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2 results on '"Pediatric thrombocytopenia"'

1. Management of Chronic Childhood Immune Thrombocytopenic Purpura: AIEOP Consensus Guidelines.

Author

De Mattia, Domenico, Del Vecchio, Giovanni Carlo, Russo, Giovanna, De Santis, Attilio, Ramenghi, Ugo, Notarangelo, Lucia, Jankovic, Momcilo, Molinari, Angelo Claudio, Zecca, Marco, Nobili, Bruno, and Giordano, Paola

Subjects
*PURPURA (Pathology), *THROMBOCYTOPENIA, *MEDICAL care, *PEDIATRICS, *HEMATOLOGISTS
Abstract

Background/Objective: The management of chronic childhood idiopathic thrombocytopenic purpura (ITP) is distinct from acute ITP. Similar to the publication on acute ITP guidelines, the AIEOP (Associazione Italiana di Ematologia e Oncologia Pediatrica) considered it appropriate to develop consensus guidelines for chronic childhood ITP to provide useful and shared information for physicians, healthcare professionals, parents and patients. Design/Methods: A preliminary, evidence-based document issued by a select group of AIEOP pediatric hematologists was discussed, modified and approved during a Consensus Conference according to procedures previously validated by the AIEOP Board. Results: The guidelines give prominence to the periodical reevaluation of all the etiological hypotheses of thrombocytopenia in relation to its clinical condition. The majority of chronic ITP children do not require treatment, especially if bleeding is absent or minimal. The treatment decision depends on several factors other than the platelet count, and treatment options are suggested in relation to the therapeutic scenarios. Recommendations are given regarding support for surgery, particular hemorrhagic conditions, daily activities/sports, as well as for vaccines and drugs. Experimental treatments are also discussed. Copyright © 2009 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2010
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2. Management of Chronic Childhood Immune Thrombocytopenic Purpura: AIEOP Consensus Guidelines

Author

De Mattia D, Del Vecchio GC, Russo G, De Santis A, Ramenghi U, Notarangelo L, Jankovic M, Molinari AC, Zecca M, Nobili B, Giordano P, AIEOP ITP Study Group, Acquaviva A, Amendola G, Baronci C, Binda S, Bisogno G, Bussetti C, Ciliberti A, Citterio M, Del Principe D, Farruggia P, Ladogana S, Magro S, Masera G, Menichelli A, Nardi M, Parodi E, Tucci F, Vimercati C., PESSION, ANDREA, DE MATTIA, D, DEL VECCHIO, Gc, Russo, G, DE SANTIS, A, Ramenghi, U, Notarangelo, L, Jankovic, M, Molinari, Ac, Zecca, M, Nobili, Bruno, Giordano, P, AIEOP ITP STUDY, Group, De Mattia D, Del Vecchio GC, Russo G, De Santis A, Ramenghi U, Notarangelo L, Jankovic M, Molinari AC, Zecca M, Nobili B, Giordano P, and AIEOP-ITP Study Group,Acquaviva A, Amendola G, Baronci C, Binda S, Bisogno G, Bussetti C, Ciliberti A, Citterio M, Del Principe D, Farruggia P, Ladogana S, Magro S, Masera G, Menichelli A, Nardi M, Parodi E, Pession A, Tucci F, Vimercati C.

Subjects
Pediatrics, medicine.medical_specialty, Platelet count, Adolescent, Consensus Development Conferences as Topic, Prednisolone, Rho(D) Immune Globulin, medicine.medical_treatment, conta piastrinica, Splenectomy, Platelet Transfusion, management of pediatric thrombocytopenia, idiopathic thrombocytopenic purpura, platelet count, trattamento della piastrinopenia pediatrica, porpora trombocitopenica idiopatica, Immune system, immune system diseases, hemic and lymphatic diseases, medicine, Pediatric thrombocytopenia, Humans, Platelet, Idiopathic thrombocytopenic purpura, Management of pediatric thrombocytopenia, Thrombocytopenia, Child, Purpura, Thrombocytopenic, Idiopathic, biology, business.industry, Immunoglobulins, Intravenous, Infant, Hematology, General Medicine, medicine.disease, Thrombocytopenic purpura, Purpura, Chronic disease, Platelet transfusion, Child, Preschool, Chronic Disease, biology.protein, Antibody, medicine.symptom, business, Idiopathic thrombocytopenic purpura, Management of pediatric thrombocytopenia, Pediatric thrombocytopenia, Platelet count, Thrombocytopenia
Abstract

Background/Objective: The management of chronic childhood idiopathic thrombocytopenic purpura (ITP) is distinct from acute ITP. Similar to the publication on acute ITP guidelines, the AIEOP (Associazione Italiana di Ematologia e Oncologia Pediatrica) considered it appropriate to develop consensus guidelines for chronic childhood ITP to provide useful and shared information for physicians, healthcare professionals, parents and patients. Design/Methods: A preliminary, evidence-based document issued by a select group of AIEOP pediatric hematologists was discussed, modified and approved during a Consensus Conference according to procedures previously validated by the AIEOP Board. Results: The guidelines give prominence to the periodical reevaluation of all the etiological hypotheses of thrombocytopenia in relation to its clinical condition. The majority of chronic ITP children do not require treatment, especially if bleeding is absent or minimal. The treatment decision depends on several factors other than the platelet count, and treatment options are suggested in relation to the therapeutic scenarios. Recommendations are given regarding support for surgery, particular hemorrhagic conditions, daily activities/sports, as well as for vaccines and drugs. Experimental treatments are also discussed.

Published
2010

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