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Byline: S. Kumar, Nikhil. Jain, Smita. Prakash, Mridula. Pawar Sir, Several drugs used in anaesthesia and intensive care may cause blockade of the central cholinergic neurotransmission. We report a suspected [...]

Byline: Smita. Prakash, Pooja. Virmani, Pramod. Gupta, Mridula. Pawar Sir, Percutaneous nephrolithotomy (PCNL) is used commonly for the treatment of large renal and upper ureteric calculi. We report a 30-year-old [...]

Byline: Tanvir. Samra, Mridula. Pawar, Jasvinder. Kaur Blast injuries are rare, but life-threatening medical emergencies. We report the clinical presentation and management of four bomb blast victims admitted in Intensive [...]

Byline: Madhu. Dayal, Smita. Prakash, Pradeep. Verma, Mridula. Pawar The spectrum of presentation of a victim of neurotoxic snake bite can range from mild ptosis to complete paralysis and ophthalmoplegia. [...]

Byline: Tanvir. Samra, Mridula. Pawar Objectives: To evaluate the efficacy of chemoprophylactic dose of oseltamivir in preventing H1N1 by comparing the rates of acute respiratory illness and H1N1 positivity of [...]

Byline: Rakesh. Garg, Ajay. Goila, Mridula. Pawar Sir, The episodes of haemodynamic disturbances may lead to activation of various protective physiological reflexes. Clinical occurrences of Bezold-Jarisch reflex (BJR) is not [...]

Byline: Rakesh. Garg, Sujata. Sharma, Seema. Rathee, Mridula. Pawar Sir, Large thyroid masses are a nightmare for the anaesthesiologist not only because of thyroid endocrinal abnormality but also because of [...]

Byline: Nishkarsh. Gupta, Sarbjot. Kaur, Ajay. Goila, Mridula. Pawar We describe for the first time, the perioperative care of a patient with a rare combination of Eisenmenger syndrome with ß-thalassemia [...]

Byline: Tanvir. Samra, Mridula. Pawar, Amlendu. Yadav H1N1 subtype of influenza A virus has clinical presentation ranging from mild flu like illness to severe lung injury and acute respiratory distress [...]

Byline: Tanvir. Samra, Amlendu. Yadav, Neerja. Banerjee, Mridula. Pawar, Desh. Deepak A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which [...]

Byline: Nishkarsh. Gupta, Pradeep. Karunagaran, Mridula. Pawar Sir, A loose tooth or teeth always pose a problem for the anaesthesiologist during laryngoscopy and endotracheal intubation. This problem is aggravated if [...]

Byline: Ajay. Goila, Mridula. Pawar Physicians, health care workers, members of the clergy, and laypeople throughout the world have accepted fully that a person is dead when his or her [...]

Byline: Mohandeep. Kaur, Mridula. Pawar, Jasvinder. Kohli, Shailendra. Mishra This prospective study was designed to have an insight into critical events occurring in the 13-bedded multidisciplinary intensive care unit (ICU) [...]

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Background: Etomidate injection is often associated with myoclonus. Etomidate injection technique influences the incidence of myoclonus. This study was designed to clarify which of the two injection techniques--slow injection or priming with etomidate--is more effective in reducing myoclonus. Methods: This prospective randomized controlled study was conducted on 189 surgical patients allocated to three study groups. Control group (Group C, n = 63) received 0.3 mg/kg etomidate (induction dose) over 20 s. Priming group (Group P, n = 63) received pretreatment with 0.03 mg/kg etomidate, followed after 1 min by an etomidate induction dose over 20 s. Slow injection group (Group S, n = 63) received etomidate (2 mg/ml) induction dose over 2 min. The patients were observed for occurrence and severity of myoclonus for 3 min from the start of injection of the induction dose. Results: The incidence of myoclonus in Group P (38/63 [60.3%], 95% CI: 48.0-71.5) was significantly lower than in Group C (53/63 [84.1%], 95% CI: 72.9-91.3, P = 0.003) and Group S (49/63 [77.8%], 95% CI: 66.0-86.4, P = 0.034). Myoclonus of moderate or severe grade occurred in significantly more patients in Group C (68.3%) than in Group P (36.5%, P < 0.001) and Group S (50.8%, P = 0.046), but the difference between Groups P and S was not significant (P = 0.106). Conclusions: Priming is more effective than slow injection in reducing the incidence of myoclonus, but their effects on the severity of myoclonus are comparable. [ABSTRACT FROM AUTHOR]