hubin, N., Hummel, C. A., Jakob, G., Janssen, A., Jimenez Rosales, A., Jochum, L., Jocou, L., Kammerer, J., Karl, M., Kaufer, A., Kellner, S., Kendrew, S., Kern, L., Kervella, P., Kiekebusch, M., Kishimoto, M., Klarmann, L., Klein, R., Köhler, R., Kok, Y., Kolb, J., Koutoulaki, M., Kulas, M., Labadie, L., Lacour, S., Lagrange, A.-M., Lapeyrère, V., Laun, W., Lazareff, B., Le Bouquin, J.-B., Léna, P., Lenzen, R., Lévêque, S., Lin, C.-C., Lippa, M., Lutz, D., Magnard, Y., Maire, A.-L., Mehrgan, L., Mérand, A., Millour, F., Mollière, P., Moulin, T., Müller, A., Müller, E., Müller, F., Netzer, H., Neumann, U., Nowak, M., Oberti, S., Ott, T., Pallanca, L., Panduro, J., Pasquini, L., Paumard, T., Percheron, I., Perraut, K., Perrin, G., Peterson, B. M., Petrucci, P.-O., Pflüger, A., Pfuhl, O., Phan Duc, T., Pineda, J. E., Plewa, P. m., Popovic, D., Pott, J.-U., Prieto, A., Pueyo, L., Rabien, S., Ramírez, A., Ramos, J. R., Rau, C., Ray, T., Riquelme, M., Rodríguez-Coira, G., Rohloff, R.-R., Rouan, D., Rousset, G., Sanchez-Bermudez, J., Schartmann, M., Scheithauer, S., Schöller, M., Schuhler, N., Segura-Cox, D., Shangguan, J., Shimizu, T. T., Spyromilio, J., Sternberg, A., Stock, M. R., Straub, O., Straubmeier, C., Sturm, E., Suárez Valles, M., Tacconi, L. J., Thi, W.-F., Tristram, K. R. W., Valenzuela, J. J., Van Boekel, R., Van Dishoeck, E. F., Vermot, P., Vincent, F., Von fellenberg, S., Waisberg, I., Wang, J. J., Wank, I., Weber, J., Weigelt, G., Widmann, F., Wieprecht, E., Wiest, M., Wiezorrek, E., Wittkowski, M., Woillez, J., Wolff, B., Yang, P., Yazici, S., Ziegler, D., Zins, G., Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
[SDU]Sciences of the Universe [physics] ,Astrophysics::High Energy Astrophysical Phenomena ,0103 physical sciences ,Astrophysics::Solar and Stellar Astrophysics ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,010303 astronomy & astrophysics ,01 natural sciences ,Astrophysics::Galaxy Astrophysics - Abstract
The superb resolution of the Very Large Telescope Interferometer (VLTI) and the unrivalled sensitivity of GRAVITY have allowed us to reconstruct the first detailed image of the dust sublimation region in an active galaxy. In the nearby archetypal Seyfert 2 galaxy NGC 1068, the 2 µm continuum emission traces a highly inclined thin ring-like structure with a radius of 0.24 pc. The observed morphology challenges the picture of a geometrically and optically thick torus., Published in The Messenger vol. 178, pp. 24-26, December 2019.
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- 2019
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18. Probing the Discs of Herbig Ae/Be Stars at Terrestrial Orbits
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Abuter, R., Accardo, M., Adler, T., Amorim, A., Anugu, N., Ávila, G., Bauböck, M., Benisty, M., Berger, J.-P., Bestenlehner, J. M., Beust, H., Blind, N., Bonnefoy, M., BONNET, H., Bourget, P., Bouvier, J., Brandner, W., Brast, R., Buron, A., Burtscher, L., Cantalloube, F., Caratti O Garatti, A., Caselli, P., Cassaing, F., Chapron, F., Charnay, B., Choquet, E., Clénet, Y., Collin, C., Coudé Du Foresto, V., Davies, R., Deen, C., Delplancke-Ströbele, F., Dembet, R., Derie, F., de Wit, W.-J., Dexter, J., De Zeeuw, T., Dougados, C., Dubus, G., Duvert, G., Ebert, M., Eckart, A., Eisenhauer, F., Esselborn, M., Eupen, F., Fédou, P., Ferreira, M. C., Finger, G., Förster Schreiber, N. M., Gao, F., García Dabó, C. E., Garcia Lopez, R., Garcia, P. J. V., Gendron, É., Genzel, R., Gerhard, O., Gil, J. P., Gillessen, S., Gonté, F., Gordo, P., Gratadour, D., Greenbaum, A., Grellmann, R., Grözinger, U., Guajardo, P., Guieu, S., Habibi, M., Haguenauer, P., Hans, O., Haubois, X., Haug, M., Haußmann, F., Henning, T., Hippler, S., Hönig, S. F., Horrobin, M., Huber, A., Hubert, Z., Hubin, N., Hummel, C. A., Jakob, G., Janssen, A., Jimenez Rosales, A., Jochum, L., Jocou, L., Kammerer, J., Karl, M., Kaufer, A., Kellner, S., Kendrew, S., Kern, L., Kervella, P., Kiekebusch, M., Kishimoto, M., Klarmann, L., Klein, R., Köhler, R., Kok, Y., Kolb, J., Koutoulaki, M., Kulas, M., Labadie, L., Lacour, S., Lagrange, A.-M., Lapeyrère, V., Laun, W., Lazareff, B., Le Bouquin, J.-B., Léna, P., Lenzen, R., Lévêque, S., Lin, C.-C., Lippa, M., Lutz, D., Magnard, Y., Maire, A.-L., Mehrgan, L., Mérand, A., Millour, F., Mollière, P., Moulin, T., Müller, A., Müller, E., Müller, F., Netzer, H., Neumann, U., Nowak, M., Oberti, S., Ott, T., Pallanca, L., Panduro, J., Pasquini, L., Paumard, T., Percheron, I., Perraut, K., Perrin, G., Peterson, B. M., Petrucci, P.-O., Pflüger, A., Pfuhl, O., Phan Duc, T., Pineda, J. E., Plewa, P. m., Popovic, D., Pott, J.-U., Prieto, A., Pueyo, L., Rabien, S., Ramírez, A., Ramos, J. R., Rau, C., Ray, T., Riquelme, M., Rodríguez-Coira, G., Rohloff, R.-R., Rouan, D., Rousset, G., Sanchez-Bermudez, J., Schartmann, M., Scheithauer, S., Schöller, M., Schuhler, N., Segura-Cox, D., Shangguan, J., Shimizu, T. T., Spyromilio, J., Sternberg, A., Stock, M. R., Straub, O., Straubmeier, C., Sturm, E., Suárez Valles, M., Tacconi, L. J., Thi, W.-F., Tristram, K. R. W., Valenzuela, J. J., Van Boekel, R., Van Dishoeck, E. F., Vermot, P., Vincent, F., Von fellenberg, S., Waisberg, I., Wang, J. J., Wank, I., Weber, J., Weigelt, G., Widmann, F., Wieprecht, E., Wiest, M., Wiezorrek, E., Wittkowski, M., Woillez, J., Wolff, B., Yang, P., Yazici, S., Ziegler, D., Zins, G., and European Southern Observatory (ESO)
- Subjects
[SDU]Sciences of the Universe [physics] ,Astrophysics::Solar and Stellar Astrophysics ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics::Galaxy Astrophysics - Abstract
More than 4000 exoplanets are known to date in systems that differ greatly from our Solar System. In particular, inner exoplanets tend to follow orbits around their parent star that are much more compact than that of Earth. These systems are also extremely diverse, covering a range of intrinsic properties. Studying the main physi- cal processes at play in the innermost regions of the protoplanetary discs is crucial to understanding how these planets form and migrate so close to their host. With GRAVITY, we focused on the study of near-infrared emission of a sample of young intermediate- mass stars, the Herbig Ae/Be stars., Published in The Messenger vol. 178, pp. 38-40, December 2019.
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- 2019
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19. Deep Learning for Drug Discovery and Cancer Research: Automated Analysis of Vascularization Images
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Urban, Gregor, primary, Bache, Kevin, additional, Phan, Duc T. T., additional, Sobrino, Agua, additional, Shmakov, Alexander K., additional, Hachey, Stephanie J., additional, Hughes, Christopher C. W., additional, and Baldi, Pierre, additional
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- 2019
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20. First light for GRAVITY: Phase referencing optical interferometry for the Very Large Telescope Interferometer
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Abuter, Roberto, Accardo, Matteo, Antonio, Amorim, Narsireddy, Anugu, Avila, Gerardo, Azouaoui, N., Benisty, Myriam, Berger, Jean-Philippe, Blind, Nicolas, Bonnet, Henri, Bourget, Pierre, Brandner, Wolfgang, Brast, Roland, Buron, Alexander, Burtscher, L., Cassaing, Frederic, Chapron, Frédéric, Choquet, Elodie, Clénet, Yann, Collin, Claude, Coudé du Forestol, Vincent, de Wit, Willem-Jan, De Zeeuw, Tim, Casey, Deen, Delplancke-Ströbele, Françoise, Dembet, Roderick, Derie, Frédéric, Dexter, Jason, Duvert, Gilles, Ebert, Monica, Eckart, Andreas, Eisenhauer, Frank, Michael, Esselborn, Fédou, Pierre, Finger, Gert, Garcia, Paulo, Garcia Dabo, Cesar Enrique, Garcia Lopez, Rebeca, Gendron, Eric, Genzel, Reinhard, Gillessen, Stefan, Conté, Frédéric, Gordo, Paulo, Grould, Marion, Groözinger, Ulrich, Guieu, Sylvain, Haguenauer, Pierre, Hans, Olivier, Haubois, Xavier, Haug, Marcus, Haussmann, Frank, Henning, Thomas, Hippler, Stefan, Horrobin, Matthew, Huber, Armin, Hubert, Zoltan, Hubin, Norbert, Hummel, Christian, Jakob, Gerd, Janssen, A., Jochum, Lieselotte, Jocou, Laurent, Kaufer, Andreas, Kellner, Stefan, Kendrew, Sarah, Kern, Lothar, Kervella, Pierre, Kiekebusch, Mario, Klein, Ralf, Kok, Y., Kolb, Johan, Kulas, Martin, Lacour, Sylvestre, Lapeyrère, Vincent, Lazareff, Bernard, Le Bouquin, Jean-Baptiste, Léna, Pierre, Lenzen, Rainer, Levêque, Samuel, Lippa, Magdalena, Magnard, Yves, Mehrgan, Leander, Mellein, Marcus, Merand, Antoine, Moreno-Ventas, Javier, Moulin, Thibaut, Müller, Eric, Müller, Fredrich, Neumann, Udo, Oberti, Sylvain, Ott, Thomas, Pallanca, Laurent, Panduro, Johana, Pasquini, Luca, Paumard, Thibaut, Percheron, Isabelle, Perraut, Karine, Perrin, Guy, Pflüger, Andreas, Pfuhl, Olivier, Duc, Thanh Phan, Plewa, Philipp, Popovic, Dan, Rabien, Sebastian, Ramirez, Andres, Ramos, Jose, Rau, Christian, Riquelme, Miguel, Rohloff, Ralf-Rainer, Rousset, Gérard, Sanchez-Bermudez, Joel, Scheithauer, Sylvia, Schöller, Marcus, Schuhler, Nicolas, Spyromilio, Jason, Straubmeier, Christian, Sturm, Eckhard, Suarez, Marco, Tristram, Konrad, Ventura, Noel, Vincent, Frédéric, Waisberg, Idel, Wank, Imke, Weber, J., Wieprecht, Ekkehard, Wiest, Michael, Wiezorrek, Erich, Wittkowski, Markus, Woillez, Julien, Wolff, Burkhard, Yazici, Senol, Ziegler, Denis, Zins, Gérard, Amorim, A., Anugu, N., Ávila, G., Clenet, Y., Coudé Du Foresto, V., de Zeeuw, P., Deen, C., Esselborn, M., Dabo, C, Gonte, F., Grözinger, U., Henning, Th, Le Bouquin, J.-B, Lèna, P., Lévêque, S., Mérand, A., Muller, E., Muller, F., Phan Duc, T., Ramírez, A., Garcia Dabo, E., Henning, Th., Le Bouquin, B., Plewa, M., European Southern Observatory (ESO), CENTRA, Universidade de Lisboa, CENTRA, Universidade do Porto, Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Institut de Planétologie et d'Astrophysique de Grenoble (IPAG), Centre National d'Études Spatiales [Toulouse] (CNES)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Observatoire Astronomique de l'Université de Genève (ObsGE), Université de Genève (UNIGE), Max-Planck-Institut für Astronomie (MPIA), Max-Planck-Gesellschaft, Max Planck Institute for Extraterrestrial Physics (MPE), Leiden Observatory [Leiden], Universiteit Leiden [Leiden], ONERA - The French Aerospace Lab [Châtillon], ONERA, Physikalisches Institut [Köln], Universität zu Köln, Max Planck Institute for Radio Astronomy, Department of Physics [Berkeley], University of California [Berkeley], University of California-University of California, European Space Agency (ESA), European Southern Observatory [Santiago] (ESO), Institute Patology and Imunology Molecular, Fac Ciencias, Universidade do Porto [Porto], Brain Mind Institute (BMI - EPFL), Ecole Polytechnique Fédérale de Lausanne (EPFL), Technische Universität Dresden (TUD), Departamento de Control Automático (CINVESTAV-IPN), Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), Universidade do Porto, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), ONERA-Université Paris Saclay (COmUE), GRAVITY Collaboration, European Southern Observatory ( ESO ), Laboratoire d'études spatiales et d'instrumentation en astrophysique ( LESIA ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), Institut de Planétologie et d'Astrophysique de Grenoble ( IPAG ), Observatoire des Sciences de l'Univers de Grenoble ( OSUG ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA ) -Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA ) -Centre National de la Recherche Scientifique ( CNRS ), Observatoire Astronomique de l'Université de Genève ( ObsGE ), Université de Genève ( UNIGE ), Max-Planck-Institut für Astronomie ( MPIA ), Max Planck Institute for Extraterrestrial Physics ( MPE ), ONERA - The French Aerospace Lab ( Chatillon ), Max Planck Institute for Radio Astronomy, Bonn, European Space Agency ( ESA ), Universidad de Santiago de Chile [Santiago] ( USACH ), European Southern Observatory [Santiago] ( ESO ), University of Porto, Center for Brain Simulation, Ecole Polytechnique Fédérale de Lausanne, Technische Universität Dresden ( TUD ), Departamento de Control Automático ( CINVESTAV-IPN ), Center for Research and Advanced Studies of the National Polytechnic Institute ( CINVESTAV-IPN ), Universidade do Porto = University of Porto, Université de Genève = University of Geneva (UNIGE), Universiteit Leiden, Universität zu Köln = University of Cologne, University of California [Berkeley] (UC Berkeley), University of California (UC)-University of California (UC), and Agence Spatiale Européenne = European Space Agency (ESA)
- Subjects
[ SPI.SIGNAL ] Engineering Sciences [physics]/Signal and Image processing ,Astrophysics ,ÉTOILE DOUBLE ,OPTIQUE ADAPTATIVE ,01 natural sciences ,law.invention ,law ,Astrophysics::Solar and Stellar Astrophysics ,INSTRUMENTATION OPTIQUE ,INSTRUMENTATION ,instrumentation: interferometers ,010303 astronomy & astrophysics ,Physics ,Galaxy: center ,Galactic Center ,Astrophysics::Instrumentation and Methods for Astrophysics ,Astrometry ,[PHYS.PHYS.PHYS-SPACE-PH]Physics [physics]/Physics [physics]/Space Physics [physics.space-ph] ,[ PHYS.PHYS.PHYS-SPACE-PH ] Physics [physics]/Physics [physics]/Space Physics [physics.space-ph] ,quasars: emission lines ,Interferometry ,EMISSION LINE ,Closure phase ,binaries: symbiotic ,Astrophysics::Earth and Planetary Astrophysics ,[ SPI.OPTI ] Engineering Sciences [physics]/Optics / Photonic ,Astrophysics - Instrumentation and Methods for Astrophysics ,[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing ,CENTER ,INTERFEROMETRIE GRANDE BASE ,FOS: Physical sciences ,stars: pre-main sequence ,instrumentation: adaptive optics ,QUASAR ,010309 optics ,Telescope ,0103 physical sciences ,Angular resolution ,INTERFEROMETERS ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,CENTRE GALACTIQUE ,Astrophysics::Galaxy Astrophysics ,ADAPTIVE OPTICS ,Very Large Telescope ,Astronomy and Astrophysics ,First light ,GALAXY ,Space and Planetary Science ,[SPI.OPTI]Engineering Sciences [physics]/Optics / Photonic ,[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph] - Abstract
GRAVITY is a new instrument to coherently combine the light of the European Southern Observatory Very Large Telescope Interferometer to form a telescope with an equivalent 130 m diameter angular resolution and a collecting area of 200 m$^2$. The instrument comprises fiber fed integrated optics beam combination, high resolution spectroscopy, built-in beam analysis and control, near-infrared wavefront sensing, phase-tracking, dual beam operation and laser metrology [...]. This article gives an overview of GRAVITY and reports on the performance and the first astronomical observations during commissioning in 2015/16. We demonstrate phase tracking on stars as faint as m$_K$ ~ 10 mag, phase-referenced interferometry of objects fainter than m$_K$ ~ 15 mag with a limiting magnitude of m$_K$ ~ 17 mag, minute long coherent integrations, a visibility accuracy of better than 0.25 %, and spectro-differential phase and closure phase accuracy better than 0.5{\deg}, corresponding to a differential astrometric precision of better than 10 microarcseconds ({\mu}as). The dual-beam astrometry, measuring the phase difference of two objects with laser metrology, is still under commissioning. First observations show residuals as low as 50 {\mu}as when following objects over several months. We illustrate the instrument performance with the observations of archetypical objects for the different instrument modes. Examples include the Galactic Center supermassive black hole and its fast orbiting star S2 for phase referenced dual beam observations and infrared wavefront sensing, the High Mass X-Ray Binary BP Cru and the Active Galactic Nucleus of PDS 456 for few {\mu}as spectro-differential astrometry, the T Tauri star S CrA for a spectro-differential visibility analysis, {\xi} Tel and 24 Cap for high accuracy visibility observations, and {\eta} Car for interferometric imaging with GRAVITY., Comment: Accepted for publication in A&A, 23 pages, 23 figures, corresponding author: F. Eisenhauer
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- 2017
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21. A hydrostatic pressure-driven passive micropump enhanced with siphon-based autofill function
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Wang, Xiaolin, primary, Zhao, Da, additional, Phan, Duc T. T., additional, Liu, Jingquan, additional, Chen, Xiang, additional, Yang, Bin, additional, Hughes, Christopher C. W., additional, Zhang, Weijia, additional, and Lee, Abraham P., additional
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- 2018
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22. A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications
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Phan, Duc T. T., primary, Wang, Xiaolin, additional, Craver, Brianna M., additional, Sobrino, Agua, additional, Zhao, Da, additional, Chen, Jerry C., additional, Lee, Lilian Y. N., additional, George, Steven C., additional, Lee, Abraham P., additional, and Hughes, Christopher C. W., additional
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- 2017
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23. An overview of the mid-infrared spectro-interferometer MATISSE: science, concept, and current status
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Matter, A., additional, Lopez, B., additional, Antonelli, P., additional, Lehmitz, M., additional, Bettonvil, F., additional, Beckmann, U., additional, Lagarde, S., additional, Jaffe, W., additional, Petrov, R., additional, Berio, P., additional, Millour, F., additional, Robbe-Dubois, S., additional, Glindemann, A., additional, Bristow, P., additional, Schoeller, M., additional, Lanz, T., additional, Henning, T., additional, Weigelt, G., additional, Heininger, M., additional, Morel, S., additional, Cruzalebes, P., additional, Meisenheimer, K., additional, Hofferbert, R., additional, Wolf, S., additional, Bresson, Y., additional, Agocs, T., additional, Allouche, F., additional, Augereau, J.-C., additional, Avila, G., additional, Bailet, C., additional, Behrend, J., additional, van Belle, G., additional, Berger, J.-P., additional, van Boekel, R., additional, Bourget, P., additional, Brast, R., additional, Clausse, J.-M., additional, Connot, C., additional, Conzelmann, R., additional, Csepany, G., additional, Danchi, W. C., additional, Delbo, M., additional, Dominik, C., additional, van Duin, A., additional, Elswijk, E., additional, Fantei, Y., additional, Finger, G., additional, Gabasch, A., additional, Gonté, F., additional, Graser, U., additional, Guitton, F., additional, Guniat, S., additional, De Haan, M., additional, Haguenauer, P., additional, Hanenburg, H., additional, Hofmann, K.-H., additional, Hogerheijde, M., additional, ter Horst, R., additional, Hron, J., additional, Hummel, C, additional, Isderda, J., additional, Ives, D., additional, Jakob, G., additional, Jasko, A., additional, Jolley, P., additional, Kiraly, S., additional, Kragt, J., additional, Kroener, T., additional, Kroes, G., additional, Kuindersma, S., additional, Labadie, L., additional, Laun, W., additional, Leinert, C., additional, Lizon, J.-L., additional, Lucuix, C., additional, Marcotto, A., additional, Martinache, F., additional, Martinot-Lagarde, G., additional, Mauclert, N., additional, Mehrgan, L., additional, Meilland, A., additional, Mellein, M., additional, Menardi, S., additional, Merand, A., additional, Neumann, U., additional, Nussbaum, E., additional, Ottogalli, S., additional, Palsa, R., additional, Panduro, J., additional, Pantin, E., additional, Percheron, I., additional, Phan Duc, T., additional, Pott, J.-U., additional, Pozna, E., additional, Roelfsema, R., additional, Rupprecht, G., additional, Schertl, D., additional, Schmidt, C., additional, Schuil, M., additional, Spang, A., additional, Stegmeier, J., additional, Tromp, N., additional, Vakili, F., additional, Vannier, M., additional, Wagner, K., additional, Venema, L., additional, and Woillez, J., additional
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- 2016
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24. An on-chip microfluidic pressure regulator that facilitates reproducible loading of cells and hydrogels into microphysiological system platforms
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Wang, Xiaolin, primary, Phan, Duc T. T., additional, Zhao, Da, additional, George, Steven C., additional, Hughes, Christopher C. W., additional, and Lee, Abraham P., additional
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- 2016
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25. Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels
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Wang, Xiaolin, primary, Phan, Duc T. T., additional, Sobrino, Agua, additional, George, Steven C., additional, Hughes, Christopher C. W., additional, and Lee, Abraham P., additional
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- 2016
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26. PRIMA for the VLTI : a status report
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Delplancke, F., Andolfato, L., Ballester, P., De Jong, J.A., Derie, F.J., Duhoux, P., Frahm, R., Gitton, P.B., Glindemann, A., Karban, R., Lévêque, S.A., Ménardi, S., Phan Duc, T., Puech, F., Sahlmann, J., Schuler, N., Valat, B., Wallander, A., Laboratoire Hippolyte Fizeau (FIZEAU), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, and Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)
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n/a, SPIE n/a, (2006); International audience
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- 2006
27. Blood–brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood–central nervous system interface.
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Phan, Duc T. T., Bender, R. Hugh F., Andrejecsk, Jillian W., Sobrino, Agua, Hachey, Stephanie J., George, Steven C., and Hughes, Christopher C. W.
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- 2017
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28. Mid-infrared interferometry withKband fringe-tracking
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Müller, A., primary, Pott, J.-U., additional, Mérand, A., additional, Abuter, R., additional, Delplancke-Ströbele, F., additional, Henning, Th., additional, Köhler, R., additional, Leinert, Ch., additional, Morel, S., additional, Phan Duc, T., additional, Pozna, E., additional, Ramirez, A., additional, Sahlmann, J., additional, and Schmid, C., additional
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- 2014
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29. The VLTI and Its Subsystems
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Glindemann, A., Algomedo, J., Amestica, R., Ballester, P., Bauvir, B., Bugueño, E., Correia, S., Delgado, F., Delplancke, F., Derie, F., Duhoux, Ph, Di Folco, E., Alberto Gennai, Gilli, B., Giordano, P., Gitton, Ph, Guisard, S., Housen, N., Huxley, A., Kervella, P., Kiekebusch, M., Koehler, B., Lévêque, S., Longinotti, A., Ménardi, S., Morel, S., Paresce, F., Phan Duc, T., Richichi, A., Schöller, M., Tarenghi, M., Wallander, A., Wittkowski, M., Wilhelm, R., Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Pôle Astronomie du LESIA, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris
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[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph] - Abstract
International audience
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- 2002
30. Status of PRIMA for the VLTI: heading to astrometry
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Schmid, C., primary, Abuter, R., additional, Merand, A., additional, Sahlmann, J., additional, Alonso, J., additional, Andolfato, L., additional, van Belle, G., additional, Delplancke, F., additional, Dérie, F., additional, Di Lieto, N., additional, Frahm, R., additional, Gitton, Ph., additional, Gomes, N., additional, Haguenauer, P., additional, Justen, B., additional, Lévêque, S., additional, Ménardi, S., additional, Morel, S., additional, Müller, A., additional, Phan Duc, T., additional, Pozna, E., additional, Ramirez, A., additional, Schuhler, N., additional, and Ségransan, D., additional
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- 2012
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31. Perspective of imaging in the mid-infrared at the Very Large Telescope Interferometer
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Lopez, B., primary, Lagarde, S., additional, Antonelli, P., additional, Jaffe, W., additional, Petrov, R., additional, Venema, L., additional, Robbe-Dubois, Sylvie, additional, Bettonvil, F., additional, Berio, P., additional, Navarro, R., additional, Graser, U., additional, Beckman, U., additional, Weigelt, G., additional, Vakili, F., additional, Henning, T., additional, Gonzales, J.-C., additional, Wolf, S., additional, Bailet, C., additional, Behrend, J., additional, Bresson, Y., additional, Chesneau, O., additional, Clausse, J. M., additional, Connot, C., additional, Dugué, M., additional, Fantei, Y., additional, Elswijk, E., additional, Hanenburg, H., additional, Hofmann, K. H., additional, Heininger, M., additional, ter Horst, R., additional, Hron, J., additional, Kragt, J., additional, Tromp, N., additional, Agocs, T., additional, Kroes, G., additional, Laun, W., additional, Leinert, Ch., additional, Lehmitz, M., additional, Matter, A., additional, Menut, J. L., additional, Millour, F., additional, Neumann, U., additional, Nussbaum, E., additional, Ottogalli, S., additional, Pott, J.-U., additional, Rigal, F., additional, Roussel, A., additional, Schertl, D., additional, Vannier, M., additional, Wagner, K., additional, Mellein, M., additional, Kroener, T., additional, Mauclert, N., additional, Girard, P., additional, Lagarde, G. M., additional, Mosoni, L., additional, Jasko, A., additional, Glindemann, A., additional, Phan Duc, T., additional, Finger, G., additional, Ives, D., additional, Jakob, G., additional, Percheron, I., additional, Avila, G., additional, Palsa, R., additional, Pozna, E., additional, Lizon, J. L., additional, Lucuix, Ch., additional, Menardi, S., additional, Haguenauer, P., additional, Gitton, P., additional, Morel, S., additional, Gonté, F., additional, Jolley, P., additional, Rupprecht, G., additional, Bourget, P., additional, Delplancke, F., additional, Mehrgan, L., additional, Stegmeier, J., additional, van Belle, G., additional, Richichi, A., additional, and Moorwood, A., additional
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- 2012
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32. Status of PRIMA for the VLTI or the quest for user-friendly fringe tracking
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Schmid, C., primary, Abuter, R., additional, Ménardi, S., additional, Andolfato, L., additional, Delplancke, F., additional, Derie, F., additional, Di Lieto, N., additional, Frahm, R., additional, Gitton, Ph., additional, Gomes, N., additional, Haguenauer, P., additional, Lévêque, S., additional, Morel, S., additional, Müller, A., additional, Phan Duc, T., additional, Pozna, Eszter, additional, Sahlmann, J., additional, Schuhler, N., additional, and van Belle, G., additional
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- 2010
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33. First results from fringe tracking with the PRIMA fringe sensor unit
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Sahlmann, J., primary, Abuter, R., additional, Ménardi, S., additional, Schmid, C., additional, Di Lieto, N., additional, Delplancke, F., additional, Frahm, R., additional, Gomes, N., additional, Haguenauer, P., additional, Lévêque, S., additional, Morel, S., additional, Mueller, A., additional, Phan Duc, T., additional, Schuhler, N., additional, and van Belle, G., additional
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- 2010
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34. Commissioning the VLT interferometer: from first fringes toward a general user facility
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Schoeller, Markus, primary, Gitton, Philippe B., additional, Argomedo, Javier, additional, Ballester, Pascal, additional, Bauvir, Bertrand, additional, Van Boekel, Roy, additional, Cantzler, Michael, additional, Correia, Serge, additional, Cotton, William D., additional, Delplancke, Francoise, additional, Derie, Frederic, additional, Duhoux, Philippe, additional, Erm, Toomas, additional, di Folco, Emmanuel, additional, Coude du Foresto, Vincent, additional, Gennai, Alberto, additional, Gilli, Bruno, additional, Giordano, Paul, additional, Glindemann, Andreas, additional, Guisard, Stephane, additional, Gutierrez, Pablo, additional, Housen, Nico, additional, Huedepohl, Gerhard, additional, Huxley, Alexis, additional, Jackisch, S., additional, Jaffe, Walter, additional, Kervella, Pierre, additional, van Kesteren, Arno, additional, Kiekebusch, Mario, additional, Koehler, Bertrand, additional, Leveque, Samuel A., additional, Longinotti, Antonio, additional, Menardi, Serge, additional, Morel, Sebastien, additional, Noethe, Lothar, additional, Paresce, Francesco, additional, Percheron, Isabelle, additional, Phan Duc, T., additional, Pino, A., additional, Rabeling, D., additional, Ramirez, A., additional, Robbe-Dubois, Sylvie, additional, Richichi, Andrea, additional, Rijo, A., additional, Sabet, Cyrus, additional, Sandrock, Stefan, additional, Segransan, Damien, additional, Spyromilio, Jason, additional, Tamai, Roberto, additional, Tarenghi, Massimo, additional, Wallander, Anders, additional, Wilhelm, Rainer, additional, and Wittkowski, Markus, additional
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- 2003
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35. The VLTI and its Subsystems
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Glindemann, A., primary, Algomedo, J., additional, Amestica, R., additional, Ballester, P., additional, Bauvir, B., additional, Bugueño, E., additional, Cabanero, S., additional, Correia, S., additional, Delgado, F., additional, Delplancke, F., additional, Derie, F., additional, Duhoux, Ph., additional, di Folco, E., additional, Gennai, A., additional, Gilli, B., additional, Giordano, P., additional, Gitton, Ph., additional, Guisard, S., additional, Housen, N., additional, Huxley, A., additional, Kervella, P., additional, Kiekebusch, M., additional, Koehler, B., additional, Lévêque, S., additional, Longinotti, A., additional, Ménardi, S., additional, Morel, S., additional, Paresce, F., additional, Phan Duc, T., additional, Richichi, A., additional, Schöller, M., additional, Tarenghi, M., additional, Wallander, A., additional, Wittkowski, M., additional, and Wilhelm, R., additional
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- 2003
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36. The VINCI instrument software in the very large telescope environment
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Longinotti, A., primary, Bickert, K., additional, Cautain, R., additional, Dupin, J.P., additional, Kervella, P., additional, Kiekebush, M., additional, Phan Duc, T., additional, Tilloles, P., additional, and Valentin, H., additional
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- 2002
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37. An overview of the mid-infrared spectro-interferometer MATISSE: science, concept, and current status
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Malbet, Fabien, Creech-Eakman, Michelle J., Tuthill, Peter G., Matter, A., Lopez, B., Antonelli, P., Lehmitz, M., Bettonvil, F., Beckmann, U., Lagarde, S., Jaffe, W., Petrov, R., Berio, P., Millour, F., Robbe-Dubois, S., Glindemann, A., Bristow, P., Schoeller, M., Lanz, T., Henning, T., Weigelt, G., Heininger, M., Morel, S., Cruzalebes, P., Meisenheimer, K., Hofferbert, R., Wolf, S., Bresson, Y., Agocs, T., Allouche, F., Augereau, J.-C., Avila, G., Bailet, C., Behrend, J., van Belle, G., Berger, J.-P., van Boekel, R., Bourget, P., Brast, R., Clausse, J.-M., Connot, C., Conzelmann, R., Csepany, G., Danchi, W. C., Delbo, M., Dominik, C., van Duin, A., Elswijk, E., Fantei, Y., Finger, G., Gabasch, A., Gonté, F., Graser, U., Guitton, F., Guniat, S., De Haan, M., Haguenauer, P., Hanenburg, H., Hofmann, K.-H., Hogerheijde, M., ter Horst, R., Hron, J., Hummel, C, Isderda, J., Ives, D., Jakob, G., Jasko, A., Jolley, P., Kiraly, S., Kragt, J., Kroener, T., Kroes, G., Kuindersma, S., Labadie, L., Laun, W., Leinert, C., Lizon, J.-L., Lucuix, C., Marcotto, A., Martinache, F., Martinot-Lagarde, G., Mauclert, N., Mehrgan, L., Meilland, A., Mellein, M., Menardi, S., Merand, A., Neumann, U., Nussbaum, E., Ottogalli, S., Palsa, R., Panduro, J., Pantin, E., Percheron, I., Phan Duc, T., Pott, J.-U., Pozna, E., Roelfsema, R., Rupprecht, G., Schertl, D., Schmidt, C., Schuil, M., Spang, A., Stegmeier, J., Tromp, N., Vakili, F., Vannier, M., Wagner, K., Venema, L., and Woillez, J.
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- 2016
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38. Mid-infrared interferometry with K band fringe-tracking: I. The VLTI MIDI+FSU experiment.
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Müller, A., Pott, J.-U., Mérand, A., Abuter, R., Delplancke-Ströbele, F., Henning, Th., Köhler, R., Leinert, Ch., Morel, S., Phan Duc, T., Pozna, E., Ramirez, A., Sahlmann, J., and Schmid, C.
- Subjects
ATMOSPHERIC turbulence ,INTERFEROMETRY ,HIGH resolution imaging ,BEAM splitters ,DATA analysis ,ENERGY bands - Abstract
Context. A turbulent atmosphere causes atmospheric piston variations leading to rapid changes in the optical path difference of an interferometer, which causes correlated flux losses. This leads to decreased sensitivity and accuracy in the correlated flux measurement. Aims. To stabilize the N band interferometric signal in MIDI (MID-infrared Interferometric instrument), we use an external fringe tracker working in K band, the so-called FSU-A (fringe sensor unit) of the PRIMA (Phase-Referenced Imaging and Micro-arcsecond Astrometry) facility at VLTI. We present measurements obtained using the newly commissioned and publicly offered MIDI+FSU-A mode. A first characterization of the fringe-tracking performance and resulting gains in the N band are presented. In addition, we demonstrate the possibility of using the FSU-A to measure visibilities in the K band. Methods. We analyzed FSU-A fringe track data of 43 individual observations covering different baselines and object K band magnitudes with respect to the fringe-tracking performance. The N band group delay and phase delay values could be predicted by computing the relative change in the differential water vapor column density from FSU-A data. Visibility measurements in the K band were carried out using a scanning mode of the FSU-A. Results. Using the FSU-A K band group delay and phase delay measurements, we were able to predict the corresponding N band values with high accuracy with residuals of less than 1 μm. This allows the coherent integration of the MIDI fringes of faint or resolved N band targets, respectively. With that method we could decrease the detection limit of correlated fluxes of MIDI down to 0.5 Jy (vs. 5 Jy without FSU-A) and 0.05 Jy (vs. 0.2 Jy without FSU-A) using the ATs and UTs, respectively. The K band visibilities could be measured with a precision down to ≈2%. [ABSTRACT FROM AUTHOR]
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- 2014
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39. Light at the end of the tunnel - first fringes with the VLTI
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Glindemann, A., Bauvir, B., Delplancke, F., Derie, F., Di Folco, E., Gennai, A., Gitton, P., Housen, N., Huxley, A., Kervella, P., Koehler, B., Lévêque, S., Longinotti, A., Ménardi, S., Morel, S., Paresce, F., Phan Duc, T., Richichi, A., Schöller, M., Tarenghi, M., Wallander, A., Markus Wittkowski, and Wilhelm, R.
40. First fringes with ANTU and MELIPAL
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Glindemann, A., Ballester, P., Bauvir, B., Bugueño, E., Cantzler, M., Correia, S., Delplancke, F., Derie, F., Duhoux, P., Di Folco, E., Gennai, A., Gilli, B., Giordano, P., Gitton, P., Guisard, S., Housen, N., Huxley, A., Kervella, P., Kiekebusch, M., Koehler, B., Lévêque, S., Longinotti, A., Lopez, A., Ménardi, S., Morel, S., Paresce, F., Phan Duc, T., Ramirez, A., Richichi, A., Markus Schoeller, Spyromilio, J., Tarenghi, M., Wallander, A., Wilhelm, R., and Wittkowski, M.
41. Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs.
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Liu Y, Sakolish C, Chen Z, Phan DTT, Bender RHF, Hughes CCW, and Rusyn I
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- Antineoplastic Agents pharmacology, Cell Culture Techniques, Dose-Response Relationship, Drug, Endothelial Cells drug effects, Endothelial Cells pathology, HCT116 Cells, Human Umbilical Vein Endothelial Cells physiology, Humans, Neoplasms drug therapy, Neovascularization, Pathologic drug therapy, Organ Culture Techniques, Reproducibility of Results, Antineoplastic Agents therapeutic use, Human Umbilical Vein Endothelial Cells drug effects, Lab-On-A-Chip Devices, Microfluidic Analytical Techniques methods, Neoplasms pathology, Neovascularization, Pathologic pathology
- Abstract
Angiogenesis is a complex process that is required for development and tissue regeneration and it may be affected by many pathological conditions. Chemicals and drugs can impact formation and maintenance of the vascular networks; these effects may be both desirable (e.g., anti-cancer drugs) or unwanted (e.g., side effects of drugs). A number of in vivo and in vitro models exist for studies of angiogenesis and endothelial cell function, including organ-on-a-chip microphysiological systems. An arrayed organ-on-a-chip platform on a 96-well plate footprint that incorporates perfused microvessels, with and without tumors, was recently developed and it was shown that survival of the surrounding tissue was dependent on delivery of nutrients through the vessels. Here we describe a technology transfer of this complex microphysiological model between laboratories and demonstrate that reproducibility and robustness of these tissue chip-enabled experiments depend primarily on the source of the endothelial cells. The model was highly reproducible between laboratories and was used to demonstrate the advantages of the perfusable vascular networks for drug safety evaluation. As a proof-of-concept, we tested Fluorouracil (1-1,000 μM), Vincristine (1-1,000 nM), and Sorafenib (0.1-100 μM), in the perfusable and non-perfusable micro-organs, and in a colon cancer-containing micro-tumor model. Tissue chip experiments were compared to the traditional monolayer cultures of endothelial or tumor cells. These studies showed that human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs. The data from the 3D models confirmed advantages of the physiological environment as compared to 2D cell cultures. We demonstrated how these models can be translated into practice by verifying that the endothelial cell source and passage are critical elements for establishing a perfusable model., (Copyright © 2020 Elsevier B.V. All rights reserved.)
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- 2020
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42. Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions.
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Faal T, Phan DTT, Davtyan H, Scarfone VM, Varady E, Blurton-Jones M, Hughes CCW, and Inlay MA
- Subjects
- Alzheimer Disease metabolism, Alzheimer Disease pathology, Biomarkers metabolism, Blood-Brain Barrier metabolism, Blood-Brain Barrier pathology, Brain metabolism, Brain pathology, Brain physiology, Humans, Mesoderm metabolism, Mesoderm pathology, Neural Crest metabolism, Neural Crest pathology, Pericytes metabolism, Pericytes pathology, Pluripotent Stem Cells metabolism, Pluripotent Stem Cells pathology, Tight Junctions metabolism, Tight Junctions pathology, Tight Junctions physiology, Blood-Brain Barrier physiology, Induced Pluripotent Stem Cells physiology, Mesoderm physiology, Neural Crest physiology, Pericytes physiology, Pluripotent Stem Cells physiology
- Abstract
In the CNS, perivascular cells ("pericytes") associate with endothelial cells to mediate the formation of tight junctions essential to the function of the blood-brain barrier (BBB). The BBB protects the CNS by regulating the flow of nutrients and toxins into and out of the brain. BBB dysfunction has been implicated in the progression of Alzheimer's disease (AD), but the role of pericytes in BBB dysfunction in AD is not well understood. In the developing embryo, CNS pericytes originate from two sources: mesoderm and neural crest. In this study, we report two protocols using mesoderm or neural crest intermediates, to generate brain-specific pericyte-like cells from induced pluripotent stem cell (iPSC) lines created from healthy and AD patients. iPSC-derived pericytes display stable expression of pericyte surface markers and brain-specific genes and are functionally capable of increasing vascular tube formation and endothelial barrier properties., (Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2019
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43. 3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels.
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Wang X, Phan DTT, George SC, Hughes CCW, and Lee AP
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- Cells, Cultured, Humans, Lab-On-A-Chip Devices, Microfluidics instrumentation, Models, Biological, Tissue Engineering instrumentation, Tissue Engineering methods, Capillaries cytology, Endothelial Cells cytology, Microfluidics methods
- Abstract
This protocol describes detailed practical procedures for generating 3D intact and perfusable microvascular network that connects to microfluidic channels without appreciable leakage. This advanced 3D microvascular network model incorporates different stages of vascular development including vasculogenesis, endothelial cell (EC) lining, sprouting angiogenesis, and anastomosis in sequential order. The capillary network is first induced via vasculogenesis in a middle tissue chamber and then EC linings along the microfluidic channel on either side serve as artery and vein. The anastomosis is then induced by sprouting angiogenesis to facilitate tight interconnection between the artery/vein and the capillary network. This versatile device design and its robust construction methodology establish a physiological microcirculation transport model of interconnected perfused vessels from artery to vascularized tissue to vein.
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- 2017
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44. Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering.
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Arulmoli J, Wright HJ, Phan DTT, Sheth U, Que RA, Botten GA, Keating M, Botvinick EL, Pathak MM, Zarembinski TI, Yanni DS, Razorenova OV, Hughes CCW, and Flanagan LA
- Subjects
- Animals, Blood Vessels drug effects, Cattle, Cell Differentiation drug effects, Cell Proliferation drug effects, Endothelial Cells cytology, Endothelial Cells drug effects, Endothelial Cells metabolism, Extracellular Matrix metabolism, Humans, Hydrogel, Polyethylene Glycol Dimethacrylate pharmacology, Integrins metabolism, Neovascularization, Physiologic drug effects, Neural Stem Cells drug effects, Polymerization drug effects, Salmon, Blood Vessels physiology, Fibrin pharmacology, Hyaluronic Acid pharmacology, Laminin pharmacology, Neural Stem Cells cytology, Tissue Engineering methods, Tissue Scaffolds chemistry
- Abstract
Unlabelled: Human neural stem/progenitor cells (hNSPCs) are good candidates for treating central nervous system (CNS) trauma since they secrete beneficial trophic factors and differentiate into mature CNS cells; however, many cells die after transplantation. This cell death can be ameliorated by inclusion of a biomaterial scaffold, making identification of optimal scaffolds for hNSPCs a critical research focus. We investigated the properties of fibrin-based scaffolds and their effects on hNSPCs and found that fibrin generated from salmon fibrinogen and thrombin stimulates greater hNSPC proliferation than mammalian fibrin. Fibrin scaffolds degrade over the course of a few days in vivo, so we sought to develop a novel scaffold that would retain the beneficial properties of fibrin but degrade more slowly to provide longer support for hNSPCs. We found combination scaffolds of salmon fibrin with interpenetrating networks (IPNs) of hyaluronic acid (HA) with and without laminin polymerize more effectively than fibrin alone and generate compliant hydrogels matching the physical properties of brain tissue. Furthermore, combination scaffolds support hNSPC proliferation and differentiation while significantly attenuating the cell-mediated degradation seen with fibrin alone. HNSPCs express two fibrinogen-binding integrins, αVβ1 and α5β1, and several laminin binding integrins (α7β1, α6β1, α3β1) that can mediate interaction with the scaffold. Lastly, to test the ability of scaffolds to support vascularization, we analyzed human cord blood-derived endothelial cells alone and in co-culture with hNSPCs and found enhanced vessel formation and complexity in co-cultures within combination scaffolds. Overall, combination scaffolds of fibrin, HA, and laminin are excellent biomaterials for hNSPCs., Statement of Significance: Interest has increased recently in the development of biomaterials as neural stem cell transplantation scaffolds to treat central nervous system (CNS) injury since scaffolds improve survival and integration of transplanted cells. We report here on a novel combination scaffold composed of fibrin, hyaluronic acid, and laminin to support human neural stem/progenitor cell (hNSPC) function. This combined biomaterial scaffold has appropriate physical properties for hNSPCs and the CNS, supports hNSPC proliferation and differentiation, and attenuates rapid cell-mediated scaffold degradation. The hNSPCs and scaffold components synergistically encourage new vessel formation from human endothelial cells. This work marks the first report of a combination scaffold supporting human neural and vascular cells to encourage vasculogenesis, and sets a benchmark for biomaterials to treat CNS injury., (Copyright © 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2016
- Full Text
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