1. Signs of Residuals for Testing Coefficients in Quantile Regression
- Author
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Peter Tarassenko, Rodney Sparapani, John R. Meurer, Sergey Tarima, Bonifride Tuyishimire, and Lisa Rein
- Subjects
Variables ,Null model ,media_common.quotation_subject ,Statistics ,Linear regression ,Normality ,Mathematics ,Quantile ,Variable (mathematics) ,media_common ,Quantile regression ,Statistical hypothesis testing - Abstract
We introduce a family of tests for regression coefficients based on signs of quantile regression residuals. In our approach, we first fit a quantile regression for the model where an independent variable of interest is not included in the set of model predictors (the null model). Then signs of residuals of this null model are tested for association with the predictor of interest. This conditionally exact testing procedure is applicable for randomized studies. Further, we extend this testing procedure to observational data when co-linearity between the variable of interest and other model predictors is possible. In the presence of possible co-linearity, tests for conditional association controlling for other model predictors are used. Monte Carlo simulation studies show superior performance of the introduced tests over several other widely available testing procedures. These simulations explore situations when normality of regression coefficients is not met. An illustrative example shows the use of the proposed tests for investigating associations of hypertension with quantiles of hemoglobin A1C change.
- Published
- 2018
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