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2. Indicators of Deprivation Predict Diurnal Cortisol Regulation during Infancy

Author

Perrone, Laura, Frost, Allison, Kuzava, Sierra, Nissim, Galia, Vaccaro, Suzanne, Rodriguez, Melanie, Dash, Allison, and Bernard, Kristin

Abstract

Dysregulation of diurnalcortisol rhythms is often seen among children exposed to early adversity and has been associated with a variety of negative physical and mental health outcomes. The present study examined whether two indicators of deprivation, sociodemographic burden and observed parental insensitivity, were associated with child diurnal cortisol rhythms among a diverse community sample of 250 infants ages 5 to 22 months (M = 12.68 months, 47.2% male). The sample was diverse in terms of socioeconomic status as assessed by household income (M = $59,163, SD = $57,775, range = $0-230,000) and infant race/ethnicity (41.6% African American, 19.2% White, 17.2% multiracial, 14.0% Hispanic/Latin, 2.8% Caribbean, 2.8% other, 1.2% American Indian/Alaska Native, and 1.2% Asian). Sociodemographic burden indicators were assessed through questionnaires completed by the parent. Parental sensitivity was assessed through observations of parents' interactions with their infants during a play interaction task. Cortisol was assayed from infant saliva samples collected at waking and bedtime across 3 days. Structural equation modeling revealed that higher sociodemographic burden, but not parental insensitivity, was associated with blunted diurnal cortisol slopes. Neither sociodemographic burden nor parental insensitivity were associated with the cortisol awakening response. These findings suggest that sociodemographic burden may be an important early predictor of diurnal cortisol slope dysregulation, highlighting the importance of interventions providing support to individuals who experience sociodemographic burden and promoting reduction of these early stressors.

Published
2021
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3. Adult Processing of Child Emotional Expressions: A Meta-Analysis of ERP Studies

Author

Kuzava, Sierra, Frost, Allison, Perrone, Laura, Kang, Erin, Lindhiem, Oliver, and Bernard, Kristin

Abstract

Numerous event-related potential (ERP) studies have examined adults' neural responses to child emotional expressions to understand the neurobiological mechanisms contributing to caregiving. It is unclear, however, whether one emotion evokes an enhanced response across components, and whether this pattern differs based on parent status or other sample characteristics. This meta-analysis quantified adult responses to child emotional expressions at the N170 and the late positive potential (LPP) components. Cohen's d reflected the difference between crying and neutral (CN), crying and laughing (CL), and laughing and neutral (LN) N170 and LPP amplitudes. Crying expressions elicited slightly enhanced N170 and LPP amplitudes relative to neutral and laughing expressions (N170 CN: k = 24, d = -0.09, p < 0.001; N170 CL: k = 30, d = -0.07, p = 0.004; LPP CN: k = 20, d = 0.12, p = 0.027; LPP CL: k = 27, d = 0.10, p < 0.001), and laughing expressions elicited slightly enhanced N170 amplitudes relative to neutral expressions (N170 LN: k = 21, d = -0.05, p = 0.02). Parental status, child age, risk factors for insensitive caregiving, and measurement characteristics moderated some effect sizes, with reference electrode emerging as the most consistent moderator. Results shed light on the typical pattern of neural response to child emotions and characteristics that may moderate this response.

Published
2020
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5. Not Autoimmune Diabetes Mellitus in Paediatrics

Author

Iafusco, Dario, Confetto, Santino, Zanfardino, Angela, Piscopo, Alessia, Casaburo, Francesca, Cocca, Alessandra, Caredda, Elisabetta, Pezzino, Giulia, Tinto, Nadia, Pirozzi, Daniele, Napoli, Angela, Barbetti, Fabrizio, Perrone, Laura, Scaramuzza, Andrea, editor, de Beaufort, Carine, editor, and Hanas, Ragnar, editor

Published
2017
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9. Foster Parenting

Author

Bernard, Kristin, primary, Frost, Allison, additional, Kuzava, Sierra, additional, and Perrone, Laura, additional

Published
2019
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16. Diagnosis, treatment and prevention of pediatric obesity: consensus position statement of the Italian Society for Pediatric Endocrinology and Diabetology and the Italian Society of Pediatrics

Author

Valerio, Giuliana, Maffeis, Claudio, Saggese, Giuseppe, Ambruzzi, Maria Amalia, Balsamo, Antonio, Bellone, Simonetta, Bergamini, Marcello, Bernasconi, Sergio, Bona, Gianni, Calcaterra, Valeria, Canali, Teresa, Caroli, Margherita, Chiarelli, Francesco, Corciulo, Nicola, Crinò, Antonino, Di Bonito, Procolo, Di Pietrantonio, Violetta, Di Pietro, Mario, Di Sessa, Anna, Diamanti, Antonella, Doria, Mattia, Fintini, Danilo, Franceschi, Roberto, Franzese, Adriana, Giussani, Marco, Grugni, Graziano, Iafusco, Dario, Iughetti, Lorenzo, Lamborghini, Adima, Licenziati, Maria Rosaria, Limauro, Raffaele, Maltoni, Giulio, Manco, Melania, Reggiani, Leonardo Marchesini, Marcovecchio, Loredana, Marsciani, Alberto, del Giudice, Emanuele Miraglia, Morandi, Anita, Morino, Giuseppe, Moro, Beatrice, Nobili, Valerio, Perrone, Laura, Picca, Marina, Pietrobelli, Angelo, Privitera, Francesco, Purromuto, Salvatore, Ragusa, Letizia, Ricotti, Roberta, Santamaria, Francesca, Sartori, Chiara, Stilli, Stefano, Street, Maria Elisabeth, Tanas, Rita, Trifiró, Giuliana, Umano, Giuseppina Rosaria, Vania, Andrea, Verduci, Elvira, and Zito, Eugenio

Published
2018
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17. Le basi genetiche dell’obesità

Author

Perrone, Laura, Raimondo, Paolo, Santoro, Nicola, del Giudice, Emanuele Miraglia, Giovannini, Marcello, editor, Maffeis, Claudio, editor, Molinari, Enrico, editor, and Scaglioni, Silvia, editor

Published
2006
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19. Efficacy and safety of growth hormone treatment in children with short stature: the Italian cohort of the GeNeSIS clinical study

Author

Cappa, M., Iughetti, L., Loche, S., Maghnie, M., Vottero, A., Antoniazzi, Franco, Beccaria, Luciano, Bernasconi, Sergio, Caggiano, Domenico, Caruso-Nicoletti, Manuela, Catucci, Alessandra, Chiarelli, Francesco, Cianfarani, Stefano, Colucci, Anna Rita, De Rienzo, Francesca, Di Pumpo, Raffaele, Di Stasio, Alessandra, Farello, Giovanni, Felici, Leonardo, Femiano, Pasquale, Garagantini, Luigi, Giavoli, Claudia, Greggio, Nella Augusta, Guazzarotti, Laura, Larizza, Daniela, Licenziati, Maria Rosaria, Lonero, Antonella, Maggio, Maria Cristina, Marsciani, Alberto, Matarazzo, Patrizia, Mazzanti, Laura, Messini, Beatrice, Napoli, Flavia, Pasquino, Anna Maria, Perrone, Laura, Pilia, Sabrina, Pilotta, Alba, Piran, Marzia, Pozzobon, Gabriella, Predieri, Barbara, Sacco, Michele, Salerno, Mariacarolina, Tirendi, Antonina, Ubertini, Graziamaria, Vannelli, Silvia, Wasniewska, Malgorzata, Zampolli, Maria, Zanotti, Martina, Zuccotti, Gianvincenzo, and GeNeSIS National Board on behalf of the GeNeSIS Italian Investigators

Published
2016
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26. Not Autoimmune Diabetes Mellitus in Paediatrics

Author

Iafusco, Dario, primary, Confetto, Santino, additional, Zanfardino, Angela, additional, Piscopo, Alessia, additional, Casaburo, Francesca, additional, Cocca, Alessandra, additional, Caredda, Elisabetta, additional, Pezzino, Giulia, additional, Tinto, Nadia, additional, Pirozzi, Daniele, additional, Napoli, Angela, additional, Barbetti, Fabrizio, additional, and Perrone, Laura, additional

Published
2016
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35. Ecological Predictors of Parental Beliefs about Infant Crying in a Randomized Clinical Trial of ABC.

Author

Thorpe, Daneele, Silver, Jamilah, Perrone, Laura, DeSantis, Nicole, Dash, Allison, Rodriguez, Melanie, Beras-Monticciolo, Erasma, and Bernard, Kristin

Subjects
ECOLOGICAL systems theory, CLINICAL trials, ATTACHMENT theory (Psychology), INFANTS, CRYING
Abstract

Attachment theory suggests that parent responsiveness to infant distress predicts secure parent–child attachment and subsequent healthy child development. While much is known about microsystem factors that interfere with responsive caregiving, there is a paucity of research investigating how exosystem factors, such as neighborhood crime, affect parenting. In a sample of 200 diverse caregivers and their 5- to 21-month-old infants (M = 11.82; 49% male), we leveraged data from a randomized clinical trial of Attachment and Biobehavioral Catch-up (ABC), an attachment-based intervention, to assess whether individual level burden (indicated by single-parent status, low income, residential instability, young parenthood, parental psychopathology, and own history of early adversity) and neighborhood crime density (geocoded within a 500 ft radius of parent's residence) were associated with their beliefs about infant crying, an indicator of responsive parenting. Consistent with Bronfenbrenner's ecological systems' theory of development, both greater exposure to individual burden indicators and greater neighborhood crime density predicted greater maladaptive beliefs about infant crying, suggesting that contextual factors outside the household are associated with parenting cognitions. Further, when accounting for the effect of crime and individual burden on parental beliefs about infant crying, participation in the ABC intervention was effective in reducing maladaptive parenting beliefs. We consider implications for multi-level intervention approaches that target family processes, neighborhood-level factors, and policy initiatives to promote community wellbeing and positive child development. [ABSTRACT FROM AUTHOR]

Published
2022
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36. Il ne bis in idem in Europa e il Double Jeopardy negli USA: una comparazione

Author

Perrone, Laura

Subjects
Ne bis in idem. Double Jeopardy. Doppi binari sanzionatori, Settore IUS/17 - Diritto Penale
Abstract

Il ne bis in idem: dal diritto romano ai nostri giorni. Il ne bis in idem interno. Il ne bis in idem europeo e i riflessi sugli ordinamenti interni. Il Double Jeopardy principle nei sistemi di Common law: l?ordinamento statunitense. Il background statunitense e i possibili strumenti a favore della compatibilit� dei cumuli sanzionatori con il ne bis in idem.

Published
2020
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41. Familial trisomy 6p in mother and daughter

Author

Savarese, Marco, Grandone, Anna, Perone, Lucia, Blanco, Francesca Del Vecchio, De Luca, Giuseppina, Di Fruscio, Giuseppina, Fogu, Giuseppina, Piluso, Giulio, Perrone, Laura, del Giudice, Emanuele Miraglia, and Nigro, Vincenzo

Published
2013
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45. Micturition Syncope in Childhood

Author

Marzuillo, Pierluigi, Guarino, Stefano, Tipo, Vincenzo, Apicella, Andrea, Grandone, Anna, Diplomatico, Mario, Polito, Cesare, Miraglia del Giudice, Emanuele, La Manna, Angela, Perrone, Laura, Marzuillo, Pierluigi, Guarino, Stefano, Tipo, Vincenzo, Apicella, Andrea, Grandone, Anna, Diplomatico, Mario, Polito, Cesare, Miraglia del Giudice, Emanuele, La Manna, Angela, and Perrone, Laura

Published
2019

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