Search

Your search keyword '"Pellegrino, Giovanni"' showing total 400 results
Start Over Author "Pellegrino, Giovanni"
400 results on '"Pellegrino, Giovanni"'

2. University and COVID-19: The Experience of the Academic Community of the Single-Cycle Master's Degree in Law of the University of Genoa

Author

Magarò, Patrizia, Accordino, Loic, Cugnetto, Davide, Gheorghe, Constantin, Keqi, Anduela, Laigueglia, Chiara, Luciani, Ludovica, Pellegrino, Giovanni, Scarola, Laura, Süto, Brigitta Tünde, and Valle, Margherita

Abstract

The article focuses on challenges and disruption in the higher education sector in Italy due to COVID-19 pandemic. The study explores the experience of the Single-Cycle Master's Degree in Law of the University of Genoa, especially taking into account students' perspective.

Published
2023
Full Text
View/download PDF

4. WHOCARES: data-driven WHOle-brain CArdiac signal REgression from highly accelerated simultaneous multi-Slice fMRI acquisitions

Author

Colenbier, Nigel, Marino, Marco, Arcara, Giorgio, Frederick, Blaise, Pellegrino, Giovanni, Marinazzo, Daniele, and Ferrazzi, Giulio

Subjects
Physics - Medical Physics
Abstract

Cardiac pulsation is a physiological confound of functional magnetic resonance imaging (fMRI) time-series that introduces spurious signal fluctuations in proximity to blood vessels. fMRI alone is not sufficiently fast to resolve cardiac pulsation. Depending on the ratio between the instantaneous heart-rate and the acquisition sampling frequency (1/TR, with TR being the repetition time), the cardiac signal may alias into the frequency band of neural activation. The introduction of simultaneous multi-slice (SMS) imaging has significantly reduced the chances of cardiac aliasing. However, the necessity of covering the entire brain at high spatial resolution restrain the shortest TR to just over 0.5 seconds, which is in turn not sufficiently short to resolve cardiac pulsation beyond 60 beats per minute. Recently, hyper-sampling of the fMRI time-series has been introduced to overcome this issue. While each anatomical location is sampled every TR seconds, the time between consecutive excitations is shorter and thus adequate to resolve cardiac pulsation. In this study, we show that it is feasible to temporally and spatially resolve cardiac waveforms at each voxel location by combining a dedicated hyper-sampling decomposition scheme with SMS. We developed the technique on 774 healthy subjects selected from the Human Connectome Project (HCP) and validated the technology against the RETROICOR method. The proposed approach, which we name Data-driven WHOle-brain CArdiac signal REgression from highly accelerated simultaneous multi-Slice fMRI acquisitions (WHOCARES), is fully data-driven, does not make specific assumptions on cardiac pulsatility, and is independent from external physiological recordings so that the retrospective correction of fMRI data becomes possible when such measurements are not available. WHOCARES is freely available at https://github.com/gferrazzi/WHOCARES.

Published
2022
Full Text
View/download PDF

15. Decompressive hemicraniectomy in patients with malignant middle cerebral artery infarction: A real-world study

Author

Pilato, Fabio, Pellegrino, Giovanni, Calandrelli, Rosalinda, Broccolini, Aldobrando, Della Marca, Giacomo, Frisullo, Giovanni, Morosetti, Roberta, Profice, Paolo, Brunetti, Valerio, Capone, Fioravante, D'Apolito, Gabriella, Quinci, Vincenzo, Albanese, Alessio, Mangiola, Annunziato, Marchese, Enrico, Pompucci, Angelo, and Di Lazzaro, Vincenzo

Published
2022
Full Text
View/download PDF

20. Disrupting the epileptogenic network with stereoelectroencephalography‐guided radiofrequency thermocoagulation

Author

Kreinter, Hellen, primary, Espino, Poul H., additional, Mejía, Sonia, additional, Alorabi, Khalid, additional, Gilmore, Greydon, additional, Burneo, Jorge G., additional, Steven, David A., additional, MacDougall, Keith W., additional, Jones, Michelle‐Lee, additional, Pellegrino, Giovanni, additional, Diosy, David, additional, Mirsattari, Seyed M., additional, Lau, Jonathan, additional, and Suller Marti, Ana, additional

Published
2024
Full Text
View/download PDF

24. Altered spread of waves of activities at large scale is influenced by cortical thickness organization in temporal lobe epilepsy: a magnetic resonance imaging–high-density electroencephalography study

Author

Duma, Gian Marco, primary, Pellegrino, Giovanni, additional, Rabuffo, Giovanni, additional, Danieli, Alberto, additional, Antoniazzi, Lisa, additional, Vitale, Valerio, additional, Scotto Opipari, Raffaella, additional, Bonanni, Paolo, additional, and Sorrentino, Pierpaolo, additional

Published
2023
Full Text
View/download PDF

33. The impact of ROI extraction method for MEG connectivity estimation: practical recommendations for the study of resting state data

Author

Brkić, Diandra, primary, Sommariva, Sara, additional, Schuler, Anna-Lisa, additional, Pascarella, Annalisa, additional, Belardinelli, Paolo, additional, Isabella, Silvia L., additional, Di Pino, Giovanni, additional, Zago, Sara, additional, Ferrazzi, Giulio, additional, Rasero, Javier, additional, Arcara, Giorgio, additional, Marinazzo, Daniele, additional, and Pellegrino, Giovanni, additional

Published
2023
Full Text
View/download PDF

34. N°331 – Evaluating the effects of the first anti seizure medication on the EEG pattern complexity of Temporal Lobe Epilepsy by means of fractal analysis

Author

Ferreri, Florinda, primary, Maatta, Sara, additional, Meervala, Esa, additional, Pellegrino, Giovanni, additional, Luisi, Concetta, additional, Dainese, Filippo, additional, Kassabian, Benedetta, additional, Pellegrino, Luciano, additional, de Nardi, Gianluigi, additional, Grego, Alberto, additional, D'onofrio, Valentina, additional, Corbetta, Maurizio, additional, and Porcaro, Camillo, additional

Published
2023
Full Text
View/download PDF

37. High-frequency transcranial alternating current stimulation matching individual frequency of somatosensory evoked high-frequency oscillations can modulate the somatosensory system through thalamocortical pathway.

Author

Cruciani, Alessandro, Pellegrino, Giovanni, Todisco, Antonio, Motolese, Francesco, Sferruzzi, Marco, Norata, Davide, Santoro, Francesca, Musumeci, Gabriella, Rossi, Mariagrazia, Pilato, Fabio, Lazzaro, Vincenzo Di, and Capone, Fioravante

Published
2024
Full Text
View/download PDF

40. Hierarchical Bayesian modeling of the relationship between task-related hemodynamic responses and cortical excitability

Author

Cai, Zhengchen, Pellegrino, Giovanni, Lina, Jean-Marc, Benali, Habib, Grova, Christophe, Cai, Zhengchen, Pellegrino, Giovanni, Lina, Jean-Marc, Benali, Habib, and Grova, Christophe

Abstract

Investigating the relationship between task-related hemodynamic responses and cortical excitability is challenging because it requires simultaneous measurement of hemodynamic responses while applying noninvasive brain stimulation. Moreover, cortical excitability and task-related hemodynamic responses are both associated with inter-/intra-subject variability. To reliably assess such a relationship, we applied hierarchical Bayesian modeling. This study involved 16 healthy subjects who underwent simultaneous Paired Associative Stimulation (PAS10, PAS25, Sham) while monitoring brain activity using functional Near-Infrared Spectroscopy (fNIRS), targeting the primary motor cortex (M1). Cortical excitability was measured by Motor Evoked Potentials (MEPs), and the motor task-related hemodynamic responses were measured using fNIRS 3D reconstructions. We constructed three models to investigate: (1) PAS effects on the M1 excitability, (2) PAS effects on fNIRS hemodynamic responses to a finger tapping task, and (3) the correlation between PAS effects on M1 excitability and PAS effects on task-related hemodynamic responses. Significant increase in cortical excitability was found following PAS25, whereas a small reduction of the cortical excitability was shown after PAS10 and a subtle increase occurred after sham. Both HbO and HbR absolute amplitudes increased after PAS25 and decreased after PAS10. The probability of the positive correlation between modulation of cortical excitability and hemodynamic activity was 0.77 for HbO and 0.79 for HbR. We demonstrated that PAS stimulation modulates task-related cortical hemodynamic responses in addition to M1 excitability. Moreover, the positive correlation between PAS modulations of excitability and hemodynamics brought insight into understanding the fundamental properties of cortical function and cortical excitability.

Published
2023

47. Sensorimotor integration within the primary motor cortex by selective nerve fascicle stimulation

Author

Ranieri, Federico, Pellegrino, Giovanni, Ciancio, Anna Lisa, Musumeci, Gabriella, Noce, Emiliano, Insola, Angelo, Diaz Balzani, Lorenzo Alirio, Di Lazzaro, Vincenzo, and Di Pino, Giovanni

Subjects
sensorimotor cortical circuits, Physiology, Movement, Motor Cortex, primary somatosensory cortex (S1), Somatosensory Cortex, Evoked Potentials, Motor, Transcranial Magnetic Stimulation, Electric Stimulation, primary motor cortex (M1),  primary somatosensory cortex (S1), Evoked Potentials, Somatosensory, &nbsp, selective intraneural sensory stimulation, Humans
Abstract

The integration of sensory inputs in the motor cortex is crucial for dexterous movement. We recently demonstrated that a closed-loop control based on the feedback provided through intraneural multichannel electrodes implanted in the median and ulnar nerves of a participant with upper limb amputation improved manipulation skills and increased prosthesis embodiment. Here we assessed, in the same participant, whether and how selective intraneural sensory stimulation also elicits a measurable cortical activation and affects sensorimotor cortical circuits. After estimating the activation of the primary somatosensory cortex evoked by intraneural stimulation, sensorimotor integration was investigated by testing the inhibition of primary motor cortex (M1) output to transcranial magnetic stimulation, after both intraneural and perineural stimulation. Selective sensory intraneural stimulation evoked a low-amplitude, 16 ms-latency, parietal response in the same area of the earliest component evoked by whole-nerve stimulation, compatible with fast-conducting afferent fibre activation. For the first time, we show that the same intraneural stimulation was also capable of decreasing M1 output, at the same time range of the short-latency afferent inhibition effect of whole-nerve superficial stimulation. The inhibition generated by the stimulation of channels activating only sensory fibres was stronger than that due to intraneural or perineural stimulation of channels activating mixed fibres. We demonstrate in a human subject that the cortical sensorimotor integration inhibiting M1 output previously described after the experimental whole-nerve stimulation is present also with a more ecological selective sensory fibre stimulation. KEY POINTS: Cortical integration of sensory inputs is crucial for dexterous movement. Short-latency somatosensory afferent inhibition of motor cortical output is typically produced by peripheral whole-nerve stimulation. We exploited intraneural multichannel electrodes used to provide sensory feedback for prosthesis control to assess whether and how selective intraneural sensory stimulation affects sensorimotor cortical circuits in humans. Activation of the primary somatosensory cortex (S1) was explored by recording scalp somatosensory evoked potentials. Sensorimotor integration was tested by measuring the inhibitory effect of the afferent stimulation on the output of the primary motor cortex (M1) generated by transcranial magnetic stimulation. We demonstrate in humans that selective intraneural sensory stimulation elicits a measurable activation of S1 and that it inhibits the output of M1 at the same time range of whole-nerve superficial stimulation.

Published
2022
Full Text
View/download PDF

50. Validating MEG source imaging of resting state oscillatory patterns with an intracranial EEG atlas

Author

Afnan, Jawata, primary, Ellenrieder, Nicolás von, additional, Lina, Jean-Marc, additional, Pellegrino, Giovanni, additional, Arcara, Giorgio, additional, Cai, Zhengchen, additional, Hedrich, Tanguy, additional, Abdallah, Chifaou, additional, Khajehpour, Hassan, additional, Frauscher, Birgit, additional, Gotman, Jean, additional, and Grova, Christophe, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results