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Erythropoiesis is a multistep process of erythroid cell production that is controlled by multiple regulatory factors. Ribosome rescue factor PELO plays a crucial role in cell meiotic division and mice embryonic development. However, the function of PELO in erythroid differentiation remains unclear. Here, we showed that knockdown of PELO increased hemin‐induced erythroid differentiation of K562 and HEL cells, exhibiting a higher number of benzidine‐positive cells and increased mRNA levels of erythroid genes. PELO knockdown inhibited the proliferation and cell cycle progression and promoted apoptosis of K562 cells. Mechanistically, PELO could regulate the expression of KLF10 through interaction with MYC. Moreover, KLF10 knockdown also enhanced erythroid differentiation of K562 and HEL cells induced by hemin. Collectively, our results demonstrated that PELO regulates erythroid differentiation and increases KLF10 expression levels by interacting with MYC. [ABSTRACT FROM AUTHOR]

Abstract Many devastating plant viruses are transmitted by insect vectors among plant hosts in a persistent-propagative manner. Pelota (Pelo) is an evolutionarily conserved protein involved in the mRNA surveillance system. In this study, it was found that the accumulation of Pelo proteins are slightly decreased during the propagation of the fijivirus southern rice black-streaked dwarf virus (SRBSDV) in rice and transmission vector planthopper (Sogatella furcifera). The tubular protein P7-1 encoded by SRBSDV interacted with Pelo of rice or planthopper vector. Overexpression or knockdown of Pelo expression inhibits the formation of P7-1 tubules in insect cells, further exerting antiviral activity. Furthermore, overexpression or knockout of Pelo expression in transgenic rice plants also inhibits the effective propagation of SRBSDV as well as two other rice viruses of different families. The slight reduction of Pelo accumulation during SRBSDV propagation in rice and insect vectors would avoid Pelo-mediated excessive inhibition of P7-1 tubule formation, ensuring effective virus propagation. Our findings provide insights into how the up- or down-regulated expression of Pelo in rice hosts and insect vectors elevate their resistance to rice viruses.

Many devastating plant viruses are transmitted by insect vectors among plant hosts in a persistent-propagative manner. Pelota (Pelo) is an evolutionarily conserved protein involved in the mRNA surveillance system. In this study, it was found that the accumulation of Pelo proteins are slightly decreased during the propagation of the fijivirus southern rice black-streaked dwarf virus (SRBSDV) in rice and transmission vector planthopper (Sogatella furcifera). The tubular protein P7-1 encoded by SRBSDV interacted with Pelo of rice or planthopper vector. Overexpression or knockdown of Pelo expression inhibits the formation of P7-1 tubules in insect cells, further exerting antiviral activity. Furthermore, overexpression or knockout of Pelo expression in transgenic rice plants also inhibits the effective propagation of SRBSDV as well as two other rice viruses of different families. The slight reduction of Pelo accumulation during SRBSDV propagation in rice and insect vectors would avoid Pelo-mediated excessive inhibition of P7-1 tubule formation, ensuring effective virus propagation. Our findings provide insights into how the up- or down-regulated expression of Pelo in rice hosts and insect vectors elevate their resistance to rice viruses. [ABSTRACT FROM AUTHOR]

La internacionalización es uno de los objetivos de la Educación Superior, aspecto abordado en relación a la iniciativa “El pelo/cabello es epistemología”, actividad de participación binacional, con el (re)conocimiento de temas de estudio tan relevantes como poder, pelo/cabello, feminismo y (anti)racismo. Realizamos la sistematización de un intercambio de experiencias entre la Universidad Técnica “Luis Vargas Torres” de Esmeraldas (Ecuador) y la Universidad de Jaén (España), a través de un proceso iniciado “desde abajo” y que ha propuesto otra forma de cooperar. La metodología ha rodeado el artivismo desde una decidida posición (anti)racista y feminista. El objetivo ha sido crear un espacio activista de cooperación para compartir proyectos de intervención e investigación que innovasen y tuvieran compromiso con el territorio, partiendo del conflicto que produce el pelo/cabello asociado a “raza” y ésta al poder, triangulación extrapolable a otros sures de fuerte evidencia sociocultural en el impacto de la acción (anti)racista.

Si el pelo ha sido comprendido históricamente como una cualidad determinante de la femineidad, ¿qué ocurre cuando este es empleado como materia prima para subvertir la norma? Desde una mirada feminista e interseccional, este trabajo indaga en las discursividades estéticas que desata el uso del cabello en propuestas artísticas contemporáneas. Intentaremos durante el análisis bucear en las posibles enunciaciones que agencia el pelo como recurso poético, dando cuenta así del carácter político que encarna este vestigio corporal. Se toman para ello tres obras latinoamericanas: las performances Bombril de Priscila Razende (2018) y Extensión de Regina Galindo (2018), y el libro de artista Corpus II de Jessica Sandoval (2021).

Hirsutism is defined as the excessive growth of terminal hair in a typically masculine pattern in women, affects around 5 to 10% and has a great psychological impact, causing problems of anxiety or depressive disorder; the etiology of this manifestation is very diverse, the most frequent being the ovarian cause, derived from polycystic ovary syndrome, other causes are congenital adrenal, neoplastic or secondary to drugs, so it represents not only an aesthetic problem, but also a manifestation of a major disease. The approach to patients, in addition to physical, is biochemical and includes the determination of testosterone levels, and screening for metabolic syndrome, while the treatment varies from mechanical and chemical removal, to laser or pulsed light, in order to improve aesthetics; and pharmacological treatment in order to cure the underlying disease; in the management of hirsutism, it is always important to evaluate the patient's expectations and consider the psychological impact, since all therapies have an onset of effect around six months after starting treatment. [ABSTRACT FROM AUTHOR]

Translation of the genetic code occurs in a cycle where ribosomes engage mRNAs, synthesize protein, and then disengage in order to repeat the process again. The final part of this process—ribosome recycling, where ribosomes dissociate from mRNAs—involves a complex molecular choreography of specific protein factors to remove the large and small subunits of the ribosome in a coordinated fashion. Errors in this process can lead to the accumulation of ribosomes at stop codons or translation of downstream open reading frames (ORFs). Ribosome recycling is also critical when a ribosome stalls during the elongation phase of translation and must be rescued to allow continued translation of the mRNA. Here we discuss the molecular interactions that drive ribosome recycling, and their regulation in the cell. We also examine the consequences of inefficient recycling with regards to disease, and its functional roles in synthesis of novel peptides, regulation of gene expression, and control of mRNA‐associated proteins. Alterations in ribosome recycling efficiency have the potential to impact many cellular functions but additional work is needed to understand how this regulatory power is utilized. [ABSTRACT FROM AUTHOR]

This article argues that hair modification by Black males in Latin America is both a resistance and reinscription of white cultural hegemony. Using the films Pelo malo (2013), by Mariana Rondón, and La playa D.C. (2012), by Juan Andrés Arango García, I demonstrate how socially constructed notions of race and masculinity imposed on Black males are both reproduced and resisted as natural survival mechanisms. While Pelo malo's Junior is ultimately defeated by social expectations that subjugate Blackness, La playa D.C.'s Tomás triumphs in socially oppressive systems and becomes a barber through his hair. By evaluating the two films together, this article shows how hair for Black males can be both an object of oppression and a source of pride. In this examination, we see how Black males straddle an in-between existential reality that pushes against the one-dimensional subjectivity often imposed by hegemonic identity rhetoric. In the end, this analysis exposes how Black men use hair to dismantle racially imposed subjugations and masculinist definitions in order to decolonize toxic constructs of Blackness and manhood. [ABSTRACT FROM AUTHOR]

Cicatricial alopecias are a group of hair disorders linked by the potential permanent loss of scalp hair follicles in involved areas. The primary cicatricial alopecias are the result of a direct inflammatory destruction towards the epithelium and the terminal hair of the follicular unit. The second part of this article reviews clinical features, histology, dermoscopy, management, and treatment of neutrophilic primary cicatricial alopecias (folliculitis decalvans and dissecting cellulitis) and mixed primary cicatricial alopecias (acne necrotica, acne keloidalis, and erosive pustular dermatosis). [ABSTRACT FROM AUTHOR]

Differentiation of the embryonic stem cells (ESCs) is regulated by a variety of different signaling pathways. Genetic depletion of murine Pelota gene (Pelo) leads to early embryonic lethality. Here, we aimed at determining the embryonic stage and deciphering the dysregulated signaling pathways affected upon Pelo deletion. We found that development of PELO‐null embryos is perturbed between the embryonic days E4.5 and E5.5, at which first differentiation process of ESCs takes place. Molecular analysis revealed enhanced activity of phosphoinositide 3‐kinase–protein kinase B/ AKT (PI3K‐PKB/AKT) signaling, but nuclear accumulation of forkhead box O1 (FOXO1), and upregulation of the pluripotency‐related gene, Oct4, in mutant ESCs cultured under differentiation condition. Despite increased levels of nuclear β‐catenin in PELO‐null ESCs as a result of decreased activity of glycogen synthase kinase‐3β, the activity of the canonical wingless (Wnt)/β‐catenin/T‐cell factor (TCF) was significantly attenuated as judged by the promoter reporter assay, downregulated Wnt/β‐catenin target genes, and impaired cell proliferation. Interestingly, we demonstrated an increased binding of β‐catenin to FOXO1 in PELO‐mutant ESCs cultured under differentiation condition that could explain, on one side, the nuclear accumulation of FOXO1 protein and hence persistent pluripotency of PELO‐mutant ESCs, and on the other side, the dysregulated transcriptional activity of β‐catenin/TCF and therefore attenuated PELO‐null ESC self‐renewal. Taken together, our results strongly suggest that PELO deletion averts ESC differentiation through promoting FOXO1/β‐catenin binding with subsequent dysregulation of FOXO1 and canonical β‐catenin/TCF signaling pathways. [ABSTRACT FROM AUTHOR]

Las enfermedades parasitarias gastrointestinales en ovinos limitan la productividad, predisponen al inicio de otras etiologías, hasta la muerte, además se reflejan en costos de producción. Esta investigación fue realizada en Betulia, Santander, Colombia, su objetivo fue determinar la presencia de parásitos gastrointestinales en ovinos de pelo, al suministrar un suplemento una vez por día durante 21 días con fruto de palma, mediante la toma de muestras fecales los días 0-7-14 y 21, determinación parasitaria a través de técnica de flotación. Dividiendo la población en dos tratamientos de 10 ovinos adultos cada uno, al Tratamiento 1 se les suministró un suplemento con inclusión al 30% de Fruto de Palma, al Tratamiento 2 se les suministró un suplemento con inclusión del 40% de Fruto de Palma. Las muestras se procesaron en laboratorio LACLIVET en Barrancabermeja. Los resultados se sometieron a análisis de varianza con Microsoft Excel® 2013 con un intervalo de confianza de 95% y 5% de error, este análisis determinó que no existen diferencias significativas entre los tratamientos con respecto a los parásitos encontrados en dichos muestreos coprológicos. En las muestras procesadas se encontraron cuatro tipos de parásitos gastrointestinales, Strongyloides spp. (12), Paramphistomum spp. (10), Haemonchus spp. (18), Eimeria spp. (10). Finalmente en 33 de 80 muestras procesadas no se observaron parásitos gastrointestinales representando el 41% del total. Se determinó que al suministrar suplementos con inclusión de fruto de palma al 30% y al 41%, no hay diferencias significativas en los tratamientos 1 y 2 sobre la presentación de parásitos gastrointestinales en los ovinos evaluados.

Hair is an element that has been present in human evolution since time immemorial. The excessive growth of hair on the body starts from a historical reality, since they are the result of real diseases: hypertrichosis and hirsutism. Taking as a starting point the image of the bearded women, we will address the stereotypes about female sexuality, the ideals of beauty and the definition of gender that are taken up in the creation of contemporary works of art in which the absence or presence of hair and its body location is a decisive element. [ABSTRACT FROM AUTHOR]

Copyright of Goya is the property of Fundacion Lazaro Galdiano and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Ardeola is the property of Sociedad Espanola de Ornitologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Innotec is the property of Laboratorio Tecnologico del Uruguay and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Conservar Património is the property of Associacao Profissional de Conservadores-Restauradores de Portugal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Proponemos un acercamiento, analítico y comparativo, al movimiento desde una serie de obras organizadas como pictogramas visuales que argumentan la sintaxis de la representación desde el empleo de la imagen fotográfica, el dibujo y la palabra. Por un lado, en el pictograma fotográfico, el movimiento no sólo aparece como inscripción de un recorrido físico, recogido a través de una serie de imágenes fotosecuenciadas, o por la acción de capturar e ir tras el objetivo, sino también como un trayecto ideológico organizado a través del orden semiótico de la propia imagen fotográfica y del encuadre como estructurador de la mirada. Por otro lado, en el pictograma dibujado, el movimiento es iniciado por el propio acto de marcar y manchar el papel. El dibujo es interpretado como una acción que establece relaciones escénicas y temporales tanto con el espacio real y físico como con la psique. Las obras que han motivado este análisis tituladas La Imagen Negada, Affidamento y Correspondencias persiguen poner en pie una gramática dinámica de la representación. With this article I propose an analytical and comparative approach to movement based on a series of works organised as visual sequences which argue for the syntax of representation using the photographic image, drawing and words. On the one hand, in the sequences of photos, movement does not only appear as an inscription of a physical route, recorded by a fluency of photography images or by the action of capturing and pursuing the objective, but also as an ideological trajectory organised through the semiotic order of the photographic image itself and of the framing as the element that structures the gaze. And on the other hand, in the drawn pictogram, movement is initiated by the very act of marking and staining the paper. Drawing is interpreted as an action that establishes scenic and temporary relations both with the real, physical space and with the psyche. The works that motivated this analysis, entitled, Affidamento, Posiciones, La imagen negada and Correspondencias, aim to establish a dynamic grammar of representation.

Copyright of Journal of Optometry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Arquivos de Ciências Veterinárias e Zoologia da Unipar is the property of Associacao Paranaense de Ensino e Cultura and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

NOD-like receptors (NLRs) are pattern recognition receptors for diverse innate immune responses. Self-oligomerization after engagement with a ligand is a generally accepted model for the activation of each NLR. We report here that a catalyzer was required for NLR self-oligomerization. PELO, a well-known surveillance factor in translational quality control and/or ribosome rescue, interacted with all cytosolic NLRs and activated their ATPase activity. In the case of flagellin-initiated NLRC4 inflammasome activation, flagellin-bound NAIP5 recruited the first NLRC4 and then PELO was required for correctly assembling the rest of NLRC4s into the NLRC4 complex, one by one, by activating the NLRC4 ATPase activity. Stoichiometric and functional data revealed that PELO was not a structural constituent of the NLRC4 inflammasome but a powerful catalyzer for its assembly. The catalytic role of PELO in the activation of cytosolic NLRs provides insight into NLR activation and provides a direction for future studies of NLR family members. [Display omitted] • PELO interacts with all cytosolic NLRs and potentiates their ATPase activity • Activation of the ATPase by PELO is required for the oligomeric assembly of NLRs • PELO controls the activation of NLRs, including NLRP3 and NLRC4 • PELO's function in NLR activation is independent of its function in ribosome rescue The ATPase activity of NLRs is essential for driving their oligomeric assembly and activation, yet it is poorly understood. Wu et al. reveal that the ribosome-rescuer PELO catalyzes self-oligomerization of all cytosolic NLRs via potentiating their ATPase activity, thus controlling both inflammasomal and non-inflammasomal NLR activation. [ABSTRACT FROM AUTHOR]

O objetivo do trabalho foi avaliar as características morfológicas como densidade numérica e espessura do pelame e comprimento dos pelos de vacas Holandesas predominantemente negras, puras por cruza em lactação na região de Montes Claros no norte de Minas Gerais. O estudo foi conduzido em duas fases, A: julho/agosto e B: outubro/novembro de 2010, utilizando 12 fêmeas Holandesas em lactação, puras por cruza de pelame predominante negro. Foram medidas as características de densidade numérica (nº pelos/cm²), espessura (mm), comprimento (mm) e a temperatura da superfície do pelame (TPE). Os resultados mostraram que o pelame foi menos denso, com pelos mais curtos na fase B, no entanto a espessura não variou entre as duas fases. No período em que ocorreu maior densidade numérica houve menor TPE. As características do pelame das vacas Holandesas puras por cruza observadas indicam uma boa adequação às condições ambientais da região em estudo.

The present report describes the clinical and pathological findings related to diffuse heterotopic hairs associated with pseudo-placentational endometrial hyperplasia in a canine uterus. Macroscopically, the uterus was intensely enlarged and thicker, and the endometrial surface was irregular and covered with black hairs similar to the hairs of the bitch. Histologically, heterotopic hairs associated with pseudo-placentational endometrial hyperplasia were observed.

A mutation in the gene coding for the ryanodine receptor 1 (RYR1), also known as halothane (hal) gene or swine stress gene, is associated to the porcine stress syndrome (PSS). Detection of the mutation is normally accomplished by PCR amplification of an 81bp fragment of the hal gene, followed by digestion with the HhaI restriction endonuclease. Wild-type allele (N) is cut in two fragments, whereas the mutant allele (n) is not digested by the restriction enzyme. Electrophoresis of the digested DNA on agarose gel and ethidium bromide staining allows the reading of the result. The correct interpretation is difficult due to the small size of the DNA fragments. In this study we designed a new set of primers for amplification of a 144bp fragment that facilitates the reading of the result. In addition, we optimized the PCR reaction to allow amplification from a single hair bulb, added directly into the PCR mix without previous treatment. This improved method was used to genotype 165 sows and boars used in a breeding program. Forty-nine percent of the animals had the NN genotype, whereas 50% were Nn and only 1% was nn.Uma mutação no gene que codifica o receptor ryanodine 1 (RYR1), também conhecido como gene do halotano (hal) ou gene do estresse suíno, está associada à Síndrome do Estresse Suíno (PSS). A mutação é geralmente detectada por PCR, a partir da amplificação de um fragmento de 81pb do gene hal, seguida por digestão com a endonuclease de restrição HhaI. O alelo normal (N) é cortado em dois fragmentos, enquanto que o alelo mutado (n) não é digerido pela enzima de restrição. A eletroforese do DNA digerido em gel de agarose corado com brometo de etídio permite a leitura do resultado. A interpretação correta é difícil devido ao pequeno tamanho dos fragmentos. Neste estudo, foi projetado um novo par de iniciadores para a amplificação de um fragmento de 144pb, o que facilita a leitura do resultado. Adicionalmente, foi otimizada a reação de PCR para permitir a amplificação a partir de um único bulbo capilar, acrescentado diretamente na mistura de PCR, sem tratamento prévio. Esse método foi usado para genotipar 165 reprodutores utilizados em granjas produtoras de matrizes. Quarenta e nove porcento dos animais apresentaram genótipo NN, 50% Nn e apenas 1% nn.

Se determinó la variación del pelo de guardia dorsal entre individuos de la misma especie y se comparó la variación de un individuo en diferentes regiones. Se midió la longitud total y diámetro de la médula, además se determinó el patrón de tonalidad y tipo de médula. En la comparación intraespecífica se caracterizaron 530 pelos de guardia dorsales de 53 organismos. A pesar de las variaciones en la longitud y diámetro de la médula, puede realizarse una identificación exitosa de los organismos en un plano específico utilizando la guía de identificación de mamíferos terrestres a partir del pelo de guardia, excepto para Canis latrans y Liomys irroratus. En la comparación individual se describieron 560 pelos de guardia de 14 especies. Se encontraron diferencias en la longitud total del pelo, en el diámetro de la médula y en la coloración; el único carácter que permaneció constante fue la médula.

Recientes excavaciones en el yacimiento argárico de Castellón Alto con motivo de los trabajos de acondicionamiento para su visita publica han permitido descubrir una sepultura con restos humanos momificados en su interior. La sepultura de tipo covacha se encontraba sellada por tablones de madera y un muro de mampostería. En el interior aparecieron un individuo adulto y un infantil que conservan restos de pelo y piel. El ajuar se compone de varias vasijas cerámicas, un puñal, una azuela con mango de madera y adornos en metal, así como restos de lino y posiblemente lana.

El mercurio (Hg) es considerado un contaminante global por su alta toxicidad y características fisicoquímicas que le permiten trasportarse a los diferentes compartimientos ambientales, bioacumularse y biomagnificarse en la cadena trófica. Existen numerosos sitios contaminados por mercurio entre el norte de Antioquia y el Sur de Bolívar debido a la explotación aurífera, en ellos viven mineros y sus familias, quienes consumen cantidades considerables de animales domésticos como gallinas, cerdos y patos, por lo que esta investigación tuvo por objeto evaluar la concentración de mercurio presente en animales domésticos en Mina Santa Cruz, Sur de Bolívar. Se tomaron 146 muestras biológicas procedentes del sitio de estudio, distribuidas en 39 muestras de pelo de Sus scrofa (cerdo) y 107 muestras de pluma, 91 en Gallus gallus (gallina) y 16 en Cairina moschata (pato); asimismo, se tomó un grupo de comparación en zona rural del municipio de Sincelejo de 10 individuos de las mismas especies, que no estaban expuestos al metal por actividades mineras y se determinó la concentración de mercurio total (HgT) por espectrofotometría de absorción atómica por vapor frío. Las concentraciones más altas de HgT se observaron en Sus scrofa, (8156,9 ± 882,2 ng/g peso seco), seguido de Gallus gallus (3391,9 ± 639,5 ng/g peso seco) y Cairina moschata (1426,5 ± 263,9 ng/g peso seco). El consumo de patos, gallinas y cerdos establecidos en Mina Santa Cruz, representan un riesgo importante a la salud pública, debido a las altas concentraciones acumuladas en sus organismos.

Arabic edition and the Spanish translation of an anonymous short scientific treatise, Dissertation on the hair, included in the miscellaneous manuscript nº 888 of the Royal Library of the Monastery of San Lorenzo de El Escorial, providing reasons for hair growth and significance in the body, differences between hair of men, women and children, and characteristics and qualities of people with curly, straight, blond or dark hair and capillary diseases. The whole manuscript consists of fourteen parts written by the same copyist in 170 folios under the general title of The book of medical and philosophical curiosities and utilities, covering several subjects from both branches of knowledge. [ABSTRACT FROM AUTHOR]

Análisis de mercurio en cabello fue realizado a 219 personas que habitan en la principal zona de minería del oro en Colombia, tomando 27 personas de la ciudad de Cartagena, como muestra Control. Para el análisis de los datos, la muestra estudiada se dividió de acuerdo con la ocupación de las personas, encontrándose concentraciones medias (±DE) de 5,23±5,78, 2,83±3,27, 2,40±2,02 y 1,33±0,74 µg/g de mercurio en cabello, para pescadores, mineros, personas dedicadas a otras actividades y grupo control respectivamente. De acuerdo con el análisis de varianza y el test de Newman Keuls, existe diferencia significativa (pHair mercury analysis was carried out on a sample of 219 people living in the main gold mining zone of Colombia, 27 inhabitante of Cartagena City being taken as control sample. For data analysis the sample was divided by occupation and the corresponding the hair mercury concentrations (mean ± SD) were found to be 5.23 ± 5.78, 2.83 ± 3.27, 2.4 ± 2.02 and 1.33 ±0.74 µg/g for fishermen, miners, people of various other activities and the control sample, respectively. According to variance analysis and the Newman Keuls test, there were significant differences (p

A displasia folicular canina é uma dermatopatia incomum caracterizada clinicamente por alopecia e alterações na qualidade da pelagem. Relata-se o caso de um cão, sem raça definida, 7 meses de idade, macho, levado à consulta por apresentar alopecia progressiva disseminada. O diagnóstico anátomo-clínico da displasia folicular canina do caso ora descrito foi estabelecido pelos dados colhidos na resenha e anamnese, achados do exame dermatológico e osteomuscular e confirmado pelas alterações histológicas dos fragmentos de pele biopsiados. Este artigo visa relatar um caso de displasia folicular canina e comparar com outros casos descritos na literatura, pois são esparsos as descrições na literatura brasileira.

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article discusses the results of a study that examined the association of diffuse heterotopic hairs with pseudo-placentational endometrial hyperplasia in a canine uterus. Results of macroscopic test showed an enlarged and thicker uterus while the endometrial surface was irregular and covered with black hairs similar to the hairs of the bitch. Histological findings confirmed the association between heterotopic hairs and pseudo-placentational endometrial hyperplasia.