Search

Your search keyword '"Patiño-Morales, Carlos César"' showing total 9 results
Start Over Author "Patiño-Morales, Carlos César"
9 results on '"Patiño-Morales, Carlos César"'

2. Embryonic Hyperglycemia Disrupts Myocardial Growth, Morphological Development, and Cellular Organization: An In Vivo Experimental Study

Author

Jaime-Cruz, Ricardo, primary, Sánchez-Gómez, Concepción, additional, Villavicencio-Guzmán, Laura, additional, Lazzarini-Lechuga, Roberto, additional, Patiño-Morales, Carlos César, additional, García-Lorenzana, Mario, additional, Ramírez-Fuentes, Tania Cristina, additional, and Salazar-García, Marcela, additional

Published
2023
Full Text
View/download PDF

4. Bioelectric, tissue, and molecular characteristics of the gastric mucosa at different times of ischemia

Author

Huerta-Yepez Sara, Peña-Mercado Eduardo, Beltran Nohra E, Montecillo-Aguado Mayra, Patiño-Morales Carlos César, and Garcia-Lorenzana Mario

Subjects
Male, Pathology, medicine.medical_specialty, Time Factors, Ischemia, General Biochemistry, Genetics and Molecular Biology, Electric Impedance, Gastric mucosa, medicine, Animals, Rats, Wistar, Barrier function, Original Research, business.industry, Organ dysfunction, medicine.disease, medicine.anatomical_structure, Cyclooxygenase 2, Gastric Mucosa, Apoptosis, Reperfusion Injury, Shock (circulatory), Tumor necrosis factor alpha, medicine.symptom, business, Complication
Abstract

Gastrointestinal ischemia may be presented as a complication associated with late shock detection in patients in critical condition. Prolonged ischemia can cause mucosal integrity to lose its barrier function, triggering alterations that can induce organ dysfunction and lead to death. Electrical impedance spectroscopy has been proposed to identify early alteration in ischemia-induced gastric mucosa in this type of patients. This work analyzed changes in impedance parameters, and tissue and molecular alterations that allow us to identify the time of ischemia in which the gastric mucosa still maintains its barrier function. The animals were randomly distributed in four groups: Control, Ischemia 60, 90, and 120 min. Impedance parameters were measured and predictive values were determined to categorize the degree of injury using a receiver operating characteristic curve. Markers of inflammatory process and apoptosis (iNOS, TNFα, COX-2, and Caspase-3) were analyzed. The largest increase in impedance parameters occurred in the ischemia 90 and 120 min groups, with resistance at low frequencies (RL) and reactance at high frequencies (XH) being the most related to damage, allowing prediction of the occurrence of reversible and irreversible tissue damage. Histological analysis and apoptosis assay showed progressive mucosal deterioration with irreversible damage ( p

Published
2021

5. Antitumor Effects of Natural Compounds Derived from Allium sativum on Neuroblastoma: An Overview

Author

Patiño-Morales, Carlos César, primary, Jaime-Cruz, Ricardo, additional, Sánchez-Gómez, Concepción, additional, Corona, Juan Carlos, additional, Hernández-Cruz, Estefani Yaquelin, additional, Kalinova-Jelezova, Ivia, additional, Pedraza-Chaverri, José, additional, Maldonado, Perla D., additional, Silva-Islas, Carlos Alfredo, additional, and Salazar-García, Marcela, additional

Published
2021
Full Text
View/download PDF

9. Antitumor Effects of Natural Compounds Derived from Allium sativum on Neuroblastoma: An Overview.

Author

Patiño-Morales, Carlos César, Jaime-Cruz, Ricardo, Sánchez-Gómez, Concepción, Corona, Juan Carlos, Hernández-Cruz, Estefani Yaquelin, Kalinova-Jelezova, Ivia, Pedraza-Chaverri, José, Maldonado, Perla D., Silva-Islas, Carlos Alfredo, and Salazar-García, Marcela

Subjects
NEUROBLASTOMA, GARLIC, ALTERNATIVE medicine, NEURODEGENERATION, CARDIOVASCULAR diseases, CANCER
Abstract

Garlic (Allium sativum) has been used in alternative medicine to treat several diseases, such as cardiovascular and neurodegenerative diseases, cancer, and hepatic diseases. Several publications have highlighted other features of garlic, including its antibacterial, antioxidative, antihypertensive, and antithrombotic properties. The properties of garlic result from the combination of natural compounds that act synergistically and cause different effects. Some garlic-derived compounds have been studied for the treatment of several types of cancer; however, reports on the effects of garlic on neuroblastoma are scarce. Neuroblastoma is a prevalent childhood tumor for which the search for therapeutic alternatives to improve treatment without affecting the patients' quality of life continues. Garlic-derived compounds hold potential for the treatment of this type of cancer. A review of articles published to date on some garlic compounds and their effect on neuroblastoma was undertaken to comprehend the possible therapeutic role of these compounds. This review aimed to analyze the impact of some garlic compounds on cells derived from neuroblastoma. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results