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15 results on '"Pecoraro, Claudia"'

5. Esploracconto per Roma - PalindRoma, il teatro solare delle architetture romane - in ROME nome plurale di città #2 a cura di Giorgio de Finis e Carmine Benincasa

Author

Panunzi, Stefano, DE FINIS, Giorgio, Carmine, Benincasa, Allegri, Giuseppe, Anania, Giulia, Baglivo, Carmelo, Barone, Tiziana, Bego, Nensi, Campagna, Janila, Canevacci, Massimo, Careri, Francesco, Carrano, Eleonora, Celestini, Ascanio, Cellamare, Carlo, Pongide, Cobol, Damiani, Serena, di raimo antonino, di vetta paolo, Ercolani, Adriano, Ferri, Patrizia, Finelli, Roberto, Finucci, Fabrizio, Grazioli, Margherita, Gussoni, Alice, Infante, Carlo, Marinelli, Danilo, Mazzone, Massimo, Meogrossi, Piero, Mina, Gabriele, Pasquali, Michela, Pecoraro, Claudia, Prati, Carlo, prestinenza puglisi luigi, Purini, Franco, Ranaldi, Irene, Roca, Anton, Romito, Lorenzo, Saviani, Lucio, Simoncini, Stefano, Sina, Ylenia, and capdevila pablo martinez

Subjects
rigenerazione urbana, narrazione urbana, rigenerazione urbana, narrazione urbana
Published
2021

9. Achromobacter xylosoxidansGenomic Characterization and Correlation of Randomly Amplified Polymorphic DNA Profiles of Cystic Fibrosis Patients

Author

Magni, Annarita, Trancassini, Maria, Varesi, Paola, Iebba, Valerio, Curci, Anna, Pecoraro, Claudia, Cimino, Giuseppe, Schippa, Serena, and Quattrucci, Serena

Abstract

ABSTRACTAchromobacter xylosoxidansis an emerging pathogen increasingly being isolated from respiratory samples of cystic fibrosis (CF) patients. Its role and clinical significance in lung pathogenesis have not yet been clarified. The aim of the present study was to genetically characterize A. xylosoxidansstrains isolated from CF patients by use of randomly amplified polymorphic DNA (RAPD) profiles and to look for a possible correlation between RAPD profiles and the patients' clinical features, such as their spirometry values, the presence of concomitant chronic bacterial flora at the time of isolation, and the persistent or intermittent presence of A. xylosoxidansstrains. A set of 106 strains of A. xylosoxidanswere typed by RAPD analysis, and their profiles were analyzed by agglomerative hierarchical classification (AHC) and associated with the patient characteristics mentioned above by factorial discriminant analysis (FDA). The overall results obtained in this study showed that (i) there is a marked genetic relationship between strains isolated from the same patients at different times, (ii) characteristic RAPD profiles are associated with different predicted classes for forced expiratory volume in 1 s (FEV1%), (iii) some characteristic RAPD profiles are associated with different concomitant chronic flora (CCF) profiles, and (iv) there is a significant division of RAPD profiles into “persistent strains” and “intermittent strains” of A. xylosoxidans. These findings seem to imply that the lung habitats found in CF patients are capable of shaping and selecting the colonizing bacterial flora, as seems to be the case for the A. xylosoxidansstrains studied.

Published
2010
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12. Dimer and cluster approach for the evaluation of electronic couplings governing charge transport: Application to two pentacene polymorphs

Author

Claudia Pecoraro, Fabrizia Negri, Sofia Canola, Canola, Sofia, Pecoraro, Claudia, and Negri, Fabrizia

Subjects
genetic structures, General Physics and Astronomy, 02 engineering and technology, Quantum-chemistry, 010402 general chemistry, 01 natural sciences, Quantum chemistry, Pentacene, Physics and Astronomy (all), chemistry.chemical_compound, Atomic orbital, Computational chemistry, Embedding effect, Cluster (physics), Molecule, Molecular orbital, Organic semiconductor, Physical and Theoretical Chemistry, Anisotropy, Electronic coupling, Chemistry, 021001 nanoscience & nanotechnology, Charge transport anisotropy, 0104 chemical sciences, Chemical physics, 0210 nano-technology
Abstract

Hole transport properties are modeled for two polymorphs of pentacene: the single crystal polymorph and the thin film polymorph relevant for organic thin-film transistor applications. Electronic couplings are evaluated in the standard dimer approach but also considering a cluster approach in which the central molecule is surrounded by a large number of molecules quantum-chemically described. The effective electronic couplings suitable for the parametrization of a tight-binding model are derived either from the orthogonalization scheme limited to HOMO orbitals and from the orthogonalization of the full basis of molecular orbitals. The angular dependent mobilities estimated for the two polymorphs using the predicted pattern of couplings display different anisotropy characteristics as suggested from experimental investigations.

Published
2016
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13. Modeling p-type charge transport in thienoacene analogs of pentacene

Author

Fabrizia Negri, Sofia Canola, Claudia Pecoraro, Canola, Sofia, Pecoraro, Claudia, and Negri, Fabrizia

Subjects
Quantum-chemical calculation, Chemistry, Analytical chemistry, Stacking, 02 engineering and technology, Charge transport, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Molecular physics, 0104 chemical sciences, Pentacene, Organic semiconductor, Partial charge, chemistry.chemical_compound, Electric field, Charge carrier, Kinetic Monte Carlo, Thienoacene, Physical and Theoretical Chemistry, 0210 nano-technology, Quantum
Abstract

The charge transport properties of two fused-ring thienoacenes, (a) the syn-isomer of dibenzo-thieno-dithiophene (DBTDT), packing in the solid state with a π–π stacking arrangement and also known as bis-benzo-thieno-thiophene (BBTT) and (b) C6-DBTDT, an alkylated derivative, packing in the more conventional herring-bone arrangement, are investigated computationally in the framework of the non-adiabatic hopping mechanism. Charge transfer rate constants are computed within the Marcus–Levich–Jortner formalism including a single effective mode treated quantum mechanically and are injected in a kinetic Monte Carlo scheme to propagate the charge carrier in the crystal. Charge mobilities are computed at room temperature with and without the influence of an electric field and are shown to compare very well with the measured mobilities in single-crystal devices. Both systems show an almost 1D charge transport with C6-DBTDT displaying about a ten times larger mobility value, in agreement with experiment. It is shown that the role of the HOMO-1 orbital is not relevant for BBTT, while it might contribute to a more marked 2D charge transport character for C6-DBTDT.

Published
2016
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14. Achromobacter xylosoxidans genomic characterization and correlation of randomly amplified polymorphic DNA profiles with relevant clinical features [corrected] of cystic fibrosis patients.

Author

Magni A, Trancassini M, Varesi P, Iebba V, Curci A, Pecoraro C, Cimino G, Schippa S, and Quattrucci S

Subjects
Achromobacter denitrificans isolation & purification, Adolescent, Adult, Child, Preschool, Cluster Analysis, DNA, Bacterial genetics, Female, Genotype, Humans, Male, Molecular Epidemiology, Sputum microbiology, Young Adult, Achromobacter denitrificans classification, Achromobacter denitrificans genetics, Bacterial Typing Techniques methods, Cystic Fibrosis complications, DNA Fingerprinting methods, Gram-Negative Bacterial Infections microbiology, Random Amplified Polymorphic DNA Technique methods
Abstract

Achromobacter xylosoxidans is an emerging pathogen increasingly being isolated from respiratory samples of cystic fibrosis (CF) patients. Its role and clinical significance in lung pathogenesis have not yet been clarified. The aim of the present study was to genetically characterize A. xylosoxidans strains isolated from CF patients by use of randomly amplified polymorphic DNA (RAPD) profiles and to look for a possible correlation between RAPD profiles and the patients' clinical features, such as their spirometry values, the presence of concomitant chronic bacterial flora at the time of isolation, and the persistent or intermittent presence of A. xylosoxidans strains. A set of 106 strains of A. xylosoxidans were typed by RAPD analysis, and their profiles were analyzed by agglomerative hierarchical classification (AHC) and associated with the patient characteristics mentioned above by factorial discriminant analysis (FDA). The overall results obtained in this study showed that (i) there is a marked genetic relationship between strains isolated from the same patients at different times, (ii) characteristic RAPD profiles are associated with different predicted classes for forced expiratory volume in 1 s (FEV1%), (iii) some characteristic RAPD profiles are associated with different concomitant chronic flora (CCF) profiles, and (iv) there is a significant division of RAPD profiles into "persistent strains" and "intermittent strains" of A. xylosoxidans. These findings seem to imply that the lung habitats found in CF patients are capable of shaping and selecting the colonizing bacterial flora, as seems to be the case for the A. xylosoxidans strains studied.

Published
2010
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15. Emerging cystic fibrosis pathogens: incidence and antimicrobial resistance.

Author

Magni A, Giordano A, Mancini C, Pecoraro C, Varesi P, Quattrucci S, and Trancassini M

Subjects
Achromobacter drug effects, Adolescent, Burkholderia cepacia complex drug effects, Cystic Fibrosis epidemiology, Gram-Negative Bacterial Infections microbiology, Humans, Incidence, Italy epidemiology, Microbial Sensitivity Tests, Xanthomonadaceae drug effects, Anti-Bacterial Agents pharmacology, Cystic Fibrosis microbiology, Drug Resistance, Bacterial, Gram-Negative Bacterial Infections epidemiology
Abstract

We examined the frequency of isolation and the antimicrobial resistance of Burkholderia cepacia complex, Stenotrophomonas maltophilia and Achromobacter xylosoxidans in cystic fibrosis patients from 2000 to 2004. Strains susceptibility to tobramycin, piperacillin/tazobactam, imipenem, gentamicin, ciprofloxacin and ceftazidime was determined by disc diffusion assay. B. cepacia complex showed a very high resistance also to ciprofloxacin reaching 100% in 2004. S. maltophilia and A. xvylosoxidans showed high rates of antimicrobial resistance both aminoglycoside and ciprofloxacin. It is very important to monitor the percentage of isolation of these species over time to verify strains resistance to antibiotics and also to test new combinations of antimicrobial agents.

Published
2007

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