Search

Your search keyword '"Pearlman, Tsilke"' showing total 8 results
Start Over Author "Pearlman, Tsilke"
8 results on '"Pearlman, Tsilke"'

3. Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals

Author

Buchwald, Dedra, Pearlman, Tsilke, Umali, Jovine, Schmaling, Karen, and Katon, Wayne

Subjects
Chronic fatigue syndrome -- Physiological aspects, Health, Health care industry
Abstract

BACKGROUND: Chronic fatigue syndrome (CFS) is a condition that may be associated with substantial disability. The Medical Outcomes Study Short-Form General Health Survey (SF-36) is an instrument that has been widely used in outpatient populations to determine functional status. Our objectives were to describe the usefulness of the SF-36 in CFS patients and to determine if subscale scores could distinguish patients with CFS from subjects with unexplained chronic fatigue (CF), major depression (MD), or acute infectious mononucleosis (AIM), and from healthy control subjects (HC). An additional goal was to ascertain if subscale scores correlated with the signs and symptoms of CFS or the presence of psychiatric disorders and fibromyalgia. DESIGN: Prospectively collected case series. SETTING: Patients with CFS and CF were seen in a university-based referral clinic and had undergone a complete medical and psychiatric evaluation. Other study subjects were recruited from the community to participate in research studies. PARTICIPANTS: The study included 185 patients with CFS, 246 with CF, 111 with AIM, and a with MD. There were 99 HC subjects. MEASURES: The SF-36 and a structured psychiatric interview were used. The SF-36 contains 8 subscales. physical, emotional, social, and role functioning, body pain, mental health, vitality, and general health - and a structured psychiatric interview. RESULTS: Performance characteristics (internal reliability coefficients, convergent validity) of the SF-36 were excellent. A strikingly consistent pattern was found for the physical functioning, role functioning, social functioning, general health, and body pain subscales, with the lowest scores in CFS patients, intermediate scores in AIM patients, and the highest scores in the HC subjects. The CFS patients had significantly lower scores than patients with CF alone on the physical functioning (P [less than or equal to] 0.01), role functioning (P [less than or equal to] 0.01), and body pain (P [less than or equal to] 0.001). subscales. The emotional functioning and mental health scores were worst among those with MD. The presence of fibromyalgia, being unemployed, and increasing fatigue severity all were associated with additional functional limitations across multiple functional domains, with increasing fatigue appearing to have the greatest effect. CONCLUSIONS: The SF-36 is useful in assessing functional status in patients with fatiguing illnesses. Patients with CFS and CF have marked impairment of their functional status. The severity and pattern of impairment as documented by the SF-36 distinguishes patients with CFS and CF from those with MD and AIM, and from HC, but does not discriminate between CF and CFS. Am J Med. 1996;171:364-370.

Published
1996

4. HIV transmission: women's risk from bisexual men

Author

Wood, Robert W., Krueger, Leigh E., Pearlman, Tsilke C., and Goldbaum, Gary

Subjects
HIV infection -- Risk factors, Gay men -- Sexual behavior, Sexual orientation -- Health aspects, Bisexuality -- Health aspects, Government, Health care industry
Abstract

The purpose of this study was to characteristic the risk of human immunodeficiency virus (HIV) infection for men who have sex with men and to identify the risk such men pose to their female sex partners. The subjects were 5480 men who were tested for HIV between January 1987 and December 1991 and who reported having had sex with a man since 1977. Men who identified themselves as bisexual or straight were more likely to use injection drugs, had a substantial HIV seroprevalence, and reported many more female partners than men who identified themselves as gay. Men who identify themselves as bisexual pose the greatest risk to their female partners. (Am J Public Health 1993;83:1757-1759), Women who have sex with bisexual men may have an increased risk of HIV infection. A total of 5,480 men were surveyed regarding their sexual orientation and sexual activity in the previous 12 months. They were also tested for HIV infection. Seventy-seven percent identified as gay and had had almost no sex with women in the past year. These men also had the highest rate of HIV infection (27%). A total of 457 identified as straight, with an HIV infection rate of 8%. Infected men from these two groups had a combined total of 64 female partners. The HIV infection rate for the 711 who identified as bisexual was 12%. The bisexual men who were HIV-infected reported a total of 116 female partners and exposed the most women to HIV infection in the previous year. More research is needed to determine the risk of HIV infection among men who have sex with other men but do not call themselves gay. Research is also needed on the risk for men who are injection drug users and have sex with other men.

Published
1993

8. Postinfectious Chronic Fatigue: A Distinct Syndrome?

Author

Buchwald, Dedra, Umali, Jovine, Pearlman, Tsilke, Kith, Phalla, Ashley, Rhoda, and Wener, Mark

Abstract

Chronic fatigue syndrome (CPS) is often preceded by a viral illness and has recurrent “flulike” symptoms. We compared demographic, clinical, and laboratory features (markers of inflammation and viral infection) among 717 patients with chronic fatigue (CF) with and without a self-reported postinfectious onset to identify associated clinical and biologic findings and to examine the subset of patients with CFS. Only subjective fever, chills, sore throat, lymphadenopathy, poorer functional status, and attribution of illness to a physical condition were significantly associated with a postinfectious onset. The features of patients with CPS were virtually identical to those of the broader category of patients with CF. We conclude that a postinfectious onset was not associated with a pattern of abnormalities across multiple psychosocial and biologic parameters. [ABSTRACT FROM PUBLISHER]

Published
1996

Catalog

Books, media, physical & digital resources
See catalog results