1. Mediastinitis secondary to invasive infection by group A Streptococcus in Spain.
- Author
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Mellado-Sola, I., Cobo-Vázquez, E., Calvo-Fernandez, A., Cervantes, E., Coca, A., Calderón-Llopis, B., Saavedra-Lozano, J., Calvo, C., PedGAS-net group, Grandioso, D., Aguilera, D., Rincón, E., Jové, A., Cercenado, E., Sanz Santaeufemia, F. J., Gónzalez, M. J., Sánchez, E., Blázquez, D., Manzanares, A., and Reinoso, T.
- Subjects
MEDIASTINITIS ,STREPTOCOCCAL diseases ,BACTERIAL diseases ,COMPLEX organizations ,DISEASE outbreaks ,STREPTOCOCCUS - Abstract
This study describes 5 mediastinitis cases secondary to invasive group A Streptococcus (iGAS) disease in a recent outbreak in Spain. Among 398 iGAS cases between January 2019—March 2023, 5 (1.3%) were mediastinitis, 4 occurring in December 2022, all secondary to pneumonia or deep neck infection. We outline the clinical outcome with a review of the scarce pediatric literature. Conclusion: mediastinistis is a rare but severe complication of iGAS and a high level of suspicion is required to diagnose it. What is Known: • Group A Streptococcus can cause invasive and severe infections in children. • Mediastinitis is a severe complication from some bacterial infections, mainly secondary due to deep-neck abscesses. What is New: • Mediastinitis is an unrecognized complication due to an invasive group A Streptococcus (iGAS) infection. • In cases of a deep-neck abscess or complicated pneumonia a high clinical suspicion of iGAS mediastinitis is required, especially when the clinical course is not favorable. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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