1. Vagiallene, a Rearranged C15 Acetogenin from Laurencia obtusa
- Author
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Vassilios Roussis, Efstathia Ioannou, Laura Grauso, Panagiota Papazafiri, Alfonso Mangoni, Stamatios Perdikaris, Perdikaris, Stamatio, Mangoni, Alfonso, Grauso, Laura, Papazafiri, Panagiota, Roussis, Vassilio, and Ioannou, Efstathia
- Subjects
010405 organic chemistry ,Stereochemistry ,Organic Chemistry ,Absolute configuration ,Carbon skeleton ,Laurencia obtusa ,010402 general chemistry ,Circular dichroism spectra ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,chemistry.chemical_compound ,chemistry ,Acetogenin ,Physical and Theoretical Chemistry - Abstract
Vagiallene (1), a rearranged C15 acetogenin with a molecular formula and a carbon skeleton unprecedented in natural products, was isolated as a trace constituent from the organic extract of the red alga Laurencia obtusa from Lefkada island. The planar structure and the relative configuration of 1 were established on the basis of extensive analysis of its spectroscopic data, while its absolute configuration was determined by comparison of its experimental and quantum-mechanically predicted electronic circular dichroism spectra.
- Published
- 2019