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Abstract To analyse the effectiveness of resistance training on secondary sarcopenia, we conducted a meta-analysis to elucidate the effects of resistance training (RT) on muscle strength (handgrip strength [HGS]), muscle mass (Skeletal muscle mass index [SMI]), and physical function (Gait speed [GS]) in patients with secondary sarcopenia. All studies published between 2015 and January 2024 on the effects of resistance training on patients with secondary sarcopenia were retrieved from 6 electronic databases: PubMed, Web of Science Core Collection, Embase, the Cochrane Library, the China National Knowledge Infrastructure (CNKI) Core journals and the Wanfang Database. Two researchers independently extracted and evaluated studies that met the inclusion and exclusion criteria. Finally, 12 randomized controlled trials were included. Pooled analyses of baseline data and results were performed using Review Manager 5.3 with standardized mean variance (SMD) and random effects model. The study included 12 randomized controlled trials involving 639 patients (mean age 57.28 ± 2.66 to 79.6 ± 5.4 years). There are five types of complications among the patients: obesity, type 2 diabetes, Alzheimer’s disease, hemodiaysis, and pancreatic cancer. Compared with the control group, RT effectively improved HGS [SMD = 2.47, 95% CI (1.50, 3.43), p

Introduction Sarcopenia is a condition that occurs more frequently in older adults. Although many types of exercise have been used in the treatment of sarcopenia, few studies have been conducted on different interventional environments for sarcopenia. The purpose of this study is to investigate the effects of aquatic exercise and land-based exercise on the body composition and function of participants with sarcopenia.Methods and analysis This randomised, controlled, single-blinded trial will enrol 45 participants (≥ 65 years) following the diagnostic criteria set by the Asian Working Group for Sarcopenia 2019. Participants will be randomised and assigned to one of three groups (aquatic exercise group, land-based exercise group and control group). Assessments will be conducted four times: initially (before intervention), after 8 weeks (intermediate), after 16 weeks (final) and 16 weeks after the end of intervention (follow-up). The primary outcomes are appendicular skeletal muscle index and handgrip strength, while the secondary outcomes include the Short Physical Performance Battery, 6-minute walk test and the Chinese version of the 36-item short-form of health-related quality of life.Ethics and dissemination Ethics approval was obtained from the Ethics Committee of Chengdu Sport University, with permission number CDSUEC2023-125. This study has been registered with the Chinese Clinical Trial Registry (ChiCTR2300077457). All participants will provide written informed consent.Trial registration number Chinese Clinical Trial Registry ChiCTR2300077457.

Quantum metrology, such as quantum phase estimation, can surpass classical sensing limits, reaching the Heisenberg‐scaling precision. So far, this kind of metrology has been thought to be only implementable with the quantum systems, which, however, are fragile to environmental noise and hardly contribute to the practical detections. Herein, it is demonstrated both theoretically and experimentally that the parameter encoded by the optical phase can also be estimated at the Heisenberg scaling in classical optics. Inspired by the quantum‐entanglement‐enhanced sensing scheme, the estimation is performed by using classically correlated beams as probes, and obtaining the probes readout after their interaction with the target system. Because the correlated beams considered are spatially separable, a distributed phase estimation scheme is given, which can sense the linear combinations of the phase shifts induced by distinct systems. The results of our experiments show an error reduction up to 3.89 dB below the classical limit when the correlated beam number for probing is 6, approaching the Heisenberg limit. Compared with quantum strategies, the proposal shows a better robustness against the environmental disturbance and keeps their performances even when the correlated beam number is relatively large. Hence, it indicates promising practical applications in the future.

PVA‐BB/GO‐Fe3+/agar hydrogels (BB is configured by 1:1 configuration of 0.04 mol L−1 boric acid solution and 0.04 mol L−1 borax solution) are designed with excellent mechanical and electrical properties due to their triple cross‐linked network, and they maintain stable performance in various tests, which is sufficient to support the use of hydrogels in multiple scenarios. Meanwhile, the tension responsiveness of the PVA‐BB/GO‐Fe3+/agar hydrogel allows it to rapidly transmit signal changes upon tension changes. Finally, maintaining increased energy dissipation and strength enhancement during the loading–unloading cycle provides the possibility of long, stable operation. In summary, it is believed that PVA‐BB/GO‐Fe3+/agar hydrogel has significant potential in the field of flexible sensors and is expected to be fabricated as a sensor for motion monitoring.

With an increase in rocket motor thrust, the thermal loads on the launch platform by the impingement exhaust jet are significantly increased, this poses serious safety risks to rocket launch. Therefore, a water cooling system should be designed to improve the thermal environment. In this study, the cooling effects of a water spray system with different injection velocities were analyzed through numerical simulation of high precision, and the afterburning effect of the exhaust gas was also considered to improve the calculation accuracy. The results showed that afterburning primarily occurred in the mixing layer, leading to a larger high-temperature region in the impingement plate. The water cooling system realized thermal protection for the launch platform, which was achieved by decreasing the temperature and velocity of impingement jet. With an increase in the aqueous jet velocity, a more significant cooling effect of the water spray system was obtained. However, the guiding performance of the deflector was decreased owing to the large amount of water vapor formed in the channel. It is suggested that the water spray system design should adopt an aqueous jet velocity of 20 m/s as a parameter after considering the cooling effect and guiding performance of the deflector.

This study aims to understand the influence of chlorophyll fluorescence parameters on the yield of winter wheat in some areas of China. Nitrogen (N) application is believed to improve photosynthesis in flag leaf, which ultimately increases the final yield. The experiment was conducted in the wheat experimental base of Shanxi Agricultural University in Taigu, Shanxi Province, China; before sowing, four N application rates were set—N0, N120, N150, and N210 kg ha–1 of the Yunhan-20410 variety from 2019 to 2022. The results from different parameters of research showed that the organic manure partial substitution for chemical fertilizer increased post-anthesis N uptake by 16.4 and 81.4%, thus increasing the post-anthesis photosynthetic capacity and delaying leaf senescence. N150 treatment can improve dry matter (DM) accumulation, thus promoting the increase of the yield. The maximum net photosynthesis PN value of the booting stage and flowering stage indicated that nitrogen application could significantly improve the photosynthetic rate of wheat leaves, among which medium nitrogen treatment had the most significant promoting effect. The single-photon avalanche diode (SPAD) value of the leaf of wheat in each treatment increased rapidly in a small range from the jointing stage to the booting stage, respectively. The grain yield under N fertilizer partial substitution for N fertilizer treatment increased by 23%. According to the different significance test, the effects of nitrogen application rate on net photosynthesis PN of winter wheat were extremely significant at all growth stages, indicating that changing the population distribution mode and nitrogen level could effectively improve leaf photosynthetic performance and that N150 level was the best.

The current study was designed to investigate the best sowing method that encourages dry matter accumulation to increase dryland wheat yield, grain quality, and protein content. Three different seeding methods were applied: (I) wide-space sowing (WSS), (II) furrow sowing, and (III) drill sowing. Two nitrogen levels, namely low nitrogen (N1) and high nitrogen (N2), were also applied, and the pure nitrogen was 150 kg ha−1 and 210 kg ha−1, respectively. Wide-space sowing significantly increased the ears and yield production, the maximum, and average grain-filling rate while furrow sowing delayed the disappearance of the population after anthesis, increased the duration of grain filling, and then significantly increased the number of spikes and the 1000-grain weight increased, respectively. Drill sowing compared to wide-space sowing significantly increased the content of nitrogen in the grain of the nitrogen harvest index, and it increased the content of protein and the yield of protein, respectively. In addition, the grain yield and protein yield of wide-precision sowing were significantly higher than that of trench sowing. Our findings suggest that wide-space sowing was beneficial for increasing water consumption during the growth period, increasing the tiller dynamics, improving the plant dry matter quality, and increasing the grain protein.

The liquid rocket propellant burns inadequately in the combustion chamber; therefore, the exhaust gas reacts with oxygen and the heat that was generated, which in turn affects the thermal environment. By using finite-rate chemical kinetics and discrete ordinates method, the calculation model for the four-engine rocket exhaust flowfield is established, and numerically investigates the afterburning effect on the thermal environment of the engine exhaust plume under different altitudes. The results show that the afterburning reactions have little influence on the Mach number exhaust flow, and the difference between the peak temperatures of reacting and non-reacting flows is less than 5%. However, a significant increase in temperature of the mixing layer can be found, and the afterburning effect on the thermal environment reduces with increases in the flight altitude. At the same altitude, the temperature increment of the reacting flow in the far-field region is higher than that of the near-field region. Moreover, as the flight altitude increases from 15 to 35 km, the increase of the rocket base heat flux caused by the afterburning can vary from 9.4% to 2.7%. The results provide a theoretical basis for the designing of the thermal protection systems of multi-engine rockets.

A designed cryogenic upper stage adopted liquid hydrogen and liquid oxygen (LH2/LO2) as an aerospace propellant. During a zero-gravity coast period in space, the wall heat leakage into the delivery tube could induce liquid propellant evaporation and two-phase flow phenomenon, so that a bubble discharge operation must be employed prior to engine restart. In this study, a CFD approach was utilized to numerically study the bubble discharge behaviors inside the LH2 delivery tube of the upper stage. The bubble motion properties under two different schemes, including positive acceleration effect and circulation flow operation, were analyzed and discussed. The results showed that the boiled hydrogen bubbles could increase to the size of the tube inner diameter and distribute randomly within the entire tube volume, and that, in order for the bubble to spill upward under the acceleration effect, a higher acceleration level than the needed value of acquiring liquid–vapor separation inside the propellant tank should be provided. When creating an acceleration level of 10−3 g0, most of the bubbles could spill upward within 700 s. Significantly, the bubbles could not be completely expelled in the created acceleration condition since a number of small bubbles always stagnate in the bulk liquid region. In the circulation flow operation, the gas volume reduction was mainly attributed to two mechanisms: the vapor condensation effect; and bubble discharge effect. For the case with a circulation flow rate of 0.2 kg/s, a complete bubble discharge purpose was reached within 820 s, while a large bubble stagnation in the spherical distributor occupied a remarkable proportion of the total time. In addition, both the liquid flow rate and liquid subcooling exert important effects on bubble performance. When applying a high circulation flow, the gas volume reduction is mainly due to the inertial effect of liquid flow, but the bubble stagnation in the spherical distributor still affects the total discharge time. The liquid subcooling influence on the gas volume reduction is more significant in smaller circulation flow cases. Generally, the present study provides valuable conclusions on bubble motions inside a LH2 delivery tube in microgravity, and the results could be beneficial to the sequence design of engine restart for the cryogenic upper stage.

How magnetism affects the Seebeck effect is an important issue of wide concern in the thermoelectric community but remains elusive. Based on a thermodynamic analysis of spin degrees of freedom on varied d-electron-based ferromagnets and antiferromagnets, we demonstrate that in itinerant or partially itinerant magnetic compounds there exists a generic spin contribution to the Seebeck effect over an extended temperature range from slightly below to well above the magnetic transition temperature. This contribution is interpreted as resulting from transport spin entropy of (partially) delocalized conducting d electrons with strong thermal spin fluctuations, even semiquantitatively in a single-band case, in addition to the conventional diffusion part arising from their kinetic degrees of freedom. As a highly generic effect, the spin-dependent Seebeck effect might pave a feasible way toward efficient “magnetic thermoelectrics.” Public summary: • Magnetism can offer a significant contribution to thermoelectricity • A generic Seebeck effect exists in magnetic conductors as a result of transport spin entropy of delocalized d electrons • The magnetocaloric effect and the Seebeck effect are thermodynamically correlated with each other

Charge transport of topological semimetals is the focus of intensive investigations because of their nontrivial band topology. Heat transport of these materials, on the other hand, is largely unexplored and remains elusive. Here, we report on an observation of unprecedented, giant magnetic quantum oscillations of thermal conductivity in the prototypical Weyl semimetal TaAs. The oscillations are antiphase with the quantum oscillating electronic density of states of a Weyl pocket, and their amplitudes amount to 2 orders of magnitude of the estimation based on the Wiedemann-Franz law. Our analyses show that all the conventional heat-transport mechanisms through diffusions of propagating electrons, phonons, and electron-hole bipolar excitations are far inadequate to account for these phenomena. Taking further experimental facts that the parallel field configuration favors much-higher magnetothermal conductivity, we propose that the newly proposed chiral zero sound provides a reasonable explanation to these exotic phenomena. More work focusing on other topological semimetals along the same line is badly called for.

BACKGROUND: Evidence suggested that abiotic airborne exposures may be associated with changes in body composition. However, more evidence is needed to identify key pollutants linked to adverse health effects and their underlying biomolecular mechanisms, particularly in sensitive older adults. OBJECTIVES: Our research aimed to systematically assess the relationship between abiotic airborne exposures and changes in body composition among healthy older adults, as well as the potential mediating mechanisms through the serum lipidome. METHODS: From September 2018 to January 2019, we conducted a monthly survey among 76 healthy adults (60–69 years old) in the China Biomarkers of Air Pollutant Exposure (BAPE) study, measuring their personal exposures to 632 abiotic airborne pollutions using MicroPEM and the Fresh Air wristband, 18 body composition indicators from the InBody 770 device, and lipidomics from venous blood samples. We used an exposome-wide association study (ExWAS) and deletion/substitution/addition (DSA) model to unravel complex associations between exposure to contaminant mixtures and body composition, a Bayesian kernel machine regression (BKMR) model to assess the overall effect of key exposures on body composition, and mediation analysis to identify lipid intermediators. RESULTS: The ExWAS and DSA model identified that 2,4,5-T methyl ester (2,4,5-TME), 9,10-Anthracenedione (ATQ), 4b,8-dimethyl-2-isopropylphenanthrene, and 4b,5,6,7,8,8a,9,10-octahydro-(DMIP) were associated with increased body fat mass (BFM), fat mass indicators (FMI), percent body fat (PBF), and visceral fat area (VFA) in healthy older adults [Bonferroni-Hochberg false discovery rate (FDRBH)<0.05]. The BKMR model demonstrated a positive correlation between contaminants (anthracene, ATQ, copaene, di-epi-a-cedrene, and DMIP) with VFA. Mediation analysis revealed that phosphatidylcholine [PC, PC(16:1e/18:1), PC(16:2e/18:0)] and sphingolipid [SM, SM(d18:2/24:1)] mediated a significant portion, ranging from 12.27% to 26.03% (푝-value <0.05), of the observed increase in VFA. DISCUSSION: Based on the evidence from multiple model results, ATQ and DMIP were statistically significantly associated with the increased VFA levels of healthy older adults, potentially regulated through lipid intermediators. These findings may have important implications for identifying potentially harmful environmental chemicals and developing targeted strategies for the control and prevention of chronic diseases in the future, particularly as the global population is rapidly aging. [ABSTRACT FROM AUTHOR]