Search

Your search keyword '"Patriarca A"' showing total 9,253 results
Start Over Author "Patriarca A"
9,253 results on '"Patriarca A"'

1. A Rare Case of Life-Threatening Jaundice Caused by Epstein-Barr Virus Infection and Secondary Cold Agglutinin Syndrome Successfully Treated with Rituximab

Author

Bellia M, Greco M, Lunghi M, Moia R, Gaidano G, and Patriarca A

Subjects
jaundice, epstein-barr virus infection, secondary cold agglutinin syndrome, rituximab, Medicine (General), R5-920
Abstract

Matteo Bellia, Mariangela Greco, Monia Lunghi, Riccardo Moia, Gianluca Gaidano, Andrea Patriarca Department of Translational Medicine, Division of Hematology, Universita’ del Piemonte Orientale and Azienda Ospedaliero-Universitaria Maggiore della Carità, Novara, 28100, ItalyCorrespondence: Matteo Bellia, Department of Translational Medicine, Division of Hematology, Università del Piemonte Orientale and Azienda Ospedaliero-Universitaria Maggiore della Carità, Via Solaroli 17, Novara, 28100, Italy, Tel +39-346-5988355, Email matteo.bellia@uniupo.itBackground: Jaundice and hyperbilirubinemia are common clinical problems characterized by the presence of bile pigments in the blood and their deposition in body tissues. This clinical condition can be associated with a broad spectrum of potential benign and malignant causes, including hepatic inflammation, biliary obstruction, impaired bilirubin conjugation and bilirubin overproduction Therefore, the hyperbilirubinemia diagnostic work-up sometimes can be highly challenging and its therapeutic management can require a multidisciplinary approach.Case Report: We report on a unique case of life-threatening jaundice and hepatic failure in a 20-year-old female who presented to the emergency room with complaints of fever, constant left abdominal pain and generalized profuse fatigue. A complete and detailed medical history, multiple tests for various infection, radiologic investigations and histological tests were performed in order to clarify the etiology of that rapidly progressive clinical condition. Based on the results, the patient jaundice was caused by an Epstein-Barr virus (EBV) infection and secondary cold agglutinin syndrome. Given the rare and complex diagnosis, multiple clinical specialists were asked to carry out the best patient management.Conclusion: This rare case highlights how challenging the differential diagnosis and treatment of hyperbilirubinemia can be, presenting a unique case of life-threatening multifactorial hepatic failure treated successfully with rituximab.Keywords: jaundice, Epstein-Barr virus infection, secondary cold agglutinin syndrome, rituximab

Published
2024

2. Laser-FLASH: radiobiology at high dose, ultra-high dose-rate, single pulse laser-driven proton source

Author

Flacco, A., Bayart, E., Giaccaglia, C., Monzac, J., Romagnani, L., Cavallone, M., Patriarca, A., DeMarzi, L., Fouillade, C., Heinrich, S., Lamarre-Jouenne, I., Parodi, K., Rösch, T., Schreiber, J., and Tischendorf, L.

Subjects
Physics - Medical Physics, Physics - Applied Physics, Physics - Plasma Physics
Abstract

Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose rates, short duration and broad energy spectrum. Typical temporal modality of laser-driven irradiation, the so-called fast-fractionation, results from the composition of multiple, temporally separated, ultra-short dose fractions. In this paper we present the use of a high-energy laser system for delivering the target dose in a single nanosecond pulse, for ultra-fast irradiation of biological samples. A transport line composed by two permanent magnet quadrupoles and a scattering system is used to improve the dose profile and to control the delivered dose-per-pulse. A single-shot dosimetry protocol for the broad-spectrum proton source using Monte Carlo simulations was developed. Doses as high as 20Gy could be delivered in a single shot, lasting less than 10ns over a 1.0cm diameter sample holder, at a dose-rate exceeding 10^9 Gy/s. Exploratory application of extreme laser-driven irradiation conditions, falling within the FLASH irradiation protocol, are presented for in vitro and in vivo irradiation. A reduction of radiation-induced oxidative stress in-vitro and radiation-induced developmental damage in vivo were observed, whereas anti-tumoral efficacy was confirmed by cell survival assay., Comment: 13 pages, 15 figures

Published
2024

3. Learning thresholds lead to stable language coexistence

Author

Tamm, Mikhail V., Heinsalu, Els, Scialla, Stefano, and Patriarca, Marco

Subjects
Physics - Physics and Society, Computer Science - Computation and Language
Abstract

We introduce a language competition model that incorporates the effects of memory and learning on the language shift dynamics, using the Abrams-Strogatz model as a starting point. On a coarse grained time scale, the effects of memory and learning can be expressed as thresholds on the speakers fractions. In its simplest form, the resulting model is exactly solvable. Besides the consensus on one of the two languages, the model describes additional equilibrium states that are not present in the Abrams-Strogatz model: a stable coexistence of the two languages, if both thresholds are low enough, so that the language shift processes in the two opposite directions compensate each other, and a frozen state coinciding with the initial state, when both thresholds are too high for any language shift to take place. We show numerically that these results are preserved for threshold functions of a more general shape., Comment: 5 pages, 3 figures

Published
2024

4. Long-time behavior of an anisotropic rigid body interacting with a Poiseuille flow in an unbounded 2D channel

Author

Bonheure, Denis, Hillairet, Matthieu, Patriarca, Clara, and Sperone, Gianmarco

Subjects
Mathematics - Analysis of PDEs
Abstract

We study the long-time behavior of an elliptic rigid body which is allowed to vertically translate and rotate in a 2D unbounded channel under the action of a Poiseuille flow at large distances. The motion of the fluid is modelled by the incompressible Navier-Stokes equations, while the motion of the solid is described through Newton's laws. In addition to the solid inertia and the hydrodynamic forces, we assume the dynamics of the solid is driven by internal elastic restoring forces but without any structural damping. Through a precise description of the motion of the elliptic body whenever it comes close to the channel boundaries, we prove global-in-time existence of weak solutions. Our second main contribution is a proof of return to equilibrium in case the amplitude of the Poiseuille flow is small. \black To our knowledge, this represents the first long-time analysis of fluid-solid interaction problems with a given non-trivial final state.

Published
2024

8. Homogenization of Leray's flux problem for the steady-state Navier-Stokes equations in a multiply-connected planar domain

Author

Patriarca, Clara and Sperone, Gianmarco

Subjects
Mathematics - Analysis of PDEs, 76M50, 76D05, 35B27, 35G60, 35Q31
Abstract

The steady motion of a viscous incompressible fluid in a multiply-connected, planar, bounded domain (perforated with a large number of small holes) is modeled through the Navier-Stokes equations with non-homogeneous Dirichlet boundary data satisfying the general outflow condition. Under either a symmetry assumption on the data or under a smallness condition on each of the boundary fluxes (therefore, no constraints on the magnitude of the boundary velocity are imposed), we apply the classical energy method in homogenization theory and study the asymptotic behavior of the solutions to this system as the size of the perforations goes to zero: it is shown that the effective equations remain unmodified in the limit. The main novelty of the present work lies in the obtainment of the required uniform bounds, which are achieved by a contradiction argument based on Bernoulli's law for solutions of the stationary Euler equations., Comment: 22 pages

Published
2023

11. Busulfan-fludarabine versus busulfan-cyclophosphamide for allogeneic transplant in acute myeloid leukemia: long term analysis of GITMO AML-R2 trial

Author

Cavallaro, Gianluca, Grassi, Anna, Pavoni, Chiara, Micò, Maria Caterina, Busca, Alessandro, Cavattoni, Irene Maria, Santarone, Stella, Borghero, Carlo, Olivieri, Attilio, Milone, Giuseppe, Chiusolo, Patrizia, Musto, Pellegrino, Saccardi, Riccardo, Patriarca, Francesca, Pane, Fabrizio, Saporiti, Giorgia, Rivela, Paolo, Terruzzi, Elisabetta, Cerretti, Raffaella, Marotta, Giuseppe, Carella, Angelo Michele, Nagler, Arnon, Russo, Domenico, Corradini, Paolo, Bernasconi, Paolo, Iori, Anna Paola, Castagna, Luca, Mordini, Nicola, Oldani, Elena, Di Grazia, Carmen, Bacigalupo, Andrea, and Rambaldi, Alessandro

Published
2024
Full Text
View/download PDF

12. Three-dimensional environment sensitizes pancreatic cancer cells to the anti-proliferative effect of budesonide by reprogramming energy metabolism

Author

Ibello, Eduardo, Saracino, Federica, Delle Cave, Donatella, Buonaiuto, Silvia, Amoroso, Filomena, Andolfi, Gennaro, Corona, Marco, Guardiola, Ombretta, Colonna, Vincenza, Sainz Jr, Bruno, Altucci, Lucia, De Cesare, Dario, Cobellis, Gilda, Lonardo, Enza, Patriarca, Eduardo Jorge, D’Aniello, Cristina, and Minchiotti, Gabriella

Published
2024
Full Text
View/download PDF

13. Axicabtagene ciloleucel treatment is more effective in primary mediastinal large B-cell lymphomas than in diffuse large B-cell lymphomas: the Italian CART-SIE study

Author

Chiappella, Annalisa, Casadei, Beatrice, Chiusolo, Patrizia, Di Rocco, Alice, Ljevar, Silva, Magni, Martina, Angelillo, Piera, Barbui, Anna Maria, Cutini, Ilaria, Dodero, Anna, Bonifazi, Francesca, Tisi, Maria Chiara, Bramanti, Stefania, Musso, Maurizio, Farina, Mirko, Martino, Massimo, Novo, Mattia, Grillo, Giovanni, Patriarca, Francesca, Zacchi, Giulia, Krampera, Mauro, Pennisi, Martina, Galli, Eugenio, Martelli, Maurizio, Ferreri, Andrés J. M., Ferrari, Silvia, Saccardi, Riccardo, Bermema, Anisa, Guidetti, Anna, Miceli, Rosalba, Zinzani, Pier Luigi, and Corradini, Paolo

Published
2024
Full Text
View/download PDF

15. Causal Analysis Based on Systems Theory (CAST) in Complex Systems: Application to the Delta Air Lines Flight 191 Aviation Accident

Author

Zarei, Esmaeil, Glish, Brittany, Patriarca, Riccardo, Li, He, Kacprzyk, Janusz, Series Editor, Novikov, Dmitry A., Editorial Board Member, Shi, Peng, Editorial Board Member, Cao, Jinde, Editorial Board Member, Polycarpou, Marios, Editorial Board Member, Pedrycz, Witold, Editorial Board Member, and Zarei, Esmaeil, editor

Published
2024
Full Text
View/download PDF

16. A Data-Driven Cyber Resilience Assessment for Industrial Plants

Author

Simone, Francesco, Cilli, Claudio, Di Gravio, Giulio, Patriarca, Riccardo, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Rocha, Alvaro, editor, Adeli, Hojjat, editor, Dzemyda, Gintautas, editor, Moreira, Fernando, editor, and Colla, Valentina, editor

Published
2024
Full Text
View/download PDF

18. Ericksen-Landau Modular Strain Energies for Reconstructive Phase Transformations in 2D crystals

Author

Arbib, Edoardo, Biscari, Paolo, Patriarca, Clara, and Zanzotto, Giovanni

Subjects
Condensed Matter - Materials Science, Condensed Matter - Statistical Mechanics
Abstract

By using modular functions on the upper complex half-plane, we study a class of strain energies for crystalline materials whose global invariance originates from the full symmetry group of the underlying lattice. This follows Ericksen's suggestion which aimed at extending the Landau-type theories to encompass the behavior of crystals undergoing structural phase transformation, with twinning, microstructure formation, and possibly associated plasticity effects. Here we investigate such Ericksen-Landau strain energies for the modelling of reconstructive transformations, focusing on the prototypical case of the square-hexagonal phase change in 2D crystals. We study the bifurcation and valley-floor network of these potentials, and use one in the simulation of a quasi-static shearing test. We observe typical effects associated with the micro-mechanics of phase transformation in crystals, in particular, the bursty progression of the structural phase change, characterized by intermittent stress-relaxation through microstructure formation, mediated, in this reconstructive case, by defect nucleation and movement in the lattice., Comment: 17 pages, 6 figures, links to 4 supplementary videos

Published
2022

19. Ropeginterferon phase 2 randomized study in low-risk polycythemia vera: 5-year drug survival and efficacy outcomes

Author

Barbui, Tiziano, Carobbio, Alessandra, De Stefano, Valerio, Alvarez-Larran, Alberto, Ghirardi, Arianna, Carioli, Greta, Fenili, Francesca, Rossi, Elena, Ciceri, Fabio, Bonifacio, Massimiliano, Iurlo, Alessandra, Palandri, Francesca, Benevolo, Giulia, Pane, Fabrizio, Ricco, Alessandra, Carli, Giuseppe, Caramella, Marianna, Rapezzi, Davide, Musolino, Caterina, Siragusa, Sergio, Rumi, Elisa, Patriarca, Andrea, Cascavilla, Nicola, Mora, Barbara, Cacciola, Emma, Calabresi, Laura, Loscocco, Giuseppe Gaetano, Guglielmelli, Paola, Gesullo, Francesca, Betti, Silvia, Ramundo, Francesco, Lunghi, Francesca, Scaffidi, Luigi, Bucelli, Cristina, Cattaneo, Daniele, Vianelli, Nicola, Bellini, Marta, Finazzi, Maria Chiara, Tognoni, Gianni, Rambaldi, Alessandro, and Vannucchi, Alessandro Maria

Published
2024
Full Text
View/download PDF

21. A real-life study of daratumumab-bortezomib-dexamethasone (D-VD) in lenalidomide exposed/refractory multiple myeloma patients: a report from the Triveneto Myeloma Working Group

Author

Barilà, Gregorio, Quaglia, Francesca Maria, Furlan, Anna, Pescosta, Norbert, Bonalumi, Angela, Marcon, Chiara, Pascarella, Anna, Tinelli, Martina, De March, Elena, Lico, Albana, Sartori, Roberto, Clissa, Cristina, De Sabbata, Giovanni, Nappi, Davide, Porrazzo, Marika, De Marchi, Roberta, Pavan, Laura, Tosetto, Alberto, Gherlinzoni, Filippo, Krampera, Mauro, Bassan, Renato, Patriarca, Francesca, Semenzato, Gianpietro, and Zambello, Renato

Published
2024
Full Text
View/download PDF

24. Diversity-induced decoherence

Author

Yamakou, Marius E., Heinsalu, Els, Patriarca, Marco, and Scialla, Stefano

Subjects
Nonlinear Sciences - Adaptation and Self-Organizing Systems
Abstract

We analyze the effect of small-amplitude noise and heterogeneity in a network of coupled excitable oscillators with strong time scale separation. Using mean-field analysis, we uncover the mechanism of a new nontrivial effect -- diversity-induced decoherence (DIDC) -- in which heterogeneity modulates the mechanism of self-induced stochastic resonance to inhibit the coherence of oscillations. We argue that DIDC may offer one possible mechanism via which, in excitable neural systems, generic heterogeneity and background noise can synergistically prevent unwanted resonances that may be related to hyperkinetic movement disorders., Comment: 6 pages, 4 figures, 51 references

Published
2022
Full Text
View/download PDF

26. Influence of invasion on natural selection in dispersal-structured populations

Author

Maeso, D. Navidad, Patriarca, M., and Heinsalu, E.

Subjects
Quantitative Biology - Populations and Evolution, Nonlinear Sciences - Adaptation and Self-Organizing Systems, Nonlinear Sciences - Pattern Formation and Solitons, Physics - Biological Physics
Abstract

We investigate how initial and boundary conditions influence the competition dynamics and outcome in dispersal-structured populations. The study is carried out through numerical modeling of the heterogeneous Brownian bugs model, in which individuals are characterized by diversified diffusion coefficients and compete for resources within a finite interaction range. We observed that if instead of being distributed randomly across the domain the population is initially localized within a small region, the dynamics and the stationary state of the system differ significantly. The outcome of the natural selection is determined by different competition processes, fluctuations, and spreading of the organisms., Comment: 16 pages, 8 figures

Published
2022
Full Text
View/download PDF

27. The interplay between diversity and noise in an excitable cell network model

Author

Scialla, Stefano, Patriarca, Marco, and Heinsalu, Els

Subjects
Physics - Biological Physics
Abstract

We study the interplay between diversity and noise in a 3D network of FitzHugh-Nagumo elements, with topology and dimensions chosen to model a pancreatic beta-cell cluster, as an example of an excitable cell network. Our results show that diversity and noise are not equivalent sources of disorder but have different effects on network dynamics. Their synchronization mechanisms may act independently of one another or synergistically, depending on the mean value of the diversity distribution compared to the intrinsic oscillatory range of the network elements., Comment: 7 pages, 5 figures

Published
2022
Full Text
View/download PDF

37. Clinical and histomorphometric evaluation of the vagina following treatment with CO2 laser, radiofrequency, and promestriene for genitourinary syndrome of menopause in breast cancer survivors on adjuvant therapy

Author

Cantarelli, Gabriela C., Bianchi-Ferraro, Ana M.H.M., Dedonatto, Chayanne, Fernandes, Marcela F.R., Vanzin, Rafaela B., Dardes, Rita C.M., Logullo, Angela F., de Almeida, Joaquim S., Facina, Gil, de Jármy-Di Bella, Zsuzsanna I.K., Sartori, Marair G.F., and Patriarca, Marisa T.

Published
2025
Full Text
View/download PDF

45. Determination of mycotoxin profiles characteristic of Alternaria strains isolated from Malbec grapes

Author

Vargas Trinidad Andrea, Quevedo Ganoza Fernando, Fernández Pinto Virginia, and Patriarca Andrea

Subjects
Microbiology, QR1-502, Physiology, QP1-981, Zoology, QL1-991
Abstract

The world grape production has increased, reaching 751 million quintals (Mql) in 2013. Many Alternaria species have been studied for their ability to produce secondary metabolites in foods, some of which have toxic properties with tenu- azonic acid (TA), alternariol (AOH), alternariol methyl ether (AME) being the most important ones. The aim was to determine the characteristic mycotoxin production profiles of Alternaria strains isolated from Malbec grapes in the Patagonian region of Argentina. Fifty Alternaria isolates (5 A. alternata, 5 A. arborescens and 40 A. tenuissima) were analyzed for the produc- tion of mycotoxins (TA, AOH and AME) in autoclaved rice media by High Performance Liquid Chromatography (HPLC). All isolates were found to be producers of mycotoxins; the 100% was producer of TA (0.016–21.031 mg/kg), 98% produced AOH (0.003–0.057 mg/kg) and 36% produced AME (0.001–0.133 mg/kg). Thirty-three isolates co-produced the three mycotoxins. In this study, it was demonstrated a high toxigenic potential of Alternaria isolates. Although Alternaria growth on grapes has been amply demonstrated, there are few studies about the incidence their more characteristic mycotoxin sand their toxicogenic capac- ity determination in grapes, wines and derivatives. In addition, mycotoxins studied in this work are not regulated in oenology. Therefore, further studies should be conducted to assess the health risk due to the presence of Alternaria toxins in grapes, wine, grape juice and raisins.

Published
2015
Full Text
View/download PDF

49. Prednisone vs high-dose dexamethasone in newly diagnosed adult primary immune thrombocytopenia: a randomized trial

Author

Mazzucconi, Maria Gabriella, Rodeghiero, Francesco, Avvisati, Giuseppe, De Stefano, Valerio, Gugliotta, Luigi, Ruggeri, Marco, Vianelli, Nicola, Fazi, Paola, Paoloni, Francesca, Sargentini, Valeria, Baldacci, Erminia, Ferretti, Antonietta, Martino, Bruno, Vincelli, Iolanda Donatella, Carli, Giuseppe, Fortuna, Stefania, Di Ianni, Mauro, Ranalli, Paola, Palandri, Francesca, Polverelli, Nicola, Lugli, Elisabetta, Rivolti, Elena, Patriarca, Andrea, Rago, Angela, D’Adda, Mariella, Gentile, Massimo, Siragusa, Sergio, Sibilla, Silvia, Carella, Angelo Michele, Rossi, Elena, Battistini, Roberta, Zaja, Francesco, Bocchia, Monica, Di Renzo, Nicola, Musto, Pellegrino, Crugnola, Monica, Giuffrida, Anna Chiara, Krampera, Mauro, Tafuri, Agostino, and Santoro, Cristina

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results