Author: "Patricia Alonso" - Searchworks@Jio Institute Digital Library Search Results

354 results on '"Patricia Alonso"'

1. Respiratory, cardio-metabolic and neurodevelopmental long-term outcomes of moderate to late preterm birth: not just a near term-population. A follow-up study

Author: Patricia Alonso-Lopez, Maria Arroyas, Maite Beato, Sara Ruiz-Gonzalez, Iciar Olabarrieta, and Maria Luz Garcia-Garcia
Subjects: moderate to late preterm, premature birth, asthma, lung function, cardiovascular risk, metabolic risk, Medicine (General), R5-920
Abstract: IntroductionModerate-to-late preterm infants constitute the majority within the preterm infant population. Most research on preterm infants has focused on very preterm children, often treating moderate-to-late preterm infants as similar to full-term infants. Our objective was to compare clinical, respiratory, cardio-metabolic and neurodevelopmental outcomes in adolescents aged 12–15 years born moderate and late preterm with a control group of the same age born full-term.MethodsObservational cross-sectional study, comparing moderate-to-late preterm (32–36+6 weeks’ gestational age) with full-term adolescents (37–41+6 weeks’ gestational age; 75 each group). Perinatal and neonatal history were collected as well as data on respiratory evolution (ISAAC questionnaire for asthma symptoms for adolescents 13–14 years), anthropometric values, learning difficulties, behavioral test (screening questionnaire for high-performance autism spectrum disorder and evaluation test for attention deficit hyperactivity disorder), skin prick test, pulmonary function test, echocardiogram and blood pressure. A blood test with metabolic profile was conducted.ResultsModerate-to-late preterm adolescents had more current asthma [p = 0.008, OR3 (95% CI 1.26–7.14)] and longer duration of combined treatments to control asthma (inhaled corticosteroids and anti-leukotrienes; p = 0.048). Forced vital capacity
Published: 2024
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2. Las fotografías de las primeras empleadas del Banco de España (1905-1907)

Author: Patricia Alonso del Torno
Subjects: fotografía de trabajadores, fotografía documental, mujeres, empleo femenino, archivos fotográficos, Banco de España, Bibliography. Library science. Information resources
Abstract: Este artículo presenta la serie de los primeros retratos fotográficos de identificación de empleados del Banco de España que fueron realizados entre 1905 y 1907 por José Irigoyen Zabaleta, primer fotógrafo en plantilla de la entidad. De los 280 retratos conservados de la citada serie, el artículo centra su atención en las fotografías de las tres únicas mujeres del conjunto, Carmen Esteban, Engracia Herranz y Calixta Bravo. De ellas, Carmen y Engracia fueron las primeras empleadas que ingresaron en el Banco de España, lo hicieron en 1901 como mozas encargadas del servicio de limpieza. El artículo ofrece el contexto histórico de la creación de los retratos y algunos datos para mejorar su comprensión, a través del análisis de las propias fotografías, de los documentos contenidos en sus expedientes personales y de otras fuentes documentales y bibliográficas.
Published: 2024
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3. Application of Cinnamon Essential Oil in Active Food Packaging: A Review

Author: Patricia Alonso, Sandra Fernández-Pastor, and Ana Guerrero
Subjects: active packaging, antimicrobial properties, antioxidant activity, films, cinnamon, edible coating, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
Abstract: Active packaging allows for preserving the properties of food, extending shelf life, and safeguarding food safety through the interaction of their diverse components with the product. The incorporation of essential oils, particularly cinnamon essential oil, as active components is emerging as an increasingly relevant alternative to synthetic additives. This work aims to provide an overview of the application of cinnamon essential oil as a bioactive compound in food packaging. Cinnamon essential oil exhibits a highly variable composition, with cinnamaldehyde standing out as one of the predominant components responsible for the antimicrobial properties. Phenolic compounds, on the other hand, endow the oil with outstanding antioxidant activity. The application of this oil in active packaging, whether in the form of films or coatings, has demonstrated a significant improvement in optical, mechanical, and water vapor barrier properties. Moreover, its ability to inhibit microbial growth and lipid oxidation in the applied foods has been evidenced. However, despite the promising prospects of using essential oils in active packaging for food preservation, detailed regulation is still required for industrial-level implementation.
Published: 2024
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4. Nasal TSLP and periostin in infants with severe bronchiolitis and risk of asthma at 4 years of age

Author: Maria Luz Garcia-Garcia, Beatriz Sastre, Maria Arroyas, Maite Beato, Patricia Alonso, José Manuel Rodrigo-Muñoz, Victoria Del Pozo, Inmaculada Casas, and Cristina Calvo
Subjects: Bronchiolitis, Asthma, Recurrent wheezing, Periostin, Thymic stromal lymphopoietin (TSLP), Respiratory syncytial virus (RSV), Diseases of the respiratory system, RC705-779
Abstract: Abstract Background Severe bronchiolitis is often associated with subsequent respiratory morbidity, mainly recurrent wheezing and asthma. However, the underlying immune mechanisms remain unclear. The main goal of this study was to investigate the association of nasal detection of periostin and thymic stromal lymphopoietin (TSLP) during severe bronchiolitis with the development of asthma at 4 years of age. Methods Observational, longitudinal, post-bronchiolitis, hospital-based, follow-up study. Children hospitalized for bronchiolitis between October/2013 and July/2017, currently aged 4 years, included in a previous study to investigate the nasal airway secretion of TSLP and periostin during bronchiolitis, were included. Parents were contacted by telephone, and were invited to a clinical interview based on a structured questionnaire to obtain information on the respiratory evolution. The ISAAC questionnaire for asthma symptoms for 6–7-year-old children, was also employed. Results A total of 248 children were included (median age 4.4 years). The mean age at admission for bronchiolitis was 3.1 (IQR: 1.5–6.5) months. Overall, 21% had ever been diagnosed with asthma and 37% had wheezed in the last 12 months. Measurable nasal TSLP was detected at admission in 27(11%) cases and periostin in 157(63%). The detection of nasal TSLP was associated with the subsequent prescription of maintenance asthma treatment (p = 0.04), montelukast (p = 0.01), and the combination montelukast/inhaled glucocorticosteroids (p = 0.03). Admissions for asthma tended to be more frequent in children with TSLP detection (p = 0.07). In the multivariate analysis, adjusting for potential confounders, the detection of TSLP remained independently associated with chronic asthma treatment prescription (aOR:2.724; CI 1.051–7.063, p:0.04) and with current asthma (aOR:3.41; CI 1.20–9.66, p:0.02). Nasal detection of periostin was associated with lower frequency of ever use of short-acting beta2-agonists (SABA) (p = 0.04), lower prevalence of current asthma (p = 0.02), less prescription of maintenance asthma treatment in the past 12 months (p = 0.02, respectively). In the multivariate analysis, periostin was associated with lower risk of asthma at 4 years, independently of the atopic status (aOR:0.511 CI 95% 0.284–0.918, p:0.025). Conclusions Our results show a positive correlation between nasal TSLP detection in severe bronchiolitis and the presence of current asthma, prescription of asthma maintenance treatment and respiratory admissions up to the age of 4 years. By contrast, we found a protective association between nasal periostin detection and current asthma at 4 years, ever diagnosis of asthma, maintenance asthma treatment prescription, and respiratory admissions.
Published: 2023
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5. Contextualization of a Radical Language Detection System Through Moral Values and Emotions

Author: Patricia Alonso Del Real and Oscar Araque
Subjects: Machine learning, moral values, natural language processing, radicalization detection, sentiment analysis, Electrical engineering. Electronics. Nuclear engineering, TK1-9971
Abstract: The popularity of current communication technologies has boosted the spread of polarization and radical ideologies, which can be exploited by terrorist organizations. Building upon previous research, this work focuses on the task of automatic radicalization detection in texts using natural language processing and machine learning techniques. In this way, we investigate the effectiveness of integrating moral values through the Moral Foundations Theory (MFT). Moral values play a crucial role in identifying ideological inclinations and can have a significant impact on the radicalization detection task. Our approach distinguishes itself in the feature extraction stage, leveraging moral values, emotions, and similarity-based features that utilize word embeddings. Additionally, we thoroughly evaluate the proposed representations with three distinct datasets that model radicalization and use the SHAP method to gain relevant insight into the models’ reasoning.
Published: 2023
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6. Cellular Response of Adapted and Non-Adapted Tetrahymena thermophila Strains to Europium Eu(III) Compounds

Author: Patricia Alonso, Javier Blas, Francisco Amaro, Patricia de Francisco, Ana Martín-González, and Juan Carlos Gutiérrez
Subjects: europium, lipid metabolism, bioaccumulation, oxidative stress, gene expression, Tetrahymena thermophila, Biology (General), QH301-705.5
Abstract: Europium is one of the most reactive lanthanides and humans use it in many different applications, but we still know little about its potential toxicity and cellular response to its exposure. Two strains of the eukaryotic microorganism model Tetrahymena thermophila were adapted to high concentrations of two Eu(III) compounds (EuCl3 or Eu2O3) and compared to a control strain and cultures treated with both compounds. In this ciliate, EuCl3 is more toxic than Eu2O3. LC50 values show that this microorganism is more resistant to these Eu(III) compounds than other microorganisms. Oxidative stress originated mainly by Eu2O3 is minimized by overexpression of genes encoding important antioxidant enzymes. The overexpression of metallothionein genes under treatment with Eu(III) compounds supports the possibility that this lanthanide may interact with the -SH groups of the cysteine residues from metallothioneins and/or displace essential cations of these proteins during their homeostatic function. Both lipid metabolism (lipid droplets fusing with europium-containing vacuoles) and autophagy are involved in the cellular response to europium stress. Bioaccumulation, together with a possible biomineralization to europium phosphate, seems to be the main mechanism of Eu(III) detoxification in these cells.
Published: 2024
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7. Fondos de Conocimiento Familiar e Intervención Educativa. Comprender las circunstancias sociohistóricas de los estudiantes

Author: Patricia Alonso Ruido
Subjects: Education, Education (General), L7-991
Published: 2023
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8. Victims of Child Grooming: An Evaluation in University Students

Author: Patricia Alonso-Ruido, Iris Estévez, Bibiana Regueiro, and Cristina Varela-Portela
Subjects: grooming, sextortion, child sexual abuse, pornography, gender, educational intervention, Social sciences (General), H1-99
Abstract: The appearance of new ways of committing sexual violence via technological media and virtual spaces has produced countless situations where sexual abuse of minors may occur. This is the digital scenario surrounding the phenomenon of grooming. The present study focuses on analyzing grooming experienced by Spanish university students during childhood. The sample comprised 3293 students in higher education, 68.3% of whom were female, 30.5% were male, and 1.2% identified as non-binary. The mean age was 18.83 years (SD = 2.28). The results confirmed that sexual abuse of minors has moved towards virtual environments, indicating a prevalence of 12.2% for grooming, which was more likely to have affected women and non-binary people. In addition, student victims of grooming were more often also victims of sextortion. Consumption of pornography was also shown to be particularly important, with the results indicating that students who consumed it and started consuming it before they were 16 years old were more often victims of grooming. These findings should encourage the educational community to develop preventive actions that match the reality of online child sexual abuse. In summary, the only path towards preventing and detecting grooming is to invest in high-quality digital education and sex education from a gender perspective.
Published: 2024
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9. Antibiotic Utilization in Hospitalized Children with Bronchiolitis: A Prospective Study Investigating Clinical and Epidemiological Characteristics at a Secondary Hospital in Madrid (2004–2022)

Author: María Luz García-García, Sonia Alcolea, Patricia Alonso-López, Clara Martín-Martín, Guadalupe Tena-García, Inmaculada Casas, Francisco Pozo, Ana Méndez-Echevarría, Jara Hurtado-Gallego, and Cristina Calvo
Subjects: antibiotics, bronchiolitis, respiratory virus, respiratory syncytial virus, human bocavirus, human adenovirus, Medicine
Abstract: Bronchiolitis is a viral respiratory infection, with respiratory syncytial virus (RSV) being the most frequent agent, requiring hospitalization in 1% of affected children. However, there continues to be a noteworthy incidence of antibiotic prescription in this setting, further exacerbating the global issue of antibiotic resistance. This study, conducted at Severo Ochoa Hospital in Madrid, Spain, focused on antibiotic usage in children under 2 years of age who were hospitalized for bronchiolitis between 2004 and 2022. In that time, 5438 children were admitted with acute respiratory infection, and 1715 infants (31.5%) with acute bronchiolitis were included. In total, 1470 (87%) had a positive viral identification (66% RSV, 32% HRV). Initially, antibiotics were prescribed to 13.4% of infants, but this percentage decreased to 7% during the COVID-19 pandemic thanks to adherence to guidelines and the implementation of rapid and precise viral diagnostic methods in the hospital. HBoV- and HAdV-infected children and those with viral coinfections were more likely to receive antibiotics in the univariate analysis. A multivariate logistic regression analysis revealed a statistically independent association between antibiotic prescription and fever > 38 °C (p < 0.001), abnormal chest-X ray (p < 0.001), ICU admission (p = 0.015), and serum CRP (p < 0.001). In conclusion, following guidelines and the availability of rapid and reliable viral diagnostic methods dramatically reduces the unnecessary use of antibiotics in infants with severe bronchiolitis.
Published: 2023
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10. Fractional Sobolev embeddings and algebra property: A dyadic view

Author: Ruiz, Patricia Alonso and Fragkiadaki, Valentia
Subjects: Mathematics - Classical Analysis and ODEs, Mathematics - Functional Analysis, 42B35, 26A33, 42A99
Abstract: This paper revisits classical fractional Sobolev embedding theorems and the algebra property of the fractional Sobolev space $H^s(\mathbb{R})$ by means of Haar functions and dyadic decompositions. The aim is to provide an alternative, hands-on approach without Fourier transform that may be transferred to settings where the latter is not available. Explicit counterexamples are constructed to show the failure of the algebra property in the low-regularity regime., Comment: 15 pages
Published: 2024

11. Validación de la Escala de Comportamientos de Sexting en Adolescentes: Prevalencia y Consecuencias Asociadas

Author: Yolanda Rodríguez-Castro, Patricia Alonso-Ruido, Antonio González-Fernández, María Lameiras-Fernández, and Jose-María Faílde-Garrido
Subjects: sexting, education, scale, validity, coercion, blackmail, Philosophy. Psychology. Religion, Psychology, BF1-990
Abstract: El objetivo de este estudio fue triple: validar una versión de la Escala de Comportamientos de Sexting en adolescentes, evaluar la prevalencia de dichos comportamientos y determinar sus consecuencias asociadas. Participaron un total de 1,271 estudiantes(50.8% chicas), con una media de edad de 15.6 (DT = 1.13). Los resultados muestran a través del análisis factorial confirmatorio un buen ajuste por el modelo bidimensional formado por ítems que se agrupan en el envío de fotos y/o vídeos (α = .83) y el envío de mensajes de texto con contenido erótico/sexual (α = .83). Se ha identificado que el 52.8% de los adolescentes han llevado a cabo conductas de sexting, siendo mayor el envío de textos erótico/sexuales (91.7%) que de fotos y/o vídeos (57.8%), y que los chicos son los que más contenidos envían. Además, el 11.6% de los adolescentes fueron obligados a enviar contenido de sexting y el 5.5% fueron chantajeados.
Published: 2021
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12. College Students’ Stereotyped Beliefs

Author: Patricia Alonso-Ruido, Iris Estévez, Cristina Varela-Portela, and Bibiana Regueiro
Subjects: stereotype, gender roles, gender equality, university students, education, Social Sciences
Abstract: Over recent years, socio-political discourse has been full of language aimed at reaching gender equality. This is a complex goal that should address the underlying bases of inequality—gender stereotypes that continue to legitimize unequal consideration and treatment. It is also a reality that universities are not exempt from. The objective of this study was to analyze university students’ stereotyped beliefs and look at the differences based on self-identified gender and branch of knowledge. The analysis looked at a sample of 3433 university students (67.9% women), aged between 17 and 56 (M = 18.95; SD = 2.35) and reported low rates of prevalence of stereotyped beliefs, with significantly higher means in men and in engineering students. The survival of gender stereotypes in a population who were born and raised in a legally egalitarian society points to the importance of education programs aimed at university teachers that would give them the capacity to incorporate a gender perspective in all disciplines, especially those disciplines reporting greater adherence to stereotyped beliefs.
Published: 2023
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13. ¿Pornografía al alcance de un clic? Una revisión de la literatura reciente sobre adolescentes españoles

Author: Patricia Alonso Ruido, María Sande Muñiz, and Bibiana Regueiro
Subjects: adolescentes, consumo de pornografía, perspectiva de género, educación sexual, Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: Las tecnologías de la información y la comunicación (TICs) proporcionan un acceso constante e inmediato a una amplia gama de información y recursos. Los/as adolescentes, habitualmente considerados/as nativos/as digitales, utilizan los medios tecnológicos y los espacios virtuales para explorar su dimensión sexuada accediendo a contenidos pornográficos. La revisión bibliográfica que se presenta en este trabajo tiene un doble objetivo: evaluar el consumo de pornografía entre los adolescentes españoles y analizar las variables asociadas desde una perspectiva de género El estudio consiste en una revisión sistemática de trabajos sobre adolescentes españoles publicados entre 2016 y 2020. Los resultados muestran que acceden a contenidos pornográficos por primera vez alrededor de los 12 años, y que el consumo de pornografía se consolida durante la adolescencia, especialmente en el caso de los varones, que son los principales consumidores. También muestran que la pornografía es una fuente de información para muchos adolescentes que no reciben suficiente educación sexual ni en casa ni en la escuela. El consumo de pornografía durante la adolescencia está asociado a una serie de consecuencias, como el sexismo, la violencia y el consumo de sustancias, y puede conducir a una visión distorsionada de la sexualidad. La situación que revelan estos resultados pone de manifiesto la necesidad de apoyar la educación sexual en la familia y en la escuela para dotar a los jóvenes de las herramientas necesarias para disfrutar de su sexualidad de forma plena y responsable.
Published: 2022
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14. Trabajar la igualdad de género en la Educación Infantil desde la formación docente

Author: Patricia Alonso Ruido, Noelia Soto Iglesias, and Alexandre Sotelino Losada
Subjects: educación no sexista, formación, estereotipos de género, igualdad, Educación Infantil, Special aspects of education, LC8-6691, Theory and practice of education, LB5-3640
Abstract: La transmisión del sexismo y de los estereotipos de género que sustentan una realidad de desigualdad de género es una preocupación para la comunidad académica de todos los niveles educativos. Así, el objetivo de este estudio es analizar las percepciones, actitudes y comportamientos en materia de igualdad de género de un grupo de docentes de Educación Infantil. Mediante una metodología cualitativa se han realizado entrevistas en las que participaron 13 docentes del segundo ciclo de Educación Infantil de Galicia, con un rango de edad situado entre los 27 a los 52 años, siendo la media de 36.92 (SD = 8.06). Los resultados evidencian el compromiso docente con la igualdad de género tanto en relación a la formación, como respecto a llevar al aula actuaciones que generen igualdad, la necesidad de reconsiderar los estereotipos de género y promover prácticas igualitarias. Además, a través del discurso de las informantes se evidencia la existencia de situaciones de discriminación, sexismo y transmisión de roles y rasgos estereotipados en la etapa de Educación Infantil. La formación de los/as futuros/as docentes en materia de igualdad de género no es cuestión baladí, sino una necesidad fundamental. En consecuencia, es urgente instalar esta temática en la formación de los/as futuros/as docentes.
Published: 2022
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15. Análisis de la campaña #PrimAcoso: un continuo de violencias sexuales

Author: Yolanda Rodríguez-Castro, Rosana Martínez-Román, Patricia Alonso-Ruido, and María Victoria Carrera-Fernández
Subjects: violencias sexuales, abuso sexual, acoso sexual, agresión sexual, Political science, Social sciences (General), H1-99
Abstract: El objetivo de este estudio es analizar la primera experiencia de violencia sexual que han sufrido las mujeres a través de los tuits de denuncia en la Campaña #PrimAcoso. Durante un mes se identificó un total de 2,887 tuits publicados con el hastag #PrimerAcoso, de los cuales 688 eran tuits y 2,199, retuits. Los resultados muestran que 76% de los tuits aluden a casos de múltiples violencias contra menores de 18 años (65% fueron situaciones de abuso sexual a menores, y 11% acoso sexual entre iguales) y 24% a múltiples violencias contra mujeres adultas (21.3% de acoso sexual, 1.6% de acoso por razón de sexo y 1.1% de agresión sexual). La violencia sexual es una realidad que sufren mayoritariamente las mujeres, y su primera experiencia se ubica en la infancia. Por ello es importante la educación sexual para prevenir ese problema.
Published: 2021
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16. Korevaar-Schoen $p$-energies and their $\Gamma$-limits on Cheeger spaces

Author: Ruiz, Patricia Alonso and Baudoin, Fabrice
Subjects: Mathematics - Functional Analysis, Mathematics - Analysis of PDEs, Mathematics - Metric Geometry, 30L99, 31C45, 46E36, 47H99
Abstract: This paper studies properties of $\Gamma$-limits of Korevaar-Schoen $p$-energies on a Cheeger space. When $p>1$, this kind of limit provides a natural $p$-energy form that can be used to define a $p$-Laplacian, and whose domain is the Newtonian Sobolev space $N^{1,p}$. When $p=1$, the limit can be interpreted as a total variation functional whose domain is the space of BV functions. When the underlying space is compact, the $\Gamma$-convergence of the $p$-energies is improved to Mosco convergence for every $p \ge 1$., Comment: 26 pages
Published: 2024

17. Water Ultrasound-Assisted Extraction of Polyphenol Compounds from Brewer’s Spent Grain: Kinetic Study, Extract Characterization, and Concentration

Author: Patricia Alonso-Riaño, María Teresa Sanz Diez, Beatriz Blanco, Sagrario Beltrán, Ester Trigueros, and Oscar Benito-Román
Subjects: brewer’s spent grains, ultrasound assisted extraction, polyphenol compound, extractives concentration, Therapeutics. Pharmacology, RM1-950
Abstract: Brewer’s spent grain (BSG) was chemically characterized obtaining 52.1% of carbohydrates, 17.8% protein, 5.9% lipids, 13.5% insoluble lignin and 24.3% of water-soluble extractives. This work has been focused on the study of polyphenol extraction of the extractive fraction by water ultrasound-assisted extraction. Selected extraction conditions were 47 °C and 21.7 mL water/gdry-BSG. The effect of solvent polarity on polyphenol extraction was studied by using ethanol aqueous mixtures, from 20% to 100% ethanol. The kinetics of polyphenol extraction have been fitted to the power law and the Weibull models yielding mean values of the root mean square deviation lower than 7.5%. Extracts have been characterized in terms of quantification of individual phenolic compounds by HPLC-DAD and protein and sugar soluble fractions (glucose, xylose, and arabinose). Polyphenol profile has been compared with other hydrolytic techniques, such as acid, basic and enzymatic hydrolysis, showing that ultrasound was not as effective as basic hydrolysis to release the phenolic acids esterified to the cell wall. A further centrifuge ultrafiltration concentration step was able to yield a retentate enriched in the protein fraction while individual phenolic compounds where mainly transferred to the permeate.
Published: 2020
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18. CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation.

Author: Richard Hunte, Patricia Alonso, Remy Thomas, Cassandra Alexandria Bazile, Juan Carlos Ramos, Louise van der Weyden, Juan Dominguez-Bendala, Wasif Noor Khan, and Noula Shembade
Subjects: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
Abstract: Approximately 12% of all human cancers worldwide are caused by infections with oncogenic viruses. Kaposi's sarcoma herpesvirus/human herpesvirus 8 (KSHV/HHV8) is one of the oncogenic viruses responsible for human cancers, including Kaposi's sarcoma (KS), Primary Effusion Lymphoma (PEL), and the lymphoproliferative disorder multicentric Castleman's disease (MCD). Chronic inflammation mediated by KSHV infection plays a decisive role in the development and survival of these cancers. NF-κB, a family of transcription factors regulating inflammation, cell survival, and proliferation, is persistently activated in KSHV-infected cells. The KSHV latent and lytic expressing oncogenes involved in NF-κB activation are vFLIP/K13 and vGPCR, respectively. However, the mechanisms by which NF-κB is activated by vFLIP and vGPCR are poorly understood. In this study, we have found that a host molecule, Cell Adhesion Molecule 1 (CADM1), is robustly upregulated in KSHV-infected PBMCs and KSHV-associated PEL cells. Further investigation determined that both vFLIP and vGPCR interacted with CADM1. The PDZ binding motif localized at the carboxyl terminus of CADM1 is essential for both vGPCR and vFLIP to maintain chronic NF-κB activation. Membrane lipid raft associated CADM1 interaction with vFLIP is critical for the initiation of IKK kinase complex and NF-κB activation in the PEL cells. In addition, CADM1 played essential roles in the survival of KSHV-associated PEL cells. These data indicate that CADM1 plays key roles in the activation of NF-κB pathways during latent and lytic phases of the KSHV life cycle and the survival of KSHV-infected cells.
Published: 2018
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19. Lesiones cutáneas aisladas en un neonato: un caso de histiocitosis de Langerhans congénita

Author: Estíbaliz López-Herce Arteta, Patricia Alonso Rivero, María Itziar Marsinyach Ros, and Minia Campos Domínguez
Subjects: Pediatrics, RJ1-570
Published: 2019
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20. Violencia en las relaciones de pareja de adolescentes gallegos/as

Author: Yolanda Rodríguez-Castro, María Lameiras-Fernández, María Victoria Carrera-Fernández, and Patricia Alonso-Ruido
Subjects: violencia de género, adolescentes, víctimas, Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: El objetivo de este estudio consiste en evaluar la prevalencia de la violencia en las relaciones de pareja de los y las adolescentes desde la perspectiva de la víctima. La muestra formada por 400 estudiantes de Secundaria de Galicia. La edad media fue de 16.29 años. Los resultados muestran bajas tasas de prevalencia en violencia física, sexual y relacional. Pero un alto nivel de violencia verbal sufrida por los y las adolescentes en sus relaciones de pareja. Por lo tanto, la violencia de género también está presente en la vida de los y las adolescentes.
Published: 2017
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21. Las motivaciones hacia el Sexting de los y las adolescentes gallegos/as

Author: Patricia Alonso Ruido, Yolanda Rodríguez Castro, María Lameiras Fernández, and Rosana Martínez Román
Subjects: adolescentes, Sexting, comportamientos, motivaciones, educación., Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: El objetivo de esta investigación es evaluar las motivaciones de los/as adolescentes para llevar a cabo comportamientos de Sexting; así como, analizar su percepción sobre los motivos más frecuentes que la gente de su edad alude para sextear, analizando las diferencias según el género y la localización. Participaron un total de 1286 estudiantes de la Provincia de Ourense, con una media de edad de 15.63 (DT: 1.35). Los resultados apuntan motivos muy diversos y variados, identificando a los chicos como más sexters en relación al envío de textos erótico sexuales.
Published: 2017
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22. Evaluación de las actitudes hacia la diversidad sexual de adolescentes del ámbito semi-rural gallego

Author: Yolanda Rodríguez-Castro and Patricia Alonso-Ruido
Subjects: homofobia, lesbofobia, sexismo, adolescentes, semi-rural, Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: El objetivo de este estudio consiste en analizar las actitudes hacia la diversidad sexual de los y las adolescentes del ámbito semi-rural. Para ello contamos con una muestra de 150 adolescentes del 2º ciclo de la E.S.O, con una media de edad de 15.9. Los resultados muestran que los chicos son más homófobos que las chicas. Destacar que los chicos tienen actitudes más positivas hacia el lesbianismo que hacia la homosexualidad. Los/as chicos/as más sexistas hostiles son los que tienen actitudes más negativas hacia el lesbianismo/homosexualidad. También los/as adolescentes del ámbito semi-rural presentan mayores niveles de homofobia y de sexismo.
Published: 2017
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23. Análisis del Acoso Sexual y por Razón de Sexo desde la perspectiva de Víctima

Author: Rosana Martinez Román, Yolanda Rodríguez-Castro, and Patricia Alonso-Ruido
Subjects: Acoso sexual, acoso en función del sexo, mujer, Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: El objetivo de este estudio consiste analizar las situaciones de Acoso sexual y Acoso en función del sexo que han podido sufrir el estudiantado universitario y cómo se han sentido después de estas situaciones. Han participado en este estudio cualitativo 160 estudiantes. Los principales resultados obtenidos evidencian que más de la mitad del estudiantado han sufrido situaciones de Acoso sexual y Acoso en función del sexo por parte de personas de su entorno. A su vez, los hallazgos también nos permiten visibilizar la magnitud del problema del Acoso sexual que sufren el estudiantado universitario/a.
Published: 2017
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24. El impacto de las Redes Sociales en adolescentes gallegos/as: análisis cualitativo

Author: Patricia Alonso Ruido, Yolanda Rodríguez Castro, and María Lameiras Fernández
Subjects: adolescentes, Redes Sociales, responsabilidad, peligros, educación., Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: El objetivo de esta investigación es evaluar la gestión y percepciones de las Redes Sociales (R.S.) en un grupo de adolescentes de la Provincia de Ourense a través de grupos de discusión. En esta investigación participan 222 estudiantes de Institutos de Educación Secundaria. El análisis del discurso, evidencia que la unanimidad de los/as estudiantes utilizan diariamente las R.S., incluso en algunos casos afirman que de no poder conectarse durante un día sentirían ansiedad. Conjuntamente, se consideran responsables en el uso y gestión que hacen de sus perfiles, a pesar de que afirman tener contacto con personas desconocidas
Published: 2017
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25. URJC GB dataset: Community-based seed bank of Mediterranean high-mountain and semi-arid plant species at Universidad Rey Juan Carlos (Spain)

Author: Patricia Alonso and Jose Maria Iriondo
Subjects: Botany, QK1-989
Abstract: The Germplasm Bank of Universidad Rey Juan Carlos was created in 2008 and currently holds 235 accessions and 96 species. This bank focuses on the conservation of wild-plant communities and aims to conserve ex situ a representative sample of the plant biodiversity present in a habitat, emphasizing priority ecosystems identified by the Habitats Directive. It is also used to store plant material for research and teaching purposes. The collection consists of three subcollections, two representative of typical habitats in the center of the Iberian Peninsula: high-mountain pastures (psicroxerophylous pastures) and semi-arid habitats (gypsophylic steppes), and a third representative of the genus Lupinus. The high-mountain subcollection currently holds 153 accessions (63 species), the semi-arid subcollection has 76 accessions (29 species,) and the Lupinus subcollection has 6 accessions (4 species). All accessions are stored in a freezer at -18 °C in Kilner jars with silica gel. The Germplasm Bank of Universidad Rey Juan Carlos follows a quality control protocol which describes the workflow performed with seeds from seed collection to storage. All collectors are members of research groups with great experience in species identification. Herbarium specimens associated with seed accessions are preserved and 63% of the records have been georreferenced with GPS and radio points. The dataset provides unique information concerning the location of populations of plant species that form part of the psicroxerophylous pastures and gypsophylic steppes of Central Spain as well as populations of genus Lupinus in the Iberian Peninsula. It also provides relevant information concerning mean seed weight and seed germination values under specific incubation conditions. This dataset has already been used by researchers of the Area of Biodiversity and Conservation of URJC as a source of information for the design and implementation of experimental designs in these plant communities. Since they are all active subcollections in continuous growth, data is updated regularly every six months and the latest version can be accessed through the GBIF data portal at http://www.gbif.es:8080/ipt/resource.do?r=germoplasma-urjc. This paper describes the URJC Germplasm Bank and its associated dataset with the aim of disseminating the dataset and explaining how it was derived.
Published: 2014
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26. Explicación del tamaño muestral empleado: una exigencia irracional de las revistas biomédicas Explanation of samples sizes in current biomedical journals: an irrational requirement

Author: Luis Carlos Silva Ayçaguer and Patricia Alonso Galbán
Subjects: Tamaño de muestra, Guía, Ensayo clínico controlado, Estadísticas, Artículo de revista, Sample size, Guidelines, Controlled clinical trial, Statistics, Journal article, Public aspects of medicine, RA1-1270
Abstract: Objetivos: Discutir conceptualmente la pertinencia de las demandas prevalecientes acerca de lo que debe comunicarse sobre la determinación del tamaño de muestra en estudios publicados, y aquilatar el grado en que tales demandas son satisfechas por autores y exigidas por árbitros y editores. Métodos: Se llevó adelante una búsqueda bibliográfica con el fin de conocer y debatir críticamente los razonamientos que pudieran haberse expuesto para respaldar la norma según la cual los autores deben justificar el tamaño muestral. A continuación se valoró el cumplimiento de dicha norma en los artículos originales publicados a lo largo de 2009 en las seis revistas de más alto factor de impacto en el campo de la salud. Resultados: Las razones esgrimidas para respaldar la exigencia de explicar el tamaño muestral empleado resultan escasas y endebles, a la vez que hay no pocas razones para no suscribirlas. Se constató que dicha pauta es mayoritariamente ignorada en la literatura actual de mayor impacto. En el 56% (intervalo de confianza del 95% [IC95%]: 52-59) de los artículos no se fundamenta el tamaño empleado y sólo el 27% (IC95%: 23-30) cumple con todas las exigencias de las guías a las que se adhieren las propias revistas estudiadas. Conclusiones: El estudio permite concluir que no hay argumentos convincentes para exigir que en un artículo publicado se explique cómo se llegó a cierto tamaño muestral. Tal exigencia carece de utilidad y no promueve, sino que más bien menoscaba, la transparencia del reporte de las investigaciones.Objectives: To discuss the theoretical relevance of current requirements for explanations of the sample sizes employed in published studies, and to assess the extent to which these requirements are currently met by authors and demanded by referees and editors. Methods: A literature review was conducted to gain insight into and critically discuss the possible rationale underlying the requirement of justifying sample sizes. A descriptive bibliometric study was then carried out based on the original studies published in the six journals with the highest impact factor in the field of health in 2009. Results: All the arguments used to support the requirement of an explanation of sample sizes are feeble, and there are several reasons why they should not be endorsed. These instructions are neglected in most of the studies published in the current literature with the highest impact factor. In 56% (95%CI: 52-59) of the articles, the sample size used was not substantiated, and only 27% (95%CI: 23-30) met all the requirements contained in the guidelines adhered to by the journals studied. Conclusions: Based on this study, we conclude that there are no convincing arguments justifying the requirement for an explanation of how the sample size was reached in published articles. There is no sound basis for this requirement, which not only does not promote the transparency of research reports but rather contributes to undermining it.
Published: 2013

27. Factores pronósticos relacionados con la supervivencia del cáncer de mama Prognostic factors related to breast cancer survival

Author: Lourdes Flores-Luna, Eduardo Salazar-Martínez, Reyna Margarita Duarte-Torres, Gabriela Torres-Mejía, Patricia Alonso-Ruiz, and Eduardo Lazcano-Ponce
Subjects: supervivencia, cáncer de mama, factores pronósticos, estadio clínico, México, survival, breast cancer, prognostic factors, clinical stage, Mexico, Public aspects of medicine, RA1-1270
Abstract: OBJETIVO: Evaluar los factores pronósticos del cáncer de mama en mujeres mexicanas. MATERIAL Y MÉTODOS: Se incluyó a 432 mujeres con cáncer de mama admitidas de 1990 a 1999 en el Hospital General de México para evaluar la supervivencia mediante las técnicas de Kaplan-Meier y los métodos de riesgos proporcionales de Cox. RESULTADOS: La supervivencia global a cinco años fue de 58.9%. La menor supervivencia corresponde a los estadios clínicos IIIB (47.5%), IIIA (44.2%) y IV(15%), la metástasis hematógena fue de 21.4% y el tumor positivo en bordes quirúrgicos de 12.5%. La invasión linfovascular (RR= 1.9; IC95% 1.3-2.8), el estadio clínico IV (RR= 14.8; IC95% 5.5-39.7) y el tumor en bordes quirúrgicos (RR= 2.4; IC95% 1.2-4.8) fueron los principales factores pronósticos. CONCLUSIONES: Estos resultados dan consistencia a los criterios de diagnóstico y tratamiento de las mujeres con cáncer de mama atendidas en México y toman en consideración las condiciones de la tumoración, como extensión de la malformación, etapa clínica y estado de los ganglios linfáticos antes de decidir la conducta terapéutica inicial.OBJECTIVE: To evaluate prognostic factors for breast cancer in Mexican women. MATERIAL AND METHODS: Four hundred and thirty two women with breast cancer, admitted from 1990 to 1999 to the General Hospital of Mexico, were included to evaluate their survival using the Kaplan-Meier technique and Cox proportional hazard method. RESULTS: Overall 5-year survival was 58.9%. The shortest survival rate corresponds to the clinical stage (IIIB, 47.5%; IIIA, 44.2%; and IV, 15%), the haematological metastasis (21.4%) and surgical edges with positive tumor (12.5%). Lymph node-positive (RR, 1.9; IC95%, 1.3-2.8), clinical stage IV (RR, 14.8; IC95%, 5.5-39.7) and surgical edges with positive tumor (RR, 2.4; IC95%, 1.2-4.8) were the central prognostic factors. CONCLUSIONS: These results give consistency to diagnostic and therapeutic criteria for women with breast cancer who receive medical attention in Mexico, taking into consideration the characteristics of the tumor -such as extension, clinical stage and status of the lymph nodes- before making a decision as to the initial therapy.
Published: 2008

28. Estudio cualitativo en un grupo de estudiantes ourensanos/as sobre el fenómeno del Sexting

Author: Patricia Alonso-Ruido, Yolanda Rodríguez-Castro, and Carmen Pérez-André
Subjects: sexting, comportamientos, motivaciones, educación, Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: El Sexting es el envío, recepción y reenvío de contenidos de tipo sexual o erótico (fotografías, vídeos y/o textos) a otras personas a través de teléfonos móviles, tablets, redes sociales u otros medios informáticos. A nivel internacional es todavía un fenómeno de estudio muy reciente pero de plena actualidad, sin embargo en nuestro país existen escasas investigaciones que se centren en evaluar el fenómeno del sexting. El objetivo de esta investigación consiste en identificar los comportamientos, motivaciones y percepciones de los/las adolescentes de la ciudad de Ourense sobre el Sexting. Este estudio está basado en una metodología cualitativa, se utilizó la técnica de Focus Group. La muestra formada por cuatro Focus Group de estudiantes de ESO y Bachillerato, 23 chicas y 24 chicos, con un rango de edad de 15 a 18 años. Para analizar la información obtenida se utilizó la técnica de análisis de contenido naturalista. Del análisis de sus discursos se destaca que en un principio la tónica general era no admitir enviar contenidos de sexting, posteriormente sí reconocieron enviar fotografías y textos erótico/sexuales afirmando que era “lo lógico” o “de toda la vida”. Algunos/as de los/as adolescentes relataban difundir contenidos como fotos contra el espejo sin camiseta, en ropa de baño o vestidos/as pero con actitudes eróticas, no obstante no incluían estos comportamientos dentro del fenómeno de sexting. Por otro lado en referencia a la recepción de fotografías erótico/sexuales de otras personas prácticamente la totalidad de los/as adolescentes respondían que sí recibían este tipo de contenidos con mucha frecuencia, tanto de personas conocidas como desconocidas, alegando que “en España hay montones” y que son fundamentalmente chicas “posando desnudas” o “no salen desnudas ni nada pero las posturas un poco pervertidas”. Incluso refieren casos cercanos de chicas “conocidas o conocidas de vista” y “hubo un caso de esta clase”, no obstante afirman eliminar este tipo de contenidos que reciben. En su mayoría aseveran que las personas de su edad se hacen fotografías erótico/sexuales y las difunden, afirmando que “mucha gente” y “en Instagram hay de todo” o “aquí en España sí”. En referencia a las motivaciones para practicar sexting aludían causas como aburrimiento, fama, mostrar su cuerpo, presumir, excitar a la persona destinataria, por estar de moda, iniciar relaciones afectivo-sexuales, no ser conscientes de las consecuencias e incluso en relación a vídeos eróticos/sexuales “para verse después” y “para ver los fallos en el acto sexual”. En conclusión se manifiesta la necesidad de formar y concienciar sobre el sexting a los/las adolescentes educando en la prevención de los riesgos que la práctica de sexting tiene asociados, pero también al conjunto de profesionales, docentes y familias para así ofrecer la adecuada respuesta psicosocioeducativa.
Published: 2015
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29. Hábitos de uso en las Redes Sociales de los y las adolescentes: análisis de género

Author: Patricia Alonso-Ruido, Yolanda Rodríguez-Castro, María Lameiras-Fernández, and María Victoria Carrera-Fernández
Subjects: redes sociales, hábitos, uso, formación, Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: El impacto provocado por la generalización de las Redes Sociales ha supuesto drásticas transformaciones en las formas de comunicación y socialización. Esta realidad no deja al margen a los/las adolescentes, verdaderos/as nativos/as digitales. El objetivo de este estudio consiste en conocer los hábitos de uso en las Redes Sociales de los/as estudiantes ourensanos/as analizando las diferencias de género. La muestra estaba formada por 1283 estudiantes de la provincia de Ourense con una media de edad de 15,55 (DT: 1,6). Entre las conclusiones más relevantes se destaca que las R.S. son utilizadas tanto por chicos como por chicas con asiduidad. La mayor parte de los/as adolescentes refieren tener perfiles en una o más R.S. (siendo Facebook, Twitter y Tuenti las más utilizadas), a las que acceden fundamentalmente a través de su móvil (Chi2= 5,86; p
Published: 2015
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30. Análisis de los discursos de los y las jóvenes sobre la violencia en las relaciones de pareja

Author: Yolanda Rodríguez-Castro and Patricia Alonso-Ruido
Subjects: violencia de género, adolescentes, pareja, Special aspects of education, LC8-6691, Psychology, BF1-990
Abstract: La violencia en las relaciones de pareja es actualmente uno de los problemas sociales serios con los que se enfrenta esta sociedad. La gravedad de esta problemática se intensifica a la luz de los datos que configuran que la violencia que se ejerce en las primeras relaciones de pareja entre adolescentes, comienzan cada vez a una edad más temprana, situando los primeros episodios violentos entre 11 y 17 años. Esta violencia en las relaciones de pareja abarca tanto aquellas que se producen en parejas que llevan juntas mucho tiempo como en parejas que están empezando su relación de noviazgo. La mayoría de los estudios de violencia en las relaciones de pareja de los/as adolescentes son de corte cuantitativo y se centran en determinar la prevalencia del problema. El objetivo de nuestro estudio basado en una metodología cualitativa, consiste en analizar la violencia en las relaciones de pareja de los/as adolescentes a través de sus propios discursos a través de grupos de discusión. Para ello, se llevó a cabo un total de cuatro grupos de discusión, dos en el segundo ciclo de la Educación Secundaria Obligatoria y otros dos en Bachillerato en un Instituto de Educación Secundaria de la ciudad de Ourense. En total participaron 40 estudiantes con edades comprendidas entre 15 y 18 años, de los cuales 21 son chicos y 19 son chicas. Todos/as los/as adolescentes de la muestra accedieron a participar de forma voluntaria en el estudio tras previa comunicación a los padres/madres por parte del tutor o jefe de estudios. En el grupo de discusión se les plantearon cuestiones relativa a qué significa una relación de pareja, que entendían por violencia en las relaciones de pareja o noviazgo entre adolescentes, si conocían algún amigo/a que sufriera este tipo de violencia de pareja, se les preguntó también sobre cuales creían que eran las razones por las que se puede actuar con violencia hacia la parece. Los resultados nos evidencian que chicos y chicas muestran percepciones de las relaciones de pareja, las chicas siguen mostrando en sus discursos visiones más románticas del amor, y siguen considerando los celos como una muestra de amor. En cuanto a la violencia ejercida en las parejas de adolescentes, son muchas chicas las que afirman conocer distintos casos de amigas que sufren violencia física leve y violencia psicológica/verbal. También los chicos manifiestan conocer casos de violencia verbal por parte de sus parejas femeninas. En cuanto a las razones que señalan para que algunos/as actúen con violencia hacia sus parejas, son principalmente los celos y el consumo excesivo de alcohol u otras drogas. Destacar que un par de chicas manifestaron que cuando una chica “insulta” a su pareja es para defenderse de los ataques de su pareja. Por lo tanto, estos resultados evidencian que la violencia de género también está presente en la vida de los/as adolescentes, con lo cual es importante trabajar con este colectivo desde una perspectiva coeducativa que fomente el buen trato y una educación sin violencia.
Published: 2015
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31. Recommendations for cervical cancer screening programs in developing countries: the need for equity and technological development Recomendaciones a programas de detección oportuna de cáncer cervical en países en desarrollo: necesidad de equidad y desarrollo tecnológico

Author: Eduardo Lazcano-Ponce, Patricia Alonso, José Antonio Ruiz-Moreno, and Mauricio Hernández-Avila
Subjects: cáncer cervical, países en desarrollo, detección oportuna de cáncer, citología cervical, colposcopia, VPH, vacunas, cervical cancer, developing countries, screening, cervical cytology, colposcopy, HPV, vaccine, Public aspects of medicine, RA1-1270
Abstract: The cervical cancer screening programs (CCSP) have not been very efficient in the developing countries. This explains the need to foster changes on policies, standards, quality control mechanisms, evaluation and integration of new screening alternatives considered as low and high cost, as well as to regulate colposcopy practices and the foundation of HPV laboratories. Cervical cancer (CC) is a disease most frequently found in poverty-stricken communities and reflecting a problem of equity at both levels gender and regional, and this, is not only due to social and economic development inequalities, but to the infrastructure and human resources necessary for primary care. For this reason, the CCSP program must be restructured, a) to primarily address unprivileged rural and urban areas; b) to foster actions aimed at ensuring extensive coverage as well as a similar quality of that coverage in every region; c) to use screening strategies in keeping with the availability of health care services. In countries with a great regional heterogeneity, a variety of screening procedures must be regulated and standardized, including a combination of assisted visual inspection, cervical cytology and HPV detection; d) regional community intervention must be set up to assess the effectiveness of using HPV detection as an strategy in addition to cervical cytology (pap smear); e) the practice of colposcopy must be regulated to prevent the use of it in healthy women at a population level, thus preventing unnecessary diagnosis and treatment which not only are expensive but also causes unnecessary anxiety to women at risk; f) the operation of those clinical laboratories using HPV as a detection strategy must likewise be accredited and regulated and g) the CCSP program for assuring health care quality should meet the expectations of its beneficiaries, and increase the knowledge in cervical cancer related matters. Finally, though a variety of clinical tests on prophylactic and therapeutic vaccines against HPV are recently being developed worldwide; it will take at least from 5 to 10-years time to have them available in the market. For this reason, it will be necessary to intensify the CCSP programs. All these reasons lay emphasis on the need to reinforce actions for CCSP programs.Los programas poblacionales de detección oportuna de cáncer cervical (DOC) han sido poco eficientes en países en desarrollo. Por esta razón, es necesario impulsar cambios en las políticas, normatividad, mecanismos de control de calidad, evaluación e integración de nuevas alternativas de tamizaje consideradas de bajo y alto costo, así como la regulación de la práctica de colposcopía y de la futura integración de laboratorios para el VPH. El cáncer cervicouterino (CC) es una enfermedad de la pobreza que refleja un problema de equidad de género y de equidad regional, no sólo en cuanto a diferencias de desarrollo económico y social, sino en cuanto a la infraestructura física y de recursos humanos que otorgan servicios de atención primaria. Por esta razón, un programa de DOC debe reorganizarse para: a) dirigirse predominantemente a regiones geográficas rurales y urbanas marginadas, b) impulsar acciones que garanticen una cobertura ampliada y calidad similar en todas las regiones, c) utilizar estrategias de tamizaje acordes con la disponibilidad de servicios de atención médica. En países con gran heterogeneidad regional deben regularse y normarse diversos escenarios de tamizaje que incluyan la combinación de imagen visual asistida, citología cervical y determinación del VPH, d) se deben iniciar intervenciones comunitarias regionales que evalúen la efectividad de utilizar el VPH como estrategia adicional a la citología cervical (Pap), e) se debe regular la práctica de la colposcopía para evitar su utilización en mujeres sanas a nivel poblacional, y así, evitar sobre-diagnóstico y sobre-tratamiento, que no sólo tienen implicaciones de elevados costos, sino que producen ansiedad innecesaria en las mujeres en riesgo, f) debe acreditarse y regularse la práctica de los laboratorios clínicos que determinen el VPH como estrategia de detección, y g) el programa de DOC para garantizar calidad, también deberá satisfacer las expectativas de las usuarias, así como aumentar el conocimiento sobre cáncer cervical. Finalmente, a pesar de que diversos ensayos clínicos de vacunas profilácticas y terapéuticas contra el VPH se desarrollan actualmente a nivel mundial al menos durante un periodo de entre 5 y 10 años las vacunas contra este virus no estarán disponibles comercialmente. Por esta razón, será necesario reforzar las acciones de los programas de DOC.
Published: 2003

32. El conocimiento de profesionales de la salud sobre la prevención del cáncer cervical. Alternativas de educación médica Knowledge of healthcare professionals on cervical cancer prevention. Alternatives for medical education

Author: Edna Arillo-Santillán, Eduardo Lazcano-Ponce, Merce Peris, Eduardo Salazar-Martínez, Jorge Salmerón-Castro, and Patricia Alonso-De Ruiz
Subjects: personal de salud, neoplasmas del cuello uterino, amizaje masivo, educación continua, México, health personnel, cervix neoplasms, mass screening, education, continuing, Mexico, Public aspects of medicine, RA1-1270
Abstract: OBJETIVO: Evaluar el nivel de conocimientos que diversos tipos de profesionales de la salud tienen sobre la prevención del cáncer cervical. MATERIAL Y MÉTODOS: Se realizó un estudio transversal entre 520 profesionales de la salud del estado de Morelos durante 1998, para evaluar y cuantificar el nivel de conocimientos que poseen en relación con el impacto, la etiología, el tamizaje, el diagnóstico y el tratamiento del cáncer cervicouterino. Se aplicó un cuestionario con escala de 1 a 10, y la muestra incluyó a especialistas en medicina familiar, especialistas de áreas clínicas, enfermeras especialistas y generales, así como trabajadoras sociales. El análisis estadístico incluyó análisis de varianza y estimación de intervalos de confianza al 95%. RESULTADOS: La media del nivel de conocimiento acerca de la prevención del cáncer cervicouterino fue de 4.74, con un intervalo de confianza (IC) al 95% de 4.57-4.88, en una escala máxima de 10. La mayor diferencia en el índice de conocimiento acerca de el diagnóstico, la prevención y el tratamiento del cáncer cervical se observó entre los médicos de especialidades clínicas ( o = 5.21, IC95% 4.81-5.60), en comparación con las trabajadoras sociales ( o = 3.07, IC95% 2.31-3.82). En la mayoría de los casos, la periodicidad con la que una mujer debe hacerse la prueba de Papanicolaou se postula menor a un año, y existe un pobre consenso en relación con el periodo de edad en que debe obtenerse dicha prueba. El nivel de conocimientos es menor conforme se tratan de identificar aspectos etiológicos y perspectivas de tratamiento. CONCLUSIONES: La educación médica continua es necesaria para el desarrollo óptimo de un programa de detección oportuna de cáncer cervical. Los resultados del estudio en el estado de Morelos revelan que, además de mejorar los programas académicos de formación de pregrado, es necesario incrementar las intervenciones educativas entre los profesionales de la salud. Para ello, se contemplan diversas estrategias, entre las que destacan la actualización, el reciclaje, la capacitación, la educación en salud y la educación médica continua. De esta forma se podrá promover la competencia profesional para incrementar la calidad de la atención médica.OBJECTIVE: Several studies have shown the importance of health care professionals as predictors of the use of cervical cancer screening (CCS). MATERIAL AND METHODS: A cross- sectional study of 520 health care professionals in the State of Morelos during 1998, in order to evaluate and quantify their level of knowledge on the impact, etiology, screening, diagnosis and treatment of cervical cancer. A 1 to 10 scale questionnaire was given, and the sample included family medicine specialists, general practitioners, specialist and general nurses, and social workers. Statistical analysis included analysis of variance and 95% confidence intervals. RESULTS: A knowledge mean of 4.74 (95% CI 4.57-4.88) was observed for a scale of 10; specialist physicians scored higher (mean 5.21, 95% CI 4.81-5.60) than social workers (mean 3.07, 95% CI 2.31-3.82). Periodicity of the Pap test in most cases was less than 1 year and there was poor consensus about the age period during which the Pap test should be obtained. The knowledge level was lower when trying to identify etiologic aspects and treatment perspectives. CONCLUSIONS: The results of this study show that, besides the improvement of undergraduate academic programs, it is necessary to improve educational interventions for health care professionals through the updating, recycling, training, health education, and continuing medical education, among others, to promote professional competence and thus improve the quality of medical care.
Published: 2000

33. Factores que determinan la participación en el tamizaje de cáncer cervical en el estado de Morelos Factors which determine participation in an early detection program of cervical cancer in the state of Morelos

Author: Eduardo César Lazcano-Ponce, Sue Moss, Aurelio Cruz-Valdez, Patricia Alonso de Ruiz, Salvador Casares-Queralt, and Carlos Javier Martínez-León
Subjects: neoplasmas del cuello uterino, detección oportuna de cáncer, México, cervix neoplasms, early cancer detection, Mexico, Public aspects of medicine, RA1-1270
Abstract: OBJECTIVO. Determinar los principales factores relacionados con la participación en un programa de detección oportuna de cáncer (DOC) en una población con elevada mortalidad por cáncer cervical (CACU). MATERIAL Y MÉTODOS. En el estado de Morelos se desarrolló un estudio con base poblacional que incluyó 3 197 mujeres de entre 15 y 49 años de edad, seleccionadas aleatoriamente de un marco muestral de viviendas de los 33 municipios que componen dicha entidad. RESULTADOS. El conocimiento de la utilidad de la prueba de Papanicolaou (Pap) (RM 29.6, IC95% 23.6-37) y la historia previa de síntomas ginecológicos (RM 1.7; IC95% 1.2-2.4) predisponen a utilizar el programa de DOC. Los factores asociados a la utilización de la prueba de Pap fueron que las mujeres tuvieran antecedentes en la utilización de uno (RM 1.4; IC95% 1.1-1.8), dos o más métodos de planificación familiar (RM 2.1; IC95% 1.6-2.8). CONCLUSIONES. En el estado de Morelos, México, el tamizaje en CACU se ofrece predominantemente en forma oportunista, por lo que el antecedente de utilización de los servicios de salud constituye el principal determinante para la utilización del programa de DOC. Estos resultados revelan la necesidad de establecer estrategias alternativas para integrar a las mujeres que no tienen acceso a dichos servicios de atención médica, ya que constituyen el grupo de más alto riesgo para contraer CACU.OBJECTIVE. To determine the main factors associated to participation in an early detection program of cancer (DPC), in a population with a high cervical cancer (CC) mortality rate. MATERIAL AND METHODS. A population-based, cross-sectional study was performed in the state of Morelos, which included 3 197 women aged between 15 and 49 years, randomly selected from a household sample frame of the 33 municipalities of the state. RESULTS. Awareness of the utility of the Papanicolau (Pap) test (OR29.6, 95% CI 23.6-37) and a former history of gynecological symptoms (OR1.7, 95% CI 1.2-2.4) predisposed to greater use of the DPC. Factors associated to the use of the Pap test were precedents of using one contraceptive (OR1.4, 95% CI 1.1-1.8) or two or more contraceptives (OR2.1, 95% CI 1.6-2.8). CONCLUSIONS. In the sate of Morelos, Mexico, screening for cervical cancer is offered opportunistically in the context of health care use. Therefore, the precedent of using health care services is the main determining factor for use of the DPC program. These results reveal the need to design alternative strategies to promote participation among women who have no access to health services, since they constitute the population group at highest risk of developing CC.
Published: 1999

34. Análisis costo beneficio del Programa de Detección Oportuna del Cáncer Cervicouterino Cost benefit analysis of the Cervical Cancer Screening Program

Author: PATRICIA HERNÁNDEZ-PEÑA, EDUARDO CÉSAR LAZCANO-PONCE, PATRICIA ALONSO-DE RUIZ, AURELIO CRUZ-VALDEZ, FERNANDO MENESES-GONZÁLEZ, and MAURICIO HERNÁNDEZ-AVILA
Subjects: neoplamas del cuello uterino, citodiagnóstico, servicios de salud de las mujeres, análisis de costo beneficio, control de calidad, tamizaje, screening, cervix neoplasms, citodiagnosis, women´s health services, cost-benefit analysis, quality control, Public aspects of medicine, RA1-1270
Abstract: Objetivo. Determinar el costo beneficio de la reorganización del Programa de Detección Oportuna del Cáncer Cervicouterino (PDOC) mediante intervenciones de garantía de calidad. Material y métodos. Se siguieron tres etapas: a) identificación y cuantificación de costos; b) identificación y cuantificación de beneficios, y c) evaluación económica del costo beneficio. Resultados. El costo unitario de operación por citología -obtención, fijación, el traslado al centro de lectura, su tinción e interpretación y la notificación de resultados- se estimó en USD$ 11.6. En conjunto, las intervenciones en calidad al PDOC elevarían el costo de cada citología en 32.7%. Sin embargo, la nueva organización generaría una razón beneficio/costo de 2 y un beneficio neto de 88 millones de dólares para los próximos cinco años. Conclusiones. La operación del programa propuesto resulta socialmente deseable, siempre y cuando las modificaciones se lleven a cabo, particularmente la capacitación, la notificación personalizada de los casos positivos, el incremento de cobertura, la introducción de mecanismos de control de calidad, el monitoreo contínuo y el tratamiento en mujeres con anormalidades detectadas.Objective. Previous researches pointed out the critical changes needed to increase the efficiency of the National Screening Programme of Cervical Cancer in Mexico. These changes were assessed through a cost-benefit analysis. This paper presents the results of that appraisal. Figures are presented as USDollars of 1996 valued as 7.5 pesos for each dollar. Results. The operational unitary cost of the integral process of the cytology the obtention of the Pap smear, its transportation to the interpretation centre, its analysis, and the notification of results to users was estimated in US$ 11.6. If the proposed changes are operated, the cost of each citology would increase by 32.7%. The benefit/cost ratio would be 2 and the net benefit of 88 millions of US dollars for the next five years. Conclusions. The operation of the proposed changes is socially desirable, but should be supported the training activities of the personnel, the increase of the coverage of women at risk, the quality control activities, the monitoring of the program and the communication with women detected as positive cases.
Published: 1997

35. Mitosis is a source of potential markers for screening and survival and therapeutic targets in cervical cancer.

Author: Ana María Espinosa, Ana Alfaro, Edgar Roman-Basaure, Mariano Guardado-Estrada, Ícela Palma, Cyntia Serralde, Ingrid Medina, Eligia Juárez, Miriam Bermúdez, Edna Márquez, Manuel Borges-Ibáñez, Sergio Muñoz-Cortez, Avissai Alcántara-Vázquez, Patricia Alonso, José Curiel-Valdez, Susana Kofman, Nicolas Villegas, and Jaime Berumen
Subjects: Medicine, Science
Abstract: The effect of preventive human papillomavirus (HPV) vaccination on the reduction of the cervical cancer (CC) burden will not be known for 30 years. Therefore, it's still necessary to improve the procedures for CC screening and treatment. The objective of this study was to identify and characterize cellular targets that could be considered potential markers for screening or therapeutic targets. A pyramidal strategy was used. Initially the expression of 8,638 genes was compared between 43 HPV16-positive CCs and 12 healthy cervical epitheliums using microarrays. A total of 997 genes were deregulated, and 21 genes that showed the greatest deregulation were validated using qRT-PCR. The 6 most upregulated genes (CCNB2, CDC20, PRC1, SYCP2, NUSAP1, CDKN3) belong to the mitosis pathway. They were further explored in 29 low-grade cervical intraepithelial neoplasias (CIN1) and 21 high-grade CIN (CIN2/3) to investigate whether they could differentiate CC and CIN2/3 (CIN2+) from CIN1 and controls. CCNB2, PRC1, and SYCP2 were mostly associated with CC and CDC20, NUSAP1, and CDKN3 were also associated with CIN2/3. The sensitivity and specificity of CDKN3 and NUSAP1 to detect CIN2+ was approximately 90%. The proteins encoded by all 6 genes were shown upregulated in CC by immunohistochemistry. The association of these markers with survival was investigated in 42 CC patients followed up for at least 42 months. Only CDKN3 was associated with poor survival and it was independent from clinical stage (HR = 5.9, 95%CI = 1.4-23.8, p = 0.01). CDKN3 and NUSAP1 may be potential targets for the development of screening methods. Nevertheless, further studies with larger samples are needed to define the optimal sensitivity and specificity. Inhibition of mitosis is a well-known strategy to combat cancers. Therefore, CDKN3 may be not only a screening and survival marker but a potential therapeutic target in CC. However, whether it's indispensable for tumor growth remains to be demonstrated.
Published: 2013
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36. Correction: Mitosis Is a Source of Potential Markers for Screening and Survival and Therapeutic Targets in Cervical Cancer.

Author: Ana María Espinosa, Ana Alfaro, Edgar Roman-Basaure, Mariano Guardado-Estrada, Ícela Palma, Cyntia Serralde, Ingrid Medina, Eligia Juárez, Miriam Bermúdez, Edna Márquez, Manuel Borges-Ibáñez, Sergio Muñoz-Cortez, Avissai Alcántara-Vázquez, Patricia Alonso, José Curiel-Valdez, Susana Kofman, Nicolas Villegas, and Jaime Berumen
Subjects: Medicine, Science
Published: 2013
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37. Oscillations of BV measures on nested fractals

Author: Ruiz, Patricia Alonso and Baudoin, Fabrice
Subjects: Mathematics - Metric Geometry, Mathematics - Probability, 26A45, 31E05, 31C25, 28A80
Abstract: Motivated by recent developments in the theory of bounded variation functions on nested fractals, this paper studies the exact asymptotics of functionals related to the total variation measure associated with unions of $n$-complexes. The oscillatory behavior observed implies the non-uniqueness of BV measures in this setting., Comment: 16 pages
Published: 2022

38. The cost of open access: comparing public projects' budgets and article processing charges expenditure.

Author: Patricia Alonso-álvarez, Pablo Sastrón-Toledo, and Jorge Mañana-Rodríguez
Published: 2024
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39. Compliance with open access mandates and its effects on research visibility: the case of the Spanish National Plan of R&D.

Author: Pablo Sastrón-Toledo, Patricia Alonso-álvarez, and Jorge Mañana-Rodríguez
Published: 2024
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40. Minimal gap in the spectrum of the Sierpinski gasket

Author: Ruiz, Patricia Alonso
Subjects: Mathematics - Spectral Theory, Mathematics - Functional Analysis, 58J50, 28A80
Abstract: This paper studies the size of the minimal gap between any two consecutive eigenvalues in the Dirichlet and in the Neumann spectrum of the standard Laplace operator on the Sierpinski gasket. The main result shows the remarkable fact that this minimal gap is achieved and coincides with the spectral gap. The Dirichlet case is more challenging and requires some key observations in the behavior of the dynamical system that describes the spectrum., Comment: 14 pages
Published: 2021

41. Yet another heat semigroup characterization of BV functions on Riemannian manifolds

Author: Ruiz, Patricia Alonso and Baudoin, Fabrice
Subjects: Mathematics - Functional Analysis, Mathematics - Analysis of PDEs, Mathematics - Probability
Abstract: This paper provides a characterization of functions of bounded variation (BV) in a compact Riemannian manifold in terms of the short time behavior of the heat semigroup. In particular, the main result proves that the total variation of a function equals the limit characterizing the space BV. The proof is carried out following two fully independent approaches, a probabilistic and an analytic one. Each method presents different advantages.
Published: 2020

42. From Strichartz Estimates to Differential Equations on Fractals

Author: Ruiz, Patricia Alonso, Hinz, Michael, Okoudjou, Kasso A., Rogers, Luke G., Teplyaev, Alexander, Benedetto, John J., Series Editor, Czaja, Wojciech, Series Editor, Okoudjou, Kasso, Series Editor, Aldroubi, Akram, Editorial Board Member, Casazza, Peter, Editorial Board Member, Cochran, Douglas, Editorial Board Member, Feichtinger, Hans G., Editorial Board Member, Gilbert, Anna C., Editorial Board Member, Heil, Christopher, Editorial Board Member, Jaffard, Stéphane, Editorial Board Member, Kutyniok, Gitta, Editorial Board Member, Maggioni, Mauro, Editorial Board Member, Molter, Ursula, Editorial Board Member, Shen, Zuowei, Editorial Board Member, Strohmer, Thomas, Editorial Board Member, Unser, Michael, Editorial Board Member, Wang, Yang, Editorial Board Member, Alonso Ruiz, Patricia, editor, Hinz, Michael, editor, Okoudjou, Kasso A., editor, Rogers, Luke G., editor, and Teplyaev, Alexander, editor
Published: 2023
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43. Cervical cancer: new perspectives for diagnosis, prevention and control in developing countries

Author: Eduardo Lazcano-Ponce, Patricia Alonso de Ruiz, and Mauricio Hernández-Avila
Subjects: Public aspects of medicine, RA1-1270
Published: 2003

44. Coverage and metadata availability of African publications in OpenAlex: A comparative analysis.

Author: Patricia Alonso-álvarez and Nees Jan van Eck
Published: 2024
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45. La comunicación en medicina familiar The communication in family medicine

Author: Félix J. Sansó Soberats, María del Carmen Aguilera Hidalgo, Patricia Alonso Galbán, and Ivonne Torrente Pons
Subjects: Comunicación, medicina familiar, atención primaria de salud, comunidad, Communication, family medicine, primary health care, community, Medicine (General), R5-920
Abstract: En la práctica de la Medicina Familiar la comunicación entre los profesionales y las personas bajo su atención, tiene lugar en diferentes contextos que la singularizan y la hacen más compleja que en cualquier otra especialidad médica. En el presente trabajo se exponen postulados generales sobre la comunicación humana y sus características en el trabajo del Equipo Básico de Salud en el nivel primario de atención médica. Se describen algunos canales de comunicación no verbal y se analizan en su expresión en el contexto del trabajo por la salud comunitaria.In the practice of Family Medicine, the communication between the professionals and the persons receiving their attention takes place in different contexts that make it singular and more complex than in any other specialty. In this paper, the general postulates on human communication and its characteristics in the work of the Basic Health Team at the primary health care level are exposed. Some channels of non-verbal communication are described, and their expression in the context of the community health work is analyzed.
Published: 2006

46. Gagliardo-Nirenberg, Trudinger-Moser and Morrey inequalities on Dirichlet spaces

Author: Ruiz, Patricia Alonso and Baudoin, Fabrice
Subjects: Mathematics - Functional Analysis, Mathematics - Analysis of PDEs, Mathematics - Metric Geometry, Mathematics - Probability, 31C25, 46E35, 31E05, 28A80
Abstract: With a view towards Riemannian or sub-Riemannian manifolds, RCD metric spaces and specially fractals, this paper makes a step further in the development of a theory of heat semigroup based $(1,p)$ Sobolev spaces in the general framework of Dirichlet spaces. Under suitable assumptions that are verified in a variety of settings, the tools developed by D. Bakry, T. Coulhon, M. Ledoux and L. Saloff-Coste in the paper "Sobolev inequalities in disguise" allow us to obtain the whole family of Gagliardo-Nirenberg and Trudinger-Moser inequalities with optimal exponents. The latter depend not only on the Hausdorff and walk dimensions of the space but also on other invariants. In addition, we prove Morrey type inequalities and apply them to study the infimum of the exponents that ensure continuity of Sobolev functions. The results are illustrated for fractals using the Vicsek set, whereas several conjectures are made for nested fractals and the Sierpinski carpet., Comment: 39 pages
Published: 2020

47. BV functions and fractional Laplacians on Dirichlet spaces

Author: Ruiz, Patricia Alonso, Baudoin, Fabrice, Chen, Li, Rogers, Luke, Shanmugalingam, Nageswari, and Teplyaev, Alexander
Subjects: Mathematics - Metric Geometry, Mathematical Physics, Mathematics - Functional Analysis, Mathematics - Probability, 31C25, 46E35, 26A45, 60J45, 28A80
Abstract: We study $L^p$ Besov critical exponents and isoperimetric and Sobolev inequalities associated with fractional Laplacians on metric measure spaces. The main tool is the theory of heat semigroup based Besov classes in Dirichlet spaces that was introduced by the authors in previous works., Comment: Natural ovelap in the framework section (2.1) which has been previously introduced by the authors in arXiv:1903.10078
Published: 2019

48. Heat kernel analysis on diamond fractals

Author: Ruiz, Patricia Alonso
Subjects: Mathematics - Probability, Mathematics - Functional Analysis, 35K08, 60J60, 60J45, 31C25, 28A80
Abstract: This paper presents a detailed analysis of the heat kernel on an $(\mathbb{N}\times\mathbb{N})$-parameter family of compact metric measure spaces, which do not satisfy the volume doubling property. In particular, uniform bounds of the heat kernel and its Lipschitz continuity, as well as the continuity of the corresponding heat semigroup are studied; a specific example is presented revealing a logarithmic correction. The estimates are further applied to derive several functional inequalities of interest in describing the convergence to equilibrium of the diffusion process., Comment: 25 pages, revised
Published: 2019

49. Analysis on hybrid fractals

Author: Ruiz, Patricia Alonso, Chen, Yuming, Gu, Haotian, Strichartz, Robert S., and Zhou, Zirui
Subjects: Mathematics - Functional Analysis, Mathematics - Spectral Theory, 28A80, 31C25, 31C20
Abstract: We introduce hybrid fractals as a class of fractals constructed by gluing several fractal pieces in a specific manner and study energy forms and Laplacians on them. We consider in particular a hybrid based on the $3$-level Sierpinski gasket, for which we construct explicitly an energy form with the property that it does not "capture" the $3$-level Sierpinski gasket structure. This characteristic type of energy forms that "miss" parts of the structure of the underlying space are investigated in the more general framework of finitely ramified cell structures. The spectrum of the associated Laplacian and its asymptotic behavior in two different hybrids is analyzed theoretically and numerically. A website with further numerical data analysis is available at http://www.math.cornell.edu/~harry970804/., Comment: 41 pages, 25 figures, 4 tables
Published: 2018

50. Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries

Author: Glasbey, James C, Abbott, Tom EF, Ademuyiwa, Adesoji, Adisa, Adewale, AlAmeer, Ehab, Alshryda, Sattar, Arnaud, Alexis P, Bankhead-Kendall, Brittany, Abou Chaar, M K, Chaudhry, Daoud, Costas-Chavarri, Ainhoa, Cunha, Miguel F, Davies, Justine I, Desai, Anant, Elhadi, Muhammed, Fiore, Marco, Fitzgerald, James Edward, Fourtounas, Maria, Fowler, Alex James, Futaba, Kay, Gallo, Gaetano, Ghosh, Dhruva, Gujjuri, Rohan R, Hamilton, Rebecca, Haque, Parvez, Harrison, Ewen M, Hutchinson, Peter, Hyman, Gabriella, Isik, Arda, Jayarajah, Umesh, Kaafarani, Haytham MA, Kadir, Bryar, Lawani, Ismail, Lederhuber, Hans, Li, Elizabeth, Löffler, Markus W, Lorena, Maria Aguilera, Mann, Harvinder, Martin, Janet, Mazingi, Dennis, McClain, Craig D, McLean, Kenneth A, Meara, John G, Ramos-De La Medina, Antonio, Mengesha, Mengistu, Minaya, Ana, Modolo, Maria Marta, Moore, Rachel, Morton, Dion, Nepogodiev, Dmitri, Ntirenganya, Faustin, Pata, Francesco, Pearse, Rupert, Picciochi, Maria, Pinkney, Thomas, Pockney, Peter, van Ramshorst, Gabrielle H, Richards, Toby, Roslani, April Camilla, Satoi, Sohei, Sayyed, Raza, Shaw, Richard, Simões, Joana FF, Smart, Neil, Sullivan, Richard, Sund, Malin, Sundar, Sudha, Tabiri, Stephen, Taylor, Elliott H, Venn, Mary L, Wickramasinghe, Dakshitha, Wright, Naomi, Yip, Sebastian Bernardo Shu, Bhangu, Aneel, Omar, Omar, Harrison, Ewen, Bhangu, Aneel A, Siaw-Acheampong, Kwabena, Benson, Ruth A, Bywater, Edward, Dawson, Brett E, Evans, Jonathan P, Heritage, Emily, Jones, Conor S, Kamarajah, Sivesh K, Khatri, Chetan, Khaw, Rachel A, Keatley, James M, Knight, Andrew, Lawday, Samuel, Mann, Harvinder S, Marson, Ella J, Mckay, Siobhan C, Mills, Emily C, Pellino, Gianluca, Tiwari, Abhinav, Trout, Isobel M, Wilkin, Richard JW, Abukhalaf, Sadi, Adamina, Michel, Ademuyiwa, Adesoji O, Agarwal, Arnav, Akkulak, Murat, Alameer, Ehab, Alderson, Derek, Alakaloko, Felix, Albertsmeier, Markus, Alser, Osaid, Alshaar, Muhammad, Augestad, Knut Magne, Ayasra, Faris, Azevedo, José, Bankhead-Kendall, Brittany K, Barlow, Emma, Beard, David, Blanco-Colino, Ruth, Brar, Amanpreet, Minaya-Bravo, Ana, Breen, Kerry A, Bretherton, Chris, Buarque, Igor Lima, Burke, Joshua, Caruana, Edward J, Chaar, Mohammad, Chakrabortee, Sohini, Christensen, Peter, Cox, Daniel, Cukier, Moises, Davidson, Giana H, Di Saverio, Salomone, Drake, Thomas M, Edwards, John G, Emile, Sameh, Farik, Shebani, Ford, Samuel, Garmanova, Tatiana, Gomes, Gustavo Mendonça Ataíde, Grecinos, Gustavo, Griffiths, Ewen A, Gruendl, Magdalena, Halkias, Constantine, Hisham, Intisar, Hutchinson, Peter J, Hwang, Shelley, Jenkinson, Michael D, Jonker, Pascal, Keller, Debby, Kolias, Angelos, Kruijff, Schelto, Leventoglu, Sezai, Litvin, Andrey, Loehrer, Andrew, Major, Piotr, Mashbari, Hassan N, Metallidis, Symeon, Mohan, Helen M, Moszkowicz, David, Moug, Susan, Ng-Kamstra, Joshua S, Maimbo, Mayaba, Negoi, Ionut, Niquen, Milagros, Olivos, Maricarmen, Oussama, Kacimi, Outani, Oumaima, Parreno-Sacdalanm, Marie Dione, Rivera, Carlos Jose Perez, Pinkney, Thomas D, Plas, Willemijn van der, Qureshi, Ahmad, Radenkovic, Dejan, Revell, Elliot J, Roberts, Keith, Roslani, April C, Rutegård, Martin, Segura-Sampedro, Juan José, Santos, Irène, Schache, Andrew, Schnitzbauer, Andreas A, Seyi-Olajide, Justina O, Sharma, Neil, Shaw, Catherine A, Shu, Sebastian, Soreide, Kjetil, Spinelli, Antonino, Stewart, Grant D, Townend, Philip, Tsoulfas, Georgios, Vidya, Raghavan, Vimalachandran, Dale, Warren, Oliver J, Wedderburn, Duane, EuroSurg, NA, European Society of Coloproctology (ESCP), NA, Global Initiative for Children's Surgery, NA, GlobalSurg, NA, GlobalPaedSurg, NA, ItSURG, NA, PTSurg, NA, SpainSurg, NA, Italian Society of Colorectal Surgery, NA, Association of Surgeons in Training, NA, Irish Surgical Research Collaborative (ISRC), NA, Transatlantic Australasian Retroperitoneal Sarcoma Working, NA, Italian Society of Surgical Oncology, NA, Booth, Lesley, Barker, Margaret, Barker, Neil, Cooke, Shirley, Doré, Suzanne, Horwood, Nigel, Runigamugabo, Emmy, Weir, Carrie Tierney, Bahrami-Hessari, Mike, Riaz, Asad, Shah, Jaffer, Safi, Mohammed, Thereska, Dariel, Dajti, Irida, Cheddadi, Riadh, Tidjane, Anisse, Quinteros, Carlos A, khelfaoui, Ahmed, Salem, Khalifa M, Riffi, Omar, Kacimi, Salah Eddine O, Loudjedi, Salim, Damerdji, Tidjani, Pantoja Pachajoa, Diana A, Palacios Huatuco, René M, Alvarez, Fernando A, Doniquian, Alejandro M, Abeldaño Zuñiga, Roberto A, Schlottmann, Francisco, Cobos, Carlos M, Gigena, Cecilia, Forneris, Agustin Albani, Duro, Agustin, García-Mansilla, Agustín M, Busnelli, Virginia Cano, Poggi, Catalina, Mercado, Pedro L, González, Marcos, Castro Lalin, Agustina F, Mayer, Horacio F, Brandariz, Rodrigo, Slullitel, Pablo A, Boudou, Rocio, Lobos, Pablo A, Uffelmann, María C, Petersen, Maria L, Luzzi, Emilia, Padilla Lichtenberger, Fernando L, Crespi Amor, María S, Zarratea, Celeste S, Esteves, Tomas A, Gemelli, Nicolas A, Tirapegui, Sebastián, Liyo, Juan, Scherñuk, Jordán, Boccalatte, Luis A, Balmaceda, Ruben D, D'Addino, Jose L, Caubet, María M, Calderón Arancibia, José A, Chwat, Carina, Morris, Brian, Avellaneda, Nicolas, Pedraza Salazar, Ivana I, Eskinazi, Diego G, Vargas, Lara, Muriel, María E, Lucchini, Sergio M, Gosselink, Martijn P, Davis, Amelia L, Barker, John C, Qin, Kirby R, Proud, David M, Cox, Daniel RA, Goh, Su Kah, Liu, David S, Wu, Damien M, Merrett, Neil D, Badiani, Sarit S, Sengupta, Shomik, Jain, Anshini, Steen, Christopher J, Wong, Enoch, Ip, Christopher CK, Leaning, Matthew G, McCartney, Conor B, Gananadha, Sivakumar, Yeap, Evie FW, Stevens, Sean G, Vu, Anh N, Martin, Sarah A, Stanley, Guy H M, Watson, David I, Townend, Philip J, Young, Thomas K, Cox, Georgia T, Dawson, Amanda C, Laura, Sharon E, Lun, Elizabeth W Y, Liang, Ina X, O'Neill, Christine J, Lott, Natalie J, Chuan, Alwin, Saravanan, SK, Gundara, Justin, Ong, Bee Shan, Nataraja, Ramesh M, Pacilli, Maurizio, Foley, Daniel M, Ooi, Geraldine J, Traeger, Luke, MacDermid, Ewan, Daruwalla, Jurstine, Hodgson, Russell, Heriot, Alexander G, Mulligan, Christopher S, Blefari, Nicholas D A, Purcell, Shaun S, Frankel, Adam J, Guerra, Glen R, Tefay, Joan S, Liang, Rhea W Y, Kroon, Hidde M, Farfus, Anthony W, Warren, Leigh R, Roy, Jennifer M, Whitfield, Robert J, Moller, Cea-Cea B, Davis, Sean S, Sammour, Tarik, Lam, Yick Ho, Kour, Kevin, Gan, Siang Wei, Coventry, Brendon J, Dawson, Joseph A, Batstone, Martin D, King, Sebastian K, Scott, Nathan J, Foo, Jonathan W, Shepherd, Talia, Page, Richard S, Choong, Peter F, Badgery, Henry E, Chong, Lynn, Taylor, Lillian, Hii, Michael W, Wright, Gavin M, Kong, Joseph CH, Watson, Matthew M, Bock, Jacob, Lidder, Surjit S, Elias, Patrick, Kanavathy, Sathisvaran, Koh, Cherry E, Chennakesavan, Srinivas Kondalsamy, Panuganti, Vishwakar, Latif, Haider, Yeung, Justin MC, Besson, Alex J, Tse, Eunice Q Y, Pitcher, Meron E, Taylor, Danielle L, Nahm, Christopher B, Lim, Alicia, Tree, Kevin, Aigner, Felix, Dawoud, Christopher, Foessleitner, Philipp, Zimmermann, Matthias, Wiedemann, Dominik, Findl, Oliver, Messner, Franka, Bauer, Marlies, Nägele, Felix, Kronberger, Irmgard E, Öfner, Dietmar, Härter, Bettina, Bicz, Nina Ru B, Zwittag, Paul M, Poier, Nikolaus, Navarro, Francisco Ruiz, Zebuhr, Yorck A, Köglberger, Paul, Wiesinger, Clemens G, Mathew, Erwin, Trivik-Barrientos, Felipe, Königsrainer, Ingmar, Djedovic, Gabriel, Cohnert, Tina U, Lumenta, David B, Singer, Georg, Leithner, Andreas, Kamolz, Lars-Peter, Andrianakis, Alexandros, Puchwein, Paul, Mikalauskas, Saulius, Kirchweger, Patrick, Függer, Reinhold, Mittermair, Christof, Russe, Elisabeth, Paal, Peter, Grünbart, Martin, de Cillia, Michael, Weiss, Helmut G, Steiner, Florian, Binder, Alf Dorian, Samadov, Elgun, Ibrahimli, Arturan, Muslumov, Gurbankhan, Bayramov, Nuru Y, Saunders, Jada M, Almoosa, Noora, Haj-Ibrahim, Huzifa, Maresch, Martin, Ezzdean, Weaam K, Juma, Isam M, Hasan, Layla H, Haider, Fayza HA, Alfaqawi, Ghassan Salman, Alam, Mohammed S, Islam, Shahnoor, Basher, AKM K, Mitul, Ashrarur Rahman, Islam, Nazmul, Oosterkamp, Antje E, Ahmed, Tanveer, Hannan, M Jafrul, Padmore, Greg M, Doyle, Alex F, LaCorbiniere, Karisha L, Boyce, Rico D R, Ragoobar, Paul T, Walkes, Keisha M Y, Haynes, Amelia A, Corbin, Sasha M, Litvina, Yauheniya A, Makhmudov, Anvar, Strypstein, Sébastien, Dhondt, Bert, Rasschaert, Ricky, Farid, Yasser, Wahib, El Mahdi, Pigeolet, Manon, Belle, Koen Van, De Wachter, Stefan, Komen, Niels, Vandeputte, Mathieu PJ, Jansen, Yanina JL, Stijns, Jasper, Eynde, Jef Van den, Olowo, Benedicte I, Feraudy, Israel C, Dragisic, Vedran, Martinovic, Vlatka, Barišić, Tatjana, Penava, Nikolina, Hudic, Igor, Delibegovic, Samir, Bogdanović, Gordana, Grgić, Gordana, Cerovac, Anis, Cerovac, Elmedina, Bedada, Alemayehu G, Baiocchi, Glauco, Wainstein, Alberto, Moisés, Elaine Christine D, Zani, Ana Carolina Tagliatti, de Campos Prado, Caio Antonio, Panis, Carolina, Rech, Daniel, Soares da Silva, Ruan Gabriel, Joviliano, Edwaldo E, Rezende, Ricardo F, 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Kassab, Mohamad B, Abou-Abbass, Hussein, Awad, Rabih F, El Assaad, Hadi, Serhan, Fatima Ghazi, Karout, Lina, Chowdhary, Anisa, Itani, Rania, Abu Hamrah, Ali A A, Bellah, Almoataz, Algatanesh, Nassib S, Duwebi, Mousab A, Alkouba, Esraa T, Algehani, Hala M, Alsharif, Monther, Al-maadany, Faraj S, Elkhafeefi, Fatimah S, Buimsaedah, Ahmad M, Ghazal, Sarah M, Amnaina, Mohamed G, Yagoub, Ghozlan Y, yahia, Hana Ramadan bin, Bareig, Elham Hussin, BenHamida, Bahaeddin, Alkimeeshi, Nayrouz, Marwan, Malak, Muhammed, Nawal Aldokali, Benamer, Eman M, Othman, Rema H, Momen, Ahmed A, Ayad, Kusay A, Aldokali, Nawal, Mohammed, Alsnosy Abdullah Khalefa, Sanousi, Enas F, Aboubakr, Saed J, Aboubakr, Islam F, Alttaira, Amal, Benatiga, Sara A, Alteerah, Ilham A, Aldressi, Wafa, Elhwety, Marwa O, Kalifa, Mohamed Fathi, Glessa, Maram A, Abubaker, Taha, Shembesh, Hassan A, Alansari, Arowa, Alkaseek, Akram M, Abusannuga, Malek Mohamed, Alawami, Mohammed A, Elhajdawe, Fras Ammar, Benamwor, Aihab Salem, Aween, 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Daniels, Ian R, Valverde, Joao, Lumley, Edward David John, Walton, Thomas J, Raptis, Dimitri A, Dimitrokallis, Nikolaos, Nathan, Arjun, Motallebzadeh, Reza, Chowdhury, Shihab, Ahmed, Rezwan F A, Mirnezami, Reza, Szakmany, Tamas, Knight, Dominic J, Al-Azzani, Waheeb, Davies, Huw R, Ooi, Setthasorn Zhi Yang, Oo, Khaing K, Cullis, Paul S, Peng, Ed, Demetriades, Andreas K, Tambyraja, Andrew L, Poon, Michael TC, Brennan, Paul M, Oikonomou, Dimitrios, Newman, Samuel E, Le Blevec, Louise, Otify, Mohamed, Szatmary, Peter, Devkaran, Bhavesh, Sochorova, Dana, Sohrabi, Catrin, Sivaprakasam, Rajesh, Goh, Mingzheng Aaron, Atkinson, Kate V, Soares, Delvene, Prce, Daniela, Cann, Johnathon P, Grobbelaar, Amy C, Bradley, Rebecca, Strauss, Helen J, Taha, Ahmed, Minicozzi, Annamaria, Thakur, Bhaskar, Hanoun, Abdullah, Goru, Poornanand, Baumber, Rachel M, Sobti, Anshul S, Cross, George WV, Havenhand, Tom, Antoniou, George A, Chauhan, Govind Singh, Vokshi, Ismail, Mahmud, Ayesha, Albanese, Erminia, Evans, Daisy, Madhuri, Thumuluru Kavitha, Horsnell, Jonathan D, Zalmay, Pardis, Davies, Angharad J, Aljanadi, Firas, Jeganathan, Reubendra, Jones, Mark, Kakos, Christos, vidya, Raghavan, El-Ghobashy, Alaa, Habib, Ahmed M, Reid, Jeremy P, Rajgor, Harshadkumar Dhirajlal, Ahmed, Omar, Branagan, Graham, Mohamedahmed, Ali Yasen Y, Al-Sabbagh, Ali, Chetty, Govind, Kelty, Clive J, EL-Wajeh, Yasin A M, Tomlinson, James E, Rominiyi, Ola, Sinha, Saurabh, Saad, Sanad, Sahu, Banchhita, Charalampakis, Vasileios, Enemosah, Ibrahim, Williams, Simon J, Yaqoob, Hassan N, Laurent, Edward P, Moreau, Joshua L, Frostick, Rhiannon, Parwaiz, Hammad, Aboelmagd, Karim, Pournaras, Dimitri J, Hristova, Kalina H, Iyengar, Karthikeyan P, Mohamed, Muyed, Artioukh, Dmitri Y, Anwar, Sibtain, Hussein, Mostafa K A, Omogbehin, Tomisin S, Herron, Jonathan B T, Labib, Amir, Patel, Preemal, Marsden, Samuel C, Mehdian, Roshana, Santhirakumaran, Gowthanan, Smelt, Jeremy, Agarwal, Ketan, Lancerotto, Luca, Sahnan, Kapil, Shalhoub, Joseph, Donnelly, Liam J, Erridge, Simon, Chidambaram, Swathikan, Luo, Xun, Bansal, Sujesh, Ryan, Neil AJ, Smith, Alexander C D, Flatman, Michael, Wafaie, Imad, Malik, Muhammad Isfandyar Khan, Thumbadoo, Ruben P, Hussain, Shoaib F, Henein, Christin, Hamad, Yousif T, Belgaumkar, Ajay P, Bosanquet, David C, Kolias, Angelos G, Choi, David, Marcus, Hani J, Horsfall, Hugo RM Layard, Khan, Danyal Z, Sahni, Arun, Millward, Christopher P, Render, Luke, Truss, Adam, Elmoslemany, Tarek, Parmar, Chetan, Hanger, Joseph, Sheen, Jonathon, Rait, Jaideep S, Foreman, Jennifer, Marzouqa, Natalie, Fontalis, Andreas, Voulalas, Grigorios, CHEONG, Ryan Chin Taw, Dindyal, Sanjay, Arumugam, Sathyaseelan, Ward, Thomas R W, Stephens, Alastair S, Douka, Eleftheria, Abou-Foul, Ahmad K, McKay, Siobhan C, Kitchen, Mark O, Rees-Stoner, Oliver DJ, Balasubramanya, Supriya, Akhtar, Muhammad Adeel, Warwick, Andrew J, Pawar, Shweta, Dubey, Vivek, Al-Yaseen, Mustafa W, Williams, Christopher YK, Laird, Alexander, Krishna, Kandaswamy, Anyaugo, Ngozi S, Wuraola, Obafemi K, Odejinmi, Funlayo, Craven, Joanna M, West, Charlotte L, Barter, Reece A, Navaratnam, Devaraj M, Malik, Shahbaz S, Mahendran, Vimaladhithan, Zilvetti, Miguel, Lovegrove, Richard E, Board, Tim N, Zeiton, Moez, Sarwar, Safdar A, Duff, Sarah E, Hsabo, Elmuiz A, Nugur, Ashwani Kumar, Morris, Richard M, Lala, Anil K, Kwan-Feinberg, Rita O, Ross, Samuel W, Dressler, Jeremy A, Evans, Faye M, Wason, Shaun E L, Vogel, Keianna R, Wang, Joanna C, Sulciner, Megan L, Hirji, Sameer, Raoof, Mustafa, Wolff, Christopher J, kent, Ilan, Turan, Alparslan, Teixeira, Pedro G, Olson, Kristofor A, Patel, Neil D, Krishnamoorthy, Vijay, Moris, Dimitrios, Rice, Henry E, Gabr, Hesham, Satoskar, Savni R, Castater, Christine A, Jmaileh, Manal, Payne, Rachel E, Kwon, David S, Aarabi, Shahram, Escobar, Pedro F, Kronenfeld, Joshua P, Dalton, Michael K, Etchill, Eric W, Haut, Elliott R, Vervoort, Dominique, Dehal, Ahmed, McKenney, Mark, Elkbuli, Adel, Gosain, Ankush, Abdelsattar, Zaid M, Naunheim, Matthew R, Burks, Ciersten A, Zhou, Allen S, Heng, Marilyn, Abohashem, Shady, Lozano-Calderón, Santiago A, Reisenauer, Janani S, Mouawad, Nicolas J, Diehl, Thomas M, Eriksson, Evert A, Marwaha, Jayson S, Schroeppel, Thomas J, LaRocca, Christopher J, Chang, Grace H, Hassan, Romana, Nosanov, Lauren B, Rickard, Jennifer L, Avraham, Jacob B, Petrone, Patrizio, Sferra, Joseph J, Hadaya, Joseph, Mead, Brittany S, Hauptman, Jason S, Ahmad, Maleeha, Meola, Antonio, Chang, Steven D, Ko, Ara, Specht, Katherine E, Choudhry, Asad, Encalada, Ronald Zerna, Poggio, Juan L, Xing, Hang, Glass, Nina E, Hooker, Robert, Martins, Paulo N, Scott, Erin M, Bankhead, Brittany K, Giorgakis, Emmanouil, Nigh, Joe, Osborn, Tamara, Tay Lasso, Erika L, Beswick, Daniel M, Berndtson, Allison E, Kaups, Krista L, Chen, Lee-lynn, Farrell, Michael S, Boeck, Marissa A, Vaysburg, Dennis M, Kassam, Al-Faraaz, Turner, Kevin M, Dyas, Adam R, Coleman, Julia R, Folsom, Megan, Lam, Christopher M, Kumer, Sean C, Larson, Kelsey, Turner, Scott, Guidry, Christopher, Reddy, Madhuri, Berbel, German, Findley, Austin, Beahm, David, Bur, Andres, Marlor, Derek, Houndschell, Corey, Carver, Shea, Ulrich, Alissa, Bhutiani, Neal, DiChiacchio, Laura, Abdou, Hossam, Napolitano, Lena M, Ghebre, Rahel, Bass, Gary Alan, Kaplan, Lewis J, Martin, Niels D, Duffy, Caoimhe C, Abdelhamid, Sultan S, Daley, Brian J, Roland, Christina L, Dumas, Ryan P, Ban, Vin Shen, Rajesh, Aashish, Davies, Mark G, Purudappa, Prabhudev P, Walters, Camila B, Lin, Nicole, Ruzgar, Nensi M, Ullrich, Sarah J, Trostchansky, Ivan, Bonilla-Cal, Fernando, Castedo, Fabiola, Sobrero, Helena, Acuña, Gastón, Álvarez, Sofía M, Tarigo, Josefina, Carbajal, Ana C, Carbajal, Ana, Reyes, Antonio R, Al-Eryani, Fatima A, Alqousi, Nardeen N, Alattas, Zainab, Al-Saban, Rafat A, Al-Shehari, Mohammed M, ALHammadi, Nawal T, Shream, Sarah A, Al-Naggar, Hamza M, Al-Qalisi, Lina M, Nadeesh, Areej E, Al-Samawi, Hytham H, Bajjah, Hadeel M, AL-Ameri, Saba A, Albably, Jamal F, Ghannam, Rana A, Shamsan, Amatallah H, Meead, Abdullah A, Al- Zubaidi, Riham Q, Zulait, Mohammed A, Najeeb, Halah, Alsayadi, Musaed M, Al-Mashreqi, Seham K, Al-Jomai, Najla A, Alsayadi, Ramzi A, Al-Naggar, Moath M, Almarashi, Hassan A, Musaeed, Hasna M, Al-Raimi, Ibrahim M, Ghanem, Hossam N, Al-Zazay, Karim A, AL-Mahdi, Shehab A, Almontaser, Amatalaleem S, Savopoulos, Vanessa A S, Munthali, James, Kabongo, Kizito M C, Mushiwokufa, Willard, Ngulube, Allan, Ntoto, Crispin, Magama, Praise T, Dzinotyiwei, Daniel, Chivanga, Shelton K, Dube, Ngqabutho S, Sanchez, Ernesto C, Moyo, Assel T, Chengahomwe, Antony, Chinyowa, Simbarashe, Siamuchembu, Maphios, Bondera, Tafadzwa, and Mushawarima, Trust
Published: 2022
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