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1. PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer

2. HIV-1-induced nuclear invaginations mediated by VAP-A, ORP3, and Rab7 complex explain infection of activated T cells

3. Novel [1,3,4]Thiadiazole[3,2-a]pyrimidin-5-ones as Promising Biofilm Dispersal Agents against Relevant Gram-Positive and Gram-Negative Pathogens

4. Interrelationship between miRNA and splicing factors in pancreatic ductal adenocarcinoma

5. Nortopsentins as Leads from Marine Organisms for Anticancer and Anti-Inflammatory Agent Development

6. A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation

7. 1,3,4-Oxadiazole and 1,3,4-Thiadiazole Nortopsentin Derivatives against Pancreatic Ductal Adenocarcinoma: Synthesis, Cytotoxic Activity, and Inhibition of CDK1

8. Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma

9. Synthesis and Antioxidative Properties of 1,2,3,4-Tetrahydropyridine Derivatives with Different Substituents in 4-Position

10. Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum

11. CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin

12. A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells

13. Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation

14. 3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1H-Indole Derivatives as New Anticancer Agents in the Treatment of Pancreatic Ductal Adenocarcinoma

15. 3-[4-(1H-Indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, Nortopsentin Analogues with Antiproliferative Activity

16. Synthesis and Antiproliferative Activity of Thiazolyl-bis-pyrrolo[2,3-b]pyridines and Indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, Nortopsentin Analogues

18. Synthesis of the New Ring System Bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and Its Deaza Analogue

19. New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity

20. Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin

22. New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation

28. New Tripentone Analogs with Antiproliferative Activity

29. Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

31. Biofilm Formation as Valuable Target to Fight against Severe Chronic Infections

32. Recent Developments in the Inhibition of Bacterial Adhesion as Promising Anti-Virulence Strategy

33. Multi or Single-Kinase Inhibitors to Counteract Drug Resistance in Cancer: What is New?

34. Development of a new indole derivative dry powder for inhalation for the treatment of biofilm-associated lung infections

35. Nobiletin and xanthohumol counteract the TNFα-mediated activation of endothelial cells through the inhibition of the NF-κB signaling pathway

36. Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm‐Associated Infections

37. New Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives Inhibit FAK Phosphorylation and Potentiate the Antiproliferative Effects of Gemcitabine Through Modulation of the Human Equilibrative Nucleoside Transporter-1 in Peritoneal Mesothelioma

38. Eight-membered heterocycles with two heteroatoms in a 1,3-relationship of interest in medicinal chemistry

41. Synthesis and pharmacological evaluation of enantiomerically pure endo-configured KOR agonists with 2-azabicyclo[3.2.1]octane scaffold

42. 1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation

43. Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification

44. SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance

45. Eight-Membered Rings With Two Heteroatoms 1,5

46. Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma

47. Interrelationship between miRNA and splicing factors in pancreatic ductal adenocarcinoma

48. Novel strategies in the war against antibiotic resistance

49. Nobiletin and xanthohumol sensitize colorectal cancer stem cells to standard chemotherapy

50. 1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A

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