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The experiments were carried out during Rabi season for the three consecutive years of (2012 to 2014) at the Research Farm, College of Horticulture, Mandsaur (M.P.) under AICRP on M&AP, Rajmata Vijayaraje Scindia Krishi Vishwa Vidyalaya, Gwalior (M.P.). The treatments consisted of two sowing methods as M1-seed broad casting and M2-line sowing. Five seed rate S1-6, S2-8, S3-10, S4-12 and S5-15 kg/ha. These treatments were evaluated in Factorial Randomized Block Design with three replications. Significantly maximum plant height was recorded under treatment S5, maximum number of number of branches was recorded under treatment S2, maximum stem girth was recorded under treatment S2 and seed yield was recorded under treatment S2. [ABSTRACT FROM AUTHOR]

Ge30-xSe70Snx (8≤x≤20) glasses have been prepared using conventional melt quenching. The kinetics of the glass transition have been studied in terms of the variation of glass transition temperature with composition and heating rate. In addition the activation energy of the glass transition (Et) and its compositional dependence have been investigated using the Kissinger approach. The thermal stability of these glasses has been investigated using different stability parameters such as the kinetic resistance ΔT (Tc-Tg), the weighted thermal stability parameter H' ((Tc-Tg)/Tg) and S ((Tc-Tg) (Tp-Tc)/Tg) in terms of glass transition temperature (Tg), crystallization onset temperature (Tc) and peak crystallization temperature (Tp). It has been found that the thermal stability decreases with the increasing Sn content in the glassy alloys. A glassy sample is more stable if it has a higher kinetic resistance to crystallization. Accordingly, it has been observed that Ge22Se70Sn8 glassy sample is more thermally stable compared to the other members of the series. [ABSTRACT FROM AUTHOR]

CdS/PVC and ZnS/PVC nanocomposites were prepared by solution mixing taking different wt. % (2, 4, 6 & 8) of CdS and ZnS nanopowders synthesized through the wet chemical method respectively. The morphology of these nanocomposites has been characterized using transmission electron microscopy. The dynamic mechanical analyzer (DMA) was used to study the storage modulus and Tan δ of CdS/PVC and ZnS/PVC. The variation of storage modulus and glass transition temperature for CdS/PVC and ZnS/PVC nanocomposites with filler content has been explained on the basis of dispersion of nano fillers. An effort has also been made to determine the glass transition activation energy using Vogel-Fulcher-Tammann (VFT) equation. Effect of CdS and ZnS nanoparticle concentration on glass transition activation energy has been discussed. [ABSTRACT FROM AUTHOR]

A review of the recent work on II-VI semiconducting nanoparticle-polymer nanocomposites is presented. This review is not comprehensive but provides an overview of the processing techniques, trends in mechanical and thermal behaviuor and morphology of nanocomposites. A number of composite systems with amorphous polymer matrices and different nano-sized filler materials are discussed. [ABSTRACT FROM AUTHOR]

The tumor microenvironment and immune evasion function in a complex cellular network profoundly challenge the clinical outcome of promising therapies. Our recently published study reported that the subset of genes upregulated in ccRCC due to H3K4me1 and DNA demethylation potentially leads to an immunosuppressive environment. Thus, modulating H3K4me1 chromatin modifier SETD7 with a natural inhibitor in combination with immunotherapy might improve the immune landscape for a better therapeutic outcome. The present study was conducted via virtual screening and MD simulation using compounds from the literature, IMPPAT, and SuperNatural database. The phytochemical IMPHY002979 showed better binding affinity and lower energy than the reported R-PFI-2 and cyproheptadine inhibitors. The phytochemicals interact with the SET domain through H-bonding, as confirmed by MD simulation and molecular interaction analysis. Further, the compound was assessed using ADME parameters and free energy estimation, showing better pharmacokinetic properties. Therefore, the non-accessibility of the histone methyltransferase activity domain of SET7 with IMPHY002979 can downregulate H3K4me1 and, thereby, the expression of genes potentially responsible for immunosuppressive TME. Thus, patient stratification based on molecular markers for immunotherapy and combining epigenetic modulators with therapeutic drugs will improve the efficacy of immunotherapy in ccRCC., Competing Interests: Declarations. Competing interests: The authors declare they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Ethical approval: Not applicable. Consent to participate: Yes. All authors agreed to participate in this research. Consent for publication: Yes. All authors., (© 2024. The Author(s).)

Background: Dental caries is the most common disease in childhood and has an impact on general health status. The topical application of fluoride varnishes has been used for the prevention and control of dental caries due to their high fluoride content, adhesion capacity, and safety. Silver has a varied application in medicine as well as in dentistry due to its anticaries, antimicrobial, and antirheumatic potentials. The introduction of nanosilver fluoride (NSF) was made with advancements in technology to overcome the drawbacks of silver diamine fluoride (SDF)., Aim: To compare and evaluate the microhardness and microleakage of NSF varnish and sodium fluoride (NaF) varnish., Materials and Methods: An in vitro comparative experimental study was carried out between synthesized NSF and commercially available NaF, with 20 samples in each group. The specimens were sectioned and subjected to microhardness evaluation using Vickers microhardness testing and the dye penetration method to evaluate the microleakage., Results: The average microhardness was found to be 230.7218 VMH for NSF (group I), 198.9841 VMH for NaF (group II), and 91.6120 VMH for group III. These differences were statistically significant when compared with each other ( p = 0.002). In 50% of the samples, no dye penetration was seen in the NSF group, compared to the NaF varnish group, where 75% of the samples exhibited penetration onto the varnish interface or the varnish and tooth interface., Conclusion: Nanosilver fluoride proves to be an effective alternative to commercially available topical fluoride agents such as NaF. It has greater microhardness and lower microleakage than NaF and the control teeth., Clinical Significance: Nanosilver fluoride varnish can be used as a cost-effective alternative to NaF varnish and SDF. It can be applied with minimal training by healthcare workers or general practitioners., How to Cite This Article: Kritivasan S, Sogi HS, Jain M, et al. Comparative Evaluation of the Mechanical Efficiency of Nanosilver Fluoride and Sodium Fluoride Varnish: An In Vitro Study. Int J Clin Pediatr Dent 2024;17(5):539-544., Competing Interests: Source of support: Nil Conflict of interest: NoneConflict of interest: None, (Copyright © 2024; The Author(s).)