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1. Increased viral replication in Simian immunodeficiency virus/Simian-HIV-infected Macaques with self-administering model of chronic alcohol consumption

Author

Kumar, Rakesh, Perez-Casanova, Antonio, Kumar, Anil, Tirado, Grissell, Yamamura, Yasuhiro, Higley, J. Dee, Noel, Richard J., Staprans, Silvija, Kraiselburd, Edmundo, Torres, Cynthia, Rodriguez, Idia, and Matinez, Melween

Subjects
Alcoholism -- Risk factors, Polymerase chain reaction -- Research, Simian immunodeficiency virus -- Risk factors, Simian immunodeficiency virus -- Diagnosis, Simian immunodeficiency virus -- Research, Health
Abstract

A study on the precise effect of alcohol addiction on HIV pathogenesis is designed to determine the effect of alcohol dependence on virus replication and CD4 profiles in simian immunodeficiency virus/simian-HIV-infected rhesus macaques. The extent of CD4 cell loss in the alcohol group is significantly higher than in the control animals at week 1 after infection.

Published
2005

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