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Your search keyword '"Pedrazzi, João Francisco"' showing total 17 results
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17 results on '"Pedrazzi, João Francisco"'

3. Novel Proline Transporter Inhibitor (LQFM215) Presents Antipsychotic Effect in Ketamine Model of Schizophrenia

Author

Carvalho, Gustavo Almeida, Chiareli, Raphaela Almeida, Pedrazzi, João Francisco Cordeiro, Silva-Amaral, Danyelle, da Rocha, André Luís Batista, Oliveira-Lima, Onésia Cristina, Lião, Luciano Morais, de Souza-Fagundes, Elaine Maria, Schildknecht, Stefan, Leist, Marcel, Del-Bel, Elaine Aparecida, Gomez, Renato Santiago, Birbrair, Alexander, Menegatti, Ricardo, and Pinto, Mauro Cunha Xavier

Published
2024
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5. Distinct sex-dependent behavioral responses induced by two positive allosteric modulators of alpha 5 subunit-containing GABAA receptors

Author

Souza, Adriana Jesus, Cortez, Isadora L., Silva, Nicole R., Pedrazzi, João Francisco C., Domingos, Luana B., Braga, Matheus Silva, Santos-Silva, Thamyris, Del-Bel, Elaine A., Resstel, Leonardo B.M., Li, Guanguan, Mian, Md Yeunus, Sharmin, Dishary, Guimarães, Francisco S., Cook, James M., and Gomes, Felipe V.

Published
2022
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6. Research and Clinical Practice Involving the Use of Cannabis Products, with Emphasis on Cannabidiol: A Narrative Review.

Author

Simei, João Luís Q., Souza, José Diogo R., Pedrazzi, João Francisco, Guimarães, Francisco S., Campos, Alline Cristina, Zuardi, Antônio, Hallak, Jaime Eduardo C., and Crippa, José Alexandre S.

Subjects
MEDICAL scientists, CURRENT good manufacturing practices, CANNABINOIDS, PHARMACOLOGY, DRUG development, CANNABIDIOL
Abstract

Background: Emerging evidence supports cannabidiol (CBD) as a promising therapeutic compound for various health conditions, despite its approval as a medication (product for medical purposes) remaining restricted to a limited range of clinical indications. Simultaneously, the regulation of cannabis-derived products for medicinal and recreational use has expanded their global market availability to meet local community demands. This scenario presents a complex challenge for clinicians, researchers, and industry, as the global appeal of therapeutic uses of CBD is growing more rapidly than the scientific evidence supporting its safety and effectiveness. Outcomes: A narrative review was conducted to discuss the best evidence regarding the pharmacological profile of CBD, its efficacy, and safety within the context of regulation and perspectives on the development of new cannabinoid-based drugs. Key articles addressing the various facets of this issue were selected for comprehensive analysis. Conclusions: Clinicians and researchers may face unique challenges in understanding the pharmacological profile of CBD and the prospects for developing its clinical indications, given the heterogeneity of clinical terminologies and the quality and composition of cannabis-based medical products available on the market. More basic and clinical research that complies with regulatory agencies' testing guidelines, such as good manufacturing practices (GMPs), good laboratory practices (GLPs), and good clinical practices (GCPs), is needed to obtain approval for CBD or any other cannabinoid as a therapeutic for broader clinical indications. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Chapter Four - A journey through cannabidiol in Parkinson’s disease

Author

Del-Bel, Elaine, Barros-Pereira, Nubia, Moraes, Rafaela Ponciano de, Mattos, Bianca Andretto de, Alves-Fernandes, Thaís Antonia, Abreu, Lorena Borges de, Nascimento, Glauce Crivelaro, Escobar-Espinal, Daniela, Pedrazzi, João Francisco Cordeiro, Jacob, Gabrielle, Milan, Bruna A., Bálico, Gabriela Gonçalves, and Antonieto, Livia Rodrigues

Published
2024
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13. Correction: Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects

Author

Breuer, Aviva, primary, Haj, Christeene G., additional, Fogaça, Manoela V., additional, Gomes, Felipe V., additional, Silva, Nicole Rodrigues, additional, Pedrazzi, João Francisco, additional, Del Bel, Elaine A., additional, Hallak, Jaime C., additional, Crippa, José A., additional, Zuardi, Antonio W., additional, Mechoulam, Raphael, additional, and Guimarães, Francisco S., additional

Published
2016
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14. Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects

Author

Breuer, Aviva, primary, Haj, Christeene G., additional, Fogaça, Manoela V., additional, Gomes, Felipe V., additional, Silva, Nicole Rodrigues, additional, Pedrazzi, João Francisco, additional, Del Bel, Elaine A., additional, Hallak, Jaime C., additional, Crippa, José A., additional, Zuardi, Antonio W., additional, Mechoulam, Raphael, additional, and Guimarães, Francisco S., additional

Published
2016
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