166 results on '"Penco, Sergio"'
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2. 7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors
3. Isoxazolo(aza)naphthoquinones: A new class of cytotoxic Hsp90 inhibitors
4. Novel tumor-targeted RGD peptide–camptothecin conjugates: Synthesis and biological evaluation
5. Palladium Catalyzed Reduction of Aryl Sulfonates. Selectivity Control and Application to Anthracycline Chemistry
6. Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors
7. Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968
8. Synthesis and structure–activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids
9. Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series
10. Short heparin sequences spaced by glycol-split uronate residues are antagonists of fibroblast growth factor 2 and angiogenesis inhibitors
11. Modulation of the Heparanase-inhibiting Activity of Heparin through Selective Desulfation, Graded N-Acetylation, and Glycol Splitting
12. Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin
13. alpha-Regioselectivity in palladium-catalyzed arylation of acyclic enol ethers
14. Abstract 3096: Host antitumor immune response activated by Dual POLA1-HDAC11 inhibitors endowed with a large spectrum of antitumor activity
15. Bis-indols: a novel class of molecules enhancing the cytodifferentiating properties of retinoids in myeloid leukemia cells
16. Abstract 4848: Preclinical antitumor activity of novelDNA polymerase 1 (POLA1)inhibitors
17. Abstract 4195: MIR002: a new POLA1 inhibitor endowed with a large spectrum of antitumor activity
18. A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase
19. Synthesis and cytotoxic activity of new 9-substituted camptothecins
20. SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis
21. Corrigendum to “Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors” [Bioorg. Med. Chem. 18 (2010) 6031–6043]
22. Conjugates of a Novel 7-Substituted Camptothecin with RGD-Peptides as αvβ3 Integrin Ligands: An Approach to Tumor-Targeted Therapy
23. Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors
24. Enol Carbamates as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) Endowed with High Selectivity for FAAH over the Other Targets of the Endocannabinoid System
25. Azetidinones as Zinc-Binding Groups to Design Selective HDAC8 Inhibitors
26. Synthesis, Modeling, and RET Protein Kinase Inhibitory Activity of 3- and 4-Substituted β-Carbolin-1-ones
27. Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968
28. Synthesis and Cytotoxic Activity of Polyamine Analogues of Camptothecin
29. Incorporation of the Unusual Cα-Fluoroalkylamino Acids into Cyclopeptides: Synthesis of Arginine−Glycine−Aspartate (RGD) Analogues and Study of Their Conformational and Biological Behavior
30. Synthesis and Structure−Activity Relationships of a New Series of Retinoid-Related Biphenyl-4-ylacrylic Acids Endowed with Antiproliferative and Proapoptotic Activity
31. Synthesis and Cytotoxic Activity of Substituted 7‐Aryliminomethyl Derivatives of Camptothecin.
32. Synthesis of Cycloalkanoindoles by an Unusual DAST-Triggered Rearrangement Reaction.
33. Undersulfated and Glycol-Split Heparins Endowed with Antiangiogenic Activity
34. A Novel Atypical Retinoid Endowed with Proapoptotic and Antitumor Activity
35. Perspectives in camptothecin development
36. Novel 7-Oxyiminomethyl Derivatives of Camptothecin with Potent in Vitro and in Vivo Antitumor Activity
37. ChemInform Abstract: Novel Cytotoxic 7-Iminomethyl and 7-Aminomethyl Derivatives of Camptothecin.
38. Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin
39. Novel 7-Substituted Camptothecins with Potent Antitumor Activity
40. Synthesis and antitumor activity of a new class of water soluble camptothecin derivatives
41. A new high yield semisynthetic approach to (20s)-9-NH2-camptothecin based on a sequence of palladium-catalysed reductions
42. The Ligand Effect in Copper(I)-Catalyzed Chemoselective Amide Carbamoylation in Cabergoline Synthesis
43. Binding modes of the distamycin analogue FCE-24517 to d(CGTATACG)2.1H and13C sequence-specific assignments
44. Tertiary structure of endothelin-1 in water by 1H NMR and molecular dynamics studies
45. A Facile One-Pot Synthesis of Polyfunctionalized 2-Unsubstituted Benzo[b]furans
46. Synthesis of 5-Alkyl Substituted Uracil Derivatives from Barbituric Acid
47. Conjugates of a Novel 7-Substituted Camptothecin with RGD-Peptides as αvβ3Integrin Ligands: An Approach to Tumor-Targeted Therapy.
48. Heck reaction on anthraquinone derivatives: ligand, solvent and salt effects
49. Palladium-catalyzed reduction of aryl sulfonates. Reduction versus hydrolysis selectivity control
50. A novel synthesis of (+)-4-demethoxydaunomycinone
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