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1. The impact of vaccination status on post-acute sequelae in hospitalized COVID-19 survivors using a multi-disciplinary approach: An observational single center study

Author

Lucia Ilaria Birtolo, Gianluca Di Pietro, Antonella Ciuffreda, Riccardo Improta, Sara Monosilio, Silvia Prosperi, Sara Cimino, Nicola Galea, Paolo Severino, Gioacchino Galardo, Maria Chiara Colaiacomo, Patrizia Pasculli, Angelo Petroianni, Paolo Palange, Claudio Maria Mastroianni, Laura de Vito, Carlo Catalano, Francesco Pugliese, Maria Rosa Ciardi, Paola Celli, Roberto Badagliacca, Francesco Fedele, Carmine Dario Vizza, Viviana Maestrini, Massimo Mancone, Agnes Gianluca, Albante Alida, Alfarano Maria, Araimo Morselli Fabio, Auricchio Daniela, Barletta Giovanna, Bilotta Federico, Brisciani Matteo, Bruno Katia, Bucarelli Maria Clelia, Cappannoli Alessandro, Ceccarelli Giancarlo, Celli Paola, Consolo Stella, Consoli Giulia, Croce Claudia, Crocitti Beatrice, D'Antoni Letizia, De Lazzaro Francesco, De Lauri Daniela, De Persis Francesca, De Rose Maria, Del Bianco Andrea, Di Bella Valerio, Di Sano Laura, Di Santo Carmela, Filomena Domenico, Giannetti Lorena, Giordano Giovanni, Ianni Stefano, Imperiale Carmela, Magnanimi Eugenia, Manganelli Chiara, Maldarelli Federica, Manzi Giovanna, Marcon Serena, Mariani Marco Valerio, Martelli Sabina, Messina Teresa, Neccia Matteo, Novelli Martina, Papa Silvia, Pasqualitto Fabiola, Pattelli Elisa, Pecorari Filippo, Perrella Serena, Passarelli Ilaria, Piazzolla Mario, Piro Agostino, Portieri Monica, Ratini Fabiola, Ricci Claudia, Romano Hilde, Sabani Anna, Santopietro Pietro, Tanzilli Alessandra, Tellan Guglielmo, Titi Luca, Tocci Marco, Tordiglione Paolo, Tosi Antonella, Trigilia Fausto, Verduci Noemi, and Vaccaro Paola

Subjects
Long-COVID19, mRNA vaccines, Hospitalized, Survivors, Sequalae, Science (General), Q1-390, Social sciences (General), H1-99
Abstract

Background: COVID-19 vaccines reduced mortality, hospitalizations and ICUs admissions. Conversely, the impact of vaccination on Long COVID-19 syndrome is still unclear. This study compared the prevalence of post-acute sequelae at short and long-term follow-up among hospitalized unvaccinated and vaccinated COVID-19 survivors through a multidisciplinary approach. Methods: After 2 months from discharge, unvaccinated and vaccinated COVID-19 survivors underwent a follow-up visit at a dedicated “post-COVID-19 Outpatient Clinic”. The follow-up visit included a cardiovascular evaluation, blood tests, chest computed tomography, 6-min walking test (6MWT), spirometry. A one-year telephone follow-up was performed to assess re-hospitalizations, death and long-lasting symptoms. An additional 1:1 case-control matching analysis adjusted for baseline characteristics was performed. Results: Between June 2020 and June 2022, a total of 458 unvaccinated and vaccinated patients (229 per group) underwent the follow-up visit. Vaccinated patients had lower rates of ICU admissions (1.7 % vs 9.6 %, p=

Published
2024
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2. Noninvasive mechanical ventilation on the ward for severe COPD: still unresolved question of balance among safety and drawbacks?

Author

Petroianni A and Esquinas AM

Subjects
noninvasive ventilation, COPD, failure, ward, Diseases of the respiratory system, RC705-779
Abstract

Angelo Petroianni,1 Antonio M Esquinas2 1Department of Cardiovascular and Respiratory diseases, Sapienza University of Rome, Rome, Italy; 2Intensive Care and Noninvasive Ventilatory Unit, Hospital General Universitario Morales Meseguer, Murcia, SpainWe read with interest the study by Yalcinsoy et al1 appreciating its relevance and clinical practice value. In the last decades, noninvasive ventilation (NIV) has revolutionized the management of acute respiratory failure (ARF) reducing the need for endotracheal intubation and its associated complications and also reducing the complications associated with a stay in the intensive care unit, the length of hospital stay, and mortality.2View the original paper by Yalcinsoy and colleagues.

Published
2016

3. The impact of vaccination status on post-acute sequelae in hospitalized COVID-19 survivors using a multi-disciplinary approach: An observational single center study

Author

Gianluca, Agnes, Alida, Albante, Maria, Alfarano, Fabio, Araimo Morselli, Daniela, Auricchio, Giovanna, Barletta, Federico, Bilotta, Matteo, Brisciani, Katia, Bruno, Clelia, Bucarelli Maria, Alessandro, Cappannoli, Giancarlo, Ceccarelli, Paola, Celli, Stella, Consolo, Giulia, Consoli, Claudia, Croce, Beatrice, Crocitti, Letizia, D'Antoni, Francesco, De Lazzaro, Daniela, De Lauri, Francesca, De Persis, Maria, De Rose, Andrea, Del Bianco, Valerio, Di Bella, Laura, Di Sano, Carmela, Di Santo, Domenico, Filomena, Lorena, Giannetti, Giovanni, Giordano, Stefano, Ianni, Carmela, Imperiale, Eugenia, Magnanimi, Chiara, Manganelli, Federica, Maldarelli, Giovanna, Manzi, Serena, Marcon, Valerio, Mariani Marco, Sabina, Martelli, Teresa, Messina, Matteo, Neccia, Martina, Novelli, Silvia, Papa, Fabiola, Pasqualitto, Elisa, Pattelli, Filippo, Pecorari, Serena, Perrella, Ilaria, Passarelli, Mario, Piazzolla, Agostino, Piro, Monica, Portieri, Fabiola, Ratini, Claudia, Ricci, Hilde, Romano, Anna, Sabani, Pietro, Santopietro, Alessandra, Tanzilli, Guglielmo, Tellan, Luca, Titi, Marco, Tocci, Paolo, Tordiglione, Antonella, Tosi, Fausto, Trigilia, Noemi, Verduci, Paola, Vaccaro, Birtolo, Lucia Ilaria, Di Pietro, Gianluca, Ciuffreda, Antonella, Improta, Riccardo, Monosilio, Sara, Prosperi, Silvia, Cimino, Sara, Galea, Nicola, Severino, Paolo, Galardo, Gioacchino, Colaiacomo, Maria Chiara, Pasculli, Patrizia, Petroianni, Angelo, Palange, Paolo, Mastroianni, Claudio Maria, de Vito, Laura, Catalano, Carlo, Pugliese, Francesco, Ciardi, Maria Rosa, Celli, Paola, Badagliacca, Roberto, Fedele, Francesco, Vizza, Carmine Dario, Maestrini, Viviana, and Mancone, Massimo

Published
2024
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4. High-Flow Nasal Oxygen Therapy in Acute Hypoxemic Respiratory Failure: Concise Review on Technology and Initial Methodology.

Author

Guia, Miguel, Alpay, Nilgun, Gerardo, António, Madney, Yasmin, Abdelrahim, Mohamed, Saeed, Haitham, Harb, Hadeer, Gonçalves, Gil, Cabrita, Bruno, Alqahtani, Jaber, El-Khatib, Mohamad, Gómez-Ríos, Manuel, Fakharian, Atefeh, Ciobanu, Laura, Karim, Habib, Piervincenzi, Edoardo, Scharffenberg, Martin, Steiropoulos, Paschalis, LeMaster, William, Barjaktarevic, Igor, Wittenstein, Jakob, Diaz-Abad, Montserrat, Perren, Andreas, Nicolini, Antonello, Spadaro, Savino, Garuti, Giancarlo, Petroianni, Angelo, and Esquinas, Antonio

Abstract

High-flow nasal cannula oxygen therapy (HFNCOT) system consists of an air/oxygen supply system capable of delivering up to 100% humidified and heated oxygen at a flow rate of up to 80 L/min. The system includes a blender, active humidifier, single heated tube, and nasal cannula. HFNCOT has many physiological advantages compared with other standard oxygen therapies, such as anatomical dead space washout, more constant fraction of inspired oxygen, positive end-expiratory (PEEP) effect, supplement of adequate humidification and maintenance of muco-ciliary function. HFNCOT is mostly used for hypoxemic acute respiratory failure, although it also has other indications. HFNCOT is a common choice of physicians as its technology makes it more silent and comfortable. Though HFNCOT is used in many clinical settings, there is a lack of publications addressing devices and initial settings. We present a review on HFNCOT, with focus on device and application methodology.

Published
2021

5. Maximal respiratory static pressures in patients with different stages of COPD severity

Author

Ricci Alberto, Graziani Elda, Conti Vittoria, Ceccarelli Daniela, Terzano Claudio, and Petroianni Angelo

Subjects
Diseases of the respiratory system, RC705-779
Abstract

Abstract Background In this study, we analyzed maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) values in a stable COPD population compared with normal subjects. We evaluated the possible correlation between functional maximal respiratory static pressures and functional and anthropometric parameters at different stages of COPD. Furthermore, we considered the possible correlation between airway obstruction and MIP and MEP values. Subject and methods 110 patients with stable COPD and 21 age-matched healthy subjects were enrolled in this study. Patients were subdivided according to GOLD guidelines: 31 mild, 39 moderate and 28 severe. Results Both MIP and MEP were lower in patients with severe airway impairment than in normal subjects. Moreover, we found a correlation between respiratory muscle function and some functional and anthropometric parameters: FEV1 (forced expiratory volume in one second), FVC (forced vital capacity), PEF (peak expiratory flow), TLC (total lung capacity) and height. MIP and MEP values were lower in patients with severe impairment than in patients with a slight reduction of FEV1. Conclusion The measurement of MIP and MEP indicates the state of respiratory muscles, thus providing clinicians with a further and helpful tool in monitoring the evolution of COPD.

Published
2008
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7. Conservative oxygen supplementation during helmet continuous positive airway pressure therapy in patients with COVID-19 and respiratory failure: a pilot study

Author

Alessandra Iacovelli, Maria Luisa Nicolardi, Valentina Baccolini, Federica Olmati, Ilenia Attilia, Pia Baiocchi, Letizia D'Antoni, Ilaria Menichini, Ambra Migliarini, Daniela Pellegrino, Angelo Petroianni, Daniel Piamonti, Angela Tramontano, Paolo Villari, and Paolo Palange

Subjects
Medicine
Abstract

Background Respiratory failure is a severe complication in coronavirus disease 2019 (COVID-19) pneumonia that, in addition to oxygen therapy, may require continuous positive airway pressure (CPAP) support. It has been postulated that COVID-19 lung injury may share some features with those observed in hyperoxic acute lung injury. Thus, a correct target arterial oxygen tension (PaO2) during oxygen supplementation may be crucial to protect the lung from further tissue damage. The aims of this study were: 1) to evaluate the effects of conservative oxygen supplementation during helmet CPAP therapy on mortality and intensive care unit (ICU) admission in patients with COVID-19 and respiratory failure, and 2) to evaluate the effect of conservative oxygen supplementation on new-onset organ failure and secondary pulmonary infections. Methods This was a single-centre, historically controlled study of patients with severe respiratory failure due to COVID-19 pneumonia, receiving either conservative or nonconservative oxygen supplementation during helmet CPAP. A cohort receiving conservative oxygen supplementation was studied prospectively in which oxygen supplementation was administered with a target PaO2

Published
2023
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8. Cardiac involvement in consecutive unselected hospitalized COVID-19 population: In-hospital evaluation and one-year follow-up

Author

Alida, Albante, Fabio, Araimo Morselli, Daniela, Auricchio, D'Antoni, Letizia, Giovanna, Barletta, Federico, Bilotta, Matteo, Brisciani, Katia, Bruno, Clelia, Bucarelli Maria, Alessandro, Cappannoli, Giancarlo, Ceccarelli, Paola, Celli, Stella, Consolo, Giulia, Consoli, Claudia, Croce, Beatrice, Crocitti, Letizia, D'Antoni, Francesco, De Lazzaro, Daniela, De Lauri, Maria, De Rose, Andrea, Del Bianco, Valerio, Di Bella, Laura, Di Sano, Carmela, Di Santo, Santi, Francavilla, Lorena, Giannetti, Giovanni, Giordano, Stefano, Ianni, Carmela, Imperiale, Ilaria, Maestrini, Eugenia, Magnanimi, Chiara, Manganelli, Federica, Maldarelli, Sabina, Martelli, Teresa, Messina, Martina, Novelli, Patrizia, Pasculli, Fabiola, Pasqualitto, Elisa, Pattelli, Filippo, Pecorari, Serena, Perrella, Angelo, Petroianni, Mario, Piazzolla, Monica, Portieri, Silvia, Prosperi, Sebastian, Rachele Edoardo, Fabiola, Ratini, Claudia, Ricci, Hilde, Romano, Anna, Sabani, Pietro, Santopietro, Guglielmo, Tellan, Luca, Titi, Paolo, Tordiglione, Antonella, Tosi, Fausto, Trigilia, Noemi, Verduci, Paola, Vaccaro, Maestrini, Viviana, Birtolo, Lucia Ilaria, Francone, Marco, Galardo, Gioacchino, Galea, Nicola, Severino, Paolo, Alessandri, Francesco, Colaiacomo, Maria Chiara, Cundari, Giulia, Chimenti, Cristina, Lavalle, Carlo, Ciardi, Maria, Palange, Paolo, Deales, Alberto, d'Ettorre, Gabriella, Mastroianni, Claudio M., Catalano, Carlo, Ruberto, Franco, Pugliese, Francesco, d'Amati, Giulia, Fedele, Francesco, and Mancone, Massimo

Published
2021
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11. Conservative oxygen supplementation during helmet CPAP therapy in patients with COVID-19 and respiratory failure: a pilot study

Author

IACOVELLI, ALESSANDRA, primary, Nicolardi, Maria Luisa, additional, Baccolini, Valentina, additional, Olmati, Federica, additional, Attilia, Ilenia, additional, Baiocchi, Pia, additional, D’Antoni, Letizia, additional, Menichini, Ilaria, additional, Migliarini, Ambra, additional, Pellegrino, Daniela, additional, Petroianni, Angelo, additional, Piamonti, Daniel, additional, Tramontano, Angela, additional, Villari, Paolo, additional, and Palange, Paolo, additional

Published
2023
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15. Conservative oxygen supplementation during helmet continuous positive airway pressure therapy in patients with COVID-19 and respiratory failure: a pilot study

Author

Alessandra Iacovelli, Maria Luisa Nicolardi, Valentina Baccolini, Federica Olmati, Ilenia Attilia, Pia Baiocchi, Letizia D'Antoni, Ilaria Menichini, Ambra Migliarini, Daniela Pellegrino, Angelo Petroianni, Daniel Piamonti, Angela Tramontano, Paolo Villari, and Paolo Palange

Subjects
Pulmonary and Respiratory Medicine
Abstract

BackgroundRespiratory failure is a severe complication in coronavirus disease 2019 (COVID-19) pneumonia that, in addition to oxygen therapy, may require continuous positive airway pressure (CPAP) support. It has been postulated that COVID-19 lung injury may share some features with those observed in hyperoxic acute lung injury. Thus, a correct target arterial oxygen tension (PaO2) during oxygen supplementation may be crucial to protect the lung from further tissue damage. The aims of this study were: 1) to evaluate the effects of conservative oxygen supplementation during helmet CPAP therapy on mortality and intensive care unit (ICU) admission in patients with COVID-19 and respiratory failure, and 2) to evaluate the effect of conservative oxygen supplementation on new-onset organ failure and secondary pulmonary infections.MethodsThis was a single-centre, historically controlled study of patients with severe respiratory failure due to COVID-19 pneumonia, receiving either conservative or nonconservative oxygen supplementation during helmet CPAP. A cohort receiving conservative oxygen supplementation was studied prospectively in which oxygen supplementation was administered with a targetPaO2Results71 patients were included in the conservative cohort and 75 in the nonconservative cohort. Mortality rate was lower in the conservative cohort (22.5%versus62.7%; pversus37.3%; p=0.001 and 9.9%versus45.3%; pConclusionsIn patients with COVID-19 and severe respiratory failure, conservative oxygen supplementation during helmet CPAP was associated with improved survival, lower ICU admission rate and less new-onset organ failure.

Published
2022
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17. Conservative oxygen supplementation during helmet cpap therapy in patients with COVID-19 and respiratory failure. A pilot study

Author

Iacovelli, Alessandra, Nicolardi, Maria Luisa, Baccolini, Valentina, Olmati, Federica, Attilia, Ilenia, Baiocchi, Pia, D'Antoni, Letizia, Menichini, Ilaria, Migliarini, Ambra, Pellegrino, Daniela, Petroianni, Angelo, Piamonti, Daniel, Tramontano, Angela, Villari, Paolo, and Palange, Paolo

Subjects
covid-19, cpap, respiratory failure, oxygen therapy
Published
2023

18. Conservative oxygen supplementation during Helmet CPAP therapy in patients with COVID-19 and respiratory failure: A pilot study

Author

Iacovelli, Alessandra, primary, Nicolardi, Maria Luisa, additional, Baccolini, Valentina, additional, Olmati, Federica, additional, Attilia, Ilenia, additional, Baiocchi, Pia, additional, D'Antoni, Letizia, additional, Menichini, Ilaria, additional, Migliarini, Ambra, additional, Pellegrino, Daniela, additional, Petroianni, Angelo, additional, Piamonti, Daniel, additional, Tramontano, Angela, additional, Villari, Paolo, additional, and Palange, Paolo, additional

Published
2022
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24. Asma

Author

Terzano, C., Petroianni, A., Graziani, E., and Terzano, Claudio

Published
2006
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30. FOLLOW-UP OF HOSPITALIZED COVID-19 SURVIVORS: ASSESSMENT OF SHORT AND LONG-TERM CARDIOVASCULAR SEQUELAE AFTER SARS-COV-2 INFECTION

Author

Birtolo, Lucia Ilaria, primary, Silvia, Prosperi, additional, Monosilio, Sara, additional, Cimino, Sara, additional, Filomena, Domenico, additional, D'Antoni, Letizia, additional, Francavilla, Santi, additional, Francone, Marco, additional, Galea, Nicola, additional, Severino, Paolo, additional, Pasculli, Patrizia, additional, Colaiacomo, Maria Chiara, additional, Petroianni, Angelo, additional, Chimenti, Cristina, additional, Lavalle, Carlo, additional, Badagliacca, Roberto, additional, Palange, Paolo, additional, Mastroianni, Claudio Maria, additional, Catalano, Carlo, additional, Pugliese, Francesco, additional, Ciardi, Maria, additional, Maestrini, Viviana, additional, Mancone, Massimo, additional, and Fedele, Francesco, additional

Published
2022
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31. 282 Follow-up of hospitalized COVID-19 survivors: assessment of short- and long-term cardiovascular sequelae after SARS-CoV-2 infection

Author

Birtolo, Lucia Ilaria, Prosperi, Silvia, Monosilio, Sara, Cimino, Sara, Filomena, Domenico, Alfarano, Maria, Manzi, Giovanna, Neccia, Matteo, Papa, Silvia, Passarelli, Ilaria, De Persis, Francesca, Luca, Alessandra De, Mei, Mariachiara, Di Iorio, Martina, D’Antoni, Letizia, Di Pietro, Gianluca, Francavilla, Santi, Improta, Riccardo, Marcon, Serena, Mariani, Marco Valerio, Agnes, Gianluca, Piro, Agostino, Rizzo, Massimiliano, Rachele, Edoardo Sebastian, Straito, Martina, Tocci, Marco, Francone, Marco, Galea, Nicola, Severino, Paolo, Pasculli, Patrizia, Colaiacomo, Maria Chiara, Petroianni, Angelo, Chimenti, Cristina, Lavalle, Carlo, Badagliacca, Roberto, Palange, Paolo, Mastroianni, Claudio, Catalano, Carlo, Pugliese, Francesco, Ciardi, Maria, Maestrini, Viviana, Mancone, Massimo, and Fedele, Francesco

Subjects
AcademicSubjects/MED00200, Covid-19, Cardiology and Cardiovascular Medicine
Abstract

Aims Cardiovascular sequelae in COVID-19 survivors remain largely unclear and can potentially go unrecognized. Reports on follow-up focused on cardiovascular evaluation after hospital discharge are currently scarce. Aim of this prospective study was to assess cardiovascular sequelae in previously hospitalized COVID-19 survivors. Methods and results The study was conducted at ‘Sapienza’ University of Rome—Policlinico ‘Umberto I’. After 2 months from discharge, n = 230 COVID-19 survivors underwent a follow-up visit at a dedicated ‘post-COVID Outpatient Clinic’. A cardiovascular evaluation including electrocardiogram (ECG), Troponin and echocardiography was performed. Further tests were requested when clinically indicated. Medical history, symptoms, arterial-blood gas, blood tests, chest computed tomography, and treatment of both in-hospital and follow-up evaluation were recorded. A 1-year telephone follow-up was performed. A total of 36 (16%) COVID-19 survivors showed persistence or delayed onset of cardiovascular disease at 2-months follow-up visit. Persistent condition was recorded in 62% of survivors who experienced an in-hospital cardiovascular disease. Delayed cardiovascular involvement included: myocarditis, pericarditis, ventricular disfunction, new onset of systemic hypertension and arrhythmias. At 1-year telephone follow-up, 105 (45%) survivors reported persistent symptoms, with dyspnoea and fatigue being the most frequent. 60% of survivors showed persistent chest CT abnormalities and among those 28% complained of persistent cardiopulmonary symptoms at long term follow-up. Conclusions Our preliminary data showed persistent or delayed onset of cardiovascular involvement (16%) at short-term follow-up and persistent symptoms (45%) at long-term follow-up. These findings suggest the need for monitoring COVID-19 survivors.

Published
2021
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32. Noninvasive Ventilation: Education and Training. A Narrative Analysis and an International Consensus Document

Author

Karim, H, Burns, K, Ciobanu, L, El-Khatib, M, Nicolini, A, Vargas, N, Hernández-Gilsoul, T, Skoczyński, S, Falcone, V, Arnal, J, Bach, J, De Santo, L, Lucchini, A, Steier, J, Purro, A, Petroianni, A, Sassoon, C, Bambi, S, Aguiar, M, Soubani, A, Taniguchi, C, Mollica, C, Berlin, D, Piervincenzi, E, Rao, F, Luigi, F, Ferrari, R, Garuti, G, Laier-Groeneveld, G, Fiorentino, G, Ho, K, Alqahtani, J, Luján, M, Moerer, O, Resta, O, Pierucci, P, Papadakos, P, Steiner, S, Stieglitz, S, Dikmen, Y, Duan, J, Bhakta, P, Iglesias, A, Corcione, N, Caldeira, V, Karakurt, Z, Valli, G, Kondili, E, Ruggieri, M, Raposo, M, Bottino, F, Soler-González, R, Gurjar, M, Sandoval-Gutierrez, J, Jafari, B, Arroyo-Cozar, M, Noval, A, Esquinas, A, Karim, Habib Md Reazaul, Burns, Karen E A, Ciobanu, Laura D, El-Khatib, Mohamad, Nicolini, Antonello, Vargas, Nicola, Hernández-Gilsoul, Thierry, Skoczyński, Szymon, Falcone, Vito Antonio, Arnal, Jean-Michel, Bach, John, De Santo, Luca Salvatore, Lucchini, Alberto, Steier, Joerg, Purro, Andrea, Petroianni, Angelo, Sassoon, Catherine S, Bambi, Stefano, Aguiar, Margarida, Soubani, Ayman O, Taniguchi, Corinne, Mollica, Corrado, Berlin, David A, Piervincenzi, Edoardo, Rao, Fabrizio, Luigi, Ferini-Strambi, Ferrari, Rodolfo, Garuti, Giancarlo, Laier-Groeneveld, Gerhard, Fiorentino, Giuseppe, Ho, Kwok M, Alqahtani, Jaber Saud, Luján, Manuel, Moerer, Onnen, Resta, Onofrio, Pierucci, Paola, Papadakos, Peter, Steiner, Stephan, Stieglitz, Sven, Dikmen, Yalim, Duan, Jun, Bhakta, Pradipta, Iglesias, Alejandro Ubeda, Corcione, Nadia, Caldeira, Vânia, Karakurt, Zuhal, Valli, Gabriele, Kondili, Eumorfia, Ruggieri, Maria Pia, Raposo, Margarida Simões, Bottino, Fabrizio, Soler-González, Rafael, Gurjar, Mohan, Sandoval-Gutierrez, José Luis, Jafari, Behrouz, Arroyo-Cozar, Marta, Noval, Ana Roca, Esquinas, Antonio M, Karim, H, Burns, K, Ciobanu, L, El-Khatib, M, Nicolini, A, Vargas, N, Hernández-Gilsoul, T, Skoczyński, S, Falcone, V, Arnal, J, Bach, J, De Santo, L, Lucchini, A, Steier, J, Purro, A, Petroianni, A, Sassoon, C, Bambi, S, Aguiar, M, Soubani, A, Taniguchi, C, Mollica, C, Berlin, D, Piervincenzi, E, Rao, F, Luigi, F, Ferrari, R, Garuti, G, Laier-Groeneveld, G, Fiorentino, G, Ho, K, Alqahtani, J, Luján, M, Moerer, O, Resta, O, Pierucci, P, Papadakos, P, Steiner, S, Stieglitz, S, Dikmen, Y, Duan, J, Bhakta, P, Iglesias, A, Corcione, N, Caldeira, V, Karakurt, Z, Valli, G, Kondili, E, Ruggieri, M, Raposo, M, Bottino, F, Soler-González, R, Gurjar, M, Sandoval-Gutierrez, J, Jafari, B, Arroyo-Cozar, M, Noval, A, Esquinas, A, Karim, Habib Md Reazaul, Burns, Karen E A, Ciobanu, Laura D, El-Khatib, Mohamad, Nicolini, Antonello, Vargas, Nicola, Hernández-Gilsoul, Thierry, Skoczyński, Szymon, Falcone, Vito Antonio, Arnal, Jean-Michel, Bach, John, De Santo, Luca Salvatore, Lucchini, Alberto, Steier, Joerg, Purro, Andrea, Petroianni, Angelo, Sassoon, Catherine S, Bambi, Stefano, Aguiar, Margarida, Soubani, Ayman O, Taniguchi, Corinne, Mollica, Corrado, Berlin, David A, Piervincenzi, Edoardo, Rao, Fabrizio, Luigi, Ferini-Strambi, Ferrari, Rodolfo, Garuti, Giancarlo, Laier-Groeneveld, Gerhard, Fiorentino, Giuseppe, Ho, Kwok M, Alqahtani, Jaber Saud, Luján, Manuel, Moerer, Onnen, Resta, Onofrio, Pierucci, Paola, Papadakos, Peter, Steiner, Stephan, Stieglitz, Sven, Dikmen, Yalim, Duan, Jun, Bhakta, Pradipta, Iglesias, Alejandro Ubeda, Corcione, Nadia, Caldeira, Vânia, Karakurt, Zuhal, Valli, Gabriele, Kondili, Eumorfia, Ruggieri, Maria Pia, Raposo, Margarida Simões, Bottino, Fabrizio, Soler-González, Rafael, Gurjar, Mohan, Sandoval-Gutierrez, José Luis, Jafari, Behrouz, Arroyo-Cozar, Marta, Noval, Ana Roca, and Esquinas, Antonio M

Abstract

Noninvasive ventilation (NIV) is an increasingly used method of respiratory support. The use of NIV is expanding over the time and if properly applied, it can save patients’ lives and improve long-term prognosis. However, both knowledge and skills of its proper use as life support are paramount. This systematic review aimed to assess the importance of NIV education and training. Literature search was conducted (MEDLINE: 1990 to June, 2018) to identify randomized controlled studies and systematic reviews with the results analyzed by a team of experts across the world through e-mail based communications. Clinical trials examining the impact of education and training in NIV as the primary objective was not found. A few studies with indirect evidence, a simulation-based training study, and narrative reviews were identified. Currently organized training in NIV is implemented only in a few developed countries. Due to a lack of high-grade experimental evidence, an international consensus on NIV education and training based on opinions from 64 experts across the twenty-one different countries of the world was formulated. Education and training have the potential to increase knowledge and skills of the clinical staff who deliver medical care using NIV. There is a genuine need to develop structured, organized NIV education and training programs, especially for the developing countries

Published
2019

33. Noninvasive ventilation: Education and training. A narrative analysis and an international consensus document

Author

Habib Karim, Karen Burns, Laura Ciobanu, Mohamad El-Khatib, Antonello Nicolini, Nicola Vargas, Thierry Hernández-Gilsoul, Szymon Skoczyński, Vito Falcone, Jean-Michel Arnal, John Bach, Luca De Santo, Alberto Lucchini, Joerg Steier, Andrea Purro, Angelo Petroianni, Catherine Sassoon, Stefano Bambi, Margarida Aguiar, Ayman Soubani, Corinne Taniguchi, Corrado Mollica, David Berlin, Edoardo Piervincenzi, Fabrizio Rao, Ferini-Strambi Luigi, Rodolfo Ferrari, Giancarlo Garuti, Gerhard Laier-Groeneveld, Giuseppe Fiorentino, Kwok Ho, Jaber Alqahtani, Manuel Luján, Onnen Moerer, Onofrio Resta, Paola Pierucci, Peter Papadakos, Stephan Steiner, Sven Stieglitz, Yalim Dikmen, Jun Duan, Pradipta Bhakta, Alejandro Iglesias, Nadia Corcione, Vânia Caldeira, Zuhal Karakurt, Gabriele Valli, Eumorfia Kondili, Maria Ruggieri, Margarida Raposo, Fabrizio Bottino, Rafael Soler-González, Mohan Gurjar, José Sandoval-Gutierrez, Behrouz Jafari, Marta Arroyo-Cozar, Ana Noval, Igor Barjaktarevic, Irena Sarc, Bushra Mina, Zbigniew Szkulmowski, Antonio Esquinas, Reazaul Karim, H. M., Burns, K. E. A., Ciobanu, L. D., El-Khatib, M., Nicolini, A., Vargas, N., Hernandez-Gilsoul, T., Skoczynski, S., Falcone, V. A., Arnal, J. -M., Bach, J., De Santo, L. S., Lucchini, A., Steier, J., Purro, A., Petroianni, A., Sassoon, C. S., Bambi, S., Aguiar, M., Soubani, A. O., Taniguchi, C., Mollica, C., Berlin, D. A., Piervincenzi, E., Rao, F., Luigi, F. -S., Ferrari, R., Garuti, G., Laier-Groeneveld, G., Fiorentino, G., Ho, K. M., Alqahtani, J. S., Lujan, M., Moerer, O., Resta, O., Pierucci, P., Papadakos, P., Steiner, S., Stieglitz, S., Dikmen, Y., Duan, J., Bhakta, P., Iglesias, A. U., Corcione, N., Caldeira, V., Karakurt, Z., Valli, G., Kondili, E., Ruggieri, M. P., Raposo, M. S., Bottino, F., Soler-Gonzalez, R., Gurjar, M., Sandoval-Gutierrez, J. L., Jafari, B., Arroyo-Cozar, M., Noval, A. R., Barjaktarevic, I., Sarc, I., Mina, B., Szkulmowski, Z., Esquinas, A. M., Karim, H, Burns, K, Ciobanu, L, El-Khatib, M, Nicolini, A, Vargas, N, Hernández-Gilsoul, T, Skoczyński, S, Falcone, V, Arnal, J, Bach, J, De Santo, L, Lucchini, A, Steier, J, Purro, A, Petroianni, A, Sassoon, C, Bambi, S, Aguiar, M, Soubani, A, Taniguchi, C, Mollica, C, Berlin, D, Piervincenzi, E, Rao, F, Luigi, F, Ferrari, R, Garuti, G, Laier-Groeneveld, G, Fiorentino, G, Ho, K, Alqahtani, J, Luján, M, Moerer, O, Resta, O, Pierucci, P, Papadakos, P, Steiner, S, Stieglitz, S, Dikmen, Y, Duan, J, Bhakta, P, Iglesias, A, Corcione, N, Caldeira, V, Karakurt, Z, Valli, G, Kondili, E, Ruggieri, M, Raposo, M, Bottino, F, Soler-González, R, Gurjar, M, Sandoval-Gutierrez, J, Jafari, B, Arroyo-Cozar, M, Noval, A, and Esquinas, A

Subjects
Pulmonary and Respiratory Medicine, osebje, usposabljanje, Attitude of Health Personnel, education, MEDLINE, Developing country, HSM PNEU, Narrative inquiry, staff, zdravstveno osebje -- izobraževanje, Education, noninvasive ventilation -- education, Medical Staff, Hospital, Humans, Training, Narrative, health personnel -- education, udc:616.2, Respiratory Distress Syndrome, Medical education, Noninvasive Ventilation, training, Program, Staff, neinvazivna ventilacija -- izobraževanje, Pneumonia, Ventilator-Associated, 3. Good health, Clinical trial, Systematic review, Life support, Programs, Clinical Competence, Respiratory Insufficiency, Psychology, Developed country, Noninvasive ventilation
Abstract

Noninvasive ventilation (NIV) is an increasingly used method of respiratory support. The use of NIV is expanding over the time and if properly applied, it can save patients' lives and improve long-term prognosis. However, both knowledge and skills of its proper use as life support are paramount. This systematic review aimed to assess the importance of NIV education and training. Literature search was conducted (MEDLINE: 1990 to June, 2018) to identify randomized controlled studies and systematic reviews with the results analyzed by a team of experts across the world through e-mail based communications. Clinical trials examining the impact of education and training in NIV as the primary objective was not found. A few studies with indirect evidence, a simulation-based training study, and narrative reviews were identified. Currently organized training in NIV is implemented only in a few developed countries. Due to a lack of high-grade experimental evidence, an international consensus on NIV education and training based on opinions from 64 experts across the twenty-one different countries of the world was formulated. Education and training have the potential to increase knowledge and skills of the clinical staff who deliver medical care using NIV. There is a genuine need to develop structured, organized NIV education and training programs, especially for the developing countries. info:eu-repo/semantics/publishedVersion

Published
2019
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35. Cardiac involvement in consecutive unselected hospitalized COVID-19 population: In-hospital evaluation and one-year follow-up

Author

Maestrini, Viviana, primary, Birtolo, Lucia Ilaria, additional, Francone, Marco, additional, Galardo, Gioacchino, additional, Galea, Nicola, additional, Severino, Paolo, additional, Alessandri, Francesco, additional, Colaiacomo, Maria Chiara, additional, Cundari, Giulia, additional, Chimenti, Cristina, additional, Lavalle, Carlo, additional, Ciardi, Maria, additional, Palange, Paolo, additional, Deales, Alberto, additional, d'Ettorre, Gabriella, additional, Mastroianni, Claudio M., additional, Catalano, Carlo, additional, Ruberto, Franco, additional, Pugliese, Francesco, additional, d'Amati, Giulia, additional, Fedele, Francesco, additional, Mancone, Massimo, additional, Alida, Albante, additional, Fabio, Araimo Morselli, additional, Daniela, Auricchio, additional, D'Antoni, Letizia, additional, Giovanna, Barletta, additional, Federico, Bilotta, additional, Matteo, Brisciani, additional, Katia, Bruno, additional, Clelia, Bucarelli Maria, additional, Alessandro, Cappannoli, additional, Giancarlo, Ceccarelli, additional, Paola, Celli, additional, Stella, Consolo, additional, Giulia, Consoli, additional, Claudia, Croce, additional, Beatrice, Crocitti, additional, Letizia, D'Antoni, additional, Francesco, De Lazzaro, additional, Daniela, De Lauri, additional, Maria, De Rose, additional, Andrea, Del Bianco, additional, Valerio, Di Bella, additional, Laura, Di Sano, additional, Carmela, Di Santo, additional, Santi, Francavilla, additional, Lorena, Giannetti, additional, Giovanni, Giordano, additional, Stefano, Ianni, additional, Carmela, Imperiale, additional, Ilaria, Maestrini, additional, Eugenia, Magnanimi, additional, Chiara, Manganelli, additional, Federica, Maldarelli, additional, Sabina, Martelli, additional, Teresa, Messina, additional, Martina, Novelli, additional, Patrizia, Pasculli, additional, Fabiola, Pasqualitto, additional, Elisa, Pattelli, additional, Filippo, Pecorari, additional, Serena, Perrella, additional, Angelo, Petroianni, additional, Mario, Piazzolla, additional, Monica, Portieri, additional, Silvia, Prosperi, additional, Sebastian, Rachele Edoardo, additional, Fabiola, Ratini, additional, Claudia, Ricci, additional, Hilde, Romano, additional, Anna, Sabani, additional, Pietro, Santopietro, additional, Guglielmo, Tellan, additional, Luca, Titi, additional, Paolo, Tordiglione, additional, Antonella, Tosi, additional, Fausto, Trigilia, additional, Noemi, Verduci, additional, and Paola, Vaccaro, additional

Published
2021
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36. Cardiac involvement in consecutive unselected hospitalized COVID-19 population: in-hospital evaluation and one-year follow-up

Author

Bruno Katia, Nicola Galea, Barletta Giovanna, Maldarelli Federica, De Lauri Daniela, Pasqualitto Fabiola, Prosperi Silvia, Francesco Pugliese, Titi Luca, Lucia Ilaria Birtolo, Del Bianco Andrea, Albante Alida, Francesco Fedele, Cappannoli Alessandro, Imperiale Carmela, Giannetti Lorena, Gabriella d'Ettorre, Marco Francone, Messina Teresa, Claudio Maria Mastroianni, Perrella Serena, Consolo Stella, De Rose Maria, Petroianni Angelo, Magnanimi Eugenia, Romano Hilde, Celli Paola, De Lazzaro Francesco, Carlo Catalano, Giulia d'Amati, Tosi Antonella, Brisciani Matteo, Martelli Sabina, Di Bella Valerio, Maestrini Ilaria, Paolo Severino, Massimo Mancone, Alberto Deales, Piazzolla Mario, Bilotta Federico, Bucarelli Maria Clelia, Maria Chiara Colaiacomo, Ricci Claudia, Croce Claudia, Tellan Guglielmo, Gioacchino Galardo, Ceccarelli Giancarlo, Ianni Stefano, Cristina Chimenti, Novelli Martina, Pasculli Patrizia, Verduci Noemi, Tordiglione Paolo, Santopietro Pietro, Rachele Edoardo Sebastian, Araimo Morselli Fabio, Auricchio Daniela, Manganelli Chiara, Letizia D'Antoni, Ratini Fabiola, Paolo Palange, Portieri Monica, Viviana Maestrini, Giordano Giovanni, Francavilla Santi, Maria Rosa Ciardi, Di Sano Laura, Pecorari Filippo, Carlo Lavalle, Di Santo Carmela, Crocitti Beatrice, Vaccaro Paola, Franco Ruberto, Trigilia Fausto, D'Antoni Letizia, Pattelli Elisa, Consoli Giulia, Francesco Alessandri, Sabani Anna, and Giulia Cundari

Subjects
medicine.medical_specialty, education.field_of_study, COPD, business.industry, medicine.medical_treatment, Population, Percutaneous coronary intervention, 030204 cardiovascular system & hematology, medicine.disease, COVID-19, cardiovascular disease, cardiovascular magnetic resonance, echocardiography, follow-up, myocarditis, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Heart failure, medicine, Medical history, cardiovascular diseases, 030212 general & internal medicine, Myocardial infarction, Cardiology and Cardiovascular Medicine, education, Prospective cohort study, business
Abstract

Background Cardiovascular disease (CVD) can occur in COVID-19 and has impact on clinical course. Data on CVD prevalence in hospitalized COVID-19 patients and sequelae in survivors is limited. Aim of this prospective study carried out on consecutive unselected COVID-19 population, was to assess: 1) CVD occurrence among hospitalized COVID-19 patients, 2) persistence or new onset of CVD at one-month and one-year follow-up. Methods Over 30 days n = 152 COVID-19 patients underwent cardiovascular evaluation. Standard electrocardiogram (ECG), Troponin and echocardiography were integrated by further tests when indicated. Medical history, arterial blood gas, blood tests, chest computed tomography and treatment were recorded. CVD was defined as the occurrence of a new condition during the hospitalization for COVID-19. Survivors attended a one-month follow-up visit and a one-year telephone follow-up. Results Forty-two patients (28%) experienced a wide spectrum of CVD with acute myocarditis being the most frequent. Death occurred in 32 patients (21%) and more frequently in patients who developed CVD (p = 0.032). After adjustment for confounders, CVD was independently associated with death occurrence. At one-month follow-up visit, 7 patients (9%) presented persistent or delayed CVD. At one-year telephone follow-up, 57 patients (48%) reported persistent symptoms. Conclusion Cardiovascular evaluation in COVID-19 patients is crucial since the occurrence of CVD in hospitalized COVID-19 patients is common (28%), requires specific treatment and increases the risk of in-hospital mortality. Persistence or delayed presentation of CVD at 1-month (9%) and persistent symptoms at 1-year follow-up (48%) suggest the need for monitoring COVID-19 survivors.

Published
2021

40. FOLLOW-UP OF HOSPITALIZED COVID-19 SURVIVORS: ASSESSMENT OF SHORT AND LONG-TERM CARDIOVASCULAR SEQUELAE AFTER SARS-COV-2 INFECTION

Author

Lucia Ilaria Birtolo, Prosperi Silvia, Sara Monosilio, Sara Cimino, Domenico Filomena, Letizia D'Antoni, Santi Francavilla, Marco Francone, Nicola Galea, Paolo Severino, Patrizia Pasculli, Maria Chiara Colaiacomo, Angelo Petroianni, Cristina Chimenti, Carlo Lavalle, Roberto Badagliacca, Paolo Palange, Claudio Maria Mastroianni, Carlo Catalano, Francesco Pugliese, Maria Ciardi, Viviana Maestrini, Massimo Mancone, and Francesco Fedele

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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48. RESET OF PERINUCLEAR ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODIES (P-ANCA) IN PATIENT WITH SEVERE ASTHMA AND EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS (EGPA) DURING BENRALIZUMAB TREATMENT

Author

Angelo Petroianni, Paolo Palange, L. D'Antoni, E. Graziani, and P. Scarano

Subjects
Pulmonary and Respiratory Medicine, P-ANCA, biology, business.industry, Severe asthma, Critical Care and Intensive Care Medicine, Benralizumab, medicine.disease, chemistry.chemical_compound, chemistry, Immunology, Eosinophilic, biology.protein, Medicine, In patient, Antibody, Cardiology and Cardiovascular Medicine, business, Granulomatosis with polyangiitis, Neutrophil cytoplasmic
Published
2020
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50. Noninvasive Ventilation: Education and Training. A Narrative Analysis and an International Consensus Document

Author

Karim, Habib, primary, Burns, Karen, additional, Ciobanu, Laura, additional, El-Khatib, Mohamad, additional, Nicolini, Antonello, additional, Vargas, Nicola, additional, Hernández-Gilsoul, Thierry, additional, Skoczyński, Szymon, additional, Falcone, Vito, additional, Arnal, Jean-Michel, additional, Bach, John, additional, De Santo, Luca, additional, Lucchini, Alberto, additional, Steier, Joerg, additional, Purro, Andrea, additional, Petroianni, Angelo, additional, Sassoon, Catherine, additional, Bambi, Stefano, additional, Aguiar, Margarida, additional, Soubani, Ayman, additional, Taniguchi, Corinne, additional, Mollica, Corrado, additional, Berlin, David, additional, Piervincenzi, Edoardo, additional, Rao, Fabrizio, additional, Luigi, Ferini-Strambi, additional, Ferrari, Rodolfo, additional, Garuti, Giancarlo, additional, Laier-Groeneveld, Gerhard, additional, Fiorentino, Giuseppe, additional, Ho, Kwok, additional, Alqahtani, Jaber, additional, Luján, Manuel, additional, Moerer, Onnen, additional, Resta, Onofrio, additional, Pierucci, Paola, additional, Papadakos, Peter, additional, Steiner, Stephan, additional, Stieglitz, Sven, additional, Dikmen, Yalim, additional, Duan, Jun, additional, Bhakta, Pradipta, additional, Iglesias, Alejandro, additional, Corcione, Nadia, additional, Caldeira, Vânia, additional, Karakurt, Zuhal, additional, Valli, Gabriele, additional, Kondili, Eumorfia, additional, Ruggieri, Maria, additional, Raposo, Margarida, additional, Bottino, Fabrizio, additional, Soler-González, Rafael, additional, Gurjar, Mohan, additional, Sandoval-Gutierrez, José, additional, Jafari, Behrouz, additional, Arroyo-Cozar, Marta, additional, Noval, Ana, additional, Barjaktarevic, Igor, additional, Sarc, Irena, additional, Mina, Bushra, additional, Szkulmowski, Zbigniew, additional, and Esquinas, Antonio, additional

Published
2019
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