78 results on '"Pereira X"'
Search Results
2. Robotic versus open lateral abdominal hernia repair: a multicenter propensity score matched analysis of perioperative and 1-year outcomes
- Author
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Pereira, X., Lima, D. L., Huang, L.-C., Salas-Parra, R., Shah, P., Malcher, F., and Sreeramoju, P.
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- 2023
- Full Text
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3. A comparison of outcomes between class-II and class-III obese patients undergoing robotic ventral hernia repair: a multicenter study
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Kudsi, O. Y., Gokcal, F., Bou-Ayash, N., Watters, E., Pereira, X., Lima, D. L., and Malcher, F.
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- 2022
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4. CURRENT ROLE AND OUTCOMES OF BARBED SUTURES IN FASCIAL CLOSURE OF VENTRAL HERNIA REPAIR: A MULTICENTER STUDY USING THE ABDOMINAL CORE HEALTH QUALITY COLLABORATIVE DATABASE
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Arias-Espinosa, L, primary, Wang, A, additional, Wermelinger, J W, additional, Olson, M, additional, Phillips, S, additional, Pereira, X, additional, Damani, T, additional, and Malcher, F, additional
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- 2024
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5. Where are the hernias? A paradoxical decrease in emergency hernia surgery during COVID-19 pandemic
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Lima, D. L., Pereira, X., dos Santos, D. C., Camacho, D., and Malcher, F.
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- 2020
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6. IMPLANTAÇÃO DA AVALIAÇÃO ERGONÔMICA DOS RISCOS DE LESÕES DE TRABALHO ATRAVÉS DO CHECKLIST DE COUTO: UMA ANÁLISE NO PROCESSO DE EXPEDIÇÃO DE UM LATICÍNIO
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Moreira, Juan Pablo Silva, primary, Leonel, Henrique Pereira x, additional, Leão, Daniel Gonçalves, additional, Marinho, Brener Gonçalves, additional, Machado, Vítor Augusto Reis, additional, Silva, Adriel Augusto dos Santos, additional, and Lopes, Célio Adriano, additional
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- 2018
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7. Robotic versus open lateral abdominal hernia repair: a multicenter propensity score matched analysis of perioperative and 1-year outcomes
- Author
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Pereira, X., primary, Lima, D. L., additional, Huang, L.-C., additional, Salas-Parra, R., additional, Shah, P., additional, Malcher, F., additional, and Sreeramoju, P., additional
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- 2022
- Full Text
- View/download PDF
8. SP4-24 Self-reported tobacco smoking practices among medical students and their perceptions towards training about tobacco smoking in medical curricula: a cross-sectional, questionnaire survey in Malaysia, India, Pakistan, Nepal, and Bangladesh
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Sreeramareddy, C, Suri, S, Menezes, R G, Kumar, H N Harsha, Rehman, M, Islam, R, Shah, M, Sathian, B, Pereira, X V, Shetty, U, and Vaswani, V R
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- 2011
- Full Text
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9. Laparoscopic hepatectomy for hepatocellular carcinoma: A study on the adoption at a large academic center
- Author
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Pereira, X., primary, Mandujano, C.C., additional, Romero-Velez, G., additional, Bellemare, S., additional, Kinkhabwala, M., additional, and Rocca, J.P., additional
- Published
- 2020
- Full Text
- View/download PDF
10. Diseño, simulación y validación por elementos finitos de sistemas flexure para aplicaciones micro-robóticas
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Angulo-Elizari, E. (Enrique), Celigüeta-Lizarza, J.T. (Juan Tomás), and Justo Pereira, X.(Xabier)
- Abstract
El documento aquí presentado corresponde a la memoria de un proyecto realizado durante el primer semestre del año 2017 en el Centro de Estudios e Investigaciones Técnicas de Guipúzcoa bajo la dirección de Juan Tomás Celigüeta. El proyecto busca otorgar el título de ingeniero mecánico a Enrique Angulo Elizari, graduado por la Escuela de Ingenieros de la Universidad de Navarra, TECNUN, en el grado de ingeniería mecánica. Hoy en día, las aplicaciones tecnológicas buscan la miniaturización de los productos de forma que sean más manejables. Dicha necesidad lleva a la tecnología a crear nuevas maneras de trabajar, dando lugar así a la micro-robótica. Este desarrollo de nuevas tecnologías ha facilitado muchos procesos. A pesar de esto, el reto está en producirlos a un coste económico. Las aplicaciones son variadas, desde el sector de la automoción hasta la biomedicina, donde está siendo imprescindible su desarrollo. El proyecto se basa en el diseño y validación de unos sistemas flexibles para aplicaciones micro-robóticas, centradas en el mundo clínico. El proyecto consiste en diseñar un sistema de varios grados de libertad que permita realizar movimientos, principalmente giros, del orden micro y nano. Para esto es imprescindible la geometría y los materiales usados. El proyecto tiene tres fases principales: el análisis de sistemas ya existentes sometidos a esfuerzos comparados con sus modelos matemáticos teóricos, el diseño de nuevos sistemas y su validación por métodos numéricos usando programas de simulación por elementos finitos. En una cuarta fase, se estudiará la posibilidad de medir experimentalmente los resultados obtenidos anteriormente mediante un sistema de galgas extensiométricas. Además, se estudiarán sus técnicas de fabricación. En este documento están desarrolladas las tres primeras partes del proyecto total. The following document corresponds to the report of a project carried out during the first semester of the year 2017 in the Centre of Studies and Technical Research of Guipúzcoa under the guidance of Juan Tomás Celigüeta. The project seeks to award the title of mechanical engineer to Enrique Angulo Elizari, graduated by the School of Engineers of the University of Navarra, TECNUN, with mechanical engineering bachelor. Nowadays, the technology seeks the miniaturization of the products in order to make them more portable and more manageable. This necessity urges to the technology to develop new working methods, thus giving rise to micro-robotics. This development has provided advantages to many processes. Besides this, the challenge is to produce them at an economic cost. The applications are multiple, from the automotive uses until biomedicine, where its development is being essential. The project is based on the design and validation of some flexure systems with micro-robotics applications, focused on medical uses. The project consists on the design a system of several degrees of freedom, which allows to produce movements, mainly rotations, measuring in micro and nano orders. For that is essential the geometry and materials used. The project has three phases: the analysis of some commercial systems submitted to efforts and comparing with their theoretical mathematical models, the design of new systems and their validation with numeric methods using finite elements simulation programs. In a fourth phase, the project will study the availability of measuring, experimentally, with strain gauges the results obtained in the simulations. Moreover, the project will study the fabrication methodologies available for those systems. In this report the three first phases of the whole project are described.
- Published
- 2019
11. Proceso de fabricación y sistema de medición de sistemas flexure para aplicaciones micro-robóticas
- Author
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Angulo-Elizari, E. (Enrique), Celigüeta-Lizarza, J.T. (Juan Tomás), and Justo Pereira, X.(Xabier)
- Abstract
El documento aquí presentado corresponde a la memoria de un proyecto realizado durante el primer semestre del año 2017 en el Centro de Estudios e Investigaciones Técnicas de Guipúzcoa bajo la dirección de Juan Tomás Celigüeta. El proyecto busca otorgar el título de ingeniero mecánico a Enrique Angulo Elizari, graduado por la Escuela de Ingenieros de la Universidad de Navarra, TECNUN, en el grado de ingeniería mecánica. Hoy en día, las aplicaciones tecnológicas buscan la miniaturización de los productos de forma que sean más manejables. Dicha necesidad lleva a la tecnología a crear nuevas maneras de trabajar, dando lugar así a la micro-robótica. Este desarrollo de nuevas tecnologías ha facilitado muchos procesos. A pesar de esto, el reto está en producirlos a un coste económico. Las aplicaciones son variadas, desde el sector de la automoción hasta la biomedicina, donde está siendo imprescindible su desarrollo. El proyecto se basa en el diseño y validación de unos sistemas flexibles para aplicaciones micro-robóticas, centradas en el mundo clínico. El proyecto consiste en diseñar un sistema de varios grados de libertad que permita realizar movimientos, principalmente giros, del orden micro y nano. Para esto es imprescindible la geometría y los materiales usados. El proyecto tiene tres fases primarias: el análisis de sistemas ya existentes sometidos a esfuerzos comparados con sus modelos matemáticos teóricos, el diseño de nuevos sistemas y su validación por métodos numéricos usando programas de simulación por elementos finitos. En una cuarta fase, se estudiará la posibilidad de medir experimentalmente los resultados obtenidos anteriormente mediante un sistema de galgas extensiométricas. Además, se estudiarán sus técnicas de fabricación. Este documento desarrolla la cuarta y quinta fase del proyecto que consisten en los procesos de fabricación y el sistema de medida que se va a instalar en las piezas. Se presentan diversas metodologías de fabricación y sobre estas se realiza una propuesta para los sistemas tratados en este proyecto. Con la parte de medición, se va a proponer una instalación para cada uno de los sistemas bajo la misma metodología de galgas extensiométricas. The following document corresponds to the report of a project carried out during the first semester of the year 2017 in the Centre of Studies and Technical Research of Guipúzcoa under the guidance of Juan Tomás Celigüeta. The project seeks to award the title of mechanical engineer to Enrique Angulo Elizari, graduated by the School of Engineers of the University of Navarra, TECNUN, with mechanical engineering bachelor. Nowadays, the technology seeks the miniaturization of the products in order to make them more portable and more manageable. This necessity urges to the technology to develop new working methods, thus giving rise to micro-robotics. This development has provided advantages to many processes. Besides this, the challenge is to produce them at an economic cost. The applications are multiple, from the automotive uses until biomedicine, where its development is being essential. The project is based on the design and validation of some flexure systems with micro-robotics applications, focused on medical uses. The project consists on the design a system of several degrees of freedom, which allows to produce movements, mainly rotations, measuring in micro and nano orders. For that is essential the geometry and materials used. The project has three phases: the analysis of some commercial systems submitted to efforts and comparing with their theoretical mathematical models, the design of new systems and their validation with numeric methods using finite elements simulation programs. In a fourth phase, the project will study the availability of measuring, experimentally, with strain gauges the results obtained in the simulations. Moreover, the project will study the fabrication methodologies available for those systems. In this report the fourth and fifth phases are described. This are the fabrication processes and the measurement system which is going to be installed in the systems. First, some fabrication processes are presented and taking account all of them, one proposal will be done for the systems developed. According to the measurement system, there will be a different proposal for each system but all of them under strain gauges bases.
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- 2017
12. Processos e problemas na urbanização da América Latina: teoria e história
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Pereira X. P. C., Paulo Cesar, primary
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- 2016
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13. INVESTORS IN PEOPLE, A STRATEGY TO IMPROVE EXISTING GOOD PRACTICE.
- Author
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Nadarajah, V. D., Yusoff, N., Ogle, J. J., and Pereira, X.
- Published
- 2003
14. Interpersonal Psychotherapy for Depression in the Ageing - A Case Study.
- Author
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Pereira, X. V.
- Subjects
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INTERPERSONAL psychotherapy , *CASE studies , *PSYCHOTHERAPY , *MENTAL health , *MENTAL illness - Abstract
Introduction: Depression is becoming increasingly prevalent as a mental health disorder worldwide. The prevalence of clinical depression is between about five and fifteen percent globally. Clinical depression has also increased in prevalence among the ageing. Some of the etiological factors associated with depression in the ageing include grief and loss, and role transitions. Interpersonal Psychotherapy (IPT), an evidenced based psychotherapy for clinical depression, has been proven to be effective for depression in the ageing. IPT addresses four main problem areas, namely - interpersonal disputes, grief and loss, role transitions and interpersonal sensitivity. The adaptation of IPT for the ageing is IPT for late-life depression or IPT - LLM which was utilized to treat the patient discussed in this case study. Methods: The patient was treated with 12 sessions of psychotherapy which is often the minimum number of sessions required in the treatment of depression with IPT. The initial sessions included the development of an Interpersonal Formulation and Interpersonal Inventory. Her problem areas were grief as her husband had passed away recently, and role transitions. The problem areas were addressed during the 8 middle IPT sessions. The final two sessions were utilized to conclude IPT treatment. Results: The patient was assessed to have a PHQ - 9 (Patient Health Questionnaire--9) score of 17 before treatment with IPT, indicating moderate depression. Her PHQ - 9 score after 12 sessions of IPT was 4 indicating minimal depression. Conclusion: This case study highlights that some of the factors that contribute to depression in the ageing are grief and role transitions, and that IPT is efficacious in the treatment of depression in the ageing. [ABSTRACT FROM AUTHOR]
- Published
- 2019
15. Transfer reactions induced with 56Ni: Shell gaps and NP pairing
- Author
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Georgiadou, A., Assié, M., Blumenfeld, Y., Le Crom, B., Guillot, J., Flavigny, F., Achouri, L., Aouadi, M., Bastin, B., Benitez, A., Borcea, R., Catford, W., Clement, E., Corsi, A., Defrance, G., Delattre, M. -C, Delaunay, F., Séréville, N., Deshayes, Q., Fernandez, B., Fisichella, M., Franchoo, S., Gibelin, J., Gillibert, A., Hammache, F., Kamalou, O., Knapton, A., Lapoux, V., Leblond, S., Marques, M., Matta, A., Morfouace, P., Orr, N., Pancin, J., Pereira, X., Perrot, L., Pollacco, E., Ramos, D., Roger, T., Rotaru, F., Scarpaci, J. -A, Sénoville, M., Sorlin, O., Stanoiu, M., Stefan, I., Suzuki, D., Jean-Charles THOMAS, Vandebrouck, M., and Verde, G.
16. Transfer reactions induced with $^{56}$Ni: shell gaps and np pairing
- Author
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Georgiadou, A., Assié, M., Blumenfeld, Y., Le Crom, B., Guillot, J., Flavigny, F., Achouri, L., Aouadi, M., Bastin, B., Benitez, A., Borcea, R., Catford, W., Clement, E., Corsi, A., Defrance, G., Delattre, M-C, Delaunay, F., Séréville, N., Deshayes, Q., Fernandez, B., Fisichella, M., Franchoo, S., Gibelin, J., Gillibert, A., Hammache, F., Kamalou, O., Knapton, A., Lapoux, V., Leblond, S., Marques, M., Matta, A., Morfouace, P., Orr, N., Pancin, J., Pereira, X., Perrot, L., Pollacco, E., Ramos, D., Roger, T., Rotaru, F., Scarpaci, J-A, Matthieu Sénoville, Sorlin, O., Stanoiu, M., Stefan, I., Suzuki, D., Thomas, J-C, Vandebrouck, M., Verde, G., Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Grand Accélérateur National d'Ions Lourds (GANIL), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Département de Physique Nucléaire (ex SPhN) (DPHN), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Normandie Université (NU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
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Pairing ,Transfer reaction ,Nuclear structure ,[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex] ,Nuclear Experiment - Abstract
International audience; The structure of the unstable doubly magic nucleus $^{56}$Ni has been investigated by measuring one-and two-nucleon transfer reactions. The radioactive beam of $^{56}$Ni was produced at GANIL-Caen, France at 30 MeV/u by means of the LISE spectrometer. The experimental setup used consists of the TIARA-MUST2-EXOGAM combination which provides an almost 4$\pi$ coverage and the ability to perform particle-$\gamma$ coincidences. To probe the N=28 gap, we studied the spectroscopy of $^{55}$Ni through one-nucleon transfer reactions on $^{56}$Ni. The excitation energy spectrum is deduced by measuring the light ejec-tiles only, while particle-$\gamma$ coincidences are used to improve the resolution of the populated states and select the main ones. Comparison between the extracted angular distributions and DWBA calculations allows the extraction of the spectroscopic strength of the hole-and particle-states populated by these one neutron pickup reactions.
17. Self-reported tobacco smoking practices among medical students and their perceptions towards training about tobacco smoking in medical curricula: A cross-sectional, questionnaire survey in Malaysia, India, Pakistan, Nepal, and Bangladesh
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Shah Mohsin, Pereira Xavier V, Islam Md R, Rahman Mahbubur, Kumar HN Harsha, Menezes Ritesh G, Suri Sushil, Sreeramareddy Chandrashekhar T, Sathian Brijesh, Shetty Ullasa, and Vaswani Vina R
- Subjects
Public aspects of medicine ,RA1-1270 ,Social pathology. Social and public welfare. Criminology ,HV1-9960 - Abstract
Abstract Background Tobacco smoking issues in developing countries are usually taught non-systematically as and when the topic arose. The World Health Organisation and Global Health Professional Student Survey (GHPSS) have suggested introducing a separate integrated tobacco module into medical school curricula. Our aim was to assess medical students' tobacco smoking habits, their practices towards patients' smoking habits and attitude towards teaching about smoking in medical schools. Methods A cross-sectional questionnaire survey was carried out among final year undergraduate medical students in Malaysia, India, Nepal, Pakistan, and Bangladesh. An anonymous, self-administered questionnaire included items on demographic information, students' current practices about patients' tobacco smoking habits, their perception towards tobacco education in medical schools on a five point Likert scale. Questions about tobacco smoking habits were adapted from GHPSS questionnaire. An 'ever smoker' was defined as one who had smoked during lifetime, even if had tried a few puffs once or twice. 'Current smoker' was defined as those who had smoked tobacco product on one or more days in the preceding month of the survey. Descriptive statistics were calculated. Results Overall response rate was 81.6% (922/1130). Median age was 22 years while 50.7% were males and 48.2% were females. The overall prevalence of 'ever smokers' and 'current smokers' was 31.7% and 13.1% respectively. A majority (> 80%) of students asked the patients about their smoking habits during clinical postings/clerkships. Only a third of them did counselling, and assessed the patients' willingness to quit. Majority of the students agreed about doctors' role in tobacco control as being role models, competence in smoking cessation methods, counseling, and the need for training about tobacco cessation in medical schools. About 50% agreed that current curriculum teaches about tobacco smoking but not systematically and should be included as a separate module. Majority of the students indicated that topics about health effects, nicotine addiction and its treatment, counselling, prevention of relapse were important or very important in training about tobacco smoking. Conclusion Medical educators should consider revising medical curricula to improve training about tobacco smoking cessation in medical schools. Our results should be supported by surveys from other medical schools in developing countries of Asia.
- Published
- 2010
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18. Implementation and finite-element analysis of shell elements confined by Through-The-Thickness uniaxial devices
- Author
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SESSA, SALVATORE, ROSATI, LUCIANO, Serpieri, Roberto, Salvatore Sessa, Roberto Serpieri, Luciano Rosati, H. Varum, J. M. Castro, L. Macedo, N. Pereira, X. Romao, G. Monti, Sessa, Salvatore, Serpieri, Roberto, and Rosati, Luciano
- Subjects
OpenSees, Shell, Through-the-Thickness, Confinement, Jacketing - Abstract
This contribution presents the implementation in OpenSees of an integration procedure based on a recently developed theory concerning stress integration along the chords of a shell element reinforced with uniaxial transverse links. Such a model has been developed in order to account for transverse confinement effects induced by through-the-thickness jacketing of masonry and reinforced concrete existing structures. In particular, transverse confinement induces a triaxial stress state in the core material of the shell increasing the stress spherical part and resulting in strength and ductility increments. In order to perform structural analyses with reduced computational costs, the presented tool permits to compute the response of plane elements confined by uniaxial devices. To this end, the implemented object accounts for the mutual interaction of uniaxial reinforcements with a triaxial core by means of equilibrium and compatibility equations involving several object classes of the OpenSees framework. Integration of the triaxial stress state along the thickness of a shell element is therefore performed by numerically solving the equilibrium/compatibility equation system. The adopted implementation strategy is summarized and modeling features are discussed. In conclusion, numerical examples show some possible applications of the proposed tool in common structural design practices.
- Published
- 2017
19. Alpine jades : from scientific analysis to Neolithic know-how
- Author
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Pierre Petrequin, Anne- Marie Pétrequin, Estelle GAUTHIER, Alison Sheridan, Maison des Sciences de l'Homme et de l'Environnement Claude Nicolas Ledoux ( MSHE ), Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), National Museums of Scotland, T. Pereira, X. Terradas and N. Bicho, ANR-12-BSH3-0005,JADE 2,Interprétations sociales des objets-signes en jades alpins dans l'Europe néolithique ( 2012 ), Maison des Sciences de l'Homme et de l'Environnement Claude Nicolas Ledoux (UAR 3124) (MSHE), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), ANR-12-BSH3-0005,JADE 2,Interprétations sociales des objets-signes en jades alpins dans l'Europe néolithique(2012), and Maison des Sciences de l'Homme et de l'Environnement Claude Nicolas Ledoux (MSHE)
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[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,[ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistory ,Alpine jade axeheads ,Neolithic ,ComputingMilieux_MISCELLANEOUS ,know-how - Abstract
International audience
- Published
- 2017
20. Elective complex ventral hernia repair in contaminated fields: A propensity score-matched analysis of long-term quality of life and outcomes between different prostheses.
- Author
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Rodriguez-Quintero JH, Estrada A, Arias-Espinosa L, Jindani R, Huang LC, Pereira X, Sreeramoju P, and Malcher F
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- Humans, Male, Middle Aged, Female, Aged, Pain, Postoperative etiology, Pain, Postoperative diagnosis, Treatment Outcome, Retrospective Studies, Patient Reported Outcome Measures, Surgical Wound Infection etiology, Surgical Wound Infection epidemiology, Hernia, Ventral surgery, Quality of Life, Herniorrhaphy adverse effects, Herniorrhaphy instrumentation, Herniorrhaphy methods, Propensity Score, Surgical Mesh, Elective Surgical Procedures adverse effects
- Abstract
Background: Randomized studies have endorsed nonabsorbable prosthetics for contaminated ventral hernia surgery, yet the broader applicability and impact on patient-reported outcomes are still questioned. Here, we evaluated the long-term outcomes of elective contaminated ventral hernia repairs (based on Centers of Disease Control and Prevention [CDC] wound classification) using real-world data from a multicenter US cohort, focusing on quality of life and postoperative pain., Methods: The Abdominal Core Health Quality Collaborative database was queried for patients undergoing elective contaminated (CDC class II-IV) ventral hernia repair (2013-2023). After propensity matching, we compared long-term differences in patient-reported quality of life and pain scores (by HerQLes and PROMIS questionnaires) among those who underwent repair with nonabsorbable, absorbable synthetic, and biologic mesh., Results: A total of 1,073 patients were included, of whom 920 (86%), 56 (5%), and 97 (9%) underwent repair with nonabsorbable, absorbable synthetic, and biologic mesh, respectively. Among them, the median age was 62 years (interquartile range [IQR] 53-70), and 523 (49%) were male. The median length and width of the defect were 20 cm (IQR 12-25) and 13 cm (IQR 8-16), respectively. A transversus abdominis release was performed in 716 patients (67% of all cases). In most cases, the mesh was positioned in the retro-rectus (85%) and/or the preperitoneal space (45%). Before and after propensity matching (n = 185), the change from baseline in HerQLes and PROMIS scores at 6 months and at 1, 3, 5, and 6 years was comparable between different types of mesh. Lastly, there were no differences in readmission, surgical site infection, or surgical site occurrence at 30 days. Recurrence at 1 year was also comparable among groups., Conclusion: In the long term, there were no differences in quality of life or pain scores with nonabsorbable, absorbable synthetic, or biologic mesh for elective ventral hernia repair in contaminated fields., Competing Interests: Conflict of Interest/Disclosure FM receives consultant fees from Intuitive, Medtronic, BD, Integra, Allergan, and DeepBlue. The rest of the authors have no financial disclosures to declare., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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21. Single-dock Robotic Bilateral Transversus Abdominis Release: Technique Description and Preliminary Outcomes.
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Estrada A, Rodriguez-Quintero JH, Arias-Espinosa L, Sreeramoju P, Cheema F, Pereira X, and Malcher F
- Abstract
Background: Posterior component separation with transversus abdominis release (TAR) is a valuable adjunct to address incisional hernia defects. Currently, bilateral docking is a standard technique for robotic TAR. The aim of this study is to describe our technique for extended totally extraperitoneal (eTEP) repair with bilateral TAR through a bottom single-dock robotic approach for hernias at the level of the umbilicus or higher., Materials and Methods: We retrospectively reviewed a case series of patients who underwent robotic eTEP repair with bilateral TAR using a single bottom docking between November 2021 and November 2023. A comprehensive description of our patient selection, surgical technique, and short-term clinical outcomes is reported., Results: Ten patients with incisional hernias were included. Their median age was 55 years (IQR: 49.5 to 61.25), 70% were male, the median BMI was 27.25 kg/m (IQR: 22.95 to 33.53), and ASA class was ≥2 in 80%. Median hernia width was 10 cm (IQR: 6.75 to 12.25) and length 11 cm (IQR: 9.25 to 16.25). The median operative time was 178.5 minutes (IQR: 153.75 to 222), and the length of stay was 1 day (IQR: 0.75 to 1.75). At a median follow-up of 5 months (IQR: 2.6 to 9.7), 20% of patients developed a surgical site occurrence requiring procedural intervention., Conclusion: Bilateral TAR using a single bottom dock is a feasible and safe adjunct to robotic eTEP ventral hernia repair in appropriately selected patients., Competing Interests: F.M. discloses consulting fees from BD, Intuitive, Integra, DeepBlue, Allergan, and Medtronic, outside the submitted study. The remaining authors declare no conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2024
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22. The current role of barbed sutures in fascial closure of ventral hernia repair: a multicenter study using the abdominal core health quality collaborative database.
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Arias-Espinosa L, Wang A, Wermelinger JP, Olson MA, Phillips S, Xie W, de Pena Pena X, Pereira X, Damani T, and Malcher F
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- Humans, Male, Female, Middle Aged, Retrospective Studies, Aged, Fasciotomy methods, Quality of Life, Databases, Factual, Adult, Patient Reported Outcome Measures, Hernia, Ventral surgery, Herniorrhaphy methods, Sutures, Suture Techniques
- Abstract
Background: Barbed sutures (BS) have been increasingly used in the last two decades across surgical disciplines but little is known about how widespread their adoption has been in ventral hernia repair (VHR). The aim of this study was to document the use of barbed sutures in VHR in a multicenter database with associated clinical and patient-reported outcomes., Method: Prospectively collected data from the Abdominal Core Health Quality Collaborative database was retrospectively reviewed, including all adult patients who underwent VHR with fascial closure from 2020 to 2022. A univariate analysis compared patients with BS against non-barbed sutures (NBS) across the preoperative, intraoperative, and postoperative timeframes including patient-reported outcomes concerning quality of life and pain scores., Results: A total of 4054 patients that underwent ventral hernia repair with BS were compared with 6473 patients with non-barbed sutures (NBS). Overall, BS were used in 86.2% of minimally invasive ventral hernia repairs and about 92.2% of robotic surgery compared to only 9.6% of open procedures. Notable differences existed in patient selection, including a higher BMI (32 vs 30.5; p < 0.001), more incisional hernias (63.3% vs 51.1%; p < 0.001), wider hernias (4 cm vs 3 cm; p < 0.001), and higher ASA score (p < 0.001) in patients with BS. Outcomes in patients with BS included a shorter length of stay (mean days; 1.4 vs 2.4; p < 0.001), less SSI (1.5% vs 3.6%; p < 0.001), while having similar SSO (7.6% vs 7.3%; p = 0.657), readmission (3.0 vs 3.2; p = 0.691), and reoperation (1.5% vs 1.45%; p = 0.855), at a longer operative time (p < 0.001). Hernia-specific questionnaires for quality of life (HerQLes) and pain in patients with BS had a worse preoperative score that was later matched and favorable compared to NBS (p = 0.048). PRO concerning hernia recurrence suggest around 10% at two years of follow-up (p = 0.532)., Conclusion: Use of barbed sutures in VHR is widespread and highly related to MIS. Outcomes from this multicenter database cannot be reported as superior but suggest that barbed sutures do not have a negative impact on outcomes., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2024
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23. Robotic-assisted endoscopic onlay repair (R-ENDOR) for concomitant ventral hernias and diastasis recti: initial results and surgical technique.
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Arias-Espinosa L, Salas-Parra R, Tagerman D, Pereira X, and Malcher F
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- Humans, Female, Middle Aged, Male, Retrospective Studies, Adult, Treatment Outcome, Operative Time, Rectus Abdominis surgery, Hernia, Ventral surgery, Hernia, Ventral complications, Robotic Surgical Procedures methods, Herniorrhaphy methods, Herniorrhaphy instrumentation
- Abstract
Background: The surgical management of midline ventral hernias complicated by concomitant diastasis recti presents a significant clinical challenge. The Endoscopic Onlay Repair (ENDOR) offers a minimally invasive solution, effectively addressing both conditions. This study focuses on describing the adaptation of ENDOR to a robotic platform, termed R-ENDOR, aiming to report initial outcomes along with other established robotic surgical approaches., Methods: This retrospective case series study included consecutive adult patients who underwent R-ENDOR approach from October 2018 to April 2023, performed by a single surgeon. A comprehensive description of the surgical technique is included. Patient demographics, operative, and hernia-specific characteristics, as well as clinical outcomes are described., Results: A total of 15 patients undergoing R-ENDOR for ventral hernia repair with diastasis recti plication were included. The median age was 59 years (IQR 42-63), with 60% (n = 9) female patients. The majority (86%, n = 13) had an ASA score of ≤ 2, and the median BMI was 24 kg/m
2 , with 20% (n = 3) classified as obese. Median hernia size was 2 cm (IQR 2-2.25), with a median diastasis length of 19 cm (IQR 15-21.5) and width of 4 cm (IQR 3-6). The median operative time was 129 min (IQR 113-166). Most repairs (93%, n = 14) were reinforced with mesh, predominantly self-fixating (73.3%, n = 11). Eighty percent of patients (n = 12) were discharged on the same day, with a median follow-up of 153 days (IQR 55-309). Notable complications included clinically significant seromas in 20% of patients (n = 3), long-term hypoesthesia in 40% (n = 6), and readmission in one patient (6.6%) for surgical site infection (SSI) requiring IV antibiotic therapy., Conclusion: Midline ventral hernias associated to diastasis recti can be managed robotically by ENDOR with safe and consistent 90-day outcomes in a carefully selected group of patients., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2024
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24. Comparison of short-term outcomes following robotic ventral hernia repair in patients with obesity: a review of 9742 patients from the Abdominal Core Health Quality Collaborative database.
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Taylor JS, López-Cañizares N, Valor C, Arias-Espinosa L, Phillips S, Pereira X, Damani T, and Malcher F
- Subjects
- Humans, Middle Aged, Female, Aged, Male, Adult, Retrospective Studies, Treatment Outcome, Aged, 80 and over, Body Mass Index, Adolescent, Young Adult, Quality of Life, Databases, Factual, Hernia, Ventral surgery, Robotic Surgical Procedures methods, Herniorrhaphy methods, Herniorrhaphy adverse effects, Obesity complications, Postoperative Complications epidemiology, Postoperative Complications etiology
- Abstract
Despite the paucity of evidence on robotic ventral hernia repair (RVHR) in patients with obesity, the robotic platform is being used more frequently in hernia surgery. The impact of obesity on RVHR outcomes has not been thoroughly studied. Obesity is considered a major risk factor for the development of recurrent ventral hernias and postoperative complications; however, we hypothesize that patients undergoing robotic repairs will have similar complication profiles despite their body mass index (BMI). We performed a retrospective analysis of patients aged 18-90 years who underwent RVHR between 2013 and 2023 using data from the Abdominal Core Health Quality Collaborative registry. Preoperative, intraoperative, and postoperative characteristics were compared in non-obese and obese groups, determined using a univariate and logistic regression analysis to compare short-term outcomes. The registry identified 9742 patients; 3666 were non-obese; 6076 were classified as obese (BMI > 30 kg/m
2 ). There was an increased odds of surgical site occurrence in patients with obesity, mostly seroma formation; however, obesity was not a significant factor for a complication requiring a procedural intervention after RVHR. In contrast, the hernia-specific quality-of-life scores significantly improved following surgery for all patients, with those with obesity having more substantial improvement from baseline. Obesity does increase the risk of certain complications following RVHR in a BMI-dependent fashion; however, the odds of requiring a procedural intervention are not significantly increased by BMI. Patients with obesity have a significant improvement in their quality of life, and RVHR should be carefully considered in this population., (© 2024. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.)- Published
- 2024
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25. Gastric bypass revisional surgery: percentage total body weight loss differences among three different techniques.
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Estrada A, Rodriguez-Quintero JH, Pereira X, Moran-Atkin E, Choi J, and Camacho D
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- Adult, Female, Humans, Male, Middle Aged, Cohort Studies, Retrospective Studies, Gastric Bypass methods, Obesity, Morbid surgery, Reoperation, Weight Loss
- Abstract
Introduction: Suboptimal weight loss or weight regain may occur after Roux-en-Y gastric bypass (RYGB). For this reason, revisional surgery has gained increasing interest. We aimed to compare the percentage of total body weight loss (%TBWL) at one-year follow-up among three different techniques: Jejuno-jejunostomy distalization (JJD), Sleeve resection of the gastrojejunostomy and gastric pouch (SRGJP), and the combination of both (JJD + SRGJP)., Methods: This retrospective cohort study included all patients who underwent revisional surgery after RYGB (2020-2021). The cohort was stratified by the type of revisional technique performed. Postoperative bariatric outcomes and nutritional deficiencies were compared among groups., Results: A total of 78 patients underwent revisional surgery after RYGB: JJD was performed in 8 (10.3%), SRGJP in 34 (43.6%), and JJD + SRGJP in 36 (46.1%) patients. The most common indication for surgery was weight regain, in 72 (92.3%) patients. The median lengths of the BP limbs before and after distalization, were 50 cm (IQR 40-75 cm) and 175 cm (IQR 150-200 cm), respectively. The median length of the new common limb (NCL) and total alimentary limb length (TALL) were 277 cm (IQR 250-313 cm) and 400 cm (IQR 375-475 cm), respectively. Median percentage of total body weight loss (%TBWL) at one year was 15% (IQR 15-19%) for JJD, 20% (IQR 13-26%) for SRGJP, and 21% (IQR 15- 28%) for JJD + SRGJP (p = 0.40)., Conclusions: In this study, the combined procedure (JJD + SRGJP) exhibited higher %TBWL at one year, however no statistically significant difference was identified among the three techniques., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2024
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26. Don't Fear the Bleed: Assessing Postoperative Bleeding Incidence After Instituting a Standardized Prophylactic Heparin Protocol in Bariatric Patients.
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Chin R, Berk R, Tagerman D, Pereira X, Friedmann P, and Camacho D
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- Humans, Retrospective Studies, Female, Male, Middle Aged, Adult, Incidence, Clinical Protocols, Bariatric Surgery adverse effects, Postoperative Hemorrhage epidemiology, Postoperative Hemorrhage prevention & control, Venous Thromboembolism prevention & control, Venous Thromboembolism etiology, Venous Thromboembolism epidemiology, Heparin administration & dosage, Heparin adverse effects, Anticoagulants administration & dosage, Anticoagulants therapeutic use
- Abstract
Background: Bariatric surgery is a frequently performed procedure in the United States, accounting for ∼40,000 procedures annually. Patients undergoing bariatric surgery are at high risk for postoperative thrombosis, with a venous thromboembolism (VTE) rate of up to 6.4%. Despite this risk, there is a lack of guidelines recommending postoperative VTE prophylaxis and it is not routine practice at most hospitals. The postoperative bleeding rate after bariatric surgery is only 1.5%; however, the risk of bleeding may lead to hesitancy for more liberal VTE prophylaxis. Methods: This is a retrospective analysis of bariatric surgeries at a single institution in 2019 and 2021. Data were obtained from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) and electronic medical record review for all patients undergoing sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), or conversion to RYGB. The primary outcomes were composite bleeding events, which included postoperative transfusion, postoperative endoscopy or return to operating room (OR) (for bleeding), intra-abdominal hematoma, gastrointestinal (GI) bleeding, or incisional hematoma. Results: There were a total of 2067 patients in the cohort, with 1043 surgeries in 2019 and 1024 surgeries in 2021. There was no difference between bleeding events after instituting a deep venous thrombosis (DVT) prophylaxis protocol in 2021 (27 versus 28 events, P = .76). There was no difference in individual bleeding events between 2019 and 2021. Additionally, there was no significant difference in the rate of VTE between 2019 and 2021 (2 versus 5 events, P = .28). Conclusions: After instituting a standard protocol of prophylactic heparin postdischarge, we did not find an increased rate of bleeding events in patients undergoing bariatric surgery. Thus, surgeons can consider prescribing postdischarge chemical VTE prophylaxis without concern for bleeding.
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- 2024
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27. Hiatal hernia repair with biosynthetic mesh reinforcement: a qualitative systematic review.
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Lima DL, de Figueiredo SMP, Pereira X, Murillo FR, Sreeramoju P, Malcher F, and Damani T
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- Humans, Surgical Mesh, Herniorrhaphy methods, Recurrence, Treatment Outcome, Retrospective Studies, Hernia, Hiatal surgery, Laparoscopy methods
- Abstract
Introduction: Reinforcement of crural closure with synthetic resorbable mesh has been proposed to decrease recurrence rates after hiatal hernia repair, but continues to be controversial. This systematic review aims to evaluate the safety, efficacy, and intermediate-term results of using biosynthetic mesh to augment the hiatus., Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed throughout this systematic review. The Risk of Bias in Non-Randomized Studies of Interventions and Risk of Bias in Randomized Trials tools were used to perform qualitative assessment of all studies included in this review. Recommendations were then summarized for the following pre-defined key items: protocol, research question, search strategy, study eligibility, data extraction, study design, risk of bias, publication bias, and statistical analysis., Results: The systematic literature search found 520 articles, 101 of which were duplicates and 355 articles were determined to be unrelated to our study and excluded. The full text of the remaining 64 articles was thoroughly assessed. A total of 18 articles (1846 patients) were ultimately included for this review, describing hiatal hernia repair using three different biosynthetic meshes-BIO-A, Phasix ST, and polyglactin mesh. Mean operative time varied from 127 to 223 min. Mean follow up varied from 12 to 54 months. There were no mesh erosions or explants. One mesh-related complication of stenosis requiring reoperation was reported with BIO-A. Studies showed significant improvement in symptom and quality-of-life scores, as well as satisfaction with surgery. Recurrence was reported as radiologic or clinical recurrence. Overall, recurrence rate varied from 0.9 to 25%., Conclusion: The use of biosynthetic mesh is safe and effective for hiatal hernia repair with low complications rates and high symptom resolution. The reported recurrence rates are highly variable due to significant heterogeneity in defining and evaluating recurrences. Further randomized controlled trials with larger samples and long-term follow-up should be performed to better analyze outcomes and recurrence rates., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2023
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28. Outcomes in Minimally Invasive Sleeve Gastrectomy and Implications for Surgical Resident Education.
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Lima DL, Profeta RD, Berk R, Pereira X, Moran-Atkin E, Choi J, and Camacho D
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- Humans, Retrospective Studies, Gastrectomy methods, Postoperative Complications etiology, Treatment Outcome, Internship and Residency, Obesity, Morbid surgery, Bariatric Surgery methods, Laparoscopy methods, Gastric Bypass methods
- Abstract
Introduction: Resident participation in advanced minimally invasive and bariatric surgeries is controversial. The aim of this study is to evaluate the safety of resident participation in robotic and laparoscopic sleeve gastrectomy (SG). Methods: Prospectively maintained institutional Metabolic and Bariatric Surgery Accreditation Quality Improvement Program database was used to identify patients who underwent SG, which was performed at our institution between January, 2018, and December, 2021. Operative notes were reviewed to determine the training level of the assistant. These were then classified into 7 groups: postgraduate years 1-5 residents, bariatric fellow (6), and attending surgeons (7). Each group was stratified and their outcomes, which included duration of surgery, length of stay (LOS), postoperative complications, readmissions, and reoperations, were compared. Results: Out of 2571 cases, the assistants for the procedures were minimally invasive surgery (MIS) fellows ( n = 863, 58.8%), fifth- and fourth-year residents ( n = 228, 15.5%), third- and second-year residents ( n = 164, 11.2%), no assistants ( n = 212, 14.5%), and 134 robotic SG. Mean body mass index was higher in cases wherein the attending surgeon performed by himself (47.1, standard deviation 7.7) when compared with other groups. There were no conversions to open. Mean LOS was 1.3 days, and there was no difference between groups ( P = .242). Postoperative complications were low, with 11 reoperations in 30 days (3.3%) and no difference between groups. There was no mortality in 30 or 90 days. Conclusion: Postoperative outcomes were similar for patients who underwent SG regardless of the assistant's level of training. Including residents in bariatric procedures is safe and does not affect patient safety. Encouraging residents to participate in complex MIS procedures is recommended as part of their training.
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- 2023
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29. Effectiveness of Bariatric Surgery Targeting Opioid Prescriptions (BSTOP) protocol on postoperative pain control.
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Seu R, Pereira X, Goriacko P, Yaghdjian V, Appiah D, Moran-Atkin E, Camacho D, Kim J, and Choi J
- Subjects
- Humans, Analgesics, Opioid therapeutic use, Gabapentin therapeutic use, Prospective Studies, Pain, Postoperative drug therapy, Pain, Postoperative prevention & control, Pain, Postoperative epidemiology, Morphine therapeutic use, Prescriptions, Retrospective Studies, Bariatric Surgery adverse effects, Opioid-Related Disorders etiology
- Abstract
Background: Surgical pain management is a critical component in the success of bariatric procedures. With the opioid epidemic, there have been increased efforts to decrease opioid use. In 2019, the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program developed the BSTOP protocol, a multimodal perioperative pain management regimen to minimize opioid use. The objective of this study is to evaluate the effectiveness of the BSTOP protocol on patients' need for opioid medications during their perioperative care., Methods: This is a single-institution prospective cohort study on patients who underwent bariatric surgery from 10/2019 to 5/2021. Data was collected on morphine equivalent dose of opioids during different stages of inpatient and outpatient care. BSTOP was implemented on 7/2020. Primary outcomes were total inpatient and outpatient opioid use as well as hospital length of hospital stay (LOS). Gabapentin was removed from the protocol between 10/20/2020 and 12/31/2020 due to side effects; it was re-implemented on 1/1/2021 due to observed spikes in opioid use during its absence., Results: 1264 patients who had bariatric surgery between 10/2019 and 5/2021 were included in the study, with 409 patients before (pre-BSTOP) and 855 patients after BSTOP implementation. There was a 36% reduction in total inpatient opiate use and a 57% reduction in total outpatient opiate use. LOS also significantly decreased, from 1.53 to 1.28 days. 179 patients received BSTOP without gabapentin. These patients used more opioids in the post-anesthesia care unit and on the inpatient floors compared to pre-BSTOP and BSTOP with gabapentin patients. With total inpatient and outpatient opioid use, patients on BSTOP without gabapentin used fewer opioids than those pre-BSTOP. However, those on BSTOP without gabapentin used more opioids than those with gabapentin., Conclusion: The BSTOP protocol significantly reduced inpatient and outpatient opioid use as well as LOS. Gabapentin is a crucial component of the BSTOP protocol., (© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2023
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30. Assessing outcomes in laparoscopic vs open surgical management of adhesive small bowel obstruction.
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Chin RL, Lima DL, Pereira X, Romero-Velez G, Friedmann P, Dawodu G, Sterbenz K, Yamada J, Sreeramoju P, Smith V, and Malcher F
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- Humans, Retrospective Studies, Treatment Outcome, Postoperative Complications surgery, Length of Stay, Intestinal Obstruction surgery, Laparoscopy methods
- Abstract
Background: Small bowel obstruction is typically managed nonoperatively; however, refractory small bowel obstructions or closed loop obstructions necessitate operative intervention. Traditionally, laparotomy has long been the standard operative intervention for lysis of adhesions of small bowel obstructions. But as surgeons become more comfortable with minimally invasive techniques, laparoscopy has become a widely accepted intervention for small bowel obstructions. The objective of this study was to compare the outcomes of laparoscopy to open surgery in the operative management of small bowel obstruction., Methods: This is a retrospective analysis of operative small bowel obstruction cases at a single academic medical center from June 2016 to December 2019. Data were obtained from billing data and electronic medical record for patients with primary diagnosis of small bowel obstruction. Postoperative outcomes between the laparoscopic and open intervention groups were compared. The primary outcome was time to return of bowel function. Secondary outcomes included length of stay, 30-day mortality, 30-day readmission, VTE, and reoperation rate., Results: The cohort consisted of a total of 279 patients with 170 (61%) and 109 (39%) patients in the open and laparoscopic groups, respectively. Patients undergoing laparoscopic intervention had overall shorter median return of bowel function (4 vs 6 days, p = 0.001) and median length of stay (8 vs 13 days, p = 0.001). When stratifying for bowel resection, patients in the laparoscopic group had shorter return of bowel function (5.5 vs 7 days, p = 0.06) and shorter overall length of stay (10 vs 16 days, p < 0.002). Patients in the laparoscopic group who did not undergo bowel resection had an overall shorter median return of bowel function (3 vs 5 days, p < 0.0009) and length of stay (7 vs 10 days, p < 0.006). When comparing surgeons who performed greater than 40% cases laparoscopically to those with fewer than 40%, there was no difference in patient characteristics. There was no significant difference in return of bowel function, length of stay, post-operative mortality, or re-admission laparoscopic preferred or open preferred surgeons., Conclusion: Laparoscopic intervention for the operative management of small bowel obstruction may provide superior clinical outcomes, shorter return of bowel function and length of stay compared to open operation, but patient selection for laparoscopic intervention is based on surgeon preference rather than patient characteristics., (© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2023
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31. Can a Fully Articulating Electromechanical Laparoscopic Needle Driver Compare with a Robotic Platform in Transabdominal Preperitoneal Inguinal Hernia Repair?
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Lima DL, Pereira X, and Malcher F
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- Humans, Herniorrhaphy methods, Surgical Mesh, Hernia, Inguinal surgery, Robotic Surgical Procedures methods, Laparoscopy methods
- Abstract
Background: Enhanced laparoscopic instruments are filling the gap between straight-stick laparoscopic equipment and robotic platforms. We sought to evaluate the performance and cost of the HandX™ device during mesh fixation and peritoneal flap closure of transabdominal preperitoneal (TAPP) inguinal hernia repairs. Methods: The video recordings of a consecutive series of TAPP surgeries using the articulated needle driver device were compared with a series of surgeries on the DaVinci robotic platform by a single surgeon. Two critical steps of the procedure were analyzed: mesh fixation and peritoneal closure. A cost analysis between the two platforms was completed. Results: We analyzed 27 cases using the new needle driver and 27 cases using the DaVinci Surgical Robotic system. To evaluate the learning curve (LC) with the HandX device, we created three groups (G1, G2, and G3). The two latter groups were combined and called after LC. Mean fixation time using the DaVinci system was 258.1 seconds (±100.4) compared with 391.5 (±95.9) using the articulating handheld laparoscopic needle driver after LC ( P < .001). The average time for peritoneal closure was 418.6 (±192.1) seconds for DaVinci and 634.5 (±159.5) seconds for HandX ( P < .001). When comparing the after-LC HandX cases and the DaVinci system stratified by side, there was no significant difference in peritoneal closure in the right side (520.1 seconds (84.3) with the HandX versus 444.2 seconds (229.7) using the DaVinci system ( P = .353). When evaluating direct cost of the instruments, HandX cases had a lower cost (310 USD) when compared with the cost of using DaVinci (973 USD). Conclusions: The new smart articulating needle driver may be a cost-effective means of bringing some of the benefits of the robotic platform to laparoscopy.
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- 2022
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32. Decreasing Surgical Site Infection Associated with the Use of Circular Staplers During Roux-En-Y Gastric Bypass.
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Garcia Cabrera AT, Romero-Velez G, Pereira X, Vazzana JT, and Camacho DR
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- Humans, Surgical Wound Infection epidemiology, Surgical Wound Infection prevention & control, Povidone-Iodine, Body Mass Index, Gastric Bypass adverse effects, Abdominal Wall
- Abstract
Background: Laparoscopic Roux-en-Y gastric bypass (LRYGB) has been established as a leading treatment of obesity. Surgical site infections (SSIs) remain the most common complication., Objective: To compare the incidence of SSIs before and after the implementation of our technique., Methods: Our intraoperative technique limits enteric contact with the abdominal wall through a wound protector at the end-to-end anastomosis stapler port site, with enteric retrieval with a specimen bag followed by betadine irrigation. We analyzed our SSIs outcomes before and after implementation of our technique in all RYGB and laparoscopic sleeve-to-bypass conversions at our institution performed by two providers between January 1, 2009 to December 31, 2011 and January 1, 2019 to December 31, 2021. We compared patient age, sex, body mass index, American Society of Anesthesiologists class; and comorbidities including hypertension, diabetes, and hyperlipidemia. The χ
2 , Fischer exact, Wilcoxon Rank Sum tests, and multivariate analysis were performed., Results: Four hundred twenty-nine patients underwent LRYGB and sleeve-to-bypass conversion during the two study periods. Group 1 (162 patients, 37.76%) all underwent RYGB. Group 2 (267 patients, 62.24%) of whom 199 underwent RYGB and 68 underwent a laparoscopic sleeve-to-bypass conversion. The SSI rate was 9.26% in Group 1 and 2.62% in Group 2 (p = 0.002514). Statistical significance was also noted for operating room time (137 min vs 123 min, p = 0.02) and hospital length of stay (2 - 3 interquartile range vs 1 - 2 interquartile range, p = 0.04)., Conclusion: We propose a safe, reproducible technique that significantly reduces SSI rates during LRYGB., (© 2022 by SLS, Society of Laparoscopic & Robotic Surgeons.)- Published
- 2022
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33. Postoperative pneumonia after bariatric surgery during the COVID-19 pandemic: a National Surgical Quality Improvement Program study.
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Grosser R, Romero-Velez G, Pereira X, Moran-Atkin E, Choi J, and Camacho DR
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- Cross-Sectional Studies, Gastrectomy methods, Humans, Pandemics, Postoperative Complications epidemiology, Postoperative Complications etiology, Postoperative Complications surgery, Quality Improvement, Retrospective Studies, Treatment Outcome, Bariatric Surgery methods, COVID-19 epidemiology, Gastric Bypass methods, Laparoscopy methods, Obesity, Morbid complications, Obesity, Morbid epidemiology, Obesity, Morbid surgery, Pneumonia epidemiology, Pneumonia etiology
- Abstract
Background: During the COVID-19 pandemic, surgical centers had to weigh the benefits and risks of conducting bariatric surgery. Obesity increases the risk of developing severe COVID-19 infections, and therefore, bariatric surgery is beneficial. In contrast, surgical patients who test positive for COVID-19 have higher mortality rates., Objective: This study investigates the national prevalence of postoperative pneumonia during the COVID-19 pandemic in the bariatric surgery population., Setting: The American College of Surgeons National Surgical Quality Improvement Project (ACS-NSQIP) database., Methods: This is a cross-sectional study using the ACS-NSQIP database. The population of concern included patients who underwent sleeve gastrectomy and Roux-en-Y gastric bypass procedures. Information was extracted on rate of postoperative pneumonia and other 30-day complications between 2018 and 2020., Results: All baseline characteristics were similar among patients who underwent bariatric surgery between 2018 and 2020. However, there was a 156% increase in postoperative pneumonia in 2020 compared with the previous year. Furthermore, despite the similar postoperative complication rates across the years, there was a statistically significant increase in all-cause mortality in 2020. The multivariate analysis showed that having surgery in 2020 was a statistically significant risk factor for pneumonia development postoperatively., Conclusions: This study showed a statistically significant increase in the prevalence of postoperative pneumonia during the COVID-19 pandemic among bariatric surgery patients. Surgical centers must continuously evaluate the risks associated with healthcare-associated exposure to COVID-19 and weigh the benefits of bariatric surgery., (Copyright © 2022. Published by Elsevier Inc.)
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- 2022
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34. Surgical Outcomes During the First Year of the COVID-19 Pandemic.
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Romero-Velez G, Pereira X, Ramos-Santillan V, and Camacho DR
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- Humans, Pandemics, SARS-CoV-2, Treatment Outcome, COVID-19 epidemiology
- Abstract
Competing Interests: The authors declare no conflicts of interest.
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- 2022
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35. Safety and efficacy of roux-en-y gastric bypass in older aged patients.
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Quintero JHR, Grosser R, Velez GR, Ramos-Santillan VO, Pereira X, Flores FM, Choi J, Moran-Atkin E, Camacho D, and Lima DL
- Subjects
- Aged, Gastrectomy, Humans, Middle Aged, Retrospective Studies, Treatment Outcome, Weight Loss, Bariatric Surgery, Gastric Bypass adverse effects, Laparoscopy adverse effects, Obesity, Morbid surgery
- Abstract
Introduction: laparoscopic Roux-en-Y Gastric Bypass (LRYGB) has been a revolutionary intervention for weight loss with reduction of up to 60-70% of excess body weight. However, these outcomes are not as well validated at the extremes of age, where the safety of the intervention still has some caveats. The aim of this study is to assess the efficacy and safety of primary LRYGB among different age groups., Methods: the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database was queried for patients who underwent primary LRYGB from January 2014 to December 2017 at a single institution. Four groups were created and compared by dividing our sample by age quartiles. The primary outcome was percent excess weight loss (%EWL) at 1 year. Additional operative outcomes and complications were also compared across groups., Results: a total of 1013 patients underwent non-revisional LRYGB during the study period. Mean %EWL at one year was 55%. When compared between quartiles, there was a statistically significant difference in %EWL: 1st 62%, 2nd 57%, 3rd 54% and 4th 47% (p=0.010). The differences in the secondary outcomes between age groups did not demonstrate statistical significance., Conclusions: though patients in the fourth age quartile (range) did not demonstrate a statistically significant increase in adverse outcomes, they did lose less weight compared to other cohorts. The %EWL at one year after RYGB varied by age in our cohort. Goals after bariatric surgery should be individualized as weight loss is less robust with aging.
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- 2022
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36. Risk Factors for Surgical Site Infection in the Undeserved Population After Ventral Hernia Repair: A 3936 Patient Single-Center Study Using National Surgical Quality Improvement Project.
- Author
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Romero-Velez G, Lima DL, Pereira X, Farber BA, Friedmann P, Malcher F, and Sreeramoju P
- Subjects
- Herniorrhaphy adverse effects, Herniorrhaphy methods, Humans, Quality Improvement, Retrospective Studies, Risk Factors, Surgical Wound Infection epidemiology, Surgical Wound Infection etiology, Surgical Wound Infection surgery, United States epidemiology, Hernia, Ventral complications, Incisional Hernia complications, Incisional Hernia epidemiology, Incisional Hernia surgery
- Abstract
Background: Ventral hernia repair (VHR) is one of the most common surgical procedures performed in the United States. Surgical site infections (SSI) carry significant morbidity for the patient and pose a very challenging problem for the surgeon, associated with up to 6.6% of cases. Thus, surgeons should be well versed in the risk factors implicated in SSI after VHR. Given the high burden of diabetes, obesity, and smoking in our patient population, we sought to study the rate of SSI and the risk factors that led to SSI in our population. Study Design: This is a retrospective study using the American College of Surgeons-National Surgical Quality Improvement Project (ACS-NSQIP) database for the years 2014-2019. We identified patients who underwent VHR at a single institution in the Bronx, New York. The rate of SSI was calculated, and then, risk factors for SSI were identified using logistic regression analysis. Results: A total of 3936 patients underwent VHR. Incisional hernias made up 41% of the cohort, and there were 37.4% laparoscopic repairs. During the 30-day follow-up, SSI was identified in 101 patients (2.6%). Factors associated with SSI include emergent surgery (adjusted odds ratio [aOR] = 2.57), body mass index >35 kg/m
2 (aOR = 2.38), insulin-dependent diabetes mellitus (aOR = 2.36), and incisional hernia (aOR = 1.81). In addition, a laparoscopic approach was found to be a protective factor (aOR = 0.43, 95% confidence interval 0.25-0.75). Surprisingly, different from other studies, smoking cigarettes was not associated with SSI in our cohort. Conclusions: The rate of SSI after VHR in our institution is 2.6%, which is within that reported in the literature. Most of the variables associated with SSI are modifiable and are similar to those previously reported. Laparoscopic repairs appear to be protective for its occurrence.- Published
- 2022
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37. Hernia Defect Closure With Barbed Suture: An Assessment of Patient-reported Outcomes in Extraperitoneal Robotic Ventral Hernia Repair.
- Author
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Tagerman D, Pereira X, Lima D, Romero-Velez G, Friedman P, Sreeramoju P, and Malcher F
- Subjects
- Adult, Herniorrhaphy adverse effects, Humans, Pain etiology, Patient Reported Outcome Measures, Quality of Life, Recurrence, Retrospective Studies, Surgical Mesh, Sutures, Hernia, Ventral etiology, Hernia, Ventral surgery, Laparoscopy, Robotic Surgical Procedures
- Abstract
Background: Primary closure of a fascial defect during ventral hernia repair is associated with lower rates of recurrence and better patient satisfaction compared with bridging repairs. Robotic surgery offers enhanced ability to close these defects and this has likely been aided by the use of barbed suture. The goal of this study was to evaluate the perioperative safety and the long-term outcomes for the use of barbed suture for the primary closure of hernia defects during robotic ventral hernia repair (rVHR) with mesh., Methods: This is a retrospective study of adult patients who underwent rVHR with the use of a barbed suture for fascial defect closure from August 2018 to August 2020 in an academic center. All the patients included were queried by phone to complete a quality of life assessment to assess patient-reported outcomes (PROs). Subjective sense of a bulge and pain at the previous hernia site has been shown to correlate with hernia recurrence. These questions were used in conjunction with a Hernia-related Quality of Life Survey (HerQles) score to assess a patient's quality of life., Results: A total of 81 patients with 102 hernias were analyzed. Sixty patients (74%) were successfully reached and completed the PRO form at median postoperative day 356 (range: 43 to 818). Eight patients (13% of patients with PRO data) claimed to have both a bulge and pain at their previous hernia site, concerning for possible recurrence. Median overall HerQLes score was 82 [Interquartile Range (IQR): 54 to 99]. Patients with a single hernia defect, when compared with those with multiple defects, had a lower rate of both a bulge (15% vs. 30%) and symptoms (33% vs. 48%), as well as a higher median HerQLes score (85 vs. 62) at the time of PRO follow-up. Patients with previous hernia repair had a lower median HerQLes score of 65 (IQR: 43 to 90) versus 88 (IQR: 62-100). These patients also had a higher rate of sensing a bulge (29% vs. 18%), whereas a sense of symptoms at the site was less (33% vs. 44%)., Conclusions: Barbed suture for fascial defect closure in rVHR was found to be safe with an acceptable rate of possible recurrence by the use of PRO data. Patients with multiple hernias and previous repairs had a higher likelihood of recurrence and a lower quality of life after rVHR., Competing Interests: F.M. discloses consultancy for Intuitive, BD, Medtronic, Integra, Allergan, DeepBlue, and NanoMesh. The remaining authors declare no conflicts of interest., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2022
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38. Comparison of Outcomes Between Banded and Non-banded Sleeve Gastrectomy: a Systematic Review and Meta-analysis.
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Ponce de Leon-Ballesteros G, Romero-Velez G, Martinez-Portilla RJ, Pereira X, Roy-Garcia I, Fobi MAL, and Herrera MF
- Subjects
- Gastrectomy adverse effects, Gastrectomy methods, Humans, Postoperative Complications etiology, Treatment Outcome, Weight Loss, Bariatric Surgery adverse effects, Bariatric Surgery methods, Gastric Bypass methods, Obesity, Morbid surgery
- Abstract
Background: Sleeve gastrectomy (SG) is the most common bariatric procedure performed worldwide. It accounts for more than 50% of primary bariatric surgeries performed each year. Recent long-term data has shown an alarming trend of weight recidivism. Some authors have proposed the concurrent use of a non-adjustable gastric band to decrease long-term sleeve failure., Objective: To compare the outcomes (weight loss) and safety (rate of complication and presence of upper GI symptoms) between SG and BSG., Methods: A systematic search with no language or time restrictions was performed to identify relevant observational studies and randomized controlled trials (RCT) evaluating people with morbid obesity undergoing SG or SGB for weight loss. An inverse-of-the-variance meta-analysis was performed by random effects model. Heterogeneity was assessed using Cochrane X
2 and I2 analysis., Results: A total of 7 observational studies and 3 RCT were included in the final analysis. There were 911 participants pooled from observational studies and 194 from RCT. BSG showed a significant higher excess of weight loss (% EWL). The difference among groups was clinically relevant after the third year where the weighted mean difference (SMD) was 16.8 (CI 95% 12.45, 21.15, p < 0.0001), while at 5 years, a SMD of 25.59 (16.31, 34.87, p < 0.0001) was noticed. No differences related to overall complications were noticed. Upper GI symptoms were up to three times more frequent in the BSG group (OR 3.26. CI 95% 1.96, 5.42, p < 0.0001)., Conclusions: According to the results, BSG is superior to SG in weight loss at 5 years but is associated with a higher incidence of upper GI symptoms. However, these conclusions are based mainly on data obtained from observational studies. Further RCT are needed to evaluate the effect and safety of BSG., (© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2022
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39. Robotic abdominal wall repair: adoption and early outcomes in a large academic medical center.
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Pereira X, Lima DL, Friedmann P, Romero-Velez G, Mandujano CC, Ramos-Santillan V, Garcia-Cabrera A, and Malcher F
- Subjects
- Academic Medical Centers, Herniorrhaphy adverse effects, Humans, Male, Middle Aged, Postoperative Complications etiology, Retrospective Studies, Surgical Mesh adverse effects, Abdominal Wall surgery, Hernia, Inguinal surgery, Laparoscopy adverse effects, Robotic Surgical Procedures methods
- Abstract
Robotic-assisted abdominal wall repair (RAWR) has seen an exponential adoption over the last 5 years. Skepticism surrounding the safety, efficacy, and cost continues to limit a more widespread adoption of the platform. We describe our initial experience of 312 patients undergoing RAWR at a large academic center. A retrospective review of all patients undergoing any RAWR from July 1, 2016 to March 18, 2020 was completed. Patient specific, operation specific, and 30-day outcomes specific data were collected. Univariate analysis and multivariate logistic regression were used to assess factors associated with 30-day complications. There was a steady adoption of RAWR over the study period. A total of 312 patient were included, 138 (44%) were abdominal wall repairs and 174 (56%) were inguinal repairs. The mean age of the cohort was 54.2 years (SD 16), 69% were males, and the mean BMI was 29 kg/m
2 (SD 4.8). There were two reported intraoperative events and nine operative conversions. 60 patients had at least one complication at 30-days. These include: 52 seromas, 4 hematomas, 2 surgical-site infections, 1 deep venous thrombus, and 1 recurrence at 30-days. BMI, type of hernia, and sex were not associated with complications at 30-days. The use of absorbable mesh, longer hospital stay, operative conversion, previous repair, and expert hernia surgeon were significant predictors of 30-day complications. Age, operative conversion, and previous repair were the only predictors of 30-day complications on multivariate regression. Our initial experience of 312 patients demonstrates the adoption and comparable short-term outcomes for a wide variety of robotic-assisted hernia repairs., (© 2021. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.)- Published
- 2022
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40. VERSATILITY OF POLY-4-HYDROXYBUTYRATE (PHASIX™) MESH IN ABDOMINAL WALL SURGERY.
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Lima DL, Estrada A, Pereira X, Alcabes A, Sreeramoju P, and Malcher F
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Escherichia coli, Humans, Hydroxybutyrates, Middle Aged, Polymers, Recurrence, Retrospective Studies, Surgical Mesh, Treatment Outcome, Young Adult, Abdominal Wall surgery, Hernia, Ventral surgery
- Abstract
Background: Poly-4-hydroxybutyrate (P4HB) is a naturally occurring polymer derived from transgenic E. coli bacteria with the longest degradation rate when compared to other available products. This polymer has been manufactured as a biosynthetic mesh to be used as reinforcement when repairing a variety of abdominal wall defects., Objective: We aim to describe our center initial experience with this mesh and discuss the possible indications that may benefit from the use of P4HB mesh., Methods: This is a descriptive retrospective study of patients who underwent abdominal wall repair with a P4HB mesh from October 2018 to December 2020 in a single, large volume, academic center., Results: A total of 51 patients (mean age 54.4 years, range 12-89) underwent abdominal wall reconstruction with a P4HB mesh between October 2018 and December 2020. The mean BMI was 30.5 (range 17.2-50.6). Twenty-three (45%) patients had a prior hernia repair at the site. We grouped patients into six different indications for the use of P4HB mesh in our cohort: clean-contaminated, contaminated or infected field (57%), patient refusal for permanent meshes (14%), those with high risk for post-operative infection (12%), visceral protection of second mesh (10%), recurrence with related chronic pain from mesh (6%), and children (2%). Median follow-up was 105 days (range 8-648). Two patients had hernia recurrence (4%) and 8 (16%) patients developed seroma., Conclusion: P4HB mesh is a safe and a viable alternative for complex hernias and high-risk patients with a low complication rate in the short-term.
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- 2022
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41. In Response to: Impact of COVID-19 Lockdown on Short-Term Weight Loss in a Single Italian Institution-1-Year Updated Data.
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Grosser R, Pereira X, Romero-Velez G, Rodriguez-Quintero JH, and Camacho DR
- Subjects
- Communicable Disease Control, Humans, SARS-CoV-2, Weight Loss physiology, COVID-19, Gastric Bypass, Obesity, Morbid surgery
- Published
- 2022
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42. Preoperative botulinum A toxin as an adjunct for abdominal wall reconstruction: a single-center early experience at an Academic Center in New York.
- Author
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Mandujano CC, Lima DL, Alcabes A, Friedmann P, Pereira X, and Malcher F
- Subjects
- Abdominal Muscles surgery, Adult, Aged, Aged, 80 and over, Hernia, Ventral surgery, Herniorrhaphy, Humans, Middle Aged, New York, Preoperative Care, Abdominal Wall surgery, Botulinum Toxins, Type A therapeutic use, Neuromuscular Agents therapeutic use
- Abstract
Introduction: the botulinum toxin A (BTA) has been used to achieve a chemical component separation, and it has been used with favorable outcomes for the repair of complex ventral hernia (CVH) with and without loss of domain (LD). The aim of this study is to describe our early experience with the chemical component separation in the United Sates., Methods: a retrospective observational study of all patients who underwent ventral hernia repair for CVH with or without LD between July 2018 and June 2020. Preoperative BTA was injected in all patients via sonographic guidance bilaterally, between the lateral muscles to achieve chemical denervation before the operation. Patient demographics, anatomical location of the hernia, perioperative data and postoperative data are described., Results: 36 patients underwent this technique before their hernia repair between July 2018 to June 2020. Median age was 62 years (range 30-87). Median preoperative defect size was 12cm (range 6-25) and median intraoperative defect size was 13cm (range 5-27). Median preoperative hernia sac volume (HSV) was 1338cc (128-14040), median preoperative abdominal cavity volume (ACV) was 8784cc (5197-18289) and median volume ration (HSV/ACV) was 14%. The median OR time for BTA administration was 45 minutes (range 28-495). Seroma was the most common postoperative complication in 8 of the patients (22%). Median follow up was 43 days (range 0-580)., Conclusion: preoperative chemical component separation with BTA is a safe and effective adjunct to hernia repair in CVH repairs where a challenging midline fascial approximation is anticipated.
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- 2022
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43. Is Minimally Invasive Repair the New Gold Standard for Primary Unilateral Inguinal Hernias? Results of an International Survey of Surgeons.
- Author
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Lima RNCL, Lima DL, Romero-Velez G, Pereira X, Shaear M, Bianchi JM, Claus C, Dos Santos DC, and Malcher F
- Subjects
- Herniorrhaphy, Humans, Male, Surgical Mesh, Surveys and Questionnaires, Hernia, Inguinal surgery, Laparoscopy, Surgeons
- Abstract
Background: The Lichtenstein repair has long been heralded as the gold standard for unilateral primary inguinal hernias. However, minimally invasive surgery (MIS) repairs have gained popularity over the past decades given its advantages in recurrent, bilateral, and now even in primary inguinal hernias. We aim to further explore the perception of different techniques among surgeons internationally. Methods: A questionnaire was posted in three closed groups for surgeons and residents on Facebook
® and surgical groups on WhatsApp® . It was also e-mailed to members of the following surgical societies: Mexican Society of Surgery, Brazilian Hernia Society, Asia Pacific Hernia Society, and European Hernia Society. Descriptive and basic comparative statistical analyses were performed. Results: In total, 874 surgeons answered the survey: 759 (86.9%) were male and 418 (47.8%) were from North America, 735 (84.1%) had completed training and 605 (69.2%) considered themselves hernia specialists. If safety profiles of inguinal herniorrhaphy were equal, 533 (61%) would choose MIS. Laparoscopic transabdominal preperitoneal ranked first among preferred techniques if the cost of all techniques was the same. Safety of the procedure followed by experience of the surgeon is the most influential factors. Lastly, hernia specialists were more likely to choose an MIS technique ( P < .0001). Conclusion: When an international sample of 874 attending and trainee surgeons were surveyed about what technique they would prefer to repair their own uncomplicated unilateral inguinal hernia, most chose MIS. Safety of the procedure and the surgeon's experience were the most important factors in choosing a surgical technique.- Published
- 2022
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44. Diagnosis of COVID-19 and the bariatric surgery population: a single center experience.
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Romero-Velez G, Pereira X, Skendelas JP, Costinett S, Grosser R, Creange C, Rodriguez-Quintero JH, Munoz Flores F, Moran-Atkin E, Choi J, Lima DL, and Camacho DR
- Subjects
- Aged, Cross-Sectional Studies, Gastrectomy, Humans, Pandemics, Postoperative Complications epidemiology, Retrospective Studies, SARS-CoV-2, Treatment Outcome, Bariatric Surgery adverse effects, COVID-19, Gastric Bypass, Laparoscopy, Obesity, Morbid complications, Obesity, Morbid surgery
- Abstract
Background: While many cases of the coronavirus disease 2019 (COVID-19) are mild, patients with underlying medical conditions such as hypertension (HTN), diabetes mellitus (DM), older age, and morbid obesity are at higher risk of hospitalization and death. These conditions are characteristic of patients eligible for bariatric surgery, many of whom underwent weight loss procedures in the months prior to cessation of elective surgery in March 2020. The effects of the virus on these high-risk patients who had increased healthcare exposure in the early days of the pandemic are currently unknown., Objectives: To describe the experience of patients who underwent bariatric surgery during the early evolution of the COVID-19 pandemic., Methods: This is a cross-sectional study including patients from a single center who underwent bariatric surgery from January 1st, 2020 to March 18th, 2020. A database was created to analyze patients' demographics, operative variables, and postoperative outcomes. All patients were contacted and a telephone survey was completed to inquire about COVID-19 exposure, symptoms, and testing 30 days before and after surgery., Results: A total of 190 patients underwent bariatric surgery during the study period. Laparoscopic sleeve gastrectomy was the most common procedure (71.6%). One hundred seventy-eight patients (93.7%) completed the telephone survey. Postoperatively, 19 patients (10.7%) reported COVID-19 compatible symptoms, and six patients (3.4%) went on to test positive for COVID-19. There were no COVID-19-related hospital admissions or mortalities in this population., Conclusions: Morbidly obese patients are at high risk of severe disease secondary to COVID-19, and those undergoing bariatric surgery during the evolution of the pandemic reported symptoms at a rate of 10.7% 30 days after the surgery. While none of these patients suffered severe COVID-19 disease, the temporal relationship of their symptomatology and increased exposure to the healthcare system as a result of their surgery suggest an increased risk of disease with elective surgery., (© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.)
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- 2022
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45. The Utility of Hepatobiliary Scintigraphy Scans in the Tokyo Guidelines Era for Acute Cholecystitis.
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Romero-Velez G, Pereira X, Mandujano CC, Parides MK, Muscarella P, Melvin WS, Love C, and McAuliffe JC
- Subjects
- Humans, Male, Radionuclide Imaging, Retrospective Studies, Tokyo, Cholecystitis, Acute diagnostic imaging
- Abstract
Background: Hepatobiliary Scintigraphy (HIDA) aids the diagnosis of acute cholecystitis (AC) but has limitations. We sought to design a model based on the Tokyo Guidelines 2018 (TG18) to predict HIDA results., Methods: A retrospective review of patients who underwent a HIDA scan during the evaluation of AC was performed. Using logistic regression techniques incorporating the TG18 criterion and additional readily available patient characteristics, a prediction model was created to identify patients likely to test negative for acute cholecystitis by HIDA scan., Results: In 235 patients with suspected AC, a HIDA scan was performed. Variables associated with positive HIDA results were male gender (RR 2.0 (CI 1.33-2.99), age (OR 1.02 (CI 1.01-1.04), right upper quadrant tenderness (RR 1.7 (CI 1.1-2.8)), clinical Murphy's sign (RR 2.2 (CI 1.5-3.4)), ultrasound findings suggestive of AC by any of its components (RR 3.2 (CI 1.6-6.5)), gallbladder wall thickening (RR 2.0 (CI 1.3-3.1)), and gallbladder distention (RR 1.9 (CI 1.3-2.9)). These variables allowed for creation of a model to predict HIDA results. The model predicted HIDA results in 36.9% of patients with an area under the curve of 0.81., Conclusions: In the era of TG18, HIDA is probably over utilized. We developed an accurate, simple model based on TG18 that identifies a group of patients for whom a HIDA scan is unnecessary to establish the diagnosis of AC., (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2021
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46. The COVID-19 Pandemic Did Not Affect Target Weight Loss 1 Year Post Bariatric Surgery.
- Author
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Pereira X, Romero-Velez G, Skendelas JP, Rodriguez-Quintero JH, Grosser R, Lima DL, Moran-Atkin E, Choi J, and Camacho D
- Subjects
- Communicable Disease Control, Humans, Pandemics, SARS-CoV-2, Weight Loss, Bariatric Surgery, COVID-19, Obesity, Morbid surgery
- Abstract
Background: Bariatric surgery is one of the most effective treatments for patients with severe and complex obesity. Lifestyle modifications in diet and exercise habits have long been important adjunct to the long-term success after bariatric surgery. The effect of the COVID-19 pandemic on the postoperative bariatric patient is not well understood. We sought to evaluate the impact the COVID-19 pandemic on postoperative weight loss at 1 year in a bariatric cohort., Methods: All patients who underwent bariatric surgery from January 1, 2020, to March 12, 2020, were included. Patients who underwent bariatric surgery during the same period of the two preceding years (2018 and 2019) were included as control groups. Primary end point was %EBMIL at 1 year. A telephone survey was administered to all patients from 2020 to assess for their perception on the effects of the COVID-19 pandemic on weight loss., Results: A total of 596 patients were included: 181 from 2020, 199 from 2019, and 216 from 2018. The response rate was 97% and 53.4% of patients reported that the lockdown affected their ability to lose weight. The %EBMIL at 1 year was 64.1%, 63.7%, and 68.1% for 2020, 2019, and 2018, respectively. There was no difference in weight loss at 1 year (p = 0.77) despite a decrease in exercise activity in those who had surgery just before the pandemic., Conclusion: There was no difference in target weight loss at 1 year in a cohort who underwent bariatric surgery before the pandemic., (© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2021
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47. ROBOTIC TRANS-ABDOMINAL PREPERITONEAL APPROACH (TAPP) APPROACH FOR LATERAL INCISIONAL HERNIAS.
- Author
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Cabrera ATG, Lima DL, Pereira X, Cavazzola LT, and Malcher F
- Subjects
- Herniorrhaphy, Humans, Retrospective Studies, Surgical Mesh, Hernia, Ventral surgery, Incisional Hernia surgery, Laparoscopy
- Abstract
Background: Lateral incisional hernias arise between the linea alba and the posterior paraspinal muscles. Anatomical boundaries contain various topographic variations, such as multiple nearby bony structures and paucity of aponeurotic tissue that make it particularly challenging to repair., Aim: To describe a robotic assisted surgical technique for incisional lumbar hernia repair., Methods: Retrospective data was collected from four patients who underwent robotic-assisted repair of their lumbar hernias after open nephrectomies., Results: Age ranged from 41-53 y. Two patients had right sided flank hernias while the other two on the left. One patient had a recurrent hernia on the left side. The patients were placed in lateral decubitus position contralateral to the hernia defect side. A trans-abdominal preperitoneal approach was used in all cases. Each case was accomplished with two 8 mm robotic ports, a 12 mm periumbilical port, and a 5 mm assistance port that allowed docking on the ipsilateral hernia side. The hernias were identified, a preperitoneal plane was created, and the hernia sac completely dissected allowing for complete visualization of the defect. All defects were primarily closed. Polypropylene or ProGripTM mesh was applied with at least 5 cm overlap and secured using either #0 Vicryl® transfacial sutures, Evicel® or a combination of both. The peritoneal space was closed with running suture and the ports were removed and closed. The average surgical length was 4 hr. The post-operative length of stay ranged from 0-2 days., Conclusion: The robotics platform may provide unique advantages in the repair of lateral incisional hernias and represents a safe, feasible and effective minimally invasive approach for the correction of lateral incisional hernias.
- Published
- 2021
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48. Robotic Inguinal Hernia Repair After Prostatectomy: How to Navigate Safely.
- Author
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Salas-Parra RD, Lima DL, Pereira X, Cavazzola LT, Sreeramoju P, and Malcher F
- Subjects
- Aged, Herniorrhaphy, Humans, Male, Neoplasm Recurrence, Local, Prostatectomy, Retrospective Studies, Surgical Mesh, Hernia, Inguinal surgery, Laparoscopy
- Abstract
Introduction: In recent decades, minimally invasive approaches have found their place in treating a specific subset of patients with inguinal hernias, predominantly those with recurrent or bilateral disease. Classically, prior history of urologic pelvic operations, such as prostatectomy, has been listed as relative contraindication for minimally invasive inguinal hernia repair. As the adoption of the robotics platform continues to grow, we aim to outline a feasible robotic-assisted inguinal hernia repair technique in patients with previous prostatectomies. We report the outcomes of 15 patients who underwent repair at 2 institutions., Methods: This is a retrospective case series of 15 patients who underwent robotic transabdominal preperitoneal approach repair of their inguinal hernias after prostatectomy. Demographics, intraoperative variables, and outcomes of our cases are described., Results: Fifteen patients were included in our cohort. All patients had a history of prostatectomy (7 open, 2 laparoscopic, and 6 robotic) due to prostate cancer. Median age was 70 years old (range: 60 to 89 y), with a median body mass index of 26.3 kg/m2 (range: 20.5 to 37.4 kg/m2). Hernia defects were bilateral in 6 patients and unilateral in the remaining 9 (right; 6, left; 3). The shortest interval between prostatectomy and subsequent hernia repair was 4 months (range: 4 to 216 mo). The median operative time was 139 min (range: 91 to 281 min). All defects were repaired using a polypropylene mesh except in 1 case, where a coated monofilament polyester mesh was used after having a large peritoneal defect to close, preventing future adhesions to the bowel. Mesh sizes used were large (16×11 cm), extra-large (17×12 cm) for anatomic mesh, and 20×15 cm for the monofilament polyester mesh. The mesh was fixed in 14 of 15 cases. Fixation was accomplished with absorbable suture (n=13), barbed suture (n=1), and fibrin sealant (n=1). Peritoneal closure was always performed using a continuous running v-loc suture. There were no documented major intraoperative complications, no 30-day readmission, or recurrences recorded within the follow-up period. Postoperatively, only 2 seromas and 1 hematoma were documented during the follow-up period., Conclusions: Robotic inguinal hernia repairs in patients with previous prostatectomy is safe and feasible in most patients. Larger patient series are needed to confirm these findings., Competing Interests: F.M.: consulting fees from BD, Intuitive & Medtronic, outside the submitted work. L.T.C.: consulting fees from Strattner and Medtronic, outside the submitted work. The remaining authors declare no conflicts of interest., (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2021
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49. Cecal bascule - A rare cause of cecal volvulus after cesarean section.
- Author
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Bakshi C, Pereira X, Massad N, Lima DL, Peskin-Stolze M, and Malcher F
- Abstract
Introduction and Importance: Cecal bascule is a rare form of a cecal volvulus characterized by an anterior and superiorly displaced cecum in turn causing compression of the ascending colon that can result in a large bowel obstruction. We report a case of cecal bascule in a newly postpartum patient, with emphasis on clinical presentation, radiologic findings and treatment., Case Presentation: A 37-year-old female who underwent an uncomplicated c-section and bilateral salpingectomy developed severe abdominal pain, vomiting, and peritonitis 12 h after surgery. A computerized tomography of the abdomen and pelvis revealed a dilated and superiorly displaced cecum. The diagnosis of cecal bascule was confirmed intraoperatively and a right hemicolectomy was performed. The patient recovered appropriately and was discharged on postoperative day six., Discussion: Cecal bascule is the rarest form of cecal volvulus. In the context of obstetrics and gynecology, it has mostly been mentioned perioperatively after cesarean, but was also reported in an antepartum patient. It usually occurs in patients with redundant or mobile cecum, which is a result of incomplete fixation of the cecum to the retroperitoneum during embryogenesis. Other risk factors include recent surgery, previous abdominal surgery, ileus, chronic constipation, and distal colonic obstruction. An association has also been shown with pregnancy or the postpartum abdomen and is hypothesized to be due to mass effect., Conclusion: Cecal bascule is a serious entity requiring a high index of suspicion and warranting greater awareness in the post-natal patient. Clinical diagnosis, prompt imaging, and surgery are important to avoid bowel ischemia and perforation., (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.)
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- 2021
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50. SARS-CoV-2 During Abdominal Operations: Are Surgeons at Risk?
- Author
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Romero-Velez G, Rodriguez Quintero JH, Pereira X, Nussbaum JE, and McAuliffe JC
- Subjects
- Adult, Cross-Sectional Studies, Humans, Peritoneum, Prospective Studies, SARS-CoV-2, COVID-19, Surgeons
- Abstract
Background: The safety of surgery in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients remains unclear. On the basis of data from other viral diseases, it has been assumed that coronavirus disease 2019 (COVID-19) has the potential risk of transmission during surgery. The presence of the virus within the peritoneal fluid and the peritoneal tissues is not known., Materials and Methods: This is a prospective cross-sectional study including adult patients with confirmed COVID-19 who underwent surgery at a single institution. Using specific real-time reverse transcriptase-polymerase chain reaction, the presence of SARS-CoV-2 was determined in abdominal fluid samples., Results: Six patients with COVID-19 underwent abdominal surgery. Five patients were asymptomatic, and 1 had severe disease. SARS-CoV-2 was tested in 20 different samples, all of which resulted negative., Conclusions: SARS-CoV-2 was not found in the peritoneal cavity of 6 patients undergoing abdominal surgery. The risk of transmissibility of COVID-19 during surgery is still unclear., Competing Interests: The author declares no conflicts of interest., (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2021
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- View/download PDF
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