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Background Gestational diabetes mellitus (GDM) is a common complication of pregnancy, and previous studies have shown that pregnant women with GDM have a higher risk of developing infectious diseases of the reproductive tract than healthy pregnant women, but relevant cohort studies are rare. Objective To investigate the variation characteristics of vaginal microbiota in pregnant women with GDM at different gestational weeks, to compare the differences of vaginal microbiota between GDM and non-GDM women, and to observe the effects of vaginal microbiota changes on pregnancy outcomes. Methods In this study, we used a consecutive sampling method to recruit pregnant women who established their records and regulated health care at Daxing Teaching Hospital of Capital Medical University from March 2022 to March 2023. They underwent 75 g oral glucose tolerance test (OGTT) at 24-28 weeks of gestation to diagnose GDM. The GDM group was matched 1∶1 with the non-GDM group using propensity score matching method (PSM). Sample of vaginal secretions were collected at 24-28 weeks (stage A), 32-35 weeks (stage B) and 37-40 weeks (stage C) for three vaginal microecological examination, respectively. Based on the results, participants were further divided into the GDM normal vaginal flora subgroup, GDM abnormal vaginal flora subgroup, non-GDM normal vaginal flora subgroup and non-GDM abnormal vaginal flora subgroup, and were followed up until 7 d after delivery to assess pregnancy outcome. Results A total of 426 participants were initially enrolled in this study, and GDM occurred in 141 cases. After PSM mathing, the GDM and non-GDM groups were successfully matched in 122 pairs. In this study, because 9 women with GDM and 5 women without GDM had preterm birth (

We report the case of a 53-year-old man who was diagnosed with Holmes tremor and underwent deep brain stimulation of the ventro-intermediate thalamic nucleus and posterior subthalamic area. We assessed the patients' tremor with the Fahn-Tolosa-Marin Tremor Rating Scale at 1, 3, 6, 12 and 24 months after deep brain stimulation. Deep brain stimulation relieved the patient's tremor during the 24-month follow-up period. [ABSTRACT FROM AUTHOR]

With the rapid development of high-power appliances, the demand for higher power density lithium-ion batteries has soared. Benefitting from its large theoretical capacity and high working voltage, vanadium oxide is considered to be a promising candidate for the next generation of cathode materials for lithium-ion batteries. Among them, orthorhombic V2O5, with characteristics of easy synthesis and high safety, is prominent and gaining much attention. However, the cycling performance of V2O5, affected by low electrical conductivity and easy solubility in the electrolyte, is not satisfactory and this has become a stumbling block on the way to its development. This work reports the V4+ doped V2O5 nanoplate material prepared by the hydrothermal method that has excellent electrochemical properties giving the credit to the increased conductivity and expanded interlayer spacing caused by V4+. After doping with V4+, the specific capacity of the V-V2O5 electrode is as high as 301.1 mAh g−1 at a current density of 100 mA g−1, and even more surprisingly, the capacity of the V-V2O5 electrode is still as high as 158.9 mAh g−1 at an ultra-high current density of 4 A g−1, showing excellent rate performance. This study provides sufficient theoretical support and reference for further exploration of self-doped materials in lithium-ion battery field. [ABSTRACT FROM AUTHOR]