62 results on '"Pedron, M."'
Search Results
2. Factores predictores de la calidad del sueño en pacientes con migraña crónica
- Author
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Garrigós-Pedrón, M., Segura-Ortí, E., Gracia-Naya, M., and La Touche, R.
- Published
- 2022
- Full Text
- View/download PDF
3. Retrospective cohort study on weight gain among pregnant women of the Italian province of Trento during the 2020 lockdown due to COVID-19
- Author
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Valent, F., primary, Pertile, R., additional, and Pedron, M., additional
- Published
- 2022
- Full Text
- View/download PDF
4. ASSESSMENT OF CANOPY AND GROUND HEIGHT ACCURACY FROM GEDI LIDAR OVER STEEP MOUNTAIN AREAS
- Author
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Kutchartt, E., primary, Pedron, M., additional, and Pirotti, F., additional
- Published
- 2022
- Full Text
- View/download PDF
5. Monitoring viral infections in pregnancy by birth certificate attendance. The experience of province of Trento – Italy
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Piffer, S., primary, Pertile, R., additional, Pedron, M., additional, and Dell’Anna, L., additional
- Published
- 2022
- Full Text
- View/download PDF
6. Structure and high-temperature oxidation behaviour of Cu–Ni–Fe alloys prepared by high-energy ball milling for application as inert anodes in aluminium electrolysis
- Author
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Helle, S., Pedron, M., Assouli, B., Davis, B., Guay, D., and Roué, L.
- Published
- 2010
- Full Text
- View/download PDF
7. Gender and 5-years course of psychosis patients: focus on clinical and social variables
- Author
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Comacchio, C, Lasalvia, A, Bonetto, C, Cristofalo, D, Miglietta, E, Petterlini, S, De Santi, K, Tosato, S, Riolo, R, Cremonese, C, Ceccato, E, Zanatta, G, Ruggeri, M, Tansella, M, Bertani, M, Brambilla, P, Marrella, G, Bissoli, S, Perlini, C, Tito, P, Lunardon, M, Gava, F, Borso, E, Grandina, L, Paliotto, M, Roggia, L, Danieli, A, Poloni, C, Altiero, Mr, Piazza, F, Busana, C, Campi, A, Zanconato, A, Zamorani, P, Binotto, R, Caneva, A, Lazzarin, E, Zordan, G, Dolce, C, Fanchin, Gb, Negro, C, Gardellin, F, Crestale, M, Paiola, L, Sale, A, Morandin, I, Biondi, E, Favaretto, Acg, Geatti, S, Urbani, P, De Rossi, M, Spessotto, J, Penelope, R, Grando, L, Sgnaolin, M, Tozzini, C, Visentin, G, Schiavon, L, Gentile, B, Bolacchi, Mg, Marzotto, L, Moni, F, Rossi, L, Amalric, I, Miceli, C, De Zordo, Mr, Ramon, L, Russo, S, Rossi, R, Casagrande, G, De Nardo, V, Facchetti, A, Ramaciotti, F, Marangon, V, Coppola, G, Marcolin, A, Meneghini, P, Sbraccia, F, Segato, C, Cappellari, L, Cutugno, M, Meneghetti, L, Longhin, L, Paoleschi, B, Scalabrin, D, Antonello, L, Purgato, A, Santucci, G, Tosin, C, Volpato, R, Zurlo, R, Zucchetto, M, Pedron, M, Pinton, S, Benetazzo, M, Pavan, L, Semenzin, M, Sifari, L, Zorzi, F, Martucci, Mm, Magno, N, Meloni, G, Toniolo, E, Pavanati, M, Destro, E, Finotti, L, Fiorio, R, Marsilio, A, Pedrocco, N, Pollola, P, Lazzarotto, L, Nose, F, Rossin, P, Vivenza, V, Mazzoncini, R, Urbani, Andrea, Bianchi, L, Carcereri, G, Lunardi, L, Migliorini, G, Perdona, G, Piazza, C, Lamonaca, D, D'Agostini, G, Boggian, I, Piccione, G, Saladini, E, Gomez, F, Frazzingaro, S, Nicolaou, S, Cordioli, L, Bertolazzi, G, Pagliuca, V, Abate, M, Bortolomasi, M, Giacopuzzi, M, Segala, M, De Nardi, F, Basetto, F, Bernardis, C, Bezzetto, A, and Santi, M
- Subjects
Adult ,Male ,Mental Health Services ,First episode psychosis ,Psychosis ,medicine.medical_specialty ,Time Factors ,Adolescent ,FEP ,Gender ,Insight ,Needs ,Psychopathology ,Unmet needs ,Cohort Studies ,Young Adult ,03 medical and health sciences ,Settore BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA ,Sex Factors ,0302 clinical medicine ,Female patient ,medicine ,Humans ,Psychiatry ,Depressive symptoms ,Demography ,Psychiatric Status Rating Scales ,Health Services Needs and Demand ,business.industry ,Obstetrics and Gynecology ,Middle Aged ,medicine.disease ,030227 psychiatry ,Psychiatry and Mental health ,Insight into illness ,Italy ,Psychotic Disorders ,Male patient ,Female ,business ,Social Adjustment ,030217 neurology & neurosurgery ,Follow-Up Studies - Abstract
Most studies on gender and psychosis have focused on gender differences at illness onset or on the long-term outcome, whereas little is known about the impact of gender on the first years after psychosis onset. A total of 185 first episode psychosis (FEP) patients were followed for 5 years after psychosis onset, and gender differences were explored in psychopathology (PANSS), needs for care (CAN), and insight (SAI-E). Male patients showed more negative symptoms than females over time, whereas female patients showed higher levels of depressive symptoms than males throughout the study period. In addition, female patients presented more functioning unmet needs for care, but higher levels of insight into illness than males. Therapy and rehabilitative programs for FEP patients should be gender-targeted, as gender has proved to impact on psychopathology, needs for care, and insight in the very first years following psychosis onset.
- Published
- 2019
8. Crystal structure of sarcomeric protein FATZ-1 (mini-FATZ-1 construct) in complex with rod domain of alpha-actinin-2
- Author
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Sponga, A., primary, Arolas, J.L., additional, Rodriguez Chamorro, A., additional, Mlynek, G., additional, Hollerl, E., additional, Schreiner, C., additional, Pedron, M., additional, Kostan, J., additional, Ribeiro, E.A., additional, and Djinovic-Carugo, K., additional
- Published
- 2021
- Full Text
- View/download PDF
9. Crystal structure of sarcomeric protein FATZ-1 (d91-FATZ-1 construct) in complex with half dimer of alpha-actinin-2
- Author
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Sponga, A., primary, Arolas, J.L., additional, Rodriguez Chamorro, A., additional, Mlynek, G., additional, Hollerl, E., additional, Schreiner, C., additional, Pedron, M., additional, Kostan, J., additional, Ribeiro, E.A., additional, and Djinovic-Carugo, K., additional
- Published
- 2021
- Full Text
- View/download PDF
10. Prevalence of Huntington's disease in Southern Sardinia, Italy
- Author
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Muroni, A., Murru, M. R., Sechi, M., Ercoli, T., Marrosu, F., Bentivoglio, Anna Rita, Petracca, Martina, Maria Scaglione, C. L., Soliveri, P., Cocco, E., Pedron, M., Murgia, M., Deriu, M., Cuccu, S., Ulgheri, L., Zuccato, C., Defazio, G., Bentivoglio A. R. (ORCID:0000-0002-9663-095X), Petracca M., Muroni, A., Murru, M. R., Sechi, M., Ercoli, T., Marrosu, F., Bentivoglio, Anna Rita, Petracca, Martina, Maria Scaglione, C. L., Soliveri, P., Cocco, E., Pedron, M., Murgia, M., Deriu, M., Cuccu, S., Ulgheri, L., Zuccato, C., Defazio, G., Bentivoglio A. R. (ORCID:0000-0002-9663-095X), and Petracca M.
- Abstract
Background: The frequency of Huntington's disease (HD) may vary considerably, with higher estimates in non Asian populations. In Italy, two recent studies performed in Ferrara county and Molise provided different prevalence estimates, varying from 4.2 × 105 to 10.8 × 105. Here we present a study performed in the Southern part of Sardinia, a large Italian mediterranean island that is considered a genetic isolate. Methods: The study area included the two neighbouring counties of South Sardinia and Cagliari with 353,830 and 431,955 inhabitants respectively on December 31st, 2017 (prevalence date). Case-patients were ascertained through multiple sources in Sardinia and Italy. Results: We identified 54 individuals with HD, of whom 47 were alive on prevalence date. The resulting prevalence rate was 5.98 × 105 in the overall study area, however with marked variations between South Sardinia and Cagliari (9.6 × 105 vs. 3.0 × 105, p = 0.02). In the two study areas, we found similar CAG repeat length in normal alleles (17.5 ± 2.1 vs. 17.7 ± 2.2, p = 0.5). Conclusions: The overall prevalence of HD in Sardinia is close to the correspondent estimates in Europeans. Our findings also highlighted the possibility of local microgeographic variations in the epidemiology of HD.
- Published
- 2020
11. Gender and 5-years course of psychosis patients: focus on clinical and social variables
- Author
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Comacchio, C, Lasalvia, A, Bonetto, C, Cristofalo, D, Miglietta, E, Petterlini, S, De Santi, K, Tosato, S, Riolo, R, Cremonese, C, Ceccato, E, Zanatta, G, Ruggeri, M, Tansella, M, Bertani, M, Brambilla, P, Marrella, G, Bissoli, S, Perlini, C, Tito, P, Lunardon, M, Gava, F, Borso, E, Grandina, L, Paliotto, M, Roggia, L, Danieli, A, Poloni, C, Altiero, Mr, Piazza, F, Busana, C, Campi, A, Zanconato, A, Zamorani, P, Binotto, R, Caneva, A, Lazzarin, E, Zordan, G, Dolce, C, Fanchin, Gb, Negro, C, Gardellin, F, Crestale, M, Paiola, L, Sale, A, Morandin, I, Biondi, E, Favaretto, Acg, Geatti, S, Urbani, P, De Rossi, M, Spessotto, J, Penelope, R, Grando, L, Sgnaolin, M, Tozzini, C, Visentin, G, Schiavon, L, Gentile, B, Bolacchi, Mg, Marzotto, L, Moni, F, Rossi, L, Amalric, I, Miceli, C, De Zordo, Mr, Ramon, L, Russo, S, Rossi, R, Casagrande, G, De Nardo, V, Facchetti, A, Ramaciotti, F, Marangon, V, Coppola, G, Marcolin, A, Meneghini, P, Sbraccia, F, Segato, C, Cappellari, L, Cutugno, M, Meneghetti, L, Longhin, L, Paoleschi, B, Scalabrin, D, Antonello, L, Purgato, A, Santucci, G, Tosin, C, Volpato, R, Zurlo, R, Zucchetto, M, Pedron, M, Pinton, S, Benetazzo, M, Pavan, L, Semenzin, M, Sifari, L, Zorzi, F, Martucci, Mm, Magno, N, Meloni, G, Toniolo, E, Pavanati, M, Destro, E, Finotti, L, Fiorio, R, Marsilio, A, Pedrocco, N, Pollola, P, Lazzarotto, L, Nose, F, Rossin, P, Vivenza, V, Mazzoncini, R, Urbani, Andrea, Bianchi, L, Carcereri, G, Lunardi, L, Migliorini, G, Perdona, G, Piazza, C, Lamonaca, D, D'Agostini, G, Boggian, I, Piccione, G, Saladini, E, Gomez, F, Frazzingaro, S, Nicolaou, S, Cordioli, L, Bertolazzi, G, Pagliuca, V, Abate, M, Bortolomasi, M, Giacopuzzi, M, Segala, M, De Nardi, F, Basetto, F, Bernardis, C, Bezzetto, A, Santi, M, Urbani, A (ORCID:0000-0001-9168-3174), Comacchio, C, Lasalvia, A, Bonetto, C, Cristofalo, D, Miglietta, E, Petterlini, S, De Santi, K, Tosato, S, Riolo, R, Cremonese, C, Ceccato, E, Zanatta, G, Ruggeri, M, Tansella, M, Bertani, M, Brambilla, P, Marrella, G, Bissoli, S, Perlini, C, Tito, P, Lunardon, M, Gava, F, Borso, E, Grandina, L, Paliotto, M, Roggia, L, Danieli, A, Poloni, C, Altiero, Mr, Piazza, F, Busana, C, Campi, A, Zanconato, A, Zamorani, P, Binotto, R, Caneva, A, Lazzarin, E, Zordan, G, Dolce, C, Fanchin, Gb, Negro, C, Gardellin, F, Crestale, M, Paiola, L, Sale, A, Morandin, I, Biondi, E, Favaretto, Acg, Geatti, S, Urbani, P, De Rossi, M, Spessotto, J, Penelope, R, Grando, L, Sgnaolin, M, Tozzini, C, Visentin, G, Schiavon, L, Gentile, B, Bolacchi, Mg, Marzotto, L, Moni, F, Rossi, L, Amalric, I, Miceli, C, De Zordo, Mr, Ramon, L, Russo, S, Rossi, R, Casagrande, G, De Nardo, V, Facchetti, A, Ramaciotti, F, Marangon, V, Coppola, G, Marcolin, A, Meneghini, P, Sbraccia, F, Segato, C, Cappellari, L, Cutugno, M, Meneghetti, L, Longhin, L, Paoleschi, B, Scalabrin, D, Antonello, L, Purgato, A, Santucci, G, Tosin, C, Volpato, R, Zurlo, R, Zucchetto, M, Pedron, M, Pinton, S, Benetazzo, M, Pavan, L, Semenzin, M, Sifari, L, Zorzi, F, Martucci, Mm, Magno, N, Meloni, G, Toniolo, E, Pavanati, M, Destro, E, Finotti, L, Fiorio, R, Marsilio, A, Pedrocco, N, Pollola, P, Lazzarotto, L, Nose, F, Rossin, P, Vivenza, V, Mazzoncini, R, Urbani, Andrea, Bianchi, L, Carcereri, G, Lunardi, L, Migliorini, G, Perdona, G, Piazza, C, Lamonaca, D, D'Agostini, G, Boggian, I, Piccione, G, Saladini, E, Gomez, F, Frazzingaro, S, Nicolaou, S, Cordioli, L, Bertolazzi, G, Pagliuca, V, Abate, M, Bortolomasi, M, Giacopuzzi, M, Segala, M, De Nardi, F, Basetto, F, Bernardis, C, Bezzetto, A, Santi, M, and Urbani, A (ORCID:0000-0001-9168-3174)
- Abstract
Most studies on gender and psychosis have focused on gender differences at illness onset or on the long-term outcome, whereas little is known about the impact of gender on the first years after psychosis onset. A total of 185 first episode psychosis (FEP) patients were followed for 5 years after psychosis onset, and gender differences were explored in psychopathology (PANSS), needs for care (CAN), and insight (SAI-E). Male patients showed more negative symptoms than females over time, whereas female patients showed higher levels of depressive symptoms than males throughout the study period. In addition, female patients presented more functioning unmet needs for care, but higher levels of insight into illness than males. Therapy and rehabilitative programs for FEP patients should be gender-targeted, as gender has proved to impact on psychopathology, needs for care, and insight in the very first years following psychosis onset.
- Published
- 2020
12. The adhesion of tungsten dust on plasma-exposed tungsten surfaces
- Author
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Tolias, Panagiotis, De Angeli, M., Riva, G., Ratynskaia, Svetlana V., Daminelli, G., Laguardia, L., Pedron, M., Ripamonti, D., Uccello, A., Vassallo, E., Tolias, Panagiotis, De Angeli, M., Riva, G., Ratynskaia, Svetlana V., Daminelli, G., Laguardia, L., Pedron, M., Ripamonti, D., Uccello, A., and Vassallo, E.
- Abstract
The adhesion of tungsten dust is measured on plasma-exposed and non-exposed tungsten substrates with the electrostatic detachment method. Tungsten substrates of comparable surface roughness have been exposed to the deuterium plasmas of the GyM linear device and the argon plasmas of rf glow discharges under conditions which invariably modify the surface composition due to physical sputtering. The adhesion has been systematically characterized for different spherical nearly monodisperse dust populations. Independent of the dust size, an approximate 50% post-exposure reduction of the average and spread of the adhesive force has been consistently observed and attributed to surface chemistry modifications., QC 20190326
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- 2019
- Full Text
- View/download PDF
13. Divento bravo a scrivere i miei primi testi
- Author
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Re, Anna Maria, Cazzaniga, S., and Pedron, M.
- Subjects
Scrittura - Published
- 2018
14. The usefulness of emergency room data for integrated surveillance of spontaneous abortion at population level
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Pertile, R., Piffer, S., Pedron, M., Demonti, S., Mereu, L., and Tateo, S.
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Surveillance ,Emergency room ,Miscarriage ,Spontaneous abortion - Published
- 2018
15. Post-abortion check-ups at Trento Family Planning Centre. Characteristics of those users who attended the check-up appointments and trends between 2003 and 2017.
- Author
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Pertile, R., Mazza, R., Pedron, M., Gurgone, P., and Piffer, S.
- Subjects
POST-abortion syndrome ,FAMILY planning ,CERTIFICATION ,DEMOGRAPHIC characteristics ,LOGISTIC regression analysis - Abstract
Copyright of Annali di Igiene, Medicina Preventiva e di Comunità is the property of Societa Editrice Universo s.r.l. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
16. Creatività e alto potenziale: quale rapporto?
- Author
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Bottari, F., Pedron, M., Valenti, C., Antonietti, Alessandro, and Lucangeli
- Subjects
creatività ,Settore M-PSI/01 - PSICOLOGIA GENERALE - Published
- 2017
17. L'enfant gbaya (Afrique française Centrale)
- Author
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Pédron, M.
- Published
- 1927
18. Improving expressive writing in children with Leanring Disabilities: the effects of a training focused on revision
- Author
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Pedron, M, Re, Anna Maria, Mirandola, C, and Cornoldi, C.
- Published
- 2014
19. Dinamiche di trasformazione urbana: l'insula dell'Accademia a Venezia tra ricostruzione storica e percezione visiva
- Author
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Galeazzo, Ludovica and Pedron, M.
- Subjects
Insula dell’Accademia ,iper-rappresentazione ,trasformazioni urbane ,cultura digitale ,percezione - Published
- 2014
20. Microalbuminuria in type 1 diabetes: Rates, risk factors and glycemic threshold
- Author
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Chaturvedi, Nish, Bandinelli, Simona, Mangili, Ruggero, Penno, Guiseppe, Rottiers, Raoul E., Fuller, John H., Karamanos, B., Kofinis, A., Petrou, K., Giorgino, R., Giorgino, F., Picca, G., Angarano, A., De Pergola, G., Ionescu-Tirgoviste, C., Coszma, A., Songini, M., Casu, A., Pedron, M., Fossarello, M., Ferriss, J. B., Grealy, G., Keefe, D. O., White, A., Cleary, P. E., Toeller, M., Arden, C., Rottiers, R., Tuyttens, C., Priem, H., Ebeling, P., Kylliainen, M., Kyostio-Renvall, T., Idzior-Walus, B., Sieradzki, J., Cyganek, K., Lemkes, H. H. P. J., Roest, C., Nunes-Correa, J., Rogado, M. C., Gardete-Correia, L., Cardoso, M. C., Michel, G., Wirion, R., Cardillo, S., Pozza, G., Mangili, R., Asnaghi, V., Lattanzio, Rosangela, Galardi, G., Standl, E., Schaffler, B., Brand, H., Harms, A., Ben Soussan, D., Verier-Mine, O., Fuller, J. H., Holloway, J., Asbury, L., Betteridge, D. J., Cathelineau, G., Bouallouche, A., Villatte Cathelineau, B., Santeusanio, F., Rosi, G., Dâ Alessandro, V., Cagini, C., Navalesi, R., Penno, G., Bandinelli, S., Miccoli, R., Ghirlanda, G., Saponara, C., Cotroneo, P., Manto, A., Minnella, A., Ward, J. D., Tesfaye, S., Eaton, S., Mody, C., Porta, M., Perin, P. Cavallo, Borra, M., Giunti, S., Papazoglou, N., Manes, Gianfranco, Muggeo, M., Iagulli, M., Irsigler, K., Abrahamian, H., Walford, S., Wardle, E. V., Sinclair, J., Hughes, S., Roglic, G., Metelko, Z., Resman, Z., Sjolie, A. -. K., Chaturvedi, N., Ferriss, B., Webb, D., Viberti, G. -. C., Swaminathan, R., Lumb, P., Collins, A., Sankaralingham, S., Aldington, S., Mortemore, T., and Lipinski, H.
- Subjects
Albuminuria ,Blood sugar control ,Cardiovascular disease ,Insulin resistance ,Renal disease ,Adolescent ,Adult ,Blood Glucose ,Body Constitution ,Cohort Studies ,Diabetes Mellitus, Type 1 ,Differential Threshold ,Disease Progression ,Europe ,Female ,Follow-Up Studies ,Humans ,Incidence ,Insulin Resistance ,Male ,Middle Aged ,Prospective Studies ,Reference Values ,Risk Factors ,Triglycerides ,Nephrology ,endocrine system diseases ,urologic and male genital diseases ,Gastroenterology ,Waist–hip ratio ,Proteinuria ,Settore MED/30 - MALATTIE APPARATO VISIVO ,female genital diseases and pregnancy complications ,medicine.symptom ,Type 1 ,medicine.medical_specialty ,Internal medicine ,Diabetes mellitus ,Diabetes Mellitus ,medicine ,Risk factor ,Glycemic ,Type 1 diabetes ,business.industry ,nutritional and metabolic diseases ,medicine.disease ,Endocrinology ,Microalbuminuria ,business - Abstract
Microalbuminuria in type 1 diabetes: Rates, risk factors and glycemic threshold.BackgroundThe occurrence of microalbuminuria in type 1 diabetes is strongly predictive of renal and cardiovascular disease and is still likely to occur despite improvements in glycemic control. A better understanding of microalbuminuria is required to inform new interventions. We determined the incidence and risk factors for microalbuminuria [albumin excretion rate (AER) 20 to 200 μg/min] in the EURODIAB Prospective Complications Study.MethodsThis is a seven-year follow-up (between 1988 and 1991) of 1134 normoalbuminuric men and women (aged 15 to 60) with type 1 diabetes from 31 European centers. Risk factors and AER were measured centrally.ResultsThe incidence of microalbuminuria was 12.6% over 7.3 years. Independent baseline risk factors were HbA1c (7.1 vs. 6.2%, P = 0.0001) and AER (9.6 vs. 7.8 μg/min, P = 0.0001) and, independent of these, fasting triglyceride (0.99 vs. 0.88 mmol/L, P = 0.01), low-density lipoprotein cholesterol (3.5 vs. 3.2 mmol/L, P = 0.02), body mass index (24.0 vs. 23.4 kg/m2, P = 0.01), and waist to hip ratio (WHR; 0.85 vs. 0.83, P = 0.009). Triglyceride and WHR risk factors were nearly as strong as AER in predicting microalbuminuria (standardized regression effects of 1.3 for triglyceride and WHR and 1.5 for AER). Blood pressure at follow-up, but not at baseline, was also raised in those who progressed. There was no evidence of a threshold of HbA1c on microalbuminuria risk.ConclusionsThe incidence of microalbuminuria in patients with type 1 diabetes remains high, and there is no apparent glycemic threshold for it. Markers of insulin resistance, such as triglyceride and WHR, are strong risk factors. Systemic blood pressure is not raised prior to the onset of microalbuminuria.
- Published
- 2001
21. Visualizing Venice, Mappare e modellare la storia urbana: il caso dell’insula dell’Accademia
- Author
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Galeazzo, Ludovica and Pedron, M.
- Published
- 2013
22. A Virtual Garden: The Scenographic Jappelli’s engravings for Palazzo della Ragione in Padua
- Author
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Friso, I., Giordano, A, Monteleone, C., and Pedron, M.
- Published
- 2013
23. Control Strategies for Hybrid Vehicles in Mountainous Areas
- Author
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Brouk, S., primary, Buey, M., additional, Ly, S., additional, Pedron, M., additional, and Burgalat, S., additional
- Published
- 2015
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- View/download PDF
24. Trends in Lung Cancer and Smoking Behavior in Italy: An Alarm Bell for Women
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Trama, Annalisa, Boffi, Roberto, Contiero, Paolo, Buzzoni, Carlotta, Pacifici, Roberta, Mangone, Lucia, Coviello, V, Buzzoni, C, Fusco, M, Barchielli, A, Cuccaro, F, De Angelis, R, Giacomin, A, Luminari, S, Randi, G, Mangone, L, Mazzoleni, G, Bulatko, A, Devigili, E, Tschugguel, B, De Valiere, E, Facchinelli, G, Falk, M, Vittadello, F, Coviello, V, Cuccaro, F, Calabrese, A, Pinto, A, Cannone, G, Vitali, ME, Galasso, R, Del Riccio, L, Napolitano, D, Sampietro, G, Ghisleni, S, Giavazzi, L, Zanchi, A, Zucchi, A, Giacomin, A, Vercellino, PC, Andreone, S, Fedele, M, Barale, A, Germinetti, F, Magoni, M, Salvi, O, Puleio, M, Gerevini, C, Chiesa, R, Lonati, F, Cavalieri d'Oro, L, Rognoni, M, Le Rose, L, Merlo, E, Bracchi, A, Negrino, L, Pezzuto, L, Ardizzone, A, Spagnolo, G, Cozzi, E, De Lorenzism, L, Lotti, F, Pagliara, MC, D'Argenzio, A, D'Abronzo, M, De Francesco, D, Pereira da Silva, MCM, Menditto, V, Perrotta, E, Pesce, MT, Sessa, A, Sciacca, S, Sciacchitano, S, Fidelbo, M, Benedetto, G, Benedetto, A, Calabretta, LMR, Caruso, AM, Castaing, M, Di Prima, AA, Dinaro, YM, Fidelbo, P, Grosso, G, Ippolito, A, Irato, E, Leone, A, Paderni, F, Pesce, PNR, Pollina Addario, S, Savasta, A, Sciacchitano, CG, Torrisi, AAM, Torrisi, A, Varvarà, M, Viscosi, C, Sutera Sardo, A, Sia, A, Scalzi, S, Lavecchia, AM, Mancuso, P, Nocera, V, Mancusi, F, Del Duca, S, Gola, G, Corti, M, Caparelli, M, Ferretti, S, Marzola, L, Migliari, E, Carletti, N, Biavati, P, Petrucci, C, Serraino, D, Angelin, T, Bidoli, E, Birri, S, Dal Maso, L, De Dottori, M, De Santis, E, Forgiarini, O, Zucchetto, A, Zanier, L, Pannozzo, F, Busco, S, Rossi, M, Curatella, S, Bugliarello, E, Macci, L, Bernazza, E, Calabretta, F, Tamburrino, S, Sperduti, I, Tamburo, L, Serafini, G, Quarta, F, Melcarne, A, Golizia, MG, Arciprete, C, De Maria, V, Filiberti, RA, Casella, C, Marani, E, Puppo, A, Celesia, MV, Cogno, R, Vitarelli, S, Ricci, P, Autelitano, M, Ghilardi, S, Leone, R, Filipazzi, L, Bonini, A, Giubelli, C, Russo, AG, Quattrocchi, M, Distefano, R, Panciroli, E, Bellini, A, Pinon, M, Spinosa, S, Spagnoli, G, Carrozzi, G, Cirilli, C, Valla, K, Amendola, V, Fusco, M, Bellatalla, C, Ciullo, V, Di Buono, M, Fusco, M, Panico, M, Perrotta, C, Vitale, MF, Usala, M, Pala, F, Sini, GM, Pintori, N, Canu, L, Demurtas, G, Doa, N, Vitale, F, Cusimano, R, Traina, A, Guttadauro, A, Cascio, MA, Mannino, R, Ravazzolo, B, Brucculeri, MA, Rudisi, G, Adamo, MS, Amodio, R, Costa, A, Zarcone, M, Sunseri, R, Bucalo, G, Trapani, C, Staiti, R, Michiara, M, Bozzani, F, Sgargi, P, Boschetti, L, Migliazza, S, Reggiani, E, Incardona, N, Borciani, E, Seghini, P, Prazzoli, R, Zanetti, R, Rosso, S, Patriarca, S, Prandi, R, Sobrato, I, Gilardi, F, Busso, P, Sacchetto, L, Tumino, R, Cascone, G, Frasca, G, Giurdanella, MC, Martorana, C, Morana, G, Nicita, C, Rollo, PC, Ruggeri, MG, Spata, E, Vacirca, S, Mangone, L, Vicentini, M, Di Felice, E, Pezzarossi, A, Ferrari, F, Roncaglia, F, Sacchettini, C, Caroli, S, Falcini, F, Colamartini, A, Bucchi, L, Balducci, C, Ravegnani, M, Vitali, B, Cordaro, C, Caprara, L, Giuliani, O, Giorgetti, S, Palumbo, M, Vattiato, R, Ravaioli, A, Mancini, S, Caiazzo, AL, Cavallo, R, Colavolpe, AFG, D'Alessandro, A, Iannelli, A, Lombardo, C, Senatore, G, Sensi, F, Cesaraccio, R, Pirino, D, Mura, F, Contrino, ML, Madeddu, A, Tisano, F, Dinaro, Y, Muni, A, Mizzi, M, Bella, F, Rossitto, L, Sacco, G, Aletta, P, Colanino Ziino, A, Maspero, S, Fanetti, AC, Cometti, I, Cecconami, L, Minerba, S, Mincuzzi, A, Carone, S, Tanzarella, M, Galluzzo, C, Barchielli, A, Buzzoni, C, Caldarella, A, Corbinelli, A, Intrieri, T, Di Dia, PP, Manneschi, G, Nemcova, L, Visioli, C, Zappa, M, Candela, G, Scuderi, T, Crapanzano, G, Taranto, V, Piffer, S, Gentilini, M, Rizzello, R, Bombarda, L, Pedron, M, Clivati, E, Stracci, F, D'Alò, D, Scheibel, M, Costarelli, D, Spano, F, Rossini, S, Santucci, C, Petrinelli, AM, Solimene, C, Bianconi, F, Brunori, V, Tagliabue, G, Contiero, P, Tittarelli, A, Fabiano, S, Maghini, A, Codazzi, T, Barigelletti, G, D'Agostino, A, Modonesi, C, Rugge, M, Baracco, M, Baracco, S, Bovo, E, Dal Cin, A, Fiore, AR, Greco, A, Guzzinati, S, Martin, G, Memo, L, Monetti, D, Rizzato, S, Rosano, A, Stocco, C, Tognazzo, S, Zorzi, M, Brustolin, A, Beggiato, S, Aniceti, S, Fiocchetti, L, Schirra, G, Galeotti, P, Capati, A, Nami, A, Montanaro, M, Verrico, G, Poleggi, F, Rashid, I, Grappasonni, I, Pascucci, C, Merletti, F, Magnani, C, Pastore, G, Terracini, B, Alessi, D, Cena, T, Lazzarato, F, Macerata, V, Maule, M, Mosso, ML, Sacerdote, C, Romanelli, A, Mangone, L, Storchi, C, Sala, O, Gabbi, C, Gennaro, V, Benfatto, L, Malacarne, D, Lando, C, Campi, MG, Mazzucco, G, Ponz de Leon, M, Domati, F, Rossi, G, Goldoni, CA, Kaleci, S, Rossi, F, Benatti, P, Roncucci, L, Di Gregorio, C, Magnani, G, Pedroni, M, Maffei, S, Mariani, F, Reggiani-Bonetti, L, Sassatelli, R, Cassetti, T, Giorgi Rossi, P, and Vicentini, M
- Abstract
Introduction The epidemiology of lung cancer is changing worldwide, with smoking being the key driver of lung cancer incidence and mortality. Our aim is to analyze the incidence, survival and mortality trends in Italy in the framework of the 2017 survey on smoking behavior in Italy.Methods AIRTUM 2017 reports on cancer survival and incidence; 2017 survey on smoking behavior in Italy.Results Men achieved progress in lung cancer control characterized by a decrease in incidence and mortality and an increase in survival. The decreasing use of tobacco in men (from 60% in the 1960s to 24% in 2017) was most likely responsible for the decreasing incidence and mortality. Women showed no progress: although survival improved slightly, the incidence and mortality were both on the rise. This was most likely due to the increasing smoking rates in women in the 1970s and 80s. Of major concern is the accelerated rise in the number of smoking women from 4.6 million in 2016 to 5.7 million in 2017 compared to the decrease observed in men (from 6.9 to 6 million).Conclusions The incidence and mortality trends in males clearly demonstrate that primary prevention is the most effective way to reduce lung cancer mortality. By contrast, a 24% increase in the prevalence of smoking among women in just 1 year is extremely worrying for the future, and calls for immediate action by targeted strategies to reduce tobacco consumption in women and avert the dreadful prospect of a lung cancer epidemic in Italy.
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- 2017
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25. Diffusion of blackfly species(Diptera: Simulidae) in Friuli Venezia Giulia (Italy)
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Ghetti, Pier Francesco, Tagliapietra, Davide, Losso, Chiara, VOLPI GHIRARDINI, Annamaria, Ghirelli, L, Pedron, M, and Rivosecchi, L.
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- 2000
26. Analisi delle cause e proposte per limitare gli effetti dello sviluppo anomalo di insetti simulidi nell'area di Pocenia, Rivignano e Teor
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Ghetti, Pier Francesco, Sburlino, Giovanni, Sfriso, Adriano, VOLPI GHIRARDINI, Annamaria, Ghirelli, L, Tagliapietra, Davide, Rivosecchi, L, Losso, Chiara, and Pedron, M.
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- 1999
27. Epidemiological pattern of Schönlein-Henoch vasculitis
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Facchin, Paola, Vianello, A., Gervasi, S., Murer, L., Drei, F., Pedron, M. E., Mengarda, G., and Zacchello, G.
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- 1994
28. Caratteristiche epidemiologiche della Porpora di Schönlein-Henoch
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Gervasi, S., Facchin, Paola, Vianello, A., Murer, L., Drei, F., Pedron, M. E., Mengarda, G., and Zacchello, G.
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- 1993
29. Expressive writing difficulties in children described as exhibiting ADHD symptoms.
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Re AM, Pedron M, and Cornoldi C
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Three groups of children of different ages who were considered by their teachers as showing symptoms of attention-deficit/hyperactivity disorder (ADHD) and matched controls were tested in a series of expressive writing tasks, derived from a standardized writing test. In the first study, 24 sixth- and seventh-grade children with ADHD symptoms wrote a description of an image. The ADHD group's expressive writing was worse than that of the control group and associated with a higher number of errors, mainly concerning accents and geminates. The second study showed the generality of the effect by testing younger groups of children with ADHD symptoms and controls with another description task where a verbal description was substituted for the picture stimulus. The third study extended the previous observations with another type of writing task, the request of writing a narrative text. In all the three studies, children with ADHD symptoms scored lower than controls on four qualitative parameters (adequacy, structure, grammar, and lexicon), produced shorter texts, and made more errors. These studies show that children with ADHD symptoms have school difficulties also in writing--both in spelling and expression--and that these difficulties are extended to different tasks and ages. [ABSTRACT FROM AUTHOR]
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- 2007
30. [Antenatal course attendance among primiparous mothers, with physiological pregnancy and birth at term in Trentino (Northern Italy): characteristics of non-attender women and benefits among attender women in pregnancy behaviours, type of birth delivery and neonatal outcomes]
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Riccardo Pertile, Pedron, M., Berlanda, M., and Piffer, S.
31. Adherence to the screening program for HBV infection in pregnant women and application of the immunoprophylaxis protocol in babies born to HBV carrier women | Adesione al programma di screening per Virus dell'epatite B nelle donne gravide ed applicazione del protocollo di immunoprofilassi nel neonato
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Masia, G., Luigi Minerba, Aresu, C., Brundu, A., Campanelli, C., Pedron, M., Rossi, G., Tirotto, M. T., and Coppola, R. C.
32. Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study
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Peeters, Stijn A., Engelen, Lian, Buijs, Jacqueline, Chaturvedi, Nish, Fuller, John H., Schalkwijk, Casper G., Stehouwer, Coen D, Karamanos, B., Kofinis, A., Petrou, K., Giorgino, F., Picca, G., Angarano, A., Null, de P. e. r. g. o. l. a. G., Laviola, L., Giorgino, R., Ionescu Tirgoviste, C., Coszma, A., Guja, C., Songini, M., Casu, A., Pedron, M., Pintus, S., Fossarello, M., Ferriss, J. B., Grealy, G., O'Keefe, D., Toeller, M., Arden, C., Rottiers, R., Tuyttens, C., Priem, H., Ebeling, P., Kylliainen, M., Koivisto, V. A., Idzior Walus, B., Sieradzki, J., Cyganek, K., Solnica, B., Lemkes, H. H. P. J., Lemkes Stuffken, J. C., Nunes Correa, J., Rogado, M. C., Gardete Correia, L., Cardoso, M. C., Silva, A., Boavida, J., Machado Sa Marques, M., Michel, G., Wirion, R., Cardillo, S., Pozza, G., Mangili, R., Asnaghi, V., Standl, E., Schaffler, B., Brand, H., Harms, A., Ben Soussan, M., Verier Mine, O., Fallas, P., Fallas, M. C., Fuller, J. H., Holloway, J., Asbury, L., Betteridge, D. J., Cathelineau, G., Bouallouche, A., Villatte Cathelineau, B., Santeusanio, F., Rosi, G., D'Alessandro, V., Cagini, C., Bottini, P., Reboldi, G. P., Navalesi, R., Penno, Giuseppe, Bandinelli, S., Miccoli, Roberto, Nannipieri, Monica, Ghirlanda, G., Saponara, C., Cotroneo, P., Manto, A., Minnella, A., Ward, J. D., Tesfaye, S., Eaton, S., Mody, C., Borra, M., Cavallo Perin, P., Giunti, S., Grassi, G., Pagano, G. F., Porta, M., Sivieri, R., Vitelli, F., Veglio, M., Papazoglou, N., Manes, G., Muggeo, M., Iagulli, M., Cacciatori, V., Cattedra di Malattie del Metabolismo, V., Irsigler, K., Abrahamian, H., Walford, S., Sinclair, J., Hughes, S., Mclelland, V., Ward, J., Roglic, G., Metelko, Z., Pepeonik, Z. R., Clinicum, Department of Medicine, Interne Geneeskunde, MUMC+: MA Interne Geneeskunde (3), and RS: CARIM - R3 - Vascular biology
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Male ,Endocrinology, Diabetes and Metabolism ,Matrix metalloproteinase ,Gastroenterology ,Cohort Studies ,Endocrinology ,Prospective Studies ,Endothelial dysfunction ,Original Investigation ,Settore MED/30 - MALATTIE APPARATO VISIVO ,Middle Aged ,Cardiovascular disease ,3. Good health ,Europe ,Diabetes and Metabolism ,Albuminuria ,Retinopathy ,Tissue inhibitor of metalloproteinase ,Type 1 diabetes ,Adult ,Biomarkers ,Cross-Sectional Studies ,Diabetes Complications ,Diabetes Mellitus, Type 1 ,Female ,Humans ,Matrix Metalloproteinase 10 ,Matrix Metalloproteinase 2 ,Matrix Metalloproteinase 3 ,Tissue Inhibitor of Metalloproteinase-1 ,Vascular Diseases ,Cardiology and Cardiovascular Medicine ,medicine.symptom ,Type 1 ,medicine.medical_specialty ,education ,Inflammation ,Diabetes mellitus ,Internal medicine ,medicine ,Diabetes Mellitus ,business.industry ,Settore MED/09 - MEDICINA INTERNA ,medicine.disease ,3121 General medicine, internal medicine and other clinical medicine ,business - Abstract
Background Impaired regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to vascular complications in patients with type 1 diabetes. We investigated associations between plasma MMP-1, −2, −3, −9, −10 and TIMP-1, and cardiovascular disease (CVD) or microvascular complications in type 1 diabetic patients. We also evaluated to which extent these associations could be explained by low-grade inflammation (LGI) or endothelial dysfunction (ED). Methods 493 type 1 diabetes patients (39.5 ± 9.9 years old, 51% men) from the EURODIAB Prospective Complications Study were included. Linear regression analysis was applied to investigate differences in plasma levels of MMP-1, −2, −3, −9, −10, and TIMP-1 between patients with and without CVD, albuminuria or retinopathy. All analyses were adjusted for age, sex, duration of diabetes, Hba1c and additionally for other cardiovascular risk factors including LGI and ED. Results Patients with CVD (n = 118) showed significantly higher levels of TIMP-1 [β = 0.32 SD (95%CI: 0.12; 0.52)], but not of MMPs, than patients without CVD (n = 375). Higher plasma levels of MMP-2, MMP-3, MMP-10 and TIMP-1 were associated with higher levels of albuminuria (p-trends were 0.028, 0.004, 0.005 and 0.001, respectively). Severity of retinopathy was significantly associated with higher levels of MMP-2 (p-trend = 0.017). These associations remained significant after further adjustment for markers of LGI and ED. Conclusions These data support the hypothesis that impaired regulation of matrix remodeling by actions of MMP-2, -3 and-10 and TIMP-1 contributes to the pathogenesis of vascular complications in type 1 diabetes. Electronic supplementary material The online version of this article (doi:10.1186/s12933-015-0195-2) contains supplementary material, which is available to authorized users.
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33. Jagemann segreto. Incontri e sorprese sull vie delle idee fra Italia e Germania
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CANTARUTTI, GIULIA, S. Brunetti, J. Klingebeil-Schieke, C.M. Pedron, M.-C. Piotrowski, A. Ruggieri, R. Schreiber, and Cantarutti, Giulia
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Magliabechi ,Rinnovamento scientifico-rinnovamento religioso ,Transfert culturale italo-tedesco ,Galilei ,bibliotecario/acquisti librari ,"Gazzetta di Weimar" ,Bodoni ,Büsching - Abstract
Christian Joseph Jagemann (1735-1804) è noto agli studiosi di estetica per il saggio sul buon gusto nelle belle arti scoperto nel 1910 da Benedetto Croce e ai linguisti per il fortunatissimo Dizionario italiano-tedesco e tedesco-italiano uscito per la prima volta nel 1790. Nel presente contributo viene studiato come esempio del ruolo degli incontri in biblioteca e del transfert materiale di libri, sfruttando materiale inedito a partire dalle lettere indirizzategli da Carlo Denina oggi conservate nel Goethe-und-Schiller-Archiv di Weimar. L’acquisto del De tribus impostoribus compiuto da Jagemann nel periodo in cui era bibliotecario a Weimar viene esaminato nel suo retroterra, così pure il suo interesse per Galileo, da cui nasce la Geschichte des Lebens und Schriften des Galileo Galilei (1784-1785). Lo studio del fondo Amaduzzi della Rubiconia Accademia dei Filopatridi di Savignano sul Rubicone mostra a quali ambienti e a quali istanze di rinnovamento scientifico e di rinnovamento religioso fosse legato Jagemann durante il periodo trascorso fra Firenze e Roma, quando grazie a Giovanni Lami diventa membro dell’Accademia fiorentina dei Georgofili. Vengono studiati in particolare il manoscritto del 1762 (Cod 303 della Biblioteca Angelica), le traduzioni tratte dal “Giornale de’ letterati di Pisa” e la traduzione della Neue Erdbeschreibung di Büsching. Risultato della ricerca è quello di avere ricostruito il percorso sotteso alla “Gazzetta di Weimar” (apparsa fra il 1787 e il 1789, ristampata anastaticamente senza alcun commento nel 1999) e di avere più in generale recuperato l’effettiva ricchezza e complessità della mediazione culturale di questo tedesco nato cattolico e morto protestante, da riconoscersi come figura cruciale nel transfert culturale italo-tedesco.
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- 2016
34. Prevalence of gestational diabetes and recourse to postpartum oral glucose tolerance test in the Autonomous Province of Trento (Italy).
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Piffer S, Pedron M, Rizzello R, Orrasch M, Zambotti F, and Zardini S
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- Female, Pregnancy, Humans, Glucose Tolerance Test, Prevalence, Postpartum Period, Insulin therapeutic use, Blood Glucose analysis, Diabetes, Gestational diagnosis, Diabetes, Gestational epidemiology, Diabetes, Gestational drug therapy
- Abstract
Objective: The occurrence of gestational diabetes (GDM) is increasing worldwide, and such a diagnosis is important for women's health beyond pregnancy. Therefore, many guidelines suggest the re-evaluation of glucose tolerance with a postpartum oral glucose tolerance test (OGTT) in women with GDM. This study reports the prevalence of GDM and the use of a postpartum OGTT in women assisted at maternity units in the Autonomous Province of Trento in the years 2017-2018, investigating the socio-demographic and health-care variables that can facilitate access to the test., Study Design: For the diagnosis of GDM, the International Association of Diabetes and Pregnancy Study Group criteria were used. The Birth Assistance Certificate and the Hospital Information System were used to retrieve clinical and socio-demographic data. Univariate and multivariate analyses were performed to evaluate the stratification of the use of a postpartum OGTT., Results: In total, 8,308 pregnant women were assisted at the maternity units in Trento. There were 532 recorded cases of GDM (266 cases per year) and the overall average prevalence was 6.4 % (95 % CI, 5.90-6.90), 4.9 % of whom were Italian (95 % CI, 4.38-5.42) and 10.4 %, foreigners (95 % CI, 9.13-11.67). 135 women diagnosed with GDM and residing in Trento out of 513 were evaluated using a postpartum OGTT (26.3%, CI 95% 22.50-30.10), with pathological results in 61 cases (45.2%). In the multivariate analyses, insulin therapy during pregnancy, delivery at a third-level birth point, and a discharge letter informing of the presence of GDM and of the need for a postpartum OGTT were independent factors associated with the probability of carrying out a postpartum OGTT., Conclusions: The prevalence of GDM in our study is lower than in previous Italian studies; however, it is consistent with European data. The proportion of women who were assessed using the postpartum OGTT is lower than that reported by previous studies. The health-care factors seem predominant among the socio-demographic characteristics of the cases in influencing access to the test. The awareness of women, the sharing of guidelines among the different sectors of the health system, and an optimal management of the discharge from the birth point are critical in ensuring an optimal follow-up in women with GDM., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier B.V. All rights reserved.)
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- 2023
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35. Screening of group B Streptococcus infection in pregnancy and neonatal outcomes in the province of Trento, Italy.
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Piffer S, Rizzello R, Pedron M, Dellanna L, and Lauriola AL
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The study analyzes the trend of group B streptococcal (GBS) infection in pregnancy in the province of Trento, Italy, where a universal screening of GBS infection in pregnancy has been active for some time. Data from pregnant women who gave birth at local maternity units between 2015-2019 were obtained from birth attendance certificates (BAC), the main - and mandatory - source of information for monitoring pregnancies, births and neonatal health in Italy. The BAC used in the province of Trento acquires the results of a vast range of infections in pregnancy. The data collected from the BAC were integrated with those provided by the Hospital Information System (SIO). The occurrence of neonatal GBS infection was investigated on 2019 birth cohort, using the hospital discharge archive as an ancillary information source. Between 2015-2019, 20,905 pregnant women received care at maternity units of the province of Trento, Italy, of whom 25.5% were foreigners. The average coverage of GBS testing in pregnancy was 91.8% (95% CI 91.25-92.35) without significant variations from one year to the next. Test coverage varies in relation to maternity units and some socio-demographic characteristics of mothers. The average proportion of GBS positive cases over the study period was 21.0% (95% CI 20.7-21.3), a value that does not show statistically significant changes from one year to the next. The proportion of positive cases appears uneven among the subgroups of pregnant women considered, even if the differences are not statistically significant. In the 2019 birth cohort, newborns to GBS-positive mothers had an excess of stillbirths, of those born with Apgar at 5 minutes <7 and hospitalized at birth. However, these excesses were not statistically significant. Intravenous Antibiotic Prophylaxis (IAP) was performed in 86.8% of births from GBS positive mothers who had an indication for IAP. IAP was inadequate in 7.4% of the GBS positive mothers. Postnatal evaluation of 783 live births to GBS positive mothers identified 3 cases of early neonatal GBS infection. The incidence of neonatal GBS infection over the whole series of live births is 0.71/1,000 (95% CI 0.56-0.86), 0.68/1000 (CI 95% 0.55-0.79) in Italians and 1.07/1000 (95% CI 0.45-1.65) in foreigners. Data collection on infections in pregnancy through BAC allows area-based assessment. The quality of the data recorded in the BAC can be considered satisfactory but it was necessary to access to other information sources. The local availability of various information sources should allow periodic audits and closer monitoring of neonatal GBS infection., Competing Interests: Conflicts of interest None, (Copyright © 2016 - 2022 InfezMed.)
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- 2022
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36. Absence of Intermediates in the BINOL-Derived Mg(II)/Phosphate-Catalyzed Desymmetrizative Ring Expansion of 1-Vinylcyclobutanols.
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Capel E, Rodríguez-Rodríguez M, Uria U, Pedron M, Tejero T, Vicario JL, and Merino P
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The catalyzed desymmetrizative ring expansion of alkenylcyclobutanols promoted by halofunctionalization of the alkene moiety with N -bromosuccinimide has been experimentally and computationally studied. The reaction yields highly enantioenriched cyclopentanones bearing two all-carbon quaternary stereocenters, one of them being generated in the rearrangement of the cyclobutane ring and the other by enantioselective desymmetrization. The reaction is competitive with the formation of a spiroepoxide, but it turns completely selective toward the cyclopentanone when a chiral bisphosphonium magnesium salt is employed as a catalyst. Mechanistic studies support the formation of an ion pair leading to a complex with only a unit of phosphoric acid, which is the resting state of the catalytic cycle. Calculations reproduce in an excellent way the observed reactivity and predict the effect exerted by the substituents of the aromatic ring linked to the double bond. The computational studies also revealed the reaction as a highly asynchronous concerted process taking place as one kinetic step but in two stages: (i) halogenation of the double bond and (ii) rearrangement of the cyclobutane. No intermediates are present in the reaction as energy minima. The experimental scope of the reaction further confirms the predictions for the observed reactivity and selectivity.
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- 2022
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37. Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin.
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Sponga A, Arolas JL, Schwarz TC, Jeffries CM, Rodriguez Chamorro A, Kostan J, Ghisleni A, Drepper F, Polyansky A, De Almeida Ribeiro E, Pedron M, Zawadzka-Kazimierczuk A, Mlynek G, Peterbauer T, Doto P, Schreiner C, Hollerl E, Mateos B, Geist L, Faulkner G, Kozminski W, Svergun DI, Warscheid B, Zagrovic B, Gautel M, Konrat R, and Djinović-Carugo K
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In sarcomeres, α-actinin cross-links actin filaments and anchors them to the Z-disk. FATZ (filamin-, α-actinin-, and telethonin-binding protein of the Z-disk) proteins interact with α-actinin and other core Z-disk proteins, contributing to myofibril assembly and maintenance. Here, we report the first structure and its cellular validation of α-actinin-2 in complex with a Z-disk partner, FATZ-1, which is best described as a conformational ensemble. We show that FATZ-1 forms a tight fuzzy complex with α-actinin-2 and propose an interaction mechanism via main molecular recognition elements and secondary binding sites. The obtained integrative model reveals a polar architecture of the complex which, in combination with FATZ-1 multivalent scaffold function, might organize interaction partners and stabilize α-actinin-2 preferential orientation in Z-disk. Last, we uncover FATZ-1 ability to phase-separate and form biomolecular condensates with α-actinin-2, raising the question whether FATZ proteins can create an interaction hub for Z-disk proteins through membraneless compartmentalization during myofibrillogenesis., (Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).)
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- 2021
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38. Esiti avversi perinatali correlati all'indice di massa corporea pregravidico.
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Pertile R, Poggianella S, Pedron M, and Piffer S
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- Female, Humans, Infant, Newborn, Italy epidemiology, Pregnancy, Retrospective Studies, Obesity, Maternal epidemiology, Pregnancy Outcome epidemiology
- Abstract
Background: a high body mass index (BMI) during pregnancy has been associated with an increased risk of complications and adverse outcomes for both mother and infant., Objectives: to analyse the main adverse maternal and neonatal outcomes associated with maternal excess weight and obesity., Design: retrospective epidemiological study., Setting and Participants: data extrapolated from the Birth Attendance Certificate information flow of the Autonomous Province of Trento (Northern Italy) between 2015 and 2019. A total of 20,756 women with data regarding maternal height and weight at the start of pregnancy were included in the analysis., Main Outcome Measures: gestational outcome variables studied were gestational diabetes, hypertensive disorders, premature birth, and still births. Outcomes considered during labour and delivery were type of delivery, induction, episiotomy and post-partum haemorrhage. Neonatal outcomes were birth weight, Apgar score, need for resuscitation, and hospitalisation in the neonatal intensive care unit (NICU). Lastly, exclusive breastfeeding at discharge was analysed., Results: considering the population of pregnant women, 68.3% of women were classified as normal-weight, 9.5% as underweight, 16.0% as overweight, and 6.3% as obese. Maternal excess weight and obesity were seen to be associated with an increased risk of gestational diabetes, gestational hypertension, preeclampsia, caesarean section, induction, post-partum bleeding, foetal macrosomia, and the need for neonatal resuscitation and hospitalisation in the NICU. Infants born to overweight and obese mothers were also less likely to be breastfed., Conclusions: excess weight and obesity are important risk factors for health and contribute to the onset of complications during pregnancy and adverse perinatal and long-term outcomes. Programming and implementing public health promotion schemes aimed at preventing excessive weight gain in the reproductive age could significantly improve maternal and foetal health.
- Published
- 2021
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39. Post-abortion check-ups at Trento Family Planning Centre. Characteristics of those users who attended the check-up appointments and trends between 2003 and 2017.
- Author
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Pertile R, Mazza R, Pedron M, Gurgone P, and Piffer S
- Subjects
- Ambulatory Care Facilities, Case-Control Studies, Family Planning Services, Female, Humans, Pregnancy, Retrospective Studies, Abortion, Induced
- Abstract
Background: The purpose of the study was to analyse the trend for post-abortion check-ups among users requesting the abortion certification from Trento Family Planning Center between 2003 and 2017., Study Design: Retrospective case-control study., Methods: During the study period, the Trento Family Planning Center issued a total of 3,870 abortion certificates (46% regarding foreign nationals). The social and demographic characteristics of those users who attended the post-abortion check-up appointments, and of those who did not, were compared., Results: The proportion of resident users who returned for a post-abortion check-up increases significantly during the study period. The multiple logistic regression analysis model indicates that the factors associated with the likelihood of a return for a post-abortion check-up are: possession of medium to high academic qualifications (> 8 years) versus low qualifications, being a non-EU or Asian citizen, being a minor and being nulliparous or multiparous versus primiparous., Conclusions: According to Family Planning Centers' philosophy, post-abortion check-ups are a good opportunity for promoting responsible procreation. The strategy for the management of the Trento Family Planning Center's users requesting an abortion led to an increase of the proportion of users who returned for the post-abortion check-up greater than is the case for other territorial Family Planning Centers.
- Published
- 2021
- Full Text
- View/download PDF
40. Rubella immunity status and the active offer of MMR/MMRV vaccination during pregnancy.
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Piffer S, Pedron M, Dal Martello M, Caciagli P, Lanzafame P, Saugo M, and Ferro A
- Subjects
- Adolescent, Adult, Female, Humans, Pregnancy, Retrospective Studies, Seroconversion, Vaccines, Combined immunology, Young Adult, Chickenpox Vaccine immunology, Measles-Mumps-Rubella Vaccine immunology, Pregnancy Complications, Infectious prevention & control, Rubella diagnosis, Rubella prevention & control, Rubella Syndrome, Congenital prevention & control
- Abstract
Introduction: The rubella test during pregnancy makes it possible to identify situations at risk of congenital rubella and those pregnant mothers who should be offered the MMR vaccine., Materials and Methods: The Authors analysed test coverage and the immunity status of pregnant mothers between 2005 and 2017, using birth attendance certificates., Results: Rubella test coverage on 61,437 pregnant mothers was 99.4%. The average proportion of susceptible subjects was 6.4%. Seroconversion was observed in 7 cases, with 1 confirmed case of congenital rubella. 32% of susceptible subjects were vaccinated, and adherence was seen to be influenced by the characteristics of the pregnant women and of the maternity unit., Conclusions: A current information flow including a number of healthcare services, is useful both for monitoring the maternity care pathway and for public health purposes.
- Published
- 2021
- Full Text
- View/download PDF
41. Prevalence of Huntington's disease in Southern Sardinia, Italy.
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Muroni A, Murru MR, Sechi M, Ercoli T, Marrosu F, Bentivoglio AR, Petracca M, Maria Scaglione CL, Soliveri P, Cocco E, Pedron M, Murgia M, Deriu M, Cuccu S, Ulgheri L, Zuccato C, and Defazio G
- Subjects
- Adult, Aged, Female, Humans, Italy epidemiology, Male, Mediterranean Islands epidemiology, Middle Aged, Prevalence, Huntington Disease epidemiology
- Abstract
Background: The frequency of Huntington's disease (HD) may vary considerably, with higher estimates in non Asian populations. In Italy, two recent studies performed in Ferrara county and Molise provided different prevalence estimates, varying from 4.2 × 10
5 to 10.8 × 105 . Here we present a study performed in the Southern part of Sardinia, a large Italian mediterranean island that is considered a genetic isolate., Methods: The study area included the two neighbouring counties of South Sardinia and Cagliari with 353,830 and 431,955 inhabitants respectively on December 31st, 2017 (prevalence date). Case-patients were ascertained through multiple sources in Sardinia and Italy., Results: We identified 54 individuals with HD, of whom 47 were alive on prevalence date. The resulting prevalence rate was 5.98 × 105 in the overall study area, however with marked variations between South Sardinia and Cagliari (9.6 × 105 vs. 3.0 × 105 , p = 0.02). In the two study areas, we found similar CAG repeat length in normal alleles (17.5 ± 2.1 vs. 17.7 ± 2.2, p = 0.5)., Conclusions: The overall prevalence of HD in Sardinia is close to the correspondent estimates in Europeans. Our findings also highlighted the possibility of local microgeographic variations in the epidemiology of HD., (Copyright © 2020 Elsevier Ltd. All rights reserved.)- Published
- 2020
- Full Text
- View/download PDF
42. Response to a Specific and Digitally Supported Training at Home for Students With Mathematical Difficulties.
- Author
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Re AM, Benavides-Varela S, Pedron M, De Gennaro MA, and Lucangeli D
- Abstract
The present study evaluated the effectiveness of a shortened, specialized, and digitally supported training program for enhancing numerical skills in primary and secondary school children with mathematical difficulty (MD). The participants ( n = 57) were randomly assigned to two groups: for the experimental group, the tasks were differentiated and adapted to each student's learning profile. Moreover, children of this group used a Web App (i.e., "I bambini contano" or "Children count" in English) for improving arithmetic fact retrieval at home; for the control group, the difficulty of the activities was graded according to the school curriculum, and this group did not use the Web App. Pre- to post-training measurements showed that children of the experimental group had an improvement significantly higher than the control group, in particular in arithmetic facts and written calculation. Moreover, a follow-up evaluation indicated that the efficacy of the experimental training program lasted up to 2 months after the intervention. The results indicate that a specialized face-to-face intervention along with a digitally supported training at home can benefit children with mathematical learning difficulties., (Copyright © 2020 Re, Benavides-Varela, Pedron, De Gennaro and Lucangeli.)
- Published
- 2020
- Full Text
- View/download PDF
43. The biophysical, molecular, and anatomical landscape of pigeon CRY4: A candidate light-based quantal magnetosensor.
- Author
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Hochstoeger T, Al Said T, Maestre D, Walter F, Vilceanu A, Pedron M, Cushion TD, Snider W, Nimpf S, Nordmann GC, Landler L, Edelman N, Kruppa L, Dürnberger G, Mechtler K, Schuechner S, Ogris E, Malkemper EP, Weber S, Schleicher E, and Keays DA
- Abstract
The biophysical and molecular mechanisms that enable animals to detect magnetic fields are unknown. It has been proposed that birds have a light-dependent magnetic compass that relies on the formation of radical pairs within cryptochrome molecules. Using spectroscopic methods, we show that pigeon cryptochrome clCRY4 is photoreduced efficiently and forms long-lived spin-correlated radical pairs via a tetrad of tryptophan residues. We report that clCRY4 is broadly and stably expressed within the retina but enriched at synapses in the outer plexiform layer in a repetitive manner. A proteomic survey for retinal-specific clCRY4 interactors identified molecules that are involved in receptor signaling, including glutamate receptor-interacting protein 2, which colocalizes with clCRY4. Our data support a model whereby clCRY4 acts as an ultraviolet-blue photoreceptor and/or a light-dependent magnetosensor by modulating glutamatergic synapses between horizontal cells and cones., (Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).)
- Published
- 2020
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44. Hybrid Breast Augmentation: A Reliable Formula for Preoperative Assessment of Fat Graft Volume Based on Implant Volume and Projection.
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Maximiliano J, Munhoz AM, Pedron M, de Oliveira ACP, Duarte DW, Neto R, Portinho CP, and Collares MVM
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- Breast diagnostic imaging, Breast surgery, Humans, Personal Satisfaction, Transplantation, Autologous, Breast Implants, Mammaplasty
- Abstract
Background: Autogenous fat grafting (AFG) is an established technique used as an adjunct to breast augmentation (BA) to redesign breast shape. Surgeons often use experience and intuition to estimate AFG volume, which can result in incorrect assessment of donor areas and unnecessary fat removal., Objectives: This aim of this study was to develop a method based on a mathematical formula, which utilizes implant volume and projection to predict AFG volume., Methods: Thirty patients (60 breasts) underwent primary hybrid BA. A software package (SketchUp) was used to simulate 3-dimensional AFG and implant volumes, which in turn were used to develop an equation for estimating AFG volume according to 3 different implant projections. The results for each group were compared, via Pearson's correlation coefficient, with the results of the clinical series., Results: All patients received Motiva Ergonomix SmoothSilk/SilkSurface implants, ranging in volume from 175 to 355 cc (mean, 265 cc), as well as an average AFG volume of 79.2 cc/breast (range, 50-110 cc). Twenty-nine patients (96.6%) were either very satisfied or satisfied during a mean follow-up of 18 months (range, 6-28 months). A high correlation was observed between the AFG performed in the cohort and predictions obtained from the formula (r = 0.938, P < 0.001)., Conclusions: The AFG volume in hybrid BA procedures can be estimated utilizing measurements based on implant volume/projection. This low-cost method can be applied to guide surgical decision-making in patients who are candidates for BA., (© 2020 The Aesthetic Society. Reprints and permission: journals.permissions@oup.com.)
- Published
- 2020
- Full Text
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45. Influence of the Generation of Motor Mental Images on Physiotherapy Treatment in Patients with Chronic Low Back Pain.
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Grande-Alonso M, Garrigos-Pedron M, Cuenca-Martinez F, Vidal-Quevedo C, Prieto-Aldana M, La Touche R, and Gil-Martinez A
- Subjects
- Adult, Cross-Sectional Studies, Disabled Persons, Exercise Therapy methods, Female, Humans, Male, Middle Aged, Self Efficacy, Chronic Pain psychology, Chronic Pain therapy, Imagination physiology, Low Back Pain psychology, Low Back Pain therapy, Motor Activity physiology
- Abstract
Background: Patients with nonspecific chronic low back pain (NCLBP) have greater difficulty generating kinesthetic and visual motor imagery., Objectives: The main aim of this study was to determine whether the ability to generate mental motor imagery (MIab) influences psychological, motor, and disability variables in patients with NCLBP. The secondary aim was to determine whether an approach based on therapeutic exercise (TE) and therapeutic education (TEd) could improve the MIab in those patients with less ability to perform it., Study Design: Cross-sectional and quasiexperimental study., Setting: Physical Therapy Unit of primary health care center in Madrid, Spain., Methods: A total of 68 patients were divided into 2 groups according to a greater (n = 34) or lesser (n = 34) MIab. Treatment was based on TEd and TE for the group with less ability to generate kinesthetic and visual motor imagery. The outcome measures were imagery requested time, self-efficacy, disability, pain intensity, lumbar strength, psychological variables, and MIab., Results: The group with lesser MIab showed lower levels of self-efficacy (P = 0.04; d, -0.47) and lower levels of lumbar strength and extension strength (P = 0.04; d, -0.46 and P = 0.02; d, -0.52, respectively). After the intervention with TE and TEd, MIab (both kinesthetic and visual) improved significantly, with a moderate to large effect size (P <= 0.01; d, -0.80 and P <= 0.01; d, -0.76, respectively), as did pain intensity, lumbar strength, disability, and psychological variables (P < 0.05), but not levels of self-efficacy (P > 0.05). Based on the results, the patients with NCLBP with lesser MIab achieved lower levels of self-efficacy and lower strength levels., Limitations: The results of this study should be interpreted with caution because of its quasiexperimental design and a bias selection., Conclusions: A clinical TE approach, coupled with a TEd program, resulted in significant improvement in MIab (both kinesthetic and visual), reduced pain intensity, increased lumbar strength, reduced disability, and improved psychological variables, but it did not significantly improve self-efficacy levels in the patients with NCLBP., Key Words: Chronic low back pain, motor imagery, disability, lumbar strength.
- Published
- 2020
46. Coverage and outcomes of antenatal tests for infections: a population based survey in the Province of Trento, Italy.
- Author
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Dalmartello M, Parazzini F, Pedron M, Pertile R, Collini L, La Vecchia C, and Piffer S
- Subjects
- Adolescent, Adult, Epidemiologic Studies, Female, Humans, Italy epidemiology, Middle Aged, Pregnancy, Pregnancy Complications, Infectious diagnosis, Young Adult, Mass Screening statistics & numerical data, Patient Acceptance of Health Care statistics & numerical data, Pregnancy Complications, Infectious epidemiology
- Abstract
Background: Rubella, syphilis, toxoplasmosis, cytomegalovirus (CMV), hepatitis B (HBV) and C (HCV), HIV, and Group B Streptococcus (GBS) infections may have very severe outcomes during pregnancy, and for this reason, monitoring of infections in pregnant women is a requirement of prenatal assistance., Aims: To describe coverage and outcome of the screening for rubella, syphilis, toxoplasmosis, CMV, HBV, HCV, HIV, and Group B Streptococcus in pregnancy in the Autonomous Province of Trento, Northern Italy (538,600 inhabitants)., Methods: We analysed the coverage and outcome of the above-mentioned screenings among women who delivered in the hospitals of the Province of Trento between 2007 and 2014 (N = 38,712). Screenings were grouped according to characteristics such as recommendation by national and local guidelines, scheduling of the tests, operating methods, and charge. We also estimated odds ratios (ORs) for missing screening for selected infections through multiple logistic regression., Results: Estimated uptake of antenatal screening was 99.7% for rubella, 99.3% for syphilis, 99.7% for toxoplasmosis, 98.1% for HIV infection, 99.0% for HBV, 98.9% for HCV, 94.0% for GBS infection, and 75.4% for CMV infection. The overall prevalence of immunity was 94.1% for rubella, 24.2% for toxoplasmosis, and 64.2% for CMV. The rate of seroconversion in pregnant women was 0.02% for rubella, 0.29% for toxoplasmosis, and 0.75% for CMV. The overall prevalence of infection was 0.94% for HBV, 0.53% for HCV, 22.3% for GBS, 0.29% for syphilis, and 0.13% for HIV. We found a significant positive association for all screening tests, between lack of testing and late first medical examination in pregnancy (ORs ranging from 1.20 to 1.66 for the first medical visit in the second trimester and ORs ranging from 1.60 to 5.88 for the first medical visit in third trimester, compared to early medical visit in the first trimester). Compared to Italian citizenship, foreign citizenship of the mother was also positively associated with absence of screening (ORs ranging from 1.30 to 1.53). A significant inverse association was observed for calendar year of delivery (ORs ranging from 0.71 to 0.97, for 1 year increment). Less educated mothers and pluriparae were also at higher risks of not being tested. Analysis of the association with mother age showed different heterogeneous effects., Conclusions: Our study indicates that the attention to screening and detecting infected cases is growing over the time. In addition, care delivered during pregnancy has a leading role in determining coverage of the examinations. Immigrant, pluriparous and less educated women need particular attention.
- Published
- 2019
- Full Text
- View/download PDF
47. Breastfeeding during the first year of life: estimates using records generated in general pediatrics.
- Author
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Pertile R, Bombarda L, Pedron M, Clivati E, and Piffer S
- Subjects
- Adolescent, Adult, Female, Humans, Infant, Infant, Newborn, Infant, Premature, Italy, Pregnancy, Time Factors, Young Adult, Breast Feeding statistics & numerical data, Mothers statistics & numerical data, Public Health
- Abstract
Background: The monitoring of breastfeeding during a child's first year of life is highly recommended. The proportion of children who are exclusively breastfed for at least six months is a strong indicator of breastfeeding promotion in the community. The objectives of the study were to survey the exclusive breastfeeding of children during the first year of life for cohorts born in Trentino (north-eastern Italy) in 2009 to 20013, to evaluate the decrease of exclusive breastfeeding at 6 months and to analyze possible relationships between the maintenance of breastfeeding up to the age of 6 months and certain maternal socio-demographic characteristics, as well as clinical aspects of the pregnancy and birth., Methods: Cohorts born in Trentino between 2009 and 2013 were studied, calculating the proportion of infants who were breastfed upon discharge from the hospital (source: data on the CedAP informative flow, that is the Italian Certificate of Delivery Assistance data-base). The data provided on the 12-Month Health Evaluation Form found in the Pediatric Health Booklet, completed by regional family pediatricians, was linked with that of the respective CedAP (96.7% linkage). The trend for exclusive breastfeeding and its monthly decrease was analyzed. The maintenance of exclusive breastfeeding until the age of 6 months was analyzed in relation to citizenship, area of residence, maternal education level and employment status, parity, single or multiple birth, infant exposure to passive smoke and attendance or non-attendance of a state-promoted childbirth preparation course. This final variable was studied solely for primiparous women, who are generally most likely to attend a childbirth preparation course. All results were adjusted for the following potential confounding variables: "birth type," "prematurity" and "feeding method upon discharge from the hospital.", Results: CedAP data revealed that 83.5% of live infants were exclusively breastfed and that this percentage decreased to 34.7% by the age of 6 months (35.4% among full-term infants and 27% among premature infants). Data from the Province of Trento demonstrates that exclusive breastfeeding up to the age of 6 months is influenced by the mother's citizenship, area of residence and education level, but not by her employment status. In addition, the study revealed a significant association with parity, passive smoke exposure and attendance of a childbirth preparation course., Conclusions: The Pediatric Health Booklet with its information on the state of health of children (in combination with data from the CedAP) offers a valid tool for monitoring breastfeeding during the first year of life. Data confirmed a decrease in the rate of breastfeeding between birth and the first month of life and between the first and sixth months of living at home. The results regarding the conditions that favour and discourage breastfeeding suggest potential public health care measures to improve children's health.
- Published
- 2019
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48. [The usefulness of emergency room data for integrated surveillance of spontaneous abortion at population level].
- Author
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Pertile R, Piffer S, Pedron M, Demonti S, Mereu L, and Tateo S
- Subjects
- Adult, Databases, Factual, Emigrants and Immigrants statistics & numerical data, Female, Health Information Systems, Humans, Italy epidemiology, Population Surveillance, Pregnancy, Young Adult, Abortion, Spontaneous epidemiology, Emergency Service, Hospital statistics & numerical data, Hospitalization statistics & numerical data
- Abstract
Objectives: to quantify and identify the proportion of miscarriages in the province of Trento (Trentino-Alto Adige Region, Northern Italy) in 2010-2016, managed exclusively at the emergency room (ER)., Design: population surveillance study., Setting and Participants: comparison between the Trentino computerized database of registration to the ER for miscarriage and the flow D-11 of the Italian National Statistics Institute (Istat) on hospitalized miscarriages in the period 2010-2016., Main Outcome Measures: for each year, the proportion of women seen at the ER for miscarriage and then hospitalized and the cases exclusively managed in ER were calculated. The two groups were compared on the basis of the following variables: age, citizenship, gestational week, calendar year, and ER of admission., Results: the proportion of miscarriages managed exclusively in ER in the province of Trento varies from 31.3% in 2010 to 60.5% in 2016. There are no differences in the proportion of hospitalization in relation to the age of women, while a higher proportion of hospitalizations was observed among foreign women compared to the Italians and in the ER of Trento compared to the peripheral ERs. A growing trend of hospitalization clearly appears with increasing gestational age, while the calendar year is inversely proportional to the increase in hospitalization., Conclusions: since the therapeutic diagnostic path of women with miscarriage has changed, it could be useful to have a representation as close as possible to the reality of the phenomenon to evaluate if an integration of the Istat D-11 flow on the cases hospitalized with those cases managed exclusively in ER is feasible or opportune. This opportunity should be considered in local, multicentre or national epidemiological studies.
- Published
- 2018
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49. [Accurate compiling of the hospital discharge records according to clinicians' perception: critical issues and perspectives].
- Author
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Mereu A, Frau S, Murgia A, Sotgiu A, Lai A, Pisano F, Marongiu F, Portoghese I, Pinna L, Lepori E, Origa P, Azara A, Castiglia P, Solinas MG, Porcheddu S, Saderi L, Argiolas F, Murtas S, Murru MG, Faedda MR, Corriga AM, Mereu NM, Spada L, Sechi GM, Massa F, Accalai S, Sanna F, Bellu C, Campagna M, Prasciolu S, Aresu C, Pedron M, Pes MA, Pisone E, Pezzi E, Contu P, and Sardu C
- Subjects
- Data Accuracy, Electronic Health Records, Humans, Italy, Medical Record Administrators education, Motivation, Qualitative Research, Data Collection methods, Hospital Records statistics & numerical data, Medical Staff, Hospital psychology, Patient Discharge statistics & numerical data, Physician Executives psychology
- Abstract
Objectives: to explore clinicians vision on hospital discharge records in order to identify useful elements to foster a more accurate compiling., Design: qualitative research with phenomenological approach., Setting and Participants: participants were selected through purposive sampling among clinicians of two hospitals located in Sardinia; the sample included 76 people (32 medical directors and 44 doctors in training)., Main Outcome Measures: identified codes for themes under investigation: vision of accurate compiling, difficulties, and proposals., Results: collected data highlighted two prevailing visions, respectively focused on the importance of an accurate compiling and on the burden of such activity. The accurate compiling is hindered by the lack of motivation and training, by the limits of the registration system and the information technology, by the distortions induced by the prominent role of the hospital discharge records in the evaluation processes. Training, timely updating of the information system accompanied by a proper cross-cultural validation process, improvement of the computer system, and activation of support services could promote more accurate compiling., Conclusions: the implementation of services, unconnected with evaluation and control processes, dedicated to training and support in the compiling of the hospital discharge records and in the conduction of related epidemiological studies would facilitate the compliance to the compilation. Such services will make tangible the benefits obtainable from this registration system, increasing skills, motivation, ownership, and facilitating greater accuracy in compiling.
- Published
- 2018
- Full Text
- View/download PDF
50. [Antenatal course attendance among primiparous mothers, with physiological pregnancy and birth at term in Trentino (Northern Italy): characteristics of non-attender women and benefits among attender women in pregnancy behaviours, type of birth delivery and neonatal outcomes].
- Author
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Pertile R, Pedron M, Berlanda M, and Piffer S
- Subjects
- Adolescent, Adult, Emigrants and Immigrants statistics & numerical data, Female, Gravidity, Health Behavior, Humans, Infant, Newborn, Italy, Measles Vaccine, Mothers statistics & numerical data, Patient Participation, Pregnancy, Pregnancy Outcome, Pregnancy, Multiple statistics & numerical data, Socioeconomic Factors, Term Birth, Vaccination statistics & numerical data, Young Adult, Mothers psychology, Prenatal Education statistics & numerical data
- Abstract
Objective: to outline the attendance rate of antenatal classes (ANCs) among women resident in Trentino Region (North-Eastern Italy) during the period 2000-2012; to identify the main sociodemographic characteristics of women who do not attend ANCs and to measure the effectiveness of ANCs attendance., Design: cohort study with a retrospective data collection., Setting and Participants: by the computerised database of Trentino Certificates of delivery care, primiparous mothers living in Trentino presenting a physiological pregnancy and birth at term (≥37 weeks of gestation) were selected. Temporal trends of ANCs attendance were also studied for all mothers living in Trentino, all primiparous residents, all multiparous residents and all residents with foreign citizenship., Main Outcome Measures: possible associations between the probability of not attending ANCs and sociodemographic variables concerning mothers were analysed: age, professional status, educational level, marital status, citizenship and residence in an area served by a maternal and child health (MCH) clinic or not. Significant relationships between ANCs attendance and variables related to course of pregnancy, childbirth and neonatal outcomes were identified., Results: ANCs coverage has a statistically significant increasing trend over time for each group of women living in Trentino. Among the selected primiparous pregnant women, the principal barriers to ANCs access are being foreign, having an age ≤30 years, in particular ≤20 years, being housewives or unemployed, presenting a medium-low educational level, and residing in an area not served by a MCH clinic. ANCs-not-attending women show a lower awareness of the importance of performing serological tests for Syphilis and Cytomegalo-virus and they declare smoking in pregnancy. Benefits of ANCs attendance do not affect neonatal outcomes, but they concern a higher probability of vaginal birth and a higher breastfeeding predisposition., Conclusion: data about ANCs attendance in Trentino Region appear higher than other national-regional studies. However, there are significant differences in access to ANCs regarding women's sociodemographic characteristics and resources distribution and MCH clinics measurement. In Italy, an evaluation about the accessibility of MCH clinics and their functioning criteria is desirable, focusing on marketing practices towards lower classes women. In Trentino, virtuosos MCH clinics have introduced elastic times in the ANCs planning and they have involved cultural mediators and private gynaecologists. Younger pregnant women are included in the ANCs after a preliminary meeting or by individual paths.
- Published
- 2015
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