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Your search keyword '"Peacock, Janet L."' showing total 697 results
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697 results on '"Peacock, Janet L."'

1. Do small effects matter more in vulnerable populations? an investigation using Environmental influences on Child Health Outcomes (ECHO) cohorts

Author

Peacock, Janet L., Coto, Susana Diaz, Rees, Judy R., Sauzet, Odile, Jensen, Elizabeth T., Fichorova, Raina, Dunlop, Anne L., Paneth, Nigel, Padula, Amy, Woodruff, Tracey, Morello-Frosch, Rachel, Trowbridge, Jessica, Goin, Dana, Maldonado, Luis E., Niu, Zhongzheng, Ghassabian, Akhgar, Transande, Leonardo, Ferrara, Assiamira, Croen, Lisa A., Alexeeff, Stacey, Breton, Carrie, Litonjua, Augusto, O’Connor, Thomas G., Lyall, Kristen, Volk, Heather, Alshawabkeh, Akram, Manjourides, Justin, Camargo, Jr, Carlos A., Dabelea, Dana, Hockett, Christine W., Bendixsen, Casper G., Hertz-Picciotto, Irva, Schmidt, Rebecca J., Hipwell, Alison E., Keenan, Kate, Karr, Catherine, LeWinn, Kaja Z., Lester, Barry, Camerota, Marie, Ganiban, Jody, McEvoy, Cynthia, Elliott, Michael R., Sathyanarayana, Sheela, Ji, Nan, Braun, Joseph M., and Karagas, Margaret R.

Published
2024
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4. A multicenter randomized controlled trial indicates that paclitaxel-coated balloons provide no benefit for arteriovenous fistulas

Author

Karunanithy, Narayan, Robinson, Emily J., Ahmad, Farhan, Burton, James O., Calder, Francis, Coles, Simon, Das, Neelanjan, Dorling, Anthony, Forman, Colin, Jaffer, Ounali, Lawman, Sarah, Lakshminarayan, Raghuram, Lewlellyn, Rhys, Peacock, Janet L., Ramnarine, Raymond, Mesa, Irene Rebollo, Shaikh, Shoaib, Simpson, James, Steiner, Kate, Suckling, Rebecca, Szabo, Laszlo, Turner, Douglas, Wadoodi, Ashar, Wang, Yanzhong, Weir, Graeme, Wilkins, C. Jason, Gardner, Leanne M., and Robson, Michael G.

Published
2021
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6. Selective dorsal rhizotomy in ambulant children with cerebral palsy: an observational cohort study

Author

Summers, Jennifer, Coker, Bola, Eddy, Saskia, Elstad, Maria, Bunce, Catey, Bourmpaki, Elli, Pennington, Mark, Aquilina, Kristian, Cawker, Stephanie, Edwards, Richard, Goodden, John, Hawes, Sally, McCune, Kate, Pettorini, Benedetta, Smith, Jennifer, Sneade, Christine, Vloeberghs, Michael, Patrick, Hannah, Powell, Helen, Verity, Christopher, and Peacock, Janet L

Published
2019
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7. Patient-Reported Outcome Measures Following Hyperbaric Oxygen Therapy for Radiation Cystitis: Early Results From the Multicenter Registry for Hyperbaric Oxygen Therapy.

Author

Moses, Rachel A., Hunter, Alexandra E., Brandes, Eileen R., Ziyin Zhang, Rees, Judy R., Peacock, Janet L., Bihrle III, William, Sethuraman, Kinjal, Weaver, Lindell K., and Buckey Jr, Jay C.

Subjects
HYPERBARIC oxygenation, RADIOTHERAPY, CYSTITIS, PROSTATE cancer
Abstract

Purpose: Our purpose was to determine changes in patient-reported hematuria and urinary symptoms after hyperbaric oxygen (HBO2) treatment for radiation cystitis (RC). Materials and Methods: We analyzed prospectively collected data from the Multicenter Registry for Hyperbaric Oxygen Therapy Consortium accumulated within a week of beginning and ending HBO2. Measures included the modified Radiation Therapy Oncology Group (RTOG) Hematuria Scale, Urinary Distress Inventory Short Form, and EuroQol Five Dimension Five Level instrument. RTOG hematuria and Urinary Distress Inventory Short Form scores were compared using the sign test. Logistic regression was used to evaluate characteristics associated with hematuria improvement. Results: A total of 470 registry patients had RC. The median age, number of HBO2 sessions, and years after radiation were 73 (IQR 12) years, 39 (IQR 10) sessions, and 5 (IQR 8) years, respectively. Eighty-four percent of patients (393/470) had prostate cancer--related radiation. EuroQol Five Dimension Five Level scores improved from 0.83 (IQR 0.14) to 0.85 (IQR 0.22; P < .001. Three hundred seventy patients had complete RTOG hematuria scores that improved from 2 (IQR 2) to 0 (IQR 2; P < .001. Two hundred forty-six patients had complete Urinary Distress Inventory Short Form ratings that decreased from 33.3 (IQR 44) to 22.2 (IQR 33; P < .001). Regression analysis of those with visible hematuria before HBO2 showed lower improvement odds associated with higher HBO2 hematuria scores (odds ratio [OR] 0.44, 95% CI 0.26-0.73; P < .01), a smoking history (OR 0.44, 95% CI 0.21-0.92; P [ .03), or a nonprostate cancer history (OR 0.32, 95% CI 0.10-0.99; P [ .05). Conclusions: HBO2 for RC improved reported hematuria, urinary function, and quality of life. Higher baseline hematuria scores, smoking, and nonprostate cancer history were associated with lower odds of hematuria improvement. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Development of an International, Multicenter, Hyperbaric Oxygen Treatment Registry and Research Consortium: Protocol for Outcome Data Collection and Analysis

Author

Harlan, Nicole P, Ptak, Judy A, Rees, Judy R, Cowan, Devin R, Fellows, Abigail M, Kertis, Judith A, Hannigan, Pamela M, Peacock, Janet L, and Buckey, Jay C

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundHyperbaric oxygen (HBO2)—oxygen at pressures higher than atmospheric—is approved for 14 indications by the Undersea and Hyperbaric Medical Society. HBO2’s main effect is to increase oxygen content in plasma and body tissues, which can counteract hypoxia or ischemia. Laboratory studies show that HBO2 has effects beyond relieving hypoxia (eg, promoting angiogenesis in irradiated tissue, anti-inflammatory effects, radiosensitization of tumors, hypoxia preconditioning, and fungal growth inhibition) and has potential to treat conditions such as inflammatory bowel disease and pyoderma gangrenosum. Lack of consistently collected outcome data on a large cohort of individuals receiving HBO2 therapy limits its use for both established and new indications. A course of therapy often involves 30-40 visits to a hyperbaric chamber, so the number of patients seen at any given center is constrained by chamber capacity. As a result, published HBO2 outcome data tend to be from small case series because few patients with a particular condition are treated at a given center. To solve this problem, a registry that collects and pools data systematically from multiple institutions has been established. ObjectiveThe aim of this study is to collect consistent outcome data across multiple hyperbaric centers to assess treatment effectiveness and establish a research consortium. MethodsA consortium of hyperbaric centers who have agreed to collect consistent outcome data on all patients seen has been assembled. Data are collected at each participating center using Research Electronic Data Capture (REDCap), a web-based, data collection system used frequently for research. Standard outcome measures have been defined for each condition, which are programmed into the REDCap data collection templates. Governance is through a consortium agreement that defines data security, data sharing, publications, liability, and other issues. Centers obtain Institutional Review Board (IRB) and ethics approval to participate, either from their own institutions or by relying on the IRB at the coordinating center at Dartmouth College. Dissemination will occur through a yearly report and by publications based on the data in the registry. ResultsEarly results from some common indications show significant pretreatment to posttreatment changes. Additional indications and outcome measures are being added using the procedures outlined in the consortium agreement. ConclusionsThe registry collects consistent outcome information for a therapy that needs further study and a stronger evidence base. It also overcomes the challenge of collecting data from an adequate number of patients for both established and emerging indications by combining data collection from multiple centers. The data entry requirements should be within the capabilities of existing staff at any given hyperbaric center. By using REDCap, the registry can be expanded to include detailed information on particular indications and long-term follow-up on selected patients without significantly increasing the basic data entry requirements. Through the registry, a network of enrolled hyperbaric centers has been established that provides the basis for a clinical trial network. International Registered Report Identifier (IRRID)DERR1-10.2196/18857

Published
2020
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49. Cancer Epidemiology in the Northeastern United States (2013-2017)

Author

Rees, Judy R, primary, Weiss, Julie E, additional, Gunn, Christine M, additional, Carlos, Heather A, additional, Dragnev, Nathalie C, additional, Supattapone, Emma Y, additional, Tosteson, Anna N.A., additional, Kraft, Sally A, additional, Vahdat, Linda T, additional, and Peacock, Janet L, additional

Published
2023
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