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8 results on '"Pedersen, Ole Birger Vestager"'

1. A genome-wide association study of social trust in 33,882 Danish blood donors

Author

Sequeros, Celia Burgos, Hansen, Thomas Folkmann, Westergaard, David, Louloudis, Ioannis, Kalamajski, Sebastian, Röder, Timo, Rohde, Palle Duun, Schwinn, Michael, Clemmensen, Line Harder, Didriksen, Maria, Nyegaard, Mette, Hjalgrim, Henrik, Nielsen, Kaspar René, Bruun, Mie Topholm, Ostrowski, Sisse Rye, Erikstrup, Christian, Mikkelsen, Susan, Sørensen, Erik, Pedersen, Ole Birger Vestager, Brunak, Søren, Banasik, Karina, and Giordano, Giuseppe Nicola

Published
2024
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2. Long-term detection of SARS-CoV-2 antibodies after infection and risk of re-infection

Author

Hønge, Bo Langhoff, Hindhede, Lotte, Kaspersen, Kathrine Agergård, Harritshøj, Lene Holm, Mikkelsen, Susan, Holm, Dorte Kinggaard, Nilsson, Anna Christine, Sækmose, Susanne Gjørup, Sørensen, Erik, Aagaard, Bitten, Hjalgrim, Henrik, Jørgensen, Charlotte Sværke, Krause, Tyra Grove, Ullum, Henrik, Pedersen, Ole Birger Vestager, Ostrowski, Sisse Rye, and Erikstrup, Christian

Published
2022
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3. Clonal hematopoiesis and COVID-19 hospitalization in Danish adults

Author

Burgos Sequeros, Celia, Tulstrup, Morten, Bliddal, Sofie, Sørensen, Karina Meden, Nissen, Ioanna, Rezahosseini, Omid, Brooks, Patrick Terrence, Feenstra, Bjarke, Gang, Anne Ortved, Geller, Frank, Hald, Annemette, Harboe, Zitta Barrella, Helleberg, Marie, Jespersen, Jakob S., Lebech, Anne Mette, Lindegaard, Birgitte, Mogensen, Trine H., Møller, Maria Elizabeth Engel, Nielsen, Claus Henrik, Niemann, Carsten Utoft, Podlekareva, Daria, Sejdic, Adin, Sørensen, Erik, Teglgaard, Rebecca Svanberg, Tommerup, Niels, Weis, Nina, Brunak, Søren, Pedersen, Ole Birger Vestager, Banasik, Karina, Feldt-Rasmussen, Ulla, Nielsen, Susanne Dam, Ostrowski, Sisse Rye, Grønbæk, Kirsten, Burgos Sequeros, Celia, Tulstrup, Morten, Bliddal, Sofie, Sørensen, Karina Meden, Nissen, Ioanna, Rezahosseini, Omid, Brooks, Patrick Terrence, Feenstra, Bjarke, Gang, Anne Ortved, Geller, Frank, Hald, Annemette, Harboe, Zitta Barrella, Helleberg, Marie, Jespersen, Jakob S., Lebech, Anne Mette, Lindegaard, Birgitte, Mogensen, Trine H., Møller, Maria Elizabeth Engel, Nielsen, Claus Henrik, Niemann, Carsten Utoft, Podlekareva, Daria, Sejdic, Adin, Sørensen, Erik, Teglgaard, Rebecca Svanberg, Tommerup, Niels, Weis, Nina, Brunak, Søren, Pedersen, Ole Birger Vestager, Banasik, Karina, Feldt-Rasmussen, Ulla, Nielsen, Susanne Dam, Ostrowski, Sisse Rye, and Grønbæk, Kirsten

Published
2024

4. Estimation of SARS-CoV-2 Infection Fatality Rate by Age and Comorbidity Status Using Antibody Screening of Blood Donors during the COVID-19 Epidemic in Denmark

Author

Kaspersen, Kathrine Agergård, Hindhede, Lotte, Boldsen, Jens Kjærgaard, Mikkelsen, Susan, Vestergaard, Lasse Skafte, Berthelsen, Ann Sofie Nicole, Moustsen-Helms, Ida Rask, Holm, Dorte Kinggaard, Nilsson, Anna Christine, Sækmose, Susanne Gjørup, Sørensen, Erik, Harritshøj, Lene Holm, Aagaard, Bitten, Hjalgrim, Henrik, Lillevang, Søren Thue, Jørgensen, Charlotte Sværke, Krause, Tyra Grove, Ullum, Henrik, Pedersen, Ole Birger Vestager, Ostrowski, Sisse Rye, Erikstrup, Christian, Kaspersen, Kathrine Agergård, Hindhede, Lotte, Boldsen, Jens Kjærgaard, Mikkelsen, Susan, Vestergaard, Lasse Skafte, Berthelsen, Ann Sofie Nicole, Moustsen-Helms, Ida Rask, Holm, Dorte Kinggaard, Nilsson, Anna Christine, Sækmose, Susanne Gjørup, Sørensen, Erik, Harritshøj, Lene Holm, Aagaard, Bitten, Hjalgrim, Henrik, Lillevang, Søren Thue, Jørgensen, Charlotte Sværke, Krause, Tyra Grove, Ullum, Henrik, Pedersen, Ole Birger Vestager, Ostrowski, Sisse Rye, and Erikstrup, Christian

Abstract

Background: Studies presenting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) for healthy individuals are warranted. We estimate IFR by age and comorbidity status using data from a large serosurvey among Danish blood donors and nationwide data on coronavirus disease 2019 (COVID-19) mortality. Methods: Danish blood donors aged 17-69 years donating blood October 2020-February 2021 were tested with a commercial SARS-CoV-2 total antibody assay. IFR was estimated for weeks 11 to 42, 2020 and week 43, 2020 to week 6, 2021, representing the first 2 waves of COVID-19 epidemic in Denmark. Results: In total, 84944 blood donors were tested for antibodies. The seroprevalence was 2% in October 2020 and 7% in February 2021. Among 3898039 Danish residents aged 17-69 years, 249 deaths were recorded. The IFR was low for people <51 years without comorbidity during the 2 waves (combined IFR=3.36 per 100000 infections). The IFR was below 3‰ for people aged 61-69 years without comorbidity. IFR increased with age and comorbidity but declined from the first to second wave. Conclusions: In this nationwide study, the IFR was very low among people <51 years without comorbidity.

Published
2022

5. Estimation of SARS-CoV-2 Infection Fatality Rate by Age and Comorbidity Status Using Antibody Screening of Blood Donors During the COVID-19 Epidemic in Denmark

Author

Kaspersen, Kathrine Agergård, primary, Hindhede, Lotte, additional, Boldsen, Jens Kjærgaard, additional, Mikkelsen, Susan, additional, Vestergaard, Lasse Skafte, additional, Berthelsen, Ann-Sofie Nicole, additional, Moustsen-Helms, Ida Rask, additional, Holm, Dorte Kinggaard, additional, Nilsson, Anna Christine, additional, Sækmose, Susanne Gjørup, additional, Sørensen, Erik, additional, Harritshøj, Lene Holm, additional, Aagaard, Bitten, additional, Hjalgrim, Henrik, additional, Lillevang, Søren Thue, additional, Jørgensen, Charlotte Sværke, additional, Krause, Tyra Grove, additional, Ullum, Henrik, additional, Pedersen, Ole Birger Vestager, additional, Ostrowski, Sisse Rye, additional, and Erikstrup, Christian, additional

Published
2021
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6. Estimation of SARS-CoV-2 Infection Fatality Rate by Real-time Antibody Screening of Blood Donors

Author

Erikstrup, Christian, Hother, Christoffer Egeberg, Pedersen, Ole Birger Vestager, Mølbak, Kåre, Skov, Robert Leo, Holm, Dorte Kinggaard, Saekmose, Susanne Gjorup, Nilsson, Anna Christine, Brooks, Patrick Terrence, Boldsen, Jens Kjaergaard, Mikkelsen, Christina, Gybel-Brask, Mikkel, Sørensen, Erik, Dinh, Khoa Manh, Mikkelsen, Susan, Moller, Bjarne Kuno, Haunstrup, Thure, Harritshøj, Lene, Jensen, Bitten Aagaard, Hjalgrim, Henrik, Lillevang, Søren Thue, Ullum, Henrik, Erikstrup, Christian, Hother, Christoffer Egeberg, Pedersen, Ole Birger Vestager, Mølbak, Kåre, Skov, Robert Leo, Holm, Dorte Kinggaard, Saekmose, Susanne Gjorup, Nilsson, Anna Christine, Brooks, Patrick Terrence, Boldsen, Jens Kjaergaard, Mikkelsen, Christina, Gybel-Brask, Mikkel, Sørensen, Erik, Dinh, Khoa Manh, Mikkelsen, Susan, Moller, Bjarne Kuno, Haunstrup, Thure, Harritshøj, Lene, Jensen, Bitten Aagaard, Hjalgrim, Henrik, Lillevang, Søren Thue, and Ullum, Henrik

Abstract

Background. The pandemic due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has tremendous consequences for our societies. Knowledge of the seroprevalence of SARS-CoV-2 is needed to accurately monitor the spread of the epidemic and to calculate the infection fatality rate (IFR). These measures may help the authorities make informed decisions and adjust the current societal interventions. The objective was to perform nationwide real-time seroprevalence surveying among blood donors as a tool to estimate previous SARS-CoV-2 infections and the population-based IFR.Methods. Danish blood donors aged 17-69 years giving blood 6 April to 3 May were tested for SARS-CoV-2 immunoglobulin M and G antibodies using a commercial lateral flow test. Antibody status was compared between geographical areas, and an estimate of the IFR was calculated. Seroprevalence was adjusted for assay sensitivity and specificity taking the uncertainties of the test validation into account when reporting the 95% confidence intervals (CIs).Results. The first 20 640 blood donors were tested, and a combined adjusted seroprevalence of 1.9% (95% CI, .8-2.3) was calculated. The seroprevalence differed across areas. Using available data on fatalities and population numbers, a combined IFR in patientsConclusions. The IFR was estimated to be slightly lower than previously reported from other countries not using seroprevalence data. The IFR is likely severalfold lower than the current estimate. We have initiated real-time nationwide anti-SARS-CoV-2 seroprevalence surveying of blood donations as a tool in monitoring the epidemic.

Published
2021

7. Estimation of SARS-CoV-2 Infection Fatality Rate by Real-time Antibody Screening of Blood Donors

Author

Erikstrup, Christian, primary, Hother, Christoffer Egeberg, additional, Pedersen, Ole Birger Vestager, additional, Mølbak, Kåre, additional, Skov, Robert Leo, additional, Holm, Dorte Kinggaard, additional, Sækmose, Susanne Gjørup, additional, Nilsson, Anna Christine, additional, Brooks, Patrick Terrence, additional, Boldsen, Jens Kjærgaard, additional, Mikkelsen, Christina, additional, Gybel-Brask, Mikkel, additional, Sørensen, Erik, additional, Dinh, Khoa Manh, additional, Mikkelsen, Susan, additional, Møller, Bjarne Kuno, additional, Haunstrup, Thure, additional, Harritshøj, Lene, additional, Jensen, Bitten Aagaard, additional, Hjalgrim, Henrik, additional, Lillevang, Søren Thue, additional, and Ullum, Henrik, additional

Published
2020
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8. Clonal hematopoiesis and COVID-19 hospitalization in Danish adults.

Author

Sequeros CB, Tulstrup M, Bliddal S, Sørensen KM, Nissen I, Rezahosseini O, Brooks PT, Feenstra B, Gang AO, Geller F, Hald A, Harboe ZB, Helleberg M, Jespersen JS, Lebech AM, Lindegaard B, Mogensen TH, Møller MEE, Nielsen CH, Niemann CU, Podlekareva D, Sejdic A, Sørensen E, Teglgaard RS, Tommerup N, Weis N, Brunak S, Pedersen OBV, Banasik K, Feldt-Rasmussen U, Nielsen SD, Ostrowski SR, and Grønbæk K

Abstract

Competing Interests: Kirsten Grønbæk has received research funding and/or consultancy fees from Janssen Pharma and GSK. Carsten Utoft Niemann has received research funding and/or consultancy fees from Abbvie, AstraZeneca, Janssen, Octapharma, Beigene, Genmab, CSL Behring, Takeda, Lilly, and MSD. Anne‐Mette Lebech has received unrestricted research grant from Gilead and consultancy fees from GSK, MSD, and Pfizer.

Published
2024
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