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1. Safety and efficacy of the feed additive consisting of Vitamin B2/Riboflavin produced by Eremothecium ashbyi CCTCCM 2019833 for all animal species (Hubei Guangji Pharmaceutical Co., Ltd)

Author

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Fašmon Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Georges Brantom, Pier Sandro Cocconcelli, Boet Glandorf, Lieve Herman, Miguel Prieto Maradona, Maria Saarela, Kettil Svensson, Luca Tosti, Jaume Galobart, Paola Manini, Elisa Pettenati, Fabiola Pizzo, Jordi Tarrés‐Call, and Montserrat Anguita

Subjects
Vitamin B2/Riboflavin, Eremothecium ashbyi, nutritional additive, vitamins, safety, efficacy, Nutrition. Foods and food supply, TX341-641, Chemical technology, TP1-1185
Abstract

Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the feed additive Vitamin B2/Riboflavin produced by Eremothecium ashbyi CCTCCM 2019833 for all animal species and categories. The additive contains a minimum content of riboflavin of 5%. The production strain has been characterised and data showed that viable cells are not present in the final additive. The additive is not a skin or eye irritant nor a skin sensitiser, but it is considered to be a respiratory sensitiser. The lack of data on the toxicological profile of the additive, including its genotoxic potential, did not allow the Panel to conclude on the safety of the additive for the target species, consumers and users. The FEEDAP Panel concluded that the use of the product as a feed additive poses no concerns for the environment. The additive under assessment is effective in covering the animals’ requirements for vitamin B2 when administered via feed.

Published
2021
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2. Safety and efficacy of the feed additive consisting of Vitamin B2/Riboflavin produced by Eremothecium ashbyi CCTCCM 2019833 for all animal species (Hubei Guangji Pharmaceutical Co., Ltd)

Author

Maria Saarela, Vasileios Bampidis, Montserrat Anguita, Secundino López Puente, Alena Pechová, Mojca Fašmon Durjava, Jaume Galobart, Elisa Pettenati, Francesca Marcon, Miguel Prieto Maradona, Paola Manini, Luca Tosti, Birgit Dusemund, Ruud Woutersen, Giovanna Azimonti, Efsa Panel on Additives, Marta López-Alonso, Yolanda Sanz, Maria de Lourdes Bastos, Boet Glandorf, Fabiola Pizzo, Maryline Kouba, Henrik Christensen, Lieve Herman, Mariana Petkova, Roberto Edoardo Villa, Paul Georges Brantom, Jordi Tarrés-Call, Kettil Svensson, Pier Sandro Cocconcelli, Fernando Ramos, and Baltasar Mayo

Subjects
safety, Nutrition. Foods and food supply, Veterinary (miscellaneous), Feed additive, Chemical technology, Eremothecium ashbyi, efficacy, nutritional additive, Riboflavin, Plant Science, TP1-1185, Biology, vitamins, Microbiology, Anim2953, Scientific Opinion, Animal Science and Zoology, Parasitology, TX341-641, Food science, Animal species, Vitamin B2/Riboflavin, Food Science, Vitamin b2
Abstract

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the feed additive Vitamin B2/Riboflavin produced by Eremothecium ashbyi CCTCCM 2019833 for all animal species and categories. The additive contains a minimum content of riboflavin of 5%. The production strain has been characterised and data showed that viable cells are not present in the final additive. The additive is not a skin or eye irritant nor a skin sensitiser, but it is considered to be a respiratory sensitiser. The lack of data on the toxicological profile of the additive, including its genotoxic potential, did not allow the Panel to conclude on the safety of the additive for the target species, consumers and users. The FEEDAP Panel concluded that the use of the product as a feed additive poses no concerns for the environment. The additive under assessment is effective in covering the animals’ requirements for vitamin B2 when administered via feed.

Published
2021

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