1. Predictors of seropositivity to SARS-CoV-2 among employees at a large urban medical center
- Author
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Kupferwasser, Deborah, Flores, Evelyn A, Merino, Prudencio, Tran, Donna Phan, Liu, Honghu, Huang, Yilan, Bolaris, Michael, Nguyen, Megan H, Gonzales, Mildred, Da Silva, Wellington, Astorga-Cook, Leslie, Abueg, Angel, Mason, Holli, and Miller, Loren G
- Subjects
Epidemiology ,Health Services and Systems ,Public Health ,Health Sciences ,Infectious Diseases ,Coronaviruses ,Emerging Infectious Diseases ,Coronaviruses Disparities and At-Risk Populations ,Good Health and Well Being ,Humans ,COVID-19 ,Male ,Female ,Adult ,Middle Aged ,SARS-CoV-2 ,Risk Factors ,Seroepidemiologic Studies ,Health Personnel ,Personal Protective Equipment ,Young Adult ,Antibodies ,Viral ,Surveys and Questionnaires ,Health system workforce ,Seropositivity ,Public Health and Health Services ,Health services and systems ,Public health - Abstract
BackgroundBefore SARS-CoV-2 vaccination availability, medical center employees were at high risk of COVID-19. However, risk factors for SARS-CoV-2 infection in medical center employees, both healthcare and non-healthcare workers, are poorly understood.MethodsFrom September-December 2020, free IgG antibody testing was offered to all employees at a large urban medical center. Participants were asked to complete a questionnaire on work and non-work related risk factors for COVID-19 infection.ResultsSARS-CoV-2 seropositivity was found in 4.7%. Seropositivity was associated with close contact with COVID-19 cases with or without the use of adequate personal protective equipment (PPE), (OR 3.1 [95% CI 1.4-6.9] and OR 4.7 [95% CI 2.0-11.0] respectively), never wearing a mask outside of work (OR 10.1 [95% CI 1.9-57]), and Native Hawaiian/Pacific Islander race (OR 6.3 95% CI (1.6-25)].ConclusionsAmong workers in a large urban medical center, SARS-CoV-2 seropositivity was associated with work-related COVID-19 close contacts and low mask use outside of work, suggesting that non-workplace close contacts are also relevant routes of COVID-19 spread among healthcare workers.
- Published
- 2024