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Aim: To propose optimal policy of pregnancy and labor management in females with solitary kidney., Material and Methods: The study included 102 pregnant women who had contracted or transplanted donor kidney, renal aplasia (17, 3 and 28 females, respectively) or had undergone nephrectomy for different diseases (n = 54). Filtration, concentration, nitrogen-eliminating renal functions, renal hemodynamics, bacteriological picture of the urine were examined. Also, ultrasonography of the kidneys, cardiotocographic monitoring, ultrasonic fetal biometry, dopplerometry of placental blood flow were made., Results: Most of the pregnant women showed declined function of the solitary kidney, but renal insufficiency was a rare finding. Pyelonephritis of the solitary kidney, on the contrary, occurred rather frequently (77.8%) causing intrauterine infection in 46% of the fetuses. Obstetric complications arose more frequently than in women with two kidneys: gestosis--28%, threatened abortion--18%, premature delivery--25%. Hypotrophy was registered in 23% of the newborns. Adequate management of pregnancy reduced stillbirth rate to only 5%. 78% of the neonates were born mature and had normal body mass., Conclusion: Solitary kidney is not contraindication to pregnancy while pyelonephritis exacerbation--to abortion. Pregnancy is contraindicated in chronic renal failure.

Aim: To study clinical efficiency of atenolol in pregnancy hypertension with consideration of its cardiodynamic effects., Material and Methods: The trial included 36 women aged 19 to 41 years on pregnancy week 32 to 38. This study group had gestosis of the 1st and 2nd degree. Control group consisted of 14 healthy women with physiological pregnancy. All the examinees underwent atenolol test: measurement of heart rate, arterial pressure and ECG before, 30 and 90 min after introduction of a single atenolol dose 50 mg. Echo-CG was registered before and 90 min after administration of 50 mg amenolol, and on the treatment day 5., Results: The response to atenolol in combined therapy of gestosis is the highest in gravidae with hyperkinetic type of circulation., Conclusion: Determination of the hemodynamic type is necessary for selection of antihypertensive drugs for treatment of gestosis.

The paper presents 24 cases of pregnancy and labor in women with kidney aplasia complicated by reproductive system anomalies and affections of the solitary kidney (pyelonephritis, hydronephrosis). Pregnancy contraindications for such patients are determined. Pregnancy outcome prognosis was favorable in intact renal function and absence of infection. Chronic pyelonephritis and renal insufficiency worsen the prognosis.