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1,319 results on '"Patil, Rahul A."'

8. An empirical study on rising application of (IoT+ medical solution= IoMTS) with integration of wearable devices and disease monitoring

Author

Ashokrao, Patil Rahul, Radhakrishna, Derle Deepak, Burje, Shrikant, Sinha, Anurag, Yazdani, Ghulam, Raj, Neeraj, Alkhayyat, Ahmad, Ojha, Rajat, Chan, Albert P. C., Series Editor, Hong, Wei-Chiang, Series Editor, Mellal, Mohamed Arezki, Series Editor, Narayanan, Ramadas, Series Editor, Nguyen, Quang Ngoc, Series Editor, Ong, Hwai Chyuan, Series Editor, Sachsenmeier, Peter, Series Editor, Sun, Zaicheng, Series Editor, Ullah, Sharif, Series Editor, Wu, Junwei, Series Editor, Zhang, Wei, Series Editor, Murugan, R, editor, Karsh, Ram Kumar, editor, Goel, Tripti, editor, and Laskar, Rabul Hussain, editor

Published
2024
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10. A Hybrid Model for Rain Prediction Using Machine Learning Algorithm

Author

Patil, Rahul, Kulkarni, Prashant, Kulkarni, Sarang, Bhatt, Abhishek, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Pant, Millie, editor, Deep, Kusum, editor, and Nagar, Atulya, editor

Published
2024
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11. Exergy Analysis of Deflagration Wave Propagating in Autoignitive H2 Mixture for Constant Pressure Boundary Conditions

Author

Patil, Rahul, Sreedhara, Sheshadri, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Singh, Krishna Mohan, editor, Dutta, Sushanta, editor, Subudhi, Sudhakar, editor, and Singh, Nikhil Kumar, editor

Published
2024
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25. Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin

Author

Ong, Seow Theng, Bajaj, Saumya, Tanner, Mark R, Chang, Shih Chieh, Krishnarjuna, Bankala, Ng, Xuan Rui, Morales, Rodrigo AV, Chen, Ming Wei, Luo, Dahai, Patel, Dharmeshkumar, Yasmin, Sabina, Ng, Jeremy Jun Heng, Zhuang, Zhong, Nguyen, Hai M, Sahili, Abbas El, Lescar, Julien, Patil, Rahul, Charman, Susan A, Robins, Edward G, Goggi, Julian L, Tan, Peng Wen, Sadasivam, Pragalath, Ramasamy, Boominathan, Hartimath, Siddana V, Dhawan, Vikas, Bednenko, Janna, Colussi, Paul, Wulff, Heike, Pennington, Michael W, Kuyucak, Serdar, Norton, Raymond S, Beeton, Christine, and Chandy, K George

Subjects
Biomedical Imaging, Arthritis, Neurosciences, Autoimmune Disease, Inflammatory and immune system, K(V)1.3, potassium channel, plant defensin, cell-penetrating peptide, peptide therapeutic, effector memory T cell, rheumatoid arthritis, autoimmune disease, grapevine, oil palm
Abstract

We describe a cysteine-rich, membrane-penetrating, joint-targeting, and remarkably stable peptide, EgK5, that modulates voltage-gated KV1.3 potassium channels in T lymphocytes by a distinctive mechanism. EgK5 enters plasma membranes and binds to KV1.3, causing current run-down by a phosphatidylinositol 4,5-bisphosphate-dependent mechanism. EgK5 exhibits selectivity for KV1.3 over other channels, receptors, transporters, and enzymes. EgK5 suppresses antigen-triggered proliferation of effector memory T cells, a subset enriched among pathogenic autoreactive T cells in autoimmune disease. PET-CT imaging with 18F-labeled EgK5 shows accumulation of the peptide in large and small joints of rodents. In keeping with its arthrotropism, EgK5 treats disease in a rat model of rheumatoid arthritis. It was also effective in treating disease in a rat model of atopic dermatitis. No signs of toxicity are observed at 10-100 times the in vivo dose. EgK5 shows promise for clinical development as a therapeutic for autoimmune diseases.

Published
2020

27. Online System for Identifying Need of Machine Maintenance by Mining Data Streams and Handling Concept Drifts

Author

Patil, Rahul, Patil, Pramod, Ghongade, Aditya, Dsa, Adriel, Lokhande, Parth, Munot, Harsh, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Shakya, Subarna, editor, Balas, Valentina Emilia, editor, Kamolphiwong, Sinchai, editor, and Du, Ke-Lin, editor

Published
2022
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28. Use of a Recurrent Neural Network to Identify Spammers on Twitter

Author

Patil, Rahul A., Chaudhari, Chetana C., Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Shakya, Subarna, editor, Balas, Valentina Emilia, editor, Kamolphiwong, Sinchai, editor, and Du, Ke-Lin, editor

Published
2022
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29. System for Analyzing Crime News by Mining Live Data Streams with Preserving Data Privacy

Author

Patil, Rahul, Patil, Pramod D., Kanase, Sayali, Bhegade, Nikita, Chavan, Vaishnavi, Kashetwar, Shreyas, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Shakya, Subarna, editor, Balas, Valentina Emilia, editor, Kamolphiwong, Sinchai, editor, and Du, Ke-Lin, editor

Published
2022
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36. Structure of Lymphocyte Potassium Channel K v1.3 and Modulation by Cell-Penetrating Immunomodulatory Plant Defensin

Author

Ong, Seow Theng, Liu, Sanling, Bajaj, Saumya, Zhao, Yue, Tanner, Mark R, Chang, Shih Chieh, Zhang, Yong, Krishnarjuna, Bankala, Ng, Xuan Rui, Morales, Rodrigo AV, Ming, Wei Chen, Luo, Dahai, Patel, Dharmeshkumar, Yasmin, Sabina, Ng, Jeremy Jun Heng, Nguyen, Hai M, Abbas, El Sahili, Lescar, Julien, Patil, Rahul, Charman, Susan A, Robins, Edward, Goggi, Julian, Peng, Wen Tan, Sadasivam, Pragalath, Ramasamy, Boominathan, SV, Hartimath, Dhawan, Vikas, Bednenko, Janna, Colussi, Paul, Wulff, Heike, Zhang, Longhua, Pennington, Michael, Kuyucak, Serdar, Norton, Raymond S, Beeton, Christine, Tian, Changlin, and Chandy, George

Subjects
Kv1.3, Kv beta-2, potassium channel, Cryo-electron microscopy, plant defensin, cell-penetrating peptide, peptide therapeutic, effector memory T cell, rheumatoid arthritis, atopic dermatitis, autoimmune disease, grapevine, oil palm
Published
2019

42. Single-Dose Drug Development Candidate for Schistosomiasis.

Author

Leas, Derek A., Keiser, Jennifer, Charman, Susan A., Shackleford, David M., Jones, Jeremy O., Campbell, Michael, Chen, Gong, Katneni, Kasiram, Patil, Rahul, Hu, Meiyu, Pham, Thao, Häberli, Cécile, Schulze, Thomas T., Neville, Andrew J., Wang, Xiaofang, Dong, Yuxiang, Davis, Paul H., and Vennerstrom, Jonathan L.

Published
2024
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44. A Vision-Based GPS-Aided Quadcopter for Emergency Vehicle Assistance

Author

Patil, Rahul B., Chaudhuri, Ron, Kumar, VTNS Pavan, Ramya, S., Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, K V, Santhosh, editor, and Rao, K.Guruprasad, editor

Published
2021
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46. Infotainment System Using CAN Protocol and System on Module with Qt Application for Formula-Style Electric Vehicles

Author

Patil, Rahul M., Chethan, K. P., Ramaprasad, Rahul, Nithin, H. K., Rangayyan, Srujan, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Gupta, Deepak, editor, Khanna, Ashish, editor, Bhattacharyya, Siddhartha, editor, Hassanien, Aboul Ella, editor, Anand, Sameer, editor, and Jaiswal, Ajay, editor

Published
2021
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