Search

Your search keyword '"Pereira, Ana Maria S."' showing total 98 results
Start Over Author "Pereira, Ana Maria S."
98 results on '"Pereira, Ana Maria S."'

2. Chloroplast genome assembly of Serjania erecta Raldk: comparative analysis reveals gene number variation and selection in protein-coding plastid genes of Sapindaceae

Author

Corvalán, Leonardo C. J., primary, Sobreiro, Mariane B., additional, Carvalho, Larissa R., additional, Dias, Renata O., additional, Braga-Ferreira, Ramilla S., additional, Targueta, Cintia P., additional, Silva-Neto, Carlos M. e, additional, Berton, Bianca W., additional, Pereira, Ana Maria S., additional, Diniz-filho, José A. F., additional, Telles, Mariana P. C., additional, and Nunes, Rhewter, additional

Published
2023
Full Text
View/download PDF

8. Aqueous Pyrostegia venusta (Ker Gawl.) Miers extract attenuates allergen-induced asthma in a mouse model via an antioxidant mechanism

Author

Balestra, Andiamira Cagnoni, primary, Sandy, Camila Mira, additional, Ramalho, Fernando, additional, Júnior, Alceu Afonso Jordão, additional, Contini, Silvia Helena Taleb, additional, Crevelin, Eduardo José, additional, Carmona, Fabio, additional, Pereira, Ana Maria S., additional, and Borges, Marcos C., additional

Published
2020
Full Text
View/download PDF

9. Antibiofilm activity of Croton urucurana compounds against Staphylococcus aureus isolated from mastitis in dairy cattle

Author

Nader, Talita Thomaz [UNESP], Coppede, Juliana S., Taleb-Contini, Silvia Helena, Amaral, Luiz Augusto [UNESP], Pereira, Ana Maria S., Universidade Estadual Paulista (Unesp), and Univ Ribeirao Preto Unaerp

Subjects
isolated, Staphylococcus aureus, cattle, dairy cattle, Euphorbiaceae, bacterioses, mastitis, Antibiofilm, biofilm, Croton urucurana, alpha-Costol
Abstract

Made available in DSpace on 2019-10-04T12:32:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-01. Added 1 bitstream(s) on 2021-07-15T14:34:54Z : No. of bitstreams: 1 S0100-736X2018000901713.pdf: 1192037 bytes, checksum: 50dfebcd32ff1503ec380c6a6d47be76 (MD5) Mastitis in dairy cattle is the disease that impacts dairy production the most; Staphylococcus aureus is the main causative agent of this condition. The genus Staphylococcus has the ability to produce biofilms, an important mechanism of antibiotic resistance. Bearing in mind that plants have therapeutic action, this study investigated the in vitro antibiofilm activity of the plant extract and compounds isolated from the species Croton urucurana, native to the Brazilian Cerrado, against Staphylococcus aureus isolated from the milk of cows with mastitis, as well as the antibiotic gentamycin and vancomicyn. The antibiofilm activity was evaluated by means of violet crystal and the counting of Colony Forming Units. The images were obtained by scanning electron microscopy. The C. urucurana crude extract and fraction displayed better antibiofilm effect than gentamycin; their antibiofilm action was similar to the action of vancomycin. Compared with all the assessed treatments, the isolated compound alpha-Costol was significantly more active it reduced six logarithmic cycles of the bacterial population composing the biofilm. The phytocomplexs and the alpha-Costol substance isolated from Croton urucurana are promising in the fight against one of the main etiological agents of bovine mastitis. Univ Estadual Paulista Julio de Mesquita Filho Un, Dept Med Vet Prevent, Via Acesso Prof Donato Castellane S-N, BR-14884900 Jaboticabal, SP, Brazil Univ Ribeirao Preto Unaerp, Dept Biotecnol Plantas Med, Av Costabile Romano 2201, BR-14096385 Ribeirao Preto, SP, Brazil Univ Estadual Paulista Julio de Mesquita Filho Un, Dept Med Vet Prevent, Via Acesso Prof Donato Castellane S-N, BR-14884900 Jaboticabal, SP, Brazil

Published
2018

10. Aqueous Pyrostegia venusta (Ker Gawl.) Miers extract attenuates allergen-induced asthma in a mouse model via an antioxidant mechanism.

Author

Balestra, Andiamira Cagnoni, Sandy, Camila Mira, Ramalho, Fernando, Júnior, Alceu Afonso Jordão, Contini, Silvia Helena Taleb, Crevelin, Eduardo José, Carmona, Fabio, Pereira, Ana Maria S., and Borges, Marcos C.

Subjects
LABORATORY mice, BRONCHIAL spasm, ASTHMA, ANIMAL disease models, PNEUMONIA
Abstract

Objective:Pyrostegia venusta (Ker-Gawl.) Miers (Bignoniaceae) is a perennial invasive vine, distributed worldwide. In folk medicine, its parts are used for the treatment of inflammatory respiratory diseases. Extracts of P. venusta have antioxidant, antimicrobial, and antinociceptive properties. The aim of this study was to evaluate the effects of two extracts (aqueous and hydroethanolic) of P. venusta in the treatment of asthma in an animal model. Methods: Balb/c mice were sensitized twice with ovalbumin (OVA) intraperitoneally (ip), one week apart, and after one week, challenged with OVA intranasally on four alternate days. Mice were treated ip with 300 mg/kg of aqueous or hydroethanolic extracts for seven consecutive days. Control groups received saline on the same days. Bronchial hyperresponsiveness, production of Th1 and Th2 cytokines, lung and airway inflammation, and antioxidant activity in lung tissue were assessed. Results: Treatment with aqueous extract significantly decreased bronchial hyperresponsiveness, measured by total and tissue resistance and elastance. The administration of hydroethanolic extract did not reduce bronchial hyperresponsiveness. In addition, both extracts significantly reduced total cell and eosinophil counts in bronchoalveolar lavage. Both extracts did not change significantly IL-4, IL-5, IL-9, IL-13, IFN-gamma, and TGF-beta levels. Of note, only the aqueous extract significantly increased the total antioxidant activity and reduced lung inflammation. Conclusion: Aqueous extract of P. venusta reduced bronchial hyperresponsiveness, lung and airway inflammation, probably via an antioxidant mechanism. These results demonstrate that P. venusta may have potential for asthma treatment. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

12. Effect ofCostus spiralis(Jacq.)RoscoeLeaves, Methanolic Extract and Guaijaverin on Blood Glucose and Lipid Levels in a Type II Diabetic Rat Model

Author

Duarte, Regiane C., primary, Taleb-Contini, Silvia H., additional, Pereira, Paulo S., additional, Oliveira, Camila F., additional, Miranda, Carlos Eduardo S., additional, Bertoni, Bianca W., additional, Coppede, Juliana S., additional, Willrich, Guilherme B., additional, Crevelin, Eduardo J., additional, França, Suzelei C., additional, and Pereira, Ana Maria S., additional

Published
2019
Full Text
View/download PDF

14. Genetic structure and chemical diversity in natural populations of Uncaria guianensis (Aubl.) J.F.Gmel. (Rubiaceae)

Author

Honório, Isabela Cristina G., primary, Coppede, Juliana S., additional, Delprete, Piero G., additional, Costa, Frederico Henrique S., additional, Telles, Mariana P. C., additional, Braga, Ramilla S., additional, Diniz-Filho, José Alexandre F., additional, Correa, Valéria S. C., additional, França, Suzelei C., additional, Pereira, Ana Maria S., additional, and Bertoni, Bianca Waleria, additional

Published
2018
Full Text
View/download PDF

17. Precursor-directed Biosynthesis in Tabernaemontana catharinensis as a New Avenue for Alzheimerʼs Disease-modifying Agents.

Author

Musquiari, Bruno, Crevelin, Eduardo J., Bertoni, Bianca W., França, Suzelei de C., Pereira, Ana Maria S., Castello, Ana Carolina Devides, Castillo-Ordoñez, Willian O., Giuliatti, Silvana, and Lopes, Adriana A.

Subjects
ENZYME inhibitors, THERAPEUTIC use of plant extracts, ALKALOIDS, ALZHEIMER'S disease, PRODRUGS, PLANT roots, PLANT extracts, PLANT anatomy, PHENOMENOLOGICAL biology, DESCRIPTIVE statistics, IN vitro studies, MOLECULAR docking
Abstract

Plants produce a high diversity of metabolites that can act as regulators of cholinergic dysfunction. Among plants, the potential of species of the genus Tabernaemontana to treat neurological disorders has been linked to iboga-type alkaloids that are biosynthesized by those species. In this context, precursor-directed biosynthesis approaches were carried out using T. catharinensis plantlets to achieve new-to-nature molecules as promising agents against Alzheimerʼs disease. Aerial parts of T. catharinensis , cultured in vitro, produced 7 unnatural alkaloids (5-fluoro-ibogamine, 5-fluoro-voachalotine, 5-fluoro-12-methoxy-Nb-methyl-voachalotine, 5-fluoro-isovoacangine, 5-fluoro-catharanthine, 5-fluoro-19-(S)-hydroxy-ibogamine, and 5-fluoro-coronaridine), while root extracts showed the presence of the same unnatural iboga-type alkaloids and 2 additional ones: 5-fluoro-voafinine and 5-fluoro-affinisine. Moreover, molecular docking approaches were carried out to evaluate the potential inhibition activity of T. catharinensis ' natural and unnatural alkaloids against AChE and BChE enzymes. Fluorinated iboga alkaloids (5-fluoro-catharanthine, 5-fluoro-voachalotine, 5-fluoro-affinisine, 5-fluoro-isovoacangine, 5-fluoro-corinaridine) were more active than natural ones and controls against AchE, while 5-fluoro-19-(S)-hydroxy-ibogamine, 5-fluoro-catharanthine, 5-fluoro-isovoacangine, and 5-fluoro-corinaridine showed better activity than natural ones and controls against BChE. Our findings showed that precursor-directed biosynthesis strategies generated "new-to-nature" alkaloids that are promising Alzheimerʼs disease drug candidates. Furthermore, the isotopic experiments also allowed us to elucidate the initial steps of the biosynthetic pathway for iboga-type alkaloids, which are derived from the MEP and shikimate pathways. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

24. Oral administration of powdered dried rhizomes of Curcuma longa L. (turmeric, Zingiberaceae) is effective in the treatment of doxorubicin-induced kidney injury in rats.

Author

Russo, Enzo R., Facincani, Inalda, Nakazato, Katia C., Coimbra, Terezila M., Crevelin, Eduardo J., Pereira, Ana Maria S., and Carmona, Fabio

Abstract

Curcumin is a polyphenol present in the rhizomes of the species Curcuma longa L. ("turmeric," Zingiberaceae), which has been used for centuries as an anti-inflammatory. We aimed to evaluate the anti-inflammatory effects of C. longa in renal injury induced by doxorubicin (DOX, 3.5 mg.kg-1 IV). We studied four groups of Wistar rats: two groups with DOX-induced kidney injury, one fed with standard food and another with standard food mixed with C. longa (5 mg.g-1 ). Two other control groups without kidney injury were fed with the same foods. We measured albuminuria, body weight, and food intake every 2 weeks. After 8 weeks, treatment with C. longa did not change albuminuria, but it significantly attenuated the excretion of urinary inflammatory markers monocyte chemoattractant protein-1 (MCP-1) and transforming growth factor-β (TGF-β) and significantly attenuated immunostaining for desmin, vimentin, and ED-1+ cells in renal tissues of rats with DOX-induced kidney injury. In addition, treatment with C. longa resulted in significantly lower glomerular and tubule interstitial injury scores, compared with that in the DOX-STD group. In conclusion, administration of powdered rhizomes of C. longa for 8 weeks to rats with DOX-induced kidney injury did not reduce albuminuria but led to a significant decrease in urinary inflammatory markers MCP-1 and TGF-β and decreased histopathological alterations and immunostaining for desmin, vimentin, and ED-1+ cells kidneys tissues. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

25. Atividade antibiofilme de substâncias de Croton urucurana em Staphylococcus aureus isolado de mastite bovina.

Author

Thomaz Nader, Talita, Coppede, Juliana S., Taleb-Contini, Silvia Helena, Amaral, Luiz Augusto, and Pereira, Ana Maria S.

Abstract

Copyright of Pesquisa Veterinaria Brasileira is the property of Colegio Brasileiro de Patologia Animal - CBPA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
Full Text
View/download PDF

26. Genetic diversity among natural populations of Mandevilla velutina

Author

Bertoni, Bianca Waléria, Souza, Ana Valéria de, Biondo, Ronaldo, França, Suzelei de C, Telles, Mariana PC, and Pereira, Ana Maria S

Subjects
medicinal plant, molecular markers, marcador molecular, extinction risk, planta medicinal, risco de extinção, Mandevilla velutina
Abstract

Mandevilla velutina (Mart. Ex Stadelm) Woodson (Apocynaceae) is an endemic species in the Cerrado (Brazilian Savannah), whose alcoholic extracts and root infusions are extensively used in the popular medicine to treat inflammatory diseases and against snake bites. Currently, this species has been pointed out as crucial in conservation programs. Therefore, studies on its genetic diversity, as well as the development of methodology for in vitro conservation in germplasm banks are imperative to avoid its extinction. The objective of this work was to investigate the intra- and inter-populational genetic variability of M. velutina to enhance the representativeness of germplasm banks. To this aim, we used RAPD molecular markers. The analysis of molecular variance (AMOVA) indicated that the intra-populational (81.25%) was higher than the inter-populational (18.75%) variability, which was confirmed by the Nei's Diversity Index. The PHIst (0.188) and qP (0.1586) values of genetic variation indicated high population structuring. There seems to be no direct correlation between geographic distances and genetic similarity among the three studied populations. A batata-infalível (Mandevilla velutina (Mart. Ex Stadelm) Woodson, Apocynaceae) é uma espécie endêmica do Cerrado, amplamente utilizada na medicina popular na forma de extrato alcoólico ou infusões do sistema subterrâneo. A planta é utilizada no tratamento de processos inflamatórios e em acidentes com serpentes. Atualmente, esta espécie é considerada prioritária em programas de conservação e, por isso, estudos de diversidade genética e métodos de conservação in vitro em bancos de germoplasma são relevantes para evitar sua extinção. O objetivo deste trabalho foi estudar a variabilidade genética em diferentes populações de batata infalível por meio de marcador molecular RAPD visando fornecer subsídios para a conservação da espécie em bancos de germoplasma. A análise molecular de variância (AMOVA) revelou que a variabilidade dentro das populações (81,25%) foi maior que entre populações (18,75%). Esses resultados foram confirmados pelo Índice de diversidade de Nei. As estimativas de variação de PHI ST (0,188) e qP (0,1586) indicaram alta estruturação populacional. Não foi observada uma relação direta entre as distâncias genéticas e geográficas das três populações estudadas.

Published
2010

32. Evaluation of the Hypoglycemic Properties ofAnacardium humileAqueous Extract

Author

Urzêda, Márcio A., primary, Marcussi, Silvana, additional, Silva Pereira, Luciana L., additional, França, Suzelei C., additional, Pereira, Ana Maria S., additional, Pereira, Paulo S., additional, da Silva, Saulo L., additional, Guimarães, César L. S., additional, Calderon, Leonardo A., additional, Stábeli, Rodrigo G., additional, Soares, Andreimar M., additional, and Couto, Lucélio B., additional

Published
2013
Full Text
View/download PDF

45. Biosynthesis of friedelane and quinonemethide triterpenoids is compartmentalized in Maytenus aquifoliumand Salacia campestris

Author

Corsino, Joaquim, de Carvalho, Paulo Roberto F, Kato, Massuo Jorge, Latorre, Leandro Ribeiro, Oliveira, Olga Maria M.F, Araújo, Angela Regina, Bolzani, Vanderlan da S, França, Suzelei C, Pereira, Ana Maria S, and Furlan, Maysa

Abstract

Maytenus aquifolium(Celastraceae) and Salacia campestris(Hippocrateaceae) species accumulate friedelane and quinonemethide triterpenoids in their leaves and root bark, respectively. Enzymatic extracts obtained from leaves displayed cyclase activity with conversion of the substrate oxidosqualene to the triterpenes, 3β-friedelanol and friedelin. In addition, administration of (±)5-3H mevalonolactone in leaves of M. aquifoliumseedlings produced radio labelled friedelin in the leaves, twigs and stems, while the root bark accumulated labelled maytenin and pristimerin. These experiments indicated that the triterpenes once biosynthesized in the leaves are translocated to the root bark and further transformed to the antitumoral quinonemethide triterpenoids.

Published
2000
Full Text
View/download PDF

47. Quantitative determination of maitenin and 22β‐hydroxymaitenin in callus of Maytenus aquifolium(celastraceae) by reverse phase high performance liquid chromatography

Author

Corsino, Joaquim, Alécio, Alberto Camilo, Ribeiro, Maria Lúcia, Furlan, Maysa, Pereira, ­Ana Maria S., Duarte, Ines Batista, and França, Suzelei Castro

Abstract

Explants of Maytenus aquifoliumwere induced to form callus and, subsequently, suspension cultures. The isolation of natural products from callus led to the identification of the cytotoxic triterpene quinonemethides, maitenin (1) and 22β‐hydroxymaitenin (2). A rapid, sensitive and reliable reversed‐phase high‐performance liquid chromatography method was developed using a C18column and isocratic elution for the determination of 1and 2. The elaborated method gave well‐resolved peaks for these compounds with good detection response and linearity in the range of 0.08–72.0 μg. The quantification of 1and 2was performed by an external standard method. © 1998 John Wiley & Sons, Ltd.

Published
1998
Full Text
View/download PDF

49. Chemical Composition and Antifungal Activity of the Essential Oils of Schinus weinmannifoliusCollected in the Spring and Winter

Author

Hernandes, Camila, Taleb-Contini, Silvia H., Bartolomeu, Ana Carolina D., Bertoni, Bianca W., França, Suzelei C., and Pereira, Ana Maria S.

Abstract

Reports on the chemical and pharmacological profile of the essential oil of Schinus weinmannifoliusdo not exist, although other Schinusspecies have been widely investigated for their biological activities. This work aimed to evaluate the chemical composition and antimicrobial activity of the essential oil of S. weinmannifoliuscollected in the spring and winter. The essential oils were extracted by hydrodistillation, analyzed by GC/MS and submitted to microdilution tests, to determine the minimum inhibitory concentration. The oils displayed different chemical composition and antimicrobial action. Bicyclogermacrene and limonene predominated in the oils extracted in the winter and spring, respectively, whereas only the latter oil exhibited antifungal activity.

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results