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218 results on '"Perea, Verónica"'

1. Pregnancy outcomes with the pregestational use of Minimed 780G compared to Minimed 640G: findings from a multicenter cohort study

Author

Perea, Verónica, Quirós, Carmen, Herrera-Arranz, María Teresa, Azriel-Mira, Sharona, Wägner, Ana M., Beato-Vibora, Pilar, Soldevila, Berta, Barquiel, Beatriz, Pardo, Rosa Márquez, Díaz-Soto, Gonzalo, Picón, Maria José, Colomo, Natalia, Amigó, Judit, Climent, Elisenda, Durán-Martínez, María, Corcoy, Rosa, Codina, Mercedes, Cuesta, Martín, Guedes, Begoña Vega, and Vinagre, Irene

Published
2024
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5. Patients who suffer a first atherosclerotic cardiovascular event while taking statins are often far off of lipid targets

Author

Plana, Núria, Andreychuk, Natalia, Ruiz Ortiz, Martín, Herrera, Norberto, José Gómez Doblas, Juan, Rodríguez Capitán, Jorge, Vazquez Garcia, Rafael, Bartolomé, Daniel, Delgado, William, Caldés, Onofre, Gil, Aritz, Perea, Verònica, Sionis, Alessandro, Herráez, Silvia, Jericó, Carles, Pintó, Xavier, María de los Ángeles Rodríguez, Domènech, Mònica, Luis Santos, José, Enriquez, Eduardo, Arribas, Patricio, García Corrales, Carmen, Bravo Amaro, Marisol, González, Inmaculada, Caneiro, Berenice, Gonzalez Juanatey, Carlos, Méndez Eirin, Elizabet, Curcio Ruigómez, Alejandro, María Jiménez, Rosa, Cristobal, Carmen, Armada Romero, Eduardo, Briongos, Sem, Gabriela Vallarino Terán, Varinia, Pascual, Domingo, Marín Ortuño, Francisco, Tello Montoliu, Antonio, Roy, Ignacio, Facila Rubio, Lorenzo, Montagud, Vicente, Bonanat, Clara, Arrarte Esteban, Vicente, Fuertes, Laura, María García, Ana, Cordero, Alberto, Ángel Arnau, Miguel, Domingo Valero, Diana, Masana, Luis, Díaz Moya, Gema, and Pérez de Isla, Leopoldo

Published
2024
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15. Long-term exposure to PM10 above WHO guidelines exacerbates COVID-19 severity and mortality

Author

Marquès, Montse, Correig, Eudald, Ibarretxe, Daiana, Anoro, Eva, Antonio Arroyo, Juan, Jericó, Carlos, Borrallo, Rosa M., Miret, Marcel·la, Näf, Silvia, Pardo, Anna, Perea, Verónica, Pérez-Bernalte, Rosa, Ramírez-Montesinos, Rafael, Royuela, Meritxell, Soler, Cristina, Urquizu-Padilla, Maria, Zamora, Alberto, Pedro-Botet, Juan, Masana, Lluís, and Domingo, José L.

Published
2022
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20. Frailty Detection in Older Adults with Diabetes: A Scoping Review of Assessment Tools and Their Link to Key Clinical Outcomes.

Author

Guevara, Ernesto, Simó-Servat, Andreu, Perea, Verónica, Quirós, Carmen, Puig-Jové, Carlos, Formiga, Francesc, and Barahona, María-José

Subjects
GLYCEMIC control, OLDER people, FRAILTY, INCLUSION (Disability rights), GERIATRIC assessment
Abstract

Objectives: With the increasing prevalence of diabetes and frailty among older adults, there is an urgent need for precision medicine that incorporates comprehensive geriatric assessments, including frailty detection. This scoping review aims to map and synthesize the available evidence on validated tools for detecting pre-frailty and frailty in community-dwelling elderly individuals with diabetes and outpatient diabetes patients. Specifically, it addresses: (1) What validated tools are available for detecting pre-frailty and frailty in this population? (2) How are these tools associated with outcomes such as glycemic control, hypoglycemia, and metabolic phenotypes? (3) What gaps exist in the literature regarding these tools? Methods: The review followed PRISMA-ScR guidelines, conducting a systematic search across PubMed, Cochrane Library, and Web of Science. The inclusion criteria focused on studies involving individuals aged 70 years and older with diabetes, emphasizing tools with predictive capacity for disability and mortality. Results: Eight instruments met the inclusion criteria, including the Frailty Index, Physical Frailty Phenotype, and Clinical Frailty Scale. These tools varied in domains such as physical, psychological, and social aspects of frailty and their association with glycemic control, hypoglycemia, and metabolic phenotypes. The review identified significant gaps in predicting diabetes-related complications and their clinical application. Conclusions: Routine management of older adults with diabetes should incorporate frailty detection, as it is crucial for their overall health. Although widely used, the reviewed tools require refinement to address the unique characteristics of this population. Developing tailored instruments will enhance precision medicine, leading to more effective, individualized interventions for elderly individuals with diabetes. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Impact of Preeclampsia and Parity on Sex-based Discrepancies in Subclinical Carotid Atherosclerosis in Type 1 Diabetes.

Author

Perea, Verónica, Vinagre, Irene, Serés-Noriega, Tonet, Viñals, Clara, Mesa, Alex, Pané, Adriana, Milad, Camila, Esmatjes, Enric, Conget, Ignacio, Giménez, Marga, and Amor, Antonio J

Subjects
CAROTID artery ultrasonography, TYPE 1 diabetes, ATHEROSCLEROTIC plaque, CARDIOVASCULAR diseases, PREECLAMPSIA, CAROTID intima-media thickness
Abstract

Context The excess risk of fatal and nonfatal cardiovascular events is roughly twice as high in women than in men with type 1 diabetes. Objective To evaluate the impact of preeclampsia and parity on sex-based discrepancies in preclinical atherosclerosis and on the diagnostic performance of a cardiovascular risk scale. Design Cross-sectional study. Setting Single tertiary hospital. Patients A total of 728 people with type 1 diabetes (48.5% women) without cardiovascular disease and age ≥40 years, nephropathy, and/or ≥10 years of diabetes duration with another risk factor. Intervention Standardized carotid ultrasonography. Main Outcome Measures Carotid plaque determined by ultrasonography and cardiovascular risk estimated according to the Steno T1 Risk Engine (Steno-Risk). Results Nulliparous women and parous women without previous preeclampsia had a lower risk for carotid plaque than men (adjusted odds ratio:.48, 95% confidence interval [.28-.82]; adjusted odds ratio:.51 [.33-.79], respectively), without differences in the preeclampsia group. The prevalence of carotid plaque increased as the estimated cardiovascular risk increased in all subgroups except for preeclampsia group. The area under the curve of the Steno-Risk for identifying ≥2 carotid plaques was lower in the preeclampsia group (men:.7886; nulliparous women:.9026; women without preeclampsia:.8230; preeclampsia group:.7841; P between groups =.042). Neither the addition of parity nor preeclampsia in the Steno-Risk led to a statistically significant increase in the area under the curve. Conclusion The risk for carotid plaque in women compared with men decreased as exposure to obstetric factors diminished. However, the addition of these factors did not improve the prediction of the Steno-Risk. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Severe hypoglycemia and hypoglycemia awareness are associated with preclinical atherosclerosis in patients with type 1 diabetes without an estimated high cardiovascular risk

Author

Mesa, Alex, primary, Giménez, Marga, additional, Perea, Verónica, additional, Serés‐Noriega, Tonet, additional, Boswell, Laura, additional, Blanco, Jesús, additional, Milad, Camila, additional, Pané, Adriana, additional, Esmatjes, Enric, additional, Vinagre, Irene, additional, Conget, Ignacio, additional, Viñals, Clara, additional, and Amor, Antonio J., additional

Published
2024
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23. Real-world evidence of off-label use of commercially automated insulin delivery systems compared to multiple daily insulin injections in pregnancies complicated by type 1 diabetes

Author

Quirós, Carmen, primary, Herrera, Maria Teresa, additional, Amigó, Judit, additional, Wagner, Ana, additional, Beato-Vibora, Pilar I, additional, Azriel, Sharona, additional, Climent, Elisenda, additional, Soldevila, Berta, additional, Barquiel, Beatriz, additional, Colomo, Natalia, additional, Durán-Martínez, María, additional, Corcoy, Rosa, additional, Codina, Mercedes, additional, Díaz-Soto, Gonzalo, additional, Márquez-Pardo, Rosa, additional, Martínez-Brocca, María Asunción, additional, Rebollo Román, Ángel, additional, López Gallardo, Gema, additional, Cuesta, Martín, additional, García Fernández, Javier, additional, Goya, María Mar, additional, Vega Guedes, Begoña, additional, Mendoza-Mathison, Lillian C, additional, and Perea, Verónica, additional

Published
2024
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27. Adherence to an energy‐restricted Mediterranean diet is associated with the presence and burden of carotid atherosclerosis in people with type 1 diabetes.

Author

Serés‐Noriega, Tonet, Viñals, Clara, Perea, Verónica, Mesa, Alex, Boswell, Laura, Mariaca, Karla, Blanco, Jesús, Vinagre, Irene, Pané, Adriana, Milad, Camila, Solà, Clara, Esmatjes, Enric, Conget, Ignacio, Giménez, Marga, and Amor, Antonio J.

Subjects
TYPE 1 diabetes, MEDITERRANEAN diet, CAROTID intima-media thickness, DIETARY patterns, DIABETIC nephropathies, ORAL hygiene products
Abstract

Aims: People with type 1 diabetes (T1D) have an increased risk of cardiovascular disease (CVD). The Mediterranean diet is associated with reduced CVD; however, the evidence in T1D is scarce. We aimed to analyse the relationships between adherence to the energy‐restricted Mediterranean diet (erMEDd) and carotid atherosclerosis. Materials and Methods: We included subjects with T1D without CVD, with ≥1 of the following: age ≥40 years, diabetic kidney disease, or ≥10 years of disease duration with another risk factor. Plaque presence (intima‐media thickness ≥1.5 mm) was determined by ultrasonography. The PREDIMED‐Plus 17‐item questionnaire (PP‐17) was used to assess adherence to the erMEDd. Results: Four hundred one individuals were included (48% males, age 48.3 ± 11 years, diabetes duration 26.8 ± 11.4 years). Those harbouring plaques (42%) showed lower adherence to the erMEDd (PP‐17: 8.9 ± 2.3 of a maximum of 17 vs. 9.8 ± 2.5, p < 0.001). Greater adherence to the erMEDd was correlated with an overall better metabolic profile. After adjusting for multiple confounders, adherence to the erMEDd was independently associated with carotid atherosclerosis (OR 0.86 [0.77–0.95] for plaque presence and OR 0.85 [0.75–0.97] for ≥2 plaques). The consumption of fruit and nuts and preference of white over red meat was higher in individuals without atherosclerosis (p < 0.05). Fruit and nut consumption was associated with lower plaque prevalence in the fully adjusted models (OR 0.38 [0.19–0.73] and 0.51 [0.29–0.93]). Conclusions: Greater adherence to the erMEDd is associated with less carotid atherosclerosis in subjects with T1D at high risk of CVD. Strategies to improve and implement healthy dietary patterns in this population should be encouraged. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Impact of conducting a genetic study on the management of familial hypercholesterolemia

Author

Instituto Aragonés de Ciencias de la Salud, Red Nacional de Biobancos (España), Ministerio de Universidades (España), Universidad de Sevilla, Marco-Benedí, Victoria, Cenarro, Ana, Vila, Àlex, Real, José T., Tamarit, Juan J., Álvarez-Sala Walther, Luis A., Diaz-Diaz, Jose Luis, Perea, Verónica, Civeira, Fernando, Vallejo-Vaz, Antonio J., Instituto Aragonés de Ciencias de la Salud, Red Nacional de Biobancos (España), Ministerio de Universidades (España), Universidad de Sevilla, Marco-Benedí, Victoria, Cenarro, Ana, Vila, Àlex, Real, José T., Tamarit, Juan J., Álvarez-Sala Walther, Luis A., Diaz-Diaz, Jose Luis, Perea, Verónica, Civeira, Fernando, and Vallejo-Vaz, Antonio J.

Abstract

[Background] Clinically diagnosed familial hypercholesterolemia (FH) may require a genetic test (GT) to confirm diagnosis. GT availability/accessibility is resource-dependent and usually restricted to specialized clinics. While GT has a diagnostic value, it has not yet defined its impact on long-term management and prognosis of FH., [Objective] The aim was to identify the clinical characteristics associated with the request for a GT in suspected heterozygous FH., [Methods] Retrospective study including adult patients with clinically suspected to be FH. Positive GT (GT+) was defined as having a pathogenic/likely pathogenic variant. Patients were stratified based on whether they had a genetic study conducted, and among those with a genetic study, according to those who did or did not have a GT+., [Results] From 4854 patients included, 3090 were performed a GT (GT+: 2113). Median follow-up: 6.2 years. A younger age, FH-related physical signs, premature coronary disease, higher low-density lipoprotein cholesterol (LDLc) and lower body mass index and triglycerides, associated higher odds of being conducted a genetic study. These patients had higher baseline LDLc (252 mg/dL vs. 211 mg/dL among clinically diagnosed patients) and experienced larger reductions over the follow-up (157.7 mg/dL vs. 113.5 mg/dL, respectively). A similar pattern was observed among patients with GT+ (vs. negative GT). LDLc target attainment was low but increased to 66–95% when a triple combination with statin/ezetimibe/proprotein convertase subtilisin kexin type 9-inhibitor was used. Cardiovascular events occurred in 3.2% and 3.1% of patients who conducted/not conducted a genetic study. Patients conducted a genetic analysis and those with GT+ tended to present the events earlier., [Conclusions] Genetic study, vs. having a clinical-only diagnosis, impacts the management of FH. Cardiovascular prognosis was similar in both groups, perhaps as a result of the more intensive management of patients with a genetic study.

Published
2023

36. Asistencia a la gestante con diabetes. Guía de práctica clínica actualizada en 2014

Author

Acosta, Domingo, Balsells, Montserrat, Ballesteros, Mónica, Bandres, Maria Orosia, Bartha, Jose Luis, Bellart, Jordi, Chico, Ana Isabel, Codina, Mercedes, Corcoy, Rosa, Cortázar, Alicia, Donnay, Sergio, González, Nieves Luisa, Goya, Maria del Mar, Herranz, Lucrecia, López, José, Megía, Ana, Moreno, Eduardo, Mozas, Juan, Ontañón, Marta, Perea, Verónica, Ramirez, Octavio, Rossell, M<ce:sup loc='post">a</ce:sup> Rosa, Rubio, José Antonio, Sancho, M<ce:sup loc='post">a</ce:sup> Antonia, Soldevila, Berta, and Vinagre, Irene

Published
2015
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37. Influence of Maternal Diabetes on the Risk of Neurodevelopmental Disorders in Offspring in the Prenatal and Postnatal Periods

Author

Perea, Verónica, primary, Urquizu, Xavier, additional, Valverde, Maite, additional, Macias, Marina, additional, Carmona, Anna, additional, Esteve, Esther, additional, Escribano, Gemma, additional, Pons, Nuria, additional, Giménez, Oriol, additional, Gironés, Teresa, additional, Simó-Servat, Andreu, additional, Domenech, Andrea, additional, Alonso-Carril, Núria, additional, Quirós, Carme, additional, Amor, Antonio J., additional, López, Eva, additional, and Barahona, Maria José, additional

Published
2022
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40. The Steno Type 1 Risk Engine identifies preclinical atherosclerosis better than the ESC/EASD-2019 Guidelines in adult subjects with type 1 diabetes at high-risk

Author

Serés-Noriega, Tonet, primary, Giménez, Marga, primary, Perea, Verónica, primary, Boswell, Laura, primary, Viñals, Clara, primary, Blanco, Jesús, primary, Vinagre, Irene, primary, Pané, Adriana, primary, Esmatjes, Enric, primary, Conget, Ignacio, primary, and Amor, Antonio J., primary

Published
2022
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42. Use of the Steno T1 Risk Engine Identifies Preclinical Atherosclerosis Better Than Use of ESC/EASD-2019 in Adult Subjects With Type 1 Diabetes at High Risk

Author

Serés-Noriega, Tonet, primary, Giménez, Marga, additional, Perea, Verónica, additional, Boswell, Laura, additional, Viñals, Clara, additional, Blanco, Jesús, additional, Vinagre, Irene, additional, Pané, Adriana, additional, Esmatjes, Enric, additional, Conget, Ignacio, additional, and Amor, Antonio J., additional

Published
2022
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47. Erratum to ‘Novel glycoproteins identify preclinical atherosclerosis among women with previous preeclampsia regardless of type 1 diabetes status’ [Nutrition, Metabolism & Cardiovascular Diseases 31 (2021) 3407–3414]

Author

Amor, Antonio J., primary, Vinagre, Irene, additional, Valverde, Maite, additional, Alonso-Carril, Núria, additional, Urquizu, Xavier, additional, Meler, Eva, additional, López, Eva, additional, Giménez, Marga, additional, Codina, Laura, additional, Conget, Ignacio, additional, Barahona, Maria J., additional, and Perea, Verónica, additional

Published
2022
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48. Effect of statin therapy on SARS-CoV-2 infection-related

Author

Masana, Luís, Correig, Eudald, Rodríguez-Borjabad, Cèlia, Anoro, Eva, Arroyo-Díaz, Juan Antonio, Jericó, Carlos, Pedragosa, Angels, Miret, Marcel·la, Näf, Silvia, Pardo, Anna, Perea, Verónica, Pérez-Bernalte, Rosa, Plana, Nuria, Ramírez-Montesinos, Rafael, Royuela, Meritxell, Soler, Cristina, Urquizu-Padilla, Maria, Pedro-Botet, Juan Carlos, and The Stacov-Xula Research Group

Subjects
SARS-CoV-2, Statins, COVID-19, Mortality, Cardiovascular risk
Abstract

Aim: Assessing the effect of statin therapy at hospital admission for COVID-19 on in-hospital mortality. Methods and results: Retrospective observational study. Patients taking statins were 11 years older and had significantly more comorbidities than patients who were not taking statins. A genetic matching (GM) procedure was performed prior to analysis of the mortality risk. A Cox proportional hazards model was used for the cause-specific hazard (CSH) function, and a competing-risks Fine and Gray (FG) model was also used to study the direct effects of statins on risk.Data from reverse transcription-polymerase chain reaction-confirmed 2157 SARS-CoV-2-infected patients (1234 men, 923 women; age: 67 y/o (IQR 54-78)) admitted to the hospital were retrieved from the clinical records in anonymized manner. 353 deaths occurred. 581 patients were taking statins. Univariate test after GM showed a significantly lower mortality rate in patients on statin therapy than the matched non-statin group (19.8% vs. 25.4%, χ2 with Yates continuity correction: p = 0.027). The mortality rate was even lower in patients (n = 336) who maintained their statin treatments during hospitalization compared to the GM non-statin group (17.4%; p = 0.045). The Cox model applied to the CSH function (HR = 0.58(CI: 0.39-0.89); p = 0.01) and the competing risks FG model (HR = 0.60(CI: 0.39-0.92); p = 0.02) suggest that statins are associated with reduced COVID-19-related mortality. Conclusions: A lower SARS-CoV-2 infection-related mortality was observed in patients treated with statin therapy prior to hospitalization. Statin therapy should not be discontinued due to the global concern of the pandemic or in patients hospitalized for COVID-19.

Published
2022

49. Carotid Ultrasonography as a Strategy to Optimize the Management of Cardiovascular Risk in Patients with Type 1 Diabetes: A Cohort Study

Author

Boswell, Laura, primary, Serés-Noriega, Tonet, additional, Mesa, Alex, additional, Perea, Verónica, additional, Pané, Adriana, additional, Viñals, Clara, additional, Blanco, Jesús, additional, Giménez, Marga, additional, Vinagre, Irene, additional, Esmatjes, Enric, additional, Conget, Ignacio, additional, and Amor, Antonio J., additional

Published
2021
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