40 results on '"Pavlović, Katarina"'
Search Results
2. Impact of the Knowledge and Innovation Culture on Non-financial Performance of Serbian SMEs
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Pavlović, Katarina, Depalov, Vesna Rašković, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Karabegović, Isak, editor, Kovačević, Ahmed, editor, and Mandžuka, Sadko, editor
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- 2022
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3. Bis(benzimidazol‐2‐yl)amine‐Based DPP‐4 Inhibitors Potentially Suitable for Combating Diabetes and Associated Nervous System Alterations.
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Tomović Pavlović, Katarina, Ilić, Budimir S., Leitzbach, Luisa, Anichina, Kameliya K., Yancheva, Denitsa, Živković, Aleksandra, Mavrova, Anelia Ts, Stark, Holger, and Šmelcerović, Andrija
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- 2024
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4. Effects of Digital Citizenship and Digital Transformation Enablers on Innovativeness and Problem-Solving Capabilities.
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Slavković, Marko, Pavlović, Katarina, Depalov, Vesna Rašković, Vučenović, Tamara, and Bugarčić, Marijana
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DIGITAL transformation ,DIGITAL technology ,PROBLEM solving ,TECHNOLOGICAL innovations ,CITIZENSHIP ,INFORMATION resources management - Abstract
Featured Application: The study's findings indicate the positive outcomes of digital citizenship, while also exposing domains that fail to enhance innovativeness and problem-solving capabilities, with digital transformation enablers serving as a mediating factor. Doing business in the age of information abundance indicates the importance of developing information management skills, enabling the individuals to be more productive but also more flexible to changes. In literature, innovation, as a driver of a firm's performance, has been highlighted, while problem-solving capabilities are considered one of the key assumptions for the implementation of digital transformation strategy. The purpose of the study is to investigate the impact of digital citizenship and digital transformation enablers on innovation and problem-solving capabilities. The data collection procedure commenced by selecting a random sample of private companies from various industries A survey was carried out, and a total sample of 247 valid questionnaires were collected. The PLS-SEM method was used to test the relationships in the proposed model. The study found that some elements of digital citizenship are positively associated with digital transformation enablers. The results of the study confirmed that technology-based digital transformation enablers positively contribute to innovation and problem-solving capabilities. Also, technological facets of digital transformation enablers realize a mediating role in the relationship between digital citizenship and innovation, as well as with problem-solving capabilities. [ABSTRACT FROM AUTHOR]
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- 2024
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5. KNOWLEDGE TRANSFER PROCESS IN VETERINARY INSTITUTES: EXPLORATION OF ENHANCING FACTORS.
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Pavlović, Katarina, Depalov, Vesna Rašković, Dukić, Nadežda, and Ivković, Ivan
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KNOWLEDGE transfer ,CORPORATE culture ,WORK experience (Employment) ,INTRINSIC motivation ,EMPIRICAL research - Abstract
In the past three decades knowledge transfer process has been recognized as one of the main drivers of a company’s success through raising its learning and decisionmaking capabilities, and contributing to innovation and growth. For this reason, a very important part of organisational activities is enhancing the knowledge transfer process. In this empirical study, five factors were chosen and tested, on all 12 veterinary institutes in Serbia, to show if these contribute to the process, and also to show if there are any differences among the two types of institutes on an individual, organisational and technological level. Three hypotheses were tested. Two, related to the differences among institutes and factors, were proved, and the one, related to the association of individual level and number of years of work experience and professional rank, was rejected. This study is one of the first to cover this area of interest and also points to the path for future research. [ABSTRACT FROM AUTHOR]
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- 2024
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6. ANALYSIS OF SPECIFIC IMPROVEMENT AREAS IN START-UP ACTIVITY IN SERBIA.
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Depalov, Vesna Rašković and Pavlović, Katarina
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INTELLECTUAL property ,NEW business enterprises ,DIGITAL technology - Abstract
Raising the level of knowledge is essential for startups pursuing growth and aiming at keeping their innovation potential high. Since innovation activity has been the driving force of economies worldwide, governments tend to focus on providing knowledge through various support programs in order to accelerate innovations. The aim of the study presented in this paper was to find out what types of knowledge and what factors contribute positively to this process. For this purpose, methodology used was based on interviews and questionnaire. 82 participants were selected for the study. Four hypotheses were tested and proven. One, related to the needed team knowledge, and three, related to digitalisation level, intellectual property rights protection, and gender influencing time-toprofit. The results of the study obtained are presented and discussed in the paper and these findings may be used as a guidance for further support to the Serbian innovation ecosystem. [ABSTRACT FROM AUTHOR]
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- 2023
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7. PREDICTIVE ROLE OF KNOWLEDGE CULTURE AND INNOVATION CULTURE ON NON-FINANCIAL PERFORMANCE INDICATORS.
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Pavlović, Katarina, Rašković-Depalov, Vesna, and Milovanović, Mirjana
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CORPORATE culture ,INDEPENDENT variables ,BUSINESS size ,DEPENDENT variables ,SMALL business - Abstract
The aim of the research presented in this study was testing the correlation of knowledge and innovation culture and non-financial performance indicators (NFPIs), the predictive role of independent variables knowledge and innovation culture in NFPIs and differences between dependent and independent variables between micro, small and medium size companies. The study included 124 Serbian MSMEs, that voluntarily responded to 40 questions, presenting the research instrument. Statistical data analysis showed that a significant correlation exists between dependent and independent variables, that knowledge and innovation culture predict NFPIs with 33.4% and that there are differences in innovation culture and NFPIs, but not knowledge culture between companies grouped according to size. The conclusion of the study is that innovation and knowledge culture are of high importance for MSMEs, due to their predictive role in NFPIs, which are most often used, according to literature findings, for the assessment of their long-term success and sustainability. This study also revealed that the highest level of innovation culture and NFPIs is in micro companies in Serbia. [ABSTRACT FROM AUTHOR]
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- 2023
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8. New combination of methods for isolation and purification of pertussis toxin from the Bordetella pertussis culture
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Pavlović Katarina B. and Božanić Vojislav N.
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Bordetella pertussis ,pertussis toxin ,accelular pertussis vaccine ,isolation and purification of pertussis toxin ,Chemical technology ,TP1-1185 - Abstract
In this paper a method for isolation and purification of the pertussis toxin from the cell culture of Bordetella pertussis was presented. Pertussis toxin production was enhanced with the optimization of the microbiological media and cultivation time. Relatively high degree of purification of 80,39% and yield of 56% was resulted by the unique combination of the protein isolation and purification methods. Using immunoelectrophoresis and high performance liquid chromatography, in comparison with pertussis toxin WHO standard, it was verified that the protein isolated is indeed pertussis toxin. The conclusion of this paper is that this unique combination of the different techniques along with the specific modifications implemented would give good results in pertussis toxin isolation and purification on laboratory level, while scaling up of this methodology could be the objective of future research. It can also be concluded that, no matter what literature data say and what opinions other authors have, all methods and working conditions should be examined and optimized for the reason of the specificity of the autochthonous species as well as the dynamic changes in this field.
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- 2011
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9. Laboratory testing of hemolytic properties of materials that come in contact with blood: Comparative application testing method’s two variants according to the standard ASTM F756 in accordance with ISO 10993-4
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Pavlović Katarina B., Božanić Vojislav N., Stanojević Jasna V., Milićević Vesna K., and Ilić Bojan J.
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Hemolytic Properties of Materials ,Biology laboratory tests ,ASTM F756 ,ISO 10993-4 ,SRPS ISO 5725-1 ,Cost-effectiveness ,Chemical technology ,TP1-1185 - Abstract
The presence of hemolytic material in contact with blood may produce increased levels of blood cell lysis and increased levels of plasma hemoglobin. This may induce toxic effects or other effects which may stress the kidneys or other organs. In this paper two variants of in vitro method and obtained results’ comparison were presented for testing of hemolytic properties of six raw materials (Polipropylene Moplen EP 540 P, Policarbonate colorless 164 R-112, Policarbonate brown 164 R-51918, Polietylene NG 3026 K, Polietylene NG - Purell GB 7250, Polietylene VG - Hiplex 5502) for medical device manufacturing and one raw material (Polietylen NG granulate) used for infusion solutions’s plastic bottles manufacturing. One of method’s variants relies on raw material direct contact with swine blood and the other on extract of the material contact with swine blood. Both method’s variants imply reading of the absorbance of the supernatant after tubes were incubated and centrifuged. According to values obtained and using the standard curve free hemoglobin concentration is determined and based on this percentage hemolysis of raw material. Positive and negative controls were used in both variants where water for injection (WFI) was used as positive control in which partial or complete hemolysis of erythrocytes occurs due to osmotic shock and phosphate buffer saline was used as negative control with no hemolytic property. In this paper comparison of results obtained by both method’s variants for testing of seven raw materials was presented, while these conclusions can not be used neither for all materials, nor for all applications without preliminary testing using both variants and then choosing more sensitive and more reliable one. It was shown and stated in the paper as well that incubation time being 3, 15 or 24 h, had no impact on the variant’s with direct contact sensitivity. This comparative approach was used for drawing conclusions in terms of suitability for application of one or the other method’s variant, as well as for defining relevant incubation time and finally for choosing more sensitive and more reliable variant for assessment of hemolytic properties of raw materials. Variant with direct contact was chosen from the aspect of less complexity regarding necessary laboratory equipment which makes it economically more favorable and fit for the purpose.
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- 2010
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10. Importance of pharmaceutical laboratory compliance with international standard requirements in respect of raising their competitiveness
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Božanić Vojislav N., Pavlović Katarina B., Milićević Vesna K., and Ilić Bojan J.
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pharmaceutical industry laboratory ,accreditation ,standard ISO/IEC 17025 ,CGMP ,competitiveness ,Chemical technology ,TP1-1185 - Abstract
Current Good Manufacturing Practice (cGMP) being a legal regulation in developed countries will become a legal regulation in Republic of Serbia starting with March 2010. In this paper comparative analysis between requirements of standard ISO/IEC 17025 and requirements of cEU GMP is shown. Considering the fact that in Republic of Serbia no pharmaceutical industry laboratory has been accredited according to requirements of ISO/IEC 17025, while keeping in mind that more than 90% of these laboratories have not fulfilled cEU GMP requirements, this paper aimed at pointing to the possibility of fulfilling both of mentioned requirements at the same time, which would open the way to different types of interlaboratory cooperation for pharmaceutical quality control laboratories and contribute to improving competitiveness of pharmaceutical companies. Accreditation, especially in the case of pharmaceutical quality control laboratories, is important because it guaranties the level of organizational and technical competency. It could easily be said that accreditation is becoming a must in quality control of products in order for the organization to be able to gain a leading role in the global market. Both accreditation and cGMP show the organization's commitment to having products of highest quality level. Considering the above mentioned facts, it is of greatest advantage for pharmaceutical quality control laboratories to fulfill both requirements of ISO/IEC 17025 and cGMP and reach total compliance. The aim of doing this lies in an easier acceptance of pharmaceutical products in different markets, overcoming technical barriers and affirmation of quality as key factor in reaching competitiveness, while keeping in mind the importance of strategic and competitive positioning in the global market.
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- 2009
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11. Impact of Digital Capabilities on Digital Transformation: The Mediating Role of Digital Citizenship.
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Slavković, Marko, Pavlović, Katarina, Mamula Nikolić, Tatjana, Vučenović, Tamara, and Bugarčić, Marijana
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DIGITAL transformation ,DIGITAL technology ,INFORMATION technology security ,INFORMATION literacy ,SECURITY management - Abstract
The imperative of changes associated with digital transformation gave impetus to this study, which aims to examine the impact of digital capabilities and digital citizenship on digital transformation, as well as to identify the role of digital citizenship in the relationship between digital capabilities and digital transformation. Digital transformation is observed via change management and risk management, and two facets of digital citizenship are examined: information and data literacy and information security management. A survey was carried out, and respondents were managers employed in companies from various industries in Serbia. Considering the total sample of 224 valid questionnaires the PLS-SEM method was used to test the relationships in the proposed model. Results suggest that digital capabilities have a significant positive impact on change management, information and data literacy, and information security management. Results also confirm that digital citizenship mediates the relationship between digital capabilities and both change management and risk management. [ABSTRACT FROM AUTHOR]
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- 2023
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12. KRETANJE BRUTO DOMAĆEG PROIZVODA BOSNE I HERCEGOVINE POD UTICAJEM SVJETSKE FINANSIJSKE KRIZE
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Pavlović, Katarina, primary and Božić, Rade, primary
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- 2022
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13. Removal of cadmium(II) ions using Saccharomyces cerevisiae and Leuconostoc mesenteroides immobilized in silica materials by two processing methods
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Stanojević-Nikolić, Slobodanka, primary, Pavlović, Katarina V., additional, Nikolić, Milan P., additional, Srdić, Vladimir V., additional, and Šćiban, Marina, additional
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- 2022
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14. Differences between managing board in joint stock company and limited liability company
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Pavlović, Katarina, Miladin, Petar, Jakšić, Tomislav, and Bilić, Antun
- Abstract
Ovaj rad iz područja prava društava, bavi se jednim od organa u dva najvažnija oblika trgovačkih društava danas na tržištu, upravom u dioničkom društvu i upravom u društvu s ograničenom odgovornošću. Funkcioniranje ovih društva, koja su pravna osoba za sebe različita od svojih članova, nezamislivo je bez organa kao što je uprava. Teorijski dio rada pisan je prateći odredbe Zakona o trgovačkim društvima i teorijske teze na temu uprave s naglaskom na razlike između uprave u ta dva oblika društava. Najprije se daje kratki uvid u najvažnija obilježja dioničkog društva kao ultimativnog oblika društva kapitala. Nadalje, slijede izlaganja o položaju uprave u društvu, mogućim članovima uprave te uvjetima koje trebaju zadovoljiti da bi postali članovima uprave. Nadalje, prelazi se na ovlasti uprave u društvu, prestanak članstva u upravi te dužnoj pozornosti i odgovornostima članova uprave. U drugom dijelu rada se na isti način obrađuje društvo s ograničenom odgovornošću. Povlačenjem paralela s dioničkim društvom, budući da su uz uočene razlike mnoge stvari podjednako uređene, iznose se zaključci rada. Navode se manje razlike koje se tiču trajanja mandata člana uprave, izbora predsjednika uprave među članovima i druge. Za kraj se nastoji dati odgovor na pitanje s kojim započinje rad: pravni obliku u kojem na tržištu najbolje može djelovati član nekog budućeg društva, stoga se nudi kratak odgovor iz perspektive uprave pojedinog društva.
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- 2021
15. Synthesis and Characterization of Silica Core/Multilayered Cobalt Ferrite-Silica Shell Particles for Lipase Immobilization
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Nikolić, Milan P., primary, Pavlović, Katarina V., additional, Stanojević-Nikolić, Slobodanka, additional, Maričić, Aleksa, additional, and Srdić, Vladimir V., additional
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- 2021
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16. Predicting the type of physical activity from tri-axial smartphone accelerometer data
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Pavlović, Katarina, primary
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- 2021
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17. TRENDS IN THE DEVELOPMENT OF COMPETENCIES OF PROJECT MANAGERS IN THE PROCESS OF DIGITALIZATION OF SOCIETY AND INDUSTRY 4.0
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Ostojić, Bojana, primary, Pavlović, Katarina, additional, and Petrušić, Irena, additional
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- 2020
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18. KOMPETENCIJE UČITELJA ZA PLANIRANJE I REALIZACIJU NASTAVE SOLFEGGIA
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Pavlović, Katarina
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solfeggio, glazbeno obrazovanje, kompetencije učitelja, učitelj solfeggia, nastavne metode, metodika nastave solfeggia - Abstract
Cilj ovoga rada je prikazati cjelokupan kompetencijski profil učitelja solfeggia. On podrazumijeva znanja, vještine i sposobnosti unutar tri dimenzije: pedagoške, didaktičke i metodičke, prilikom čega svaka ravnopravno sudjeluje u ostvarivanju odgojno-obrazovnog procesa. U prvom dijelu rada su iznesene opće kompetencije koje su potrebne svakom učitelju, neovisno o području njegove specijalizacije, prilikom ostvarivanja odgojne i obrazovne komponente nastavnoga procesa. Odgojna komponenta bazira se na činjenici da učenici uče po modelu, a obrazovna na suvremenom pristupu implementacije kurikuluma u nastavni proces, koji stavlja fokus na učenikove potrebe umjesto nastavnog sadržaja. Kako bi se nastavni sadržaj mogao prilagoditi učeniku, potrebno je da učitelj ima razvijene stručne kompetencije koje se odnose na područje njegove specijalizacije. Stoga će u drugom dijelu biti detaljno raščlanjene metodičke kompetencije unutar planiranja i realizacije nastave solfeggia.
- Published
- 2020
19. THE GLOBALIZATION OF FINANCIAL MARKETS AND ITS IMPACT ON CHANGE OF THE PORTFOLIO MANAGEMENT STRATEGY IN COMMERCIAL BANKS
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Bojagić, Dražen; Standard računovodstvene usluge d.o.o. Bijeljina, Bijeljina, Republika Srpska, Bosna i Hercegovina, Pavlović, Katarina; Student osnovnih studija Fakulteta poslovne ekonomije, Bijeljina, Republika Srpska, BIH, Bojagić, Dražen; Standard računovodstvene usluge d.o.o. Bijeljina, Bijeljina, Republika Srpska, Bosna i Hercegovina, and Pavlović, Katarina; Student osnovnih studija Fakulteta poslovne ekonomije, Bijeljina, Republika Srpska, BIH
- Abstract
The traditional concept of banking was based on the collection of monetary funds from natural and legal persons, and their placement towards the persons that required these monetary funds, in order to make a profit on the difference between the active and the passive interest rate. In modern banking, banks under the influence of globalization characterized by a high degree of interbank competition, come out of the traditional banking concept and direct part of their financial potential into the building of their investment portfolios. By choosing and applying the right policy for managing the investment portfolio the banks generate profit, but they shouldn’t ignore the level of exposure to the risk associated with operations with financial instruments. The aim of this research is to show that commercial banks, through the change in management policy, respond to the challenges of the modern global financial market, with particular reference to the domicile banking. The research will include traditional banking, the development of financial markets, globalization characteristics, investment banking and the risks banks are facing with, as well as the policy of managing with assets and risks of banks in Bosnia and Herzegovina in general., Tradicionalni koncept bankarstva podrazumijevao je prikupljanje novčanih sredstava od suficitarnih subjekata i njihov plasman ka deficitarnim subjektima u cilju ostvarivanja zarade na razlici između aktivne i pasivne kamatne stope. U savremenom bankarskom poslovanju, banke pod uticajem globalizacije koju karakteriše visok stepen međubankarske konkurencije izlaze iz okvira tradicionalnih bankarskih poslova i dio svog finansijskog potencijala usmjeravaju u formiranje investicionog portfolija. Izborom i primjenom prave politike upravljanja investicionim portfoliom banke ostvaruju dobit, ali ne trebaju zanemariti prisutnu izloženost riziku koji prati poslovanje sa finansijskim instrumentima. Cilj ovog istraživanja je da pokaže kako poslovne banke kroz promjenu politike upravljanja odgovaraju na izazove savremenog globalnog finansijskog tržišta, sa posebnim osvrtom na domicilno bankarstvo. Istraživanje će obuhvatiti tradicionalno bankarstvo, razvoj finansijskih tržišta, karakteristike globalizacije, investiciono poslovanje banaka i rizik sa kojima se banke suočavaju, te politiku upravljanja aktivom i rizicima banaka u Bosni i Hercegovini.
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- 2020
20. L'évolution des approches à la traduction: analyse traductologique des plusieurs traductions françaises du livre 4 de l'Enéide
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Pavlović, Katarina
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traductologie, littérature antique, Enéide, réception, grand public - Abstract
Ce mémoire de Master, qui traite un thème traductologique, est composé de quatre parties. Au début on trouve le cadre théorique qui définit l'objet d'étude et les principaux déterminants de la traductologie en tant que discipline scientifique. La partie centrale est consacrée à la traduction de deux articles scientifiques ayant pour thème commun la réception contemporaine des traductions de la littérature antique. La troisième partie donne une courte présentation de l'évolution des approches à la traduction, et l'analyse des trois traductions françaises du livre 4 de l'Enéide. Dans la partie finale se trouve un résumé des conclusions issues de l'analyse, du point de vue du public cible.
- Published
- 2019
21. Local guidelines for drug treatment of patients with COVID-19
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Janković, Slobodan, primary, Pavlović, Katarina, additional, Vukićević, Vladimir, additional, Gavrilović, Jagoda, additional, Folić, Marko, additional, Čanović, Predrag, additional, Marjanović, Ružica, additional, Mojsilović, Slavica, additional, Stevanović, Nebojša, additional, and Rosić, Nikola, additional
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- 2020
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22. Management Education and Sustainable Development Projects
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Ostojić, Bojana, primary, Berić, Ivana, additional, Pavlović, Katarina, additional, and Pećić, Milutin, additional
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- 2020
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23. RECONCILIATION IN SOUTH AFRICA AS A(N) (IM)POSSIBLE MODEL FOR THE POST-YUGOSLAV AREA.
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Vučinić, Dejan, Milenković, Miloš, and Pavlović, Katarina
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RECONCILIATION ,APARTHEID ,TRUTH commissions ,SOCIAL processes - Abstract
Copyright of TEME: Casopis za Društvene Nauke is the property of TEME: Casopis za Drustvene Nauke and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
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24. Developing an athletic club´s graphic profile: The production of logo and visualidentity for a Swedish powerlifting club
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Pavlović, Katarina
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visuell identitet ,Bildkonst ,visual identity ,Grafisk manual ,grafisk profil ,Brand guidelines ,logotype ,logotyp ,Visual Arts ,brand identity - Abstract
Föreliggande rapport har utförts i samarbete med Järfälla Atletklubb. Klubben behövde hjälp med att få riktlinjer i deras grafiska uttryck samt en uppdaterad version av deras logotyp. Järfälla Atletklubb tog hjälp av Högskolan Dalarna och författaren fick uppdraget att arbeta med klubben. Syftet med arbetet är att skapa en ny logotyp samt en grafisk profil åt klubben som sammanställts i en grafisk manual. Syftet med logotypen samt profilen är även att spegla atletklubbens kärnvärden, styrka, gemenskap och glädje. Studien har nyttjat Sless informationsdesignprocess som metod och strategi. Genom att ha fått en uppfattning om organisationen, konkurrenterna och klubbens värderingar arbetades det fram en ny grafisk profil. För metoden genomfördes det även en enkätundersökning samt ett experiment där Järfälla Atletklubb fick testa manualens användarvänlighet. Experimentet utfördes med tre av klubbens medlemmar och tillika styrelse. Enkätundersökningen syftade till att undersöka hur både medlemmar och klubbens målgrupp uppfattar den nya grafiska profilen samt om den representerar klubben och dess värdeord. Genom enkätundersökningen bekräftades det att den framtagna logotypen representerar de kärnvärden som Järfälla Atletklubb står för. Med resultatet från experimentet ska den grafiska profilen/manualen endast omfatta ett grundläggande koncept om logotyp, färg, typsnitt och bild. Manualen utformades med en kombination av text och förklarande grafik för att göra den så användarvänlig som möjligt. This report has been conducted in cooperation with Järfälla Atletklubb. The club needed help with guidelines in their graphic expressions as well as an updated version of their logo. Järfälla Atletklub reached out to Dalarna University and the writer got the assignment to work with the club. The purpose of the work is to create a new logo and a graphic profile for the club, compiled in a graphical manual. The purpose of the logo as well as the profile is also to reflect the athletic club's core values, strength, community and joy. The study has used Sless information design process as a method and strategy. By gaining an idea of the organization, the competitors and the club's values, a new graphic profile was developed. For this study, a survey was also conducted, as well as an experiment in which Järfälla Atletklub had to test the userfriendliness of the manual. The experiment was conducted with three of the club members. The survey was aimed at investigating how both members and the club's target group perceive the new graphical profile as well as whether it represents the club and its values. The survey confirmed that the generated logo represents the core values that Järfälla Atletklubb stands for. With the result of the experiment, the graphical profile/manual should only include a basic concept about logo, color, font and image. The manual was designed with a combination of text and explanatory graphics to make it as user-friendly as possible.
- Published
- 2018
25. Comparison of traditional and agile approach to manage product development projects
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Milenković, Mila, primary, Lalić, Bojan, primary, Pavlović, Katarina, primary, Berić, Ivana, primary, and Šobajić, Vesna, primary
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- 2019
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26. Contemporary challenges for project managers in Serbia
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Pavlović, Katarina, primary, Šobajić, Vesna, primary, Milenković, Mila, primary, Berić, Ivana, primary, and Berežljev, Ljiljana, primary
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- 2019
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27. LOKALNI VODIČ ZA PRIMENU LEKOVA KOD PACIJENATA OBOLELIH OD COVID-19.
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Janković, Slobodan M., Pavlović, Katarina P., Vukićević, Vladimir P., Gavrilović, Jagoda R., Folić, Marko M., Čanović, Predrag, Marjanović, Ružica, Mojsilović, Slavica, Stevanović, Nebojša, and Rosić, Nikola
- Abstract
Copyright of Medical Journal / Medicinski Časopis is the property of Serbian Medical Society, Section Kragujevac and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
28. Vägen till styrkelyftarens grafiska profil: Framtagning av logotyp och grafiskprofil för Järfälla Atletklubb
- Author
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Pavlović, Katarina and Pavlović, Katarina
- Abstract
Föreliggande rapport har utförts i samarbete med Järfälla Atletklubb. Klubben behövde hjälp med att få riktlinjer i deras grafiska uttryck samt en uppdaterad version av deras logotyp. Järfälla Atletklubb tog hjälp av Högskolan Dalarna och författaren fick uppdraget att arbeta med klubben. Syftet med arbetet är att skapa en ny logotyp samt en grafisk profil åt klubben som sammanställts i en grafisk manual. Syftet med logotypen samt profilen är även att spegla atletklubbens kärnvärden, styrka, gemenskap och glädje. Studien har nyttjat Sless informationsdesignprocess som metod och strategi. Genom att ha fått en uppfattning om organisationen, konkurrenterna och klubbens värderingar arbetades det fram en ny grafisk profil. För metoden genomfördes det även en enkätundersökning samt ett experiment där Järfälla Atletklubb fick testa manualens användarvänlighet. Experimentet utfördes med tre av klubbens medlemmar och tillika styrelse. Enkätundersökningen syftade till att undersöka hur både medlemmar och klubbens målgrupp uppfattar den nya grafiska profilen samt om den representerar klubben och dess värdeord. Genom enkätundersökningen bekräftades det att den framtagna logotypen representerar de kärnvärden som Järfälla Atletklubb står för. Med resultatet från experimentet ska den grafiska profilen/manualen endast omfatta ett grundläggande koncept om logotyp, färg, typsnitt och bild. Manualen utformades med en kombination av text och förklarande grafik för att göra den så användarvänlig som möjligt., This report has been conducted in cooperation with Järfälla Atletklubb. The club needed help with guidelines in their graphic expressions as well as an updated version of their logo. Järfälla Atletklub reached out to Dalarna University and the writer got the assignment to work with the club. The purpose of the work is to create a new logo and a graphic profile for the club, compiled in a graphical manual. The purpose of the logo as well as the profile is also to reflect the athletic club's core values, strength, community and joy. The study has used Sless information design process as a method and strategy. By gaining an idea of the organization, the competitors and the club's values, a new graphic profile was developed. For this study, a survey was also conducted, as well as an experiment in which Järfälla Atletklub had to test the userfriendliness of the manual. The experiment was conducted with three of the club members. The survey was aimed at investigating how both members and the club's target group perceive the new graphical profile as well as whether it represents the club and its values. The survey confirmed that the generated logo represents the core values that Järfälla Atletklubb stands for. With the result of the experiment, the graphical profile/manual should only include a basic concept about logo, color, font and image. The manual was designed with a combination of text and explanatory graphics to make it as user-friendly as possible.
- Published
- 2018
29. Interpretacija rezultata ispitivanja tla dobivenih statičkim piezo-penetrometrom (CPTU)
- Author
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Pavlović, Katarina and Kavur, Boris
- Subjects
statička penetracija ,TEHNIČKE ZNANOSTI. Interdisciplinarne tehničke znanosti. Inženjerstvo okoliša ,indeks tipa ponašanja tla ,statička penetracija, piezo-pentrometar, krutost tla, indeks tipa ponašanja tla ,TECHNICAL SCIENCES. Interdisciplinary Technical Sciences. Environmental Engineering ,piezo-pentrometar ,krutost tla - Abstract
U prvom dijelu rada dan je kratak opis statičke penetracije, samog uređaja, mjernih parametara te njena uloga i primjenjivost u istražnim radovima. Također, prikazani su i tehnički zahtjevi za CPT/CPTU opremu i postupak ispitivanja prema normi HRN EN ISO 22476- 1:2012. Nakon uvođenja u osnovne pojmove statičke penetracije, prikazane su novije mogućnosti interpretacije na temelju normaliziranih parametara prema modificiranom postupku (Robertson 2009). Uvođenjem tzv. indeksa tipa ponašanja tla (Ic) u proces interpretacije, pružena je mogućnost korištenja novih, modificiranih empirijskih korelacija za procjene: brzine posmičnih valova (vs) i krutosti tla (Go) te edometarskog modula (M), koje su za razliku od ranijih korelacija primjenjive i na krupnozrnato i na sitnozrnato tlo. Novi način interpretacije primjenjen je u ovom radu na praktičnim primjerima CPTU penetracija obavljenim u krupnozrnatom i sitnozrnatom tlu. Tako interpretirani parametri upoređeni su s rezultatima dobivenim starijim empirijskim korelacijama koje su bazirane uglavnom na otporu šiljka kao i s rezultatima dobivenim plosnatim dilatometrom (DMT) odnosno direktnim mjerenjima brzine posmičnih valova (vs). Obavljena je i analiza utjecaja greški mjerenja osnovnih mjernih parametara na vrijednosti interpretiranih parametara u uvjetima mekanog koherentnog tla za razrede primjene CPTU ispitivanja 1 i 2.
- Published
- 2017
30. Модел система менаџмента квалитета заснован на теорији комплексности
- Author
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Pavlović, Katarina B., Filipović, Jovan, Mijatović, Ivana, Putnik, Goran., and Spasojević Brkić, Vesna
- Subjects
систем менаџмента квалитета ,model ,complexity leadership ,adaptive ,административно ,модел ,quality management system ,лидерство које омогућава промене ,enabling ,адаптивно ,administrative ,комплексно лидерство - Abstract
Циљ рада је дефинисање и приказ универзалног иновираног модела система менаџмента квалитета заснованог на учењу и аспектима лидерства теорије комплексности. Како би се до овог циља дошло аутор је објединио учење, холистички приступ, системско размишљање, теорију комплексности, одрживост и промену парадигме у један иновирани модел, који треба да, као универзални модел, олакша организацијама прихватање и разумевање нове парадигме научне мисли, а то је парадигма комплексности. У до сада проученој литератури, није пронађен сличан модел. Примена иновираног модела треба да покаже да организације у прихватању нове парадигме, која не даје јасно дефинисане смернице, нити готово упутство за примену, могу да користе основу коју већ имају у формализованом систему менаџмента квалитета, који се може унапредити, на начине описане у раду, до нивоа комплексног адаптивног система. Као основа формализованог система квалитета узете су смернице стандарда ISO 9004:2009, за побољшање перформанси, због претпоставке да организације, које прате ове смернице већ имају јасну слику о томе шта се дешава око њих, али још увек нису у могућности да изађу изван ограничењастандарда и поред притиска који осећају. Идеја аутора била је да се иновираним моделом превазиђу ригидни оквири стандарда, а тиме оствари и боља интеракција са окружењем, већа флексибилност, иновативност и динамичност. Аутор је већ поменуту основу иновираног модела анализирао кроз сва три аспекта комплексног лидерства, адаптивног, административног и аспекта који омогућава промене. Из ове анализе произашла су питања, од којих је сачињен упитник. Упитник је упућен организацијама, а анализом добијених одговора потврђене су хипотезе изнете у раду. На тај начин дефинисан је један универзални модел система менаџмента квалитета, који може представљати основу данашњим организацијама за унапређење пословања и одрживу праксу, а који истовремено даје могућности за даље унапређење и прилагођавање актуелним захтевима организационог окружења. The aim of this dissertation is to define and display universal and innovated quality management system model based on learning and leadership aspects of complexity theory. In order to reach this goal the author has compiled learning, holistic approach, systems thinking, complexity theory, sustainability and change of paradigm shift in one amended model, which should, as a universal model, facilitate organization’s acceptance and understanding of the new paradigm of scientific thinking and that is complexity paradigm. Any similar model has not been found in the literature studied. Implementation of the innovated model should demonstrate, that organizations, in accepting new paradigm, which from its part does not give clearly defined guidelines nor “ready to use” procedure, can use as basis its formal quality management system, which can be improved in ways described in this dissertation, up to the level of a complex adaptive system. As basis of formal quality management system ISO 9004:2009 guidelines, for performance improvement, were taken, due to the condition that organizations which follow these already have a clear picture of what is happening around them, but are still not able to go ouside the restrictions imposed by the standard, regardless of pressure they feel. The author’s idea was to use this innovated model in order to overcome the rigid framework of standard and thereby achieve better interaction with organization’s environment, greater flexibility, innovation and dynamics. The author analyzed the above mentioned basis of innovated model, through all three aspects of complexity leadership, adaptive, administrative and enabling. From this analysis questions arose, which were put in a questionnaire. The questionnaire was sent to organizations and by analyzing responses obtained, hypotheses outlined in this dissertation were confirmed. This was the way to define one universal quality management system model, which could be the basis in today’s organizations, both for business promotion and sustainable practice, while at the same time giving opportunities for further improvement and adaption to current requirements imposed by organization’s environment.
- Published
- 2016
31. Agile Transformation in Clinical Research
- Author
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Pavlović, Katarina B., primary, Berić, Ivana, additional, and Berezljev, Ljiljana, additional
- Published
- 2018
- Full Text
- View/download PDF
32. Komunikacija između roditelja i djeteta
- Author
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Pavlović, Katarina and Lepičnik Vodopivec, Jurka
- Subjects
komunikacija ,razvoj ,SOCIAL SCIENCES. Pedagogy. Family Pedagogy ,obitelj ,DRUŠTVENE ZNANOSTI. Pedagogija. Obiteljska pedagogija ,pogreške - Abstract
Ovaj rad usmjerava se na prikazivanje komunikacije između roditelja i djece. Cilj je da se prikaže važnost pravilne komunikacije između roditelja i djece. Ključna riječ je komunikacija te se ona proteže kroz sva poglavlja. Središte rada je međugeneracijski intervju koji kroz dobivene rezultate prikazuje komunikacijske i odgojne razlike unutar jedne obitelji. Istraživanje obuhvaća tri generacije žena iste obitelji, pri čemu vidimo utjecaj vremena na promjene u načinima komunikacije. Kroz ostatak rada vidimo razlike u prijašnjim i sadašnjim načinima komunikacije. Vidi se važnost utjecaja rane komunikacije na bolji međuodnos roditelja i djece. Obiteljski odnosi i različite uloge njihovih članova dokazuju da u djetetovom životu nije bitna samo roditeljska uloga. Ono kroz prikaz raznih uloga u njegovu životu najbolje uči o različitostima koje ga čekaju izvan obiteljskoga okruženja. Glavna prepreka dobroj komunikaciji je barijera, a ovim putem prikazano je njezino uspješno prepoznavanje i rješavanje, a zatim za kraj uvid u važne korake koji roditeljima pomažu u kvalitetnijem uspostavljanju i poboljšavanju međuodnosa. This project is directing on representation parents –children communication. The goal is to represent the importance of proper communication between children and parents. The keyword is communications so it's representing trough all the chapters. The centre of the project is the intergenerational interview which trough the results represents communication and upbringing differences in the family. The research includes three generations of women from the same family, which we can see the time influence on the communication ways. Trough the restof the project we can see the differences in former and nowadays ways of communication. We can perceive the importance of the early communication to a better relationship between parents and children. The family relationship and the different roles their members proves that in the child's life isn't the parent role the only thing that matters. The child trough the representation different role in its life learns about the differences which waits him/ her out of the family surroundings on the best way. The main obstacle of the good communication is barrier, this way is showed its successfully recognition and solving, then for the end insight in the important steps which helps parents to establish and improve interrelations on a better way.
- Published
- 2016
33. Patient education before dialysis treatment
- Author
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Pavlović, Katarina, Pavlović, Draško, Kes, Petar, and Markeljević, Jasenka
- Subjects
hemodialysis ,peritoneal dialysis ,education of patients before dialysis treatment ,chronic kidney disease - Abstract
Kronična bubrežna bolest (KBB) jedan je od vodećih javnozdravstvenih problema sa značajnim porastom broja pacijenata svake godine. To je sindrom obilježen progresivnim i trajnim oštećenjem svih funkcija bubrega: ekskrecijske, metaboličke i endokrine. Kao vodeći uzroci u razvijenim zemljama spominju se dijabetička i hipertenzivna nefropatija. Bubrežna bolest može napredovati u kronično bubrežno zatajenje kroz nekoliko stadija, sve dok ne dostigne zadnji stadij kada je potrebno nadomještanje bubrežne funkcije metodama kao što je hemodijaliza, peritonealna dijaliza te na kraju transplantacija bubrega. Edukacija bolesnika prije liječenja dijalizom trebala bi biti osnova u skrbi za pacijente s KBB. Provođenje takvih sistematiziranih edukacijskih programa zahtjeva multidisciplinarni tim koji aktivno surađuje s pacijentima u programu. Cilj edukacijskih programa je informirati pacijente o samoj bolesti, te o načinima liječenja, te ih na taj način aktivno uključiti u odabir terapije koja najbolje odgovara njihovom stanju., Chronic kidney disease (CKD) is one of leading public health problems with significant increase in patient number each year. It is syndrome marked out by progressive and permanent damage of all kidney functions: excretion, metabolic and endocrine. Diabetic and hypertensive nephropathy is listed as its main cause in developed countries. Kidney disease can progress to chronic renal failure through several stages, until it reaches the last stage where is necessary to replace kidney function by methods such as hemodialysis, peritoneal dialysis an eventually kidney transplantation. Education of patients before dialysis treatment should be basic care for patients with CKD. Conduction of systematic educational programs requires multidisciplinary team which actively collaborates with patients in such program. Goals of educational programs are to inform patients about disease and treatments as well as to include them in choosing the best treatment for their condition.
- Published
- 2015
34. Analiza izvedenog stanja kružnog toka s desnim skretanjem u Varaždinu - Gospodarska ulica
- Author
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Pavlović, Katarina and Rezo, Milan
- Subjects
plateia ,TEHNIČKE ZNANOSTI. Interdisciplinarne tehničke znanosti. Inženjerstvo okoliša ,nivelete ,TECHNICAL SCIENCES. Interdisciplinary Technical Sciences. Environmental Engineering ,podjela prometnica - Abstract
U prvom dijelu ovog rada opisane su prometnice općenito, njihova podjela i osnovni elementi kako bismo dobili uvid u njihovu strukturu, važnost i namjenu. Svi opisi potkrijepljeni su slikama za bolje razumijevanje teksta. Opis samih prometnica predstavljaju bazu za glavnu temu ovog rada, a to su kružni tokovi. U ovom radu navedena je podjela kružnih tokova, njihova namjena, prednosti, nedostaci. Objašnjeni su svi osnovni elementi koje sadržava jedan kružni tok. Razrađeni su geometrijski elementi kružnih tokova: horizontalno i visinsko vođenje. Definiran je način izvođenja prometne signalizacije na kružnim tokovima. Kroz praktični dio rada napravljena je analiza izvedenog stanja kružnog toka s desnim skretanjem u Gospodarskoj ulici u Varaždinu. Opisana je izrada, od kreiranja digitalnog modela, uzdužnih i poprečnih profila pa sve do prometne opreme i uređivanja samog kružnog toka. Kroz to je ujedno i prikazan način rada programskog paketa Plateia koji služi za projektiranje prometnica.
- Published
- 2015
35. Модел система менаџмента квалитета заснован на теорији комплексности
- Author
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Filipović, Jovan, Mijatović, Ivana, Putnik, Goran., Spasojević Brkić, Vesna, Pavlović, Katarina B., Filipović, Jovan, Mijatović, Ivana, Putnik, Goran., Spasojević Brkić, Vesna, and Pavlović, Katarina B.
- Abstract
Циљ рада је дефинисање и приказ универзалног иновираног модела система менаџмента квалитета заснованог на учењу и аспектима лидерства теорије комплексности. Како би се до овог циља дошло аутор је објединио учење, холистички приступ, системско размишљање, теорију комплексности, одрживост и промену парадигме у један иновирани модел, који треба да, као универзални модел, олакша организацијама прихватање и разумевање нове парадигме научне мисли, а то је парадигма комплексности. У до сада проученој литератури, није пронађен сличан модел. Примена иновираног модела треба да покаже да организације у прихватању нове парадигме, која не даје јасно дефинисане смернице, нити готово упутство за примену, могу да користе основу коју већ имају у формализованом систему менаџмента квалитета, који се може унапредити, на начине описане у раду, до нивоа комплексног адаптивног система. Као основа формализованог система квалитета узете су смернице стандарда ISO 9004:2009, за побољшање перформанси, због претпоставке да организације, које прате ове смернице већ имају јасну слику о томе шта се дешава око њих, али још увек нису у могућности да изађу изван ограничењастандарда и поред притиска који осећају. Идеја аутора била је да се иновираним моделом превазиђу ригидни оквири стандарда, а тиме оствари и боља интеракција са окружењем, већа флексибилност, иновативност и динамичност. Аутор је већ поменуту основу иновираног модела анализирао кроз сва три аспекта комплексног лидерства, адаптивног, административног и аспекта који омогућава промене. Из ове анализе произашла су питања, од којих је сачињен упитник. Упитник је упућен организацијама, а анализом добијених одговора потврђене су хипотезе изнете у раду. На тај начин дефинисан је један универзални модел система менаџмента квалитета, који може представљати основу данашњим организацијама за унапређење пословања и одрживу праксу, а који истовремено даје могућности за даље унапређење и прилагођавање актуелним захтевима организационог окружења., The aim of this dissertation is to define and display universal and innovated quality management system model based on learning and leadership aspects of complexity theory. In order to reach this goal the author has compiled learning, holistic approach, systems thinking, complexity theory, sustainability and change of paradigm shift in one amended model, which should, as a universal model, facilitate organization’s acceptance and understanding of the new paradigm of scientific thinking and that is complexity paradigm. Any similar model has not been found in the literature studied. Implementation of the innovated model should demonstrate, that organizations, in accepting new paradigm, which from its part does not give clearly defined guidelines nor “ready to use” procedure, can use as basis its formal quality management system, which can be improved in ways described in this dissertation, up to the level of a complex adaptive system. As basis of formal quality management system ISO 9004:2009 guidelines, for performance improvement, were taken, due to the condition that organizations which follow these already have a clear picture of what is happening around them, but are still not able to go ouside the restrictions imposed by the standard, regardless of pressure they feel. The author’s idea was to use this innovated model in order to overcome the rigid framework of standard and thereby achieve better interaction with organization’s environment, greater flexibility, innovation and dynamics. The author analyzed the above mentioned basis of innovated model, through all three aspects of complexity leadership, adaptive, administrative and enabling. From this analysis questions arose, which were put in a questionnaire. The questionnaire was sent to organizations and by analyzing responses obtained, hypotheses outlined in this dissertation were confirmed. This was the way to define one universal quality management system model, which could be the basis in today’s organizati
- Published
- 2016
36. Modeli i proces donošenja odluka
- Author
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Pavlović, Katarina
- Subjects
Odlučivanje ,modeli odlučivanja ,proces donošenje odluka - Abstract
Modeli i proces donošenja odluka
- Published
- 2013
37. Laboratorijska analiza hemolitičkih svojstava materijala koji dolaze u kontakt sa krvlju - uporedna primena dve varijante metode ispitivanja prema standardu ASTM F756 u skladu sa ISO 10993-4
- Author
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Pavlović, Katarina B., Božanić, Vojislav, Stanojević, Jasna V., Milićević, Vesna, Ilić, Bojan, Pavlović, Katarina B., Božanić, Vojislav, Stanojević, Jasna V., Milićević, Vesna, and Ilić, Bojan
- Abstract
U ovom radu prikazano je poređenje rezultata dve varijante in vitro metode ispitivanja prema standardu ASTM F756 u skladu sa ISO 10993-4 hemolitičkih svojstava šest polaznih materijala (Polipropilen Moplen EP 540 P, Polikarbonat bezbojan 164 R- 112, Polikarbonat braon 164 R-51918, Polietilen NG 3026 K, Polietilen NG - Purell GB 7250, Polietilen VG - Hiplex 5502) za proizvodnju medicinskih sredstava i jednog materijala (Polietilen NG granulat) za proizvodnju boca za infuzione rastvore. Jedna varijanta metode zasniva se na direktnom kontaktu polaznog materijala sa svinjskom krvlju, a druga na dobijanju ekstrakta polaznog materijala autoklaviranjem i kontaktu tako dobijenog ekstrakta sa svinjskom krvlju. Na osnovu dobijenih rezultata zaključeno je da svi materijali zadovoljavaju kriterijume prihvatljivosti i to u slučaju obe varijante metode ispitivanja, kao i da metoda direktnog kontakta ima veću osetljivost od metode u kojoj su korišćeni ekstrakti ovih materijala. ., The presence of hemolytic material in contact with blood may produce increased levels of blood cell lysis and increased levels of plasma hemoglobin. This may induce toxic effects or other effects which may stress the kidneys or other organs. In this paper two variants of in vitro method and obtained results' comparison were presented for testing of hemolytic properties of six raw materials (polipropylene Moplen EP 540 P, policarbonate colorless 164 R-112, policarbonate brown 164 R-51918, polietylene NG 3026 K, polietylene NG - Purell GB 7250, polietylene VG - Hiplex 5502) for medical device manufacturing and one raw material (polietylen NG granulate) used for infusion solutions plastic bottles manufacturing. One of the method variants relies on direct contact of the raw material with swine blood and the other on contact of extract of the material with swine blood. Both variants imply reading of the absorbance of the supernatant after tubes were incubated and centrifuged. According to the values obtained and using the standard curve free hemoglobin concentration is determined and based on this percentage hemolysis of raw material. Positive and negative controls were used in both variants where water for injection (WFI) was used as positive control in which partial or complete hemolysis of erythrocytes occurs due to osmotic shock and phosphate buffer saline was used as negative control with no hemolytic property. In this paper a comparison of results obtained by both method variants for testing of seven raw materials is presented, while these conclusions cannot be used neither for all materials, nor for all applications without preliminary testing using both variants and then choosing more sensitive and more reliable one. It was shown and stated in the paper as well that incubation time being 3, 15 or 24 h, had no impact on the variants with direct contact sensitivity. This comparative approach was used for drawing conclusions in terms of suitability for application o
- Published
- 2010
38. Značaj usaglašenosti laboratorija farmaceutske industrije sa zahtevima međunarodnih standarda u kontekstu povećanja konkurentnosti
- Author
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Božanić, Vojislav, Pavlović, Katarina B., Milićević, Vesna, Ilić, Bojan, Božanić, Vojislav, Pavlović, Katarina B., Milićević, Vesna, and Ilić, Bojan
- Abstract
U ovom radu pošlo se od značaja usaglašenosti laboratorija farmaceutske industrije sa zahtevima međunarodnih standarda sa aspekta povećanja konkurentnosti farmaceutskih kompanija. Prikazana je komparativna analiza zahteva standarda ISO/IEC 17025 koji se primenjuju dobrovoljno, ali koji su već implementirani u velikom broju kompanija širom sveta i zahteva cGMP (current Good Manufacturing Practice), koji će od 2010. godine biti deo zakonske regulative u Republici Srbiji, i to segmenta koji se odnosi na laboratorije kontrole kvaliteta u preduzećima farmaceutske industrije. Cilj ovoga rada je da ukaže na mogućnost istovremenog zadovoljenja i jednih i drugih zahteva, čime bi se laboratorijama farmaceutske industrije otvorio put za različite vidove međulaboratorijske saradnje u domaćim i u međunarodnim okvirima., Current Good Manufacturing Practice (cGMP) being a legal regulation in developed countries will become a legal regulation in Republic of Serbia starting with March 2010. In this paper comparative analysis between requirements of standard ISO/IEC 17025 and requirements of cEU GMP is shown. Considering the fact that in Republic of Serbia no pharmaceutical industry laboratory has been accredited according to requirements of ISO/IEC 17025, while keeping in mind that more than 90% of these laboratories have not fulfilled cEU GMP requirements, this paper aimed at pointing to the possibility of fulfilling both of mentioned requirements at the same time, which would open the way to different types of interlaboratory cooperation for pharmaceutical quality control laboratories and contribute to improving competitiveness of pharmaceutical companies. Accreditation, especially in the case of pharmaceutical quality control laboratories, is important because it guaranties the level of organizational and technical competency. It could easily be said that accreditation is becoming a must in quality control of products in order for the organization to be able to gain a leading role in the global market. Both accreditation and cGMP show the organization's commitment to having products of highest quality level. Considering the above mentioned facts, it is of greatest advantage for pharmaceutical quality control laboratories to fulfill both requirements of ISO/IEC 17025 and cGMP and reach total compliance. The aim of doing this lies in an easier acceptance of pharmaceutical products in different markets, overcoming technical barriers and affirmation of quality as key factor in reaching competitiveness, while keeping in mind the importance of strategic and competitive positioning in the global market.
- Published
- 2009
39. LEAN AND SIX SIGMA CONCEPTS - APPLICATION IN PHARMACEUTICAL INDUSTRY.
- Author
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Pavlović, Katarina and Božanić, Vojislav
- Published
- 2011
40. Hit Selection of Dipeptidyl Peptidase-4 Inhibitors Bearing Thieno[2,3-d]Pyrimidine Scaffold.
- Author
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Pavlović KT, Ilić BS, Dimov S, Yancheva D, Mavrova AT, and Šmelcerović A
- Abstract
The thieno[2,3-d]pyrimidine fragment is in the structure of many drug-like candidate derivatives with a wide range of biological activities. However, very few dipeptidyl peptidase-4 (DPP-4) inhibitors with this building block are currently known. Here, the selection of a novel DPP-4 inhibitor based on the thienopyrimidine scaffold is reported. In the performed study, ethyl 4-amino-5-methyl-2-(3-(trifluoromethyl)phenyl)thieno[2,3-d]pyrimidine-6-carboxylate (compound 22) demonstrated DPP-4 inhibitory potential about twice higher than that of the reference inhibitor diprotin A. The manner of inhibition is noncompetitive, a rare type among DPP-4 inhibitors. The molecular docking highlighted the importance of Ser349, Asn377, Glu378, Phe396, and Asp588 in forming the inhibitor/DPP-4 complex. Compound 22 might be useful as a source of ideas contributing to the design and further changes and optimizations of thieno[2,3-d]pyrimidine-based DPP-4 inhibitors., (© 2024 Wiley‐VHCA AG, Zurich, Switzerland.)
- Published
- 2024
- Full Text
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