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Background & Methods: The aim of the study is to evaluate of pathologies of posterior segment of eye using B scan ultrasonography in patients with opaque media, we registered 200 patients, all of whom had opaque media. These patients were prospectively enrolled at our institute. We selected 200 patients based on exclusion as well as inclusion standards. Results: Out of 200 patients, we observed B scan findings among posterior segment of eye pathologies as followings: Normal pathology (51.5%), Posterior Vitreous detachment (18.5%), PVD with vitreous degeneration (4%) vitreous haemorrhage (7.5%), vitreous degeneration (6%), Retinal Detachment (6%), Intraocular foreign body with vitreous haemorrhage (2.5%), optic nerve head coloboma (0.5%), Optic Nerve head drusen (1%), Choroidal Detachment (1.5%) and Pthysis bulbi (1%). Conclusion: USG B-scan can visualize the posterior segment of the eye even when the media is opaque due to conditions like cataracts, corneal opacities, or vitreous hemorrhage. This allows for the evaluation of structures that are otherwise hidden from direct view. Evaluation of Tumors: B scan can identify and characterize intraocular tumors such as melanoma or retinoblastoma, providing information on their size, shape, and location, which is essential for treatment planning. [ABSTRACT FROM AUTHOR]

This article develops the concept of heritage pharmacology as an encompassing critical framework in order to radically recast the interactions and efficacies of heritage as a particularly potent pharmacology of care. I critically engage with Stiegler's philosophic reflections On Pharmacology, which builds on Derrida's work and recasts pharmacology – a term usually reserved for that branch of the biomedical sciences dealing with drugs and their interactions and efficacies – in order to draw out the 'curative-toxic' dimensions at play in wider care tropes. By placing core concepts and practices of heritage and pharmacology in critical dialogue, my aim as heritage critic is to gain mutual insights into 'care', as that which links together the two domains of heritage and health, as otherwise distinct discourses, concepts, technics, and practices. My specific intervention rethinks the crucial role of 'heritage pathologies' and the underpinning memory-work at play within these tropes while grounding these in a case study of Jerusalem Syndrome (JS). I argue that it is the dynamic of heritage pathologies, best crystallized in JS debates, that invests us in the wider Stieglerian quest/ion of 'pharmacology', as a concern with 'what makes life worth living'. Such quests ultimately take this article into the realpolitik of Palestine. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Vitamin D (calciferol) is a key vitamin playing an important role in the regulation of the musculoskeletal, immune, cardiovascular and nervous systems. Vitamin D deficiency is a risk factor for multiple brain disorders. Mounting evidence shows robust neuroprotective properties of vitamin D, as well as its ability to improve neuronal function and reduce brain disorders. Here, we focus on the latest clinical and preclinical (rodent and zebrafish) data on the role of vitamin D as a neurosteroid hormone, including its role in regulating the synthesis and functions of neurotransmitters and neurotrophic factors. A better insight into the role of vitamin D in brain function may lead to novel approaches to the treatment and prevention of vitamin D deficiency-related brain disorders. [ABSTRACT FROM AUTHOR]

Purpose. The aim of the study was to investigate morphological and histological features of the gills, liver and blood of percids ­­­– pikeperch (Sander lucioperca Linnaeus, 1758) and perch (Perca fluviatilis Linnaeus, 1758) from different areas of the Zaporizhzhia Reservoir. Methodology. The study was conducted in two areas of the Zaporizhzhia Reservoir – in the Samara Bay and the lower part of the reservoir near the Viyskove village. The material was collected during research fish surveys in the summer-autumn period of 2024. The object of the study were age-3+ pikeperch and perch. The number of fishes used in the study was 20 specimens of each species. Hematological and histological studies were carried out according to generally accepted methods. The concentration of heavy metals in water samples was determined on a C115-M1 atomic absorption spectrophotometer in mg/L. Findings. According to the content of Cd, Mn, Cu, and Zn in both studied areas of the Zaporizhzhia Reservoir, there was an excess of the MPC for water bodies used for fishery purposes. The difference between the cytometric parameters of fish from different areas of the Zaporizhzhia Reservoir was mostly insignificant (р≥0.05), except for the width of the pikeperch nucleus and the area of ​​the perch erythrocyte nucleus, which were significantly larger in the fish of the Samara Bay (р≤0.05). The results of the study indicate the dependence of changes in the formed elements of the blood on the physiological state of the fish and on their environment. Among the studied fish of the lower part of the reservoir, the largest count of erythrocytes with pathological changes was observed in pikeperch, it was 1.32 times higher than in perch. Among fish of the Samara Bay, the highest count of pathologies in blood cells was also noted for pikeperch and was 1.17 times higher compared to that of perch. The results of these studies indicate an unfavorable ecological condition in both areas of the Zaporizhzhia Reservoir. The histological studies of the fish liver showed a number of pathological phenomena were revealed. The most common pathology of the liver cells of the studied fish from both areas of the reservoir was necrosis in pikeperch from the Samara Bay. Fish in the lower part of the reservoir had significantly fewer pathologies. Histological analysis of pikeperch and perch gills showed a high degree of pathological changes. The majority of pathologies were detected in pikeperch from the Samara Bay, which may indicate an average degree of pollution of the water by heavy metals and oil products. Based on these data, the histo-morphometric parameters of percid tissues can be used in the future to assess the ecological state of the water and the level of human impact of the Zaporizhzhia Reservoir, as well as be used as an additional indicator during the comprehensive assessment of the impact of anthropogenic factors on hydroecosystems. Originality. For the first time, a study of the morphological and histological characteristics of the gills, liver, and blood of percids (pikeperch and perch) from different areas of the Zaporizhzhia Reservoir was conducted. Practical Value. Histo-morphometric parameters of percid tissues can be used in the future to assess the ecological state of water and the level of human impact of the Zaporizhzhia Reservoir, as well as be used as an additional indicator during the comprehensive assessment of the impact of anthropogenic factors on hydroecosystems.

This study is devoted to defining the occurrence frequency of Cribra orbitalia and Porotic hyperostosis signs based on the data obtained and establishing the reasons for the spread of these pathological conditions in the study groups. The material for the study is series dating back to the Early, Middle and Late Bronze Ages from the Lower Volga region kurgan mounds. When analyzing bone remains, the occurrence of porotic hyperostosis on the skull and cribra orbitalia was taken into account. To identify significantly significant differences in the incidence of pathological abnormalities, the groups were compared using non-parametric mathematical criteria. Statistical calculations were carried out in the StatSoft, Inc. shell. (2011) STATISTICA. As a result of the study, it was established that the factors influencing the occurrence of signs of hemolytic diseases in the study group could be endemic malaria, helminths, as well as nutritional stress caused by systematic starvation, lack of vitamin C, folic acid, cobalamin and iron.

Objectives The aim of the research was to find out whether there is a relationship between the occurrence of dysfunctions in organisations and their wellbeing. Material and methods 121 participants took part in the study. The respondents were students from the Faculty of Management and Command, who are studying and have been employed for at least one year, and individuals who are not affiliated with the University but meet the condition of having been employed for at least one year. A proprietary survey questionnaire was used to collect empirical data. Results The research indicated that respondents perceived a correlation between the lack of wellbeing and the occurrence of dysfunction in the organisation. Respondents indicated in their answers, specific pathologies that they associate with the absence of wellbeing - this was job burnout. The research did not show a relationship with the seniority of the respondents. Conclusions While the research undertaken showed a relationship between the occurrence of organisational pathology indicated by the respondents such as job burnout, the empirical data obtained did not indicate a strong relationship in terms of the perception of organisational pathology in relation to seniority. In contrast, respondents perceive a link between the presence or absence of organisational pathology and wellbeing.

Purpose. The aim of the study was to investigate morphological and histological features of the gills, liver and blood of percids – pikeperch (Sander lucioperca Linnaeus, 1758) and perch (Perca fluviatilis Linnaeus, 1758) from different areas of the Zaporizhzhia Reservoir. Methodology. The study was conducted in two areas of the Zaporizhzhia Reservoir – in the Samara Bay and the lower part of the reservoir near the Viyskove village. The material was collected during research fish surveys in the summer-autumn period of 2024. The object of the study were age-3+ pikeperch and perch. The number of fishes used in the study was 20 specimens of each species. Hematological and histological studies were carried out according to generally accepted methods. The concentration of heavy metals in water samples was determined on a C115-M1 atomic absorption spectrophotometer in mg/L. Findings. According to the content of Cd, Mn, Cu, and Zn in both studied areas of the Zaporizhzhia Reservoir, there was an excess of the MPC for water bodies used for fishery purposes. The difference between the cytometric parameters of fish from different areas of the Zaporizhzhia Reservoir was mostly insignificant (р≥0.05), except for the width of the pikeperch nucleus and the area of the perch erythrocyte nucleus, which were significantly larger in the fish of the Samara Bay (р≤0.05). The results of the study indicate the dependence of changes in the formed elements of the blood on the physiological state of the fish and on their environment. Among the studied fish of the lower part of the reservoir, the largest count of erythrocytes with pathological changes was observed in pikeperch, it was 1.32 times higher than in perch. Among fish of the Samara Bay, the highest count of pathologies in blood cells was also noted for pikeperch and was 1.17 times higher compared to that of perch. The results of these studies indicate an unfavorable ecological condition in both areas of the Zaporizhzhia Reservoir. The histological studies of the fish liver showed a number of pathological phenomena were revealed. The most common pathology of the liver cells of the studied fish from both areas of the reservoir was necrosis in pikeperch from the Samara Bay. Fish in the lower part of the reservoir had significantly fewer pathologies. Histological analysis of pikeperch and perch gills showed a high degree of pathological changes. The majority of pathologies were detected in pikeperch from the Samara Bay, which may indicate an average degree of pollution of the water by heavy metals and oil products. Based on these data, the histo-morphometric parameters of percid tissues can be used in the future to assess the ecological state of the water and the level of human impact of the Zaporizhzhia Reservoir, as well as be used as an additional indicator during the comprehensive assessment of the impact of anthropogenic factors on hydroecosystems. Originality. For the first time, a study of the morphological and histological characteristics of the gills, liver, and blood of percids (pikeperch and perch) from different areas of the Zaporizhzhia Reservoir was conducted. Practical Value. Histo-morphometric parameters of percid tissues can be used in the future to assess the ecological state of water and the level of human impact of the Zaporizhzhia Reservoir, as well as be used as an additional indicator during the comprehensive assessment of the impact of anthropogenic factors on hydroecosystems. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Science is the property of Alcide De Gasperi University of Euroregional Economy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Recent advancements in medical imaging have greatly enhanced the application of computational techniques in digital pathology, particularly for the classification of breast cancer using in situ hybridization (ISH) imaging. HER2 amplification, a key prognostic marker in 20–25% of breast cancers, can be assessed through alterations in gene copy number or protein expression. However, challenges persist due to the heterogeneity of nuclear regions and complexities in cancer biomarker detection. This review examines semi-automated and fully automated computational methods for analyzing ISH images with a focus on HER2 gene amplification. Literature from 1997 to 2023 is analyzed, emphasizing silver-enhanced in situ hybridization (SISH) and its integration with image processing and machine learning techniques. Both conventional machine learning approaches and recent advances in deep learning are compared. The review reveals that automated ISH analysis in combination with bright-field microscopy provides a cost-effective and scalable solution for routine pathology. The integration of deep learning techniques shows promise in improving accuracy over conventional methods, although there are limitations related to data variability and computational demands. Automated ISH analysis can reduce manual labor and increase diagnostic accuracy. Future research should focus on refining these computational methods, particularly in handling the complex nature of HER2 status evaluation, and integrate best practices to further enhance clinical adoption of these techniques. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

We present the valuable contribution of the Arab written sources through its great authors versed in medicine for the knowledge of bioanthropological research. Although many works of medicine generated during the classic period of Islam are not preserved, which arises about this aspect, it is extracted from the most important, it comes to contributing information that, collected with the analyzes of documented remains in funeral areas, in this case of the Andalusian Mérida, open a field that can be extrapolated to other Maqabīr studied in the Iberian Peninsula.

Expansive soils commonly encountered beneath foundations often lead to structural issues inducing expensive repairs. With the increase of the frequency of dry summers and irregular rainfall patterns, the clayey and marly soils become more and more sensitive to shrinking and swelling phenomena. So to find solutions and improve the knowledge on such phenomena especially in temperate countries where the saturation state is considered as the usual soil state, the impact of the soil density on shrinkage was studied by varying the compaction mode and introducing a swelling step before shrinkage. As expected, dynamically or statically compacted clayey or marly soils exhibited high shrinkage deformation when the soil had a low density. The swelling before shrinkage impacted the soil structure but ultimately had a low effect on shrinkage deformation. Swelling deformation was also influenced by density; the denser the soil, the more sensitive the compacted soil became to swelling. Furthermore, compaction modes induced differences in swelling or shrinkage amplitude that couldn’t be explained by microstructural observations. Finally, results demonstrated that intact soil behavior after shrinkage could be extrapolated from swelling–shrinkage tests conducted on remolded soil samples, thus decreasing the cost of field investigations.

The purpose of this review is to summarize current possibility of contamination of milk and dairy products and human pathologies as well, that may occur if these products are not processed properly. Scientific literature was consulted to examine the methods of contamination of milk and dairy products. In raw or pasteurized milk stored at 5 °C was not reported that it can grow E. coli, however can grow slowly at higher temperatures. E. coli is considered a high-risk potential pathogen in cheese, due to its unusual ability to tolerate low pH values for long periods and it’s linked to unpasteurized raw milk.

This paper is based on a series of talks that the author gave at the University of Edinburgh in March 2023 on surfaces in positive characteristic. In particular, infinitesimal group schemes and their actions on algebraic surfaces are discussed, the structure of the automorphism group scheme of a surface of general type and the failure of the Kodaira vanishing theorem. [ABSTRACT FROM AUTHOR]

Expansive soils commonly encountered beneath foundations often lead to structural issues inducing expensive repairs. With the increase of the frequency of dry summers and irregular rainfall patterns, the clayey and marly soils become more and more sensitive to shrinking and swelling phenomena. So to find solutions and improve the knowledge on such phenomena especially in temperate countries where the saturation state is considered as the usual soil state, the impact of the soil density on shrinkage was studied by varying the compaction mode and introducing a swelling step before shrinkage. As expected, dynamically or statically compacted clayey or marly soils exhibited high shrinkage deformation when the soil had a low density. The swelling before shrinkage impacted the soil structure but ultimately had a low effect on shrinkage deformation. Swelling deformation was also influenced by density; the denser the soil, the more sensitive the compacted soil became to swelling. Furthermore, compaction modes induced differences in swelling or shrinkage amplitude that couldn't be explained by microstructural observations. Finally, results demonstrated that intact soil behavior after shrinkage could be extrapolated from swelling–shrinkage tests conducted on remolded soil samples, thus decreasing the cost of field investigations. [ABSTRACT FROM AUTHOR]

The purpose of this review is to summarize current possibility of contamination of milk and dairy products and human pathologies as well, that may occur if these products are not processed properly. Scientific literature was consulted to examine the methods of contamination of milk and dairy products. In raw or pasteurized milk stored at 5 °C was not reported that it can grow E. coli, however can grow slowly at higher temperatures. E. coli is considered a high-risk potential pathogen in cheese, due to its unusual ability to tolerate low pH values for long periods and it's linked to unpasteurized raw milk. [ABSTRACT FROM AUTHOR]

Pathologies affecting the bulls’genital tract are important reasons for seeking veterinary surgeon consultation. Abnormalities of testis and epididymis are accompanied with those of the penis and prepuce. Mechanical injuries are the most common causes, but other conditions, with more complex etiology, are also frequently identified. Among them are congenital alterations, and acquired infectious and non-infectious problems, namely: penile papillomatosis, penile hair ring, persistent penile frenulum, eversion of the prepuce, and others, that all prevent breeding soundness. This article presents some chosen pathologies of bull sexual organs including their incidence, the diagnostics and recommended treatment options. [ABSTRACT FROM AUTHOR]

ABSTRACT Timber bridges in Brazil, intended for rural roads and rural areas, present several problems due to the lack of design, structural calculation, and periodic maintenance by municipal administrations. This study evaluated a total of 10 timber bridges with a deck of sawn planks connected by nails to natural round beams, aiming to identify their main pathologies and provide minimum pre-sizing values for the used sections. The bridges were inspected on-site to measure the parts and identify the main problems. Subsequently, based on the Manual de Projeto e Construção de Pontes de Madeira and ABNT NBR 7190-1 (2022), we verified whether the diameter of the round beams found on site was adequate from the point of view of structural sizing using an Excel spreadsheet. Most of the analyzed bridges had spans of up to 15 m and problems related to the degradation of the timber and metal connections, reducing their useful life. As a result, the main construction recommendations for bridges are the use of timber treated with chromated copper arsenate (CCA) and galvanized connections to prevent corrosion. The use of the proposed pre-sizing tables is recommended to ensure minimum calculation values, considering the design vehicle classes and the minimum dimensions for the timber sections. This study aims to guide Brazilian municipal administrations and other interested parties in the construction of timber bridges for rural areas, obtaining safe, low-cost, and highly durable structures.

‘Medical Humanities’ (MH), the critical enclave of this cluster, is an interdisciplinary area of knowledge which examines human health and illness using the tools and insights of creative arts and humanities. MH endeavors to comprehend the diverse spectrum of physical and mental ailments by drawing from literature and various forms of artistic expression. The boom of MH both in the United States and Europe is manifested by the increase of this field of studies in undergraduate and graduate programs, professional training opportunities, career paths, conferences, and articles in prestigious academic journals, such as Medical Humanities, Intima: A Journal of Narrative Medicine, Journal of Medical Humanities, Literature and Medicine, or Arts and Health, among others. By consulting Scopus (http://www.scopus.com), the preeminent abstract and citation database for peer-reviewed research literature and conducting a search for 'Medical Humanities' spanning from 1970 to 2023, the findings in the 'Documents by Year' section (totaling 21,461 entries) reveal a consistent and steady upward trajectory. Commencing with a solitary document in 1971, the inaugural year recorded, the count surged to 54 in 1980, escalated to 498 in 2010, and surged to 1,581 in 2020, culminating in 2,417 entries by 2023. Furthermore, upon delving into the 'Documents by Subject Area', the analysis indicates that a significant majority of scholarly articles concerning MH originate from authors entrenched in the Health Sciences field (including Medicine, Nursing, Psychology, Neuroscience, Health professionals, Genetics), while only 15.9 percent stem from scholars within the Arts and Humanities domain. Hence, the authors of these articles, all affiliated with a research group located in Spain, envisioned the importance of enriching this field through their humanistic perspective, stemming from their roles as university professors and literature researchers.

Cyanobacteria are the only prokaryotes capable of performing oxygenic photosynthesis on Earth. Besides their traditional roles serving as primary producers, cyanobacteria also synthesize abundant secondary metabolites including carotenoids, alkaloids, peptides, which have been reported to possess medicinal potentials. More importantly, the advancement of synthetic biology technology has further expanded their potential biomedical applications especially using living/engineered cyanobacteria, providing promising and attractive strategies for future disease treatments. To improve the understanding and to facilitate future applications, this review aims to discuss the current status and future prospects of cyanobacterial-based biomedical engineering. Firstly, specific properties of cyanobacteria related with biomedical applications like their natural products of bioactive compounds and heavy metal adsorption were concluded. Subsequently, based on these properties of cyanobacteria, we discussed the progress of their applications in various disease models like hypoxia microenvironment alleviation, wound healing, drug delivery, and so on. Finally, the future prospects including further exploration of cyanobacteria secondary metabolites, the integration of bioactive compounds synthesized by cyanobacteria in situ with medical diagnosis and treatment, and the optimization of in vivo application were critically presented. The review will promote the studies related with cyanobacteria-based biomedical engineering and its practical application in clinical trials in the future.

Water in arid regions plays a vital role in the existence and development of living beings. The main aim of this work is to study the diversity and therapeutic properties of plant species that grow in the vicinity of water towers (constructions used to store and distribute drinking water) in the Saharan environment (south-western Algeria). Twenty-two floristic surveys were carried out in five representative sites to study the floristic diversity. The biological and phytogeographical spectra were established, and the therapeutic properties were determined for each plant species inventoried. The results show that the floristic richness is of the order of 41 species belonging to 39 genera and 16 botanical families, the most represented of which are the Asteraceae (19.51%) and Poaceae (17.07%). The biological spectrum showed the existence of 20 species of therophytes, and the phytogeographic spectrum indicated that most of the inventoried plant species belonged to the Saharo-Arabian biogeographic element (31.7%). The leaves (51.22%) are the most used for therapeutic aspects, while decoction is the most commonly used preparation method (60.98%). The plants with the highest importance values are Calotropis procera (27.78%), Phoenix dactylifera (16.67%), Cynodon dactylon and Tamarix gallica (15.56% each). This study shows that the various plant species inventoried offer important therapeutic properties for treating various pathologies.

Multiple studies have demonstrated the importance of androgen receptor (AR) splice variants (SVs) in the progression of prostate cancer to the castration-resistant phenotype and their utility as a diagnostic. However, studies on AR expression in non-prostatic malignancies uncovered that AR-SVs are expressed in glioblastoma, breast, salivary, bladder, kidney, and liver cancers, where they have diverse roles in tumorigenesis. AR-SVs also have roles in non-cancer pathologies. In granulosa cells from women with polycystic ovarian syndrome, unique AR-SVs lead to an increase in androgen production. In patients with nonobstructive azoospermia, testicular Sertoli cells exhibit differential expression of AR-SVs, which is associated with impaired spermatogenesis. Moreover, AR-SVs have been identified in normal cells, including blood mononuclear cells, neuronal lipid rafts, and the placenta. The detection and characterization of AR-SVs in mammalian and non-mammalian species argue that AR-SV expression is evolutionarily conserved and that AR-SV-dependent signaling is a fundamental regulatory feature in multiple cellular contexts. These discoveries argue that alternative splicing of the AR transcript is a commonly used mechanism that leads to an expansion in the repertoire of signaling molecules needed in certain tissues. Various malignancies appropriate this mechanism of alternative AR splicing to acquire a proliferative and survival advantage.

Background: Maxillary sinus pathologies present significant challenges in clinical management, often requiring surgical intervention for symptom relief and disease resolution. Endoscopic sinus surgery has emerged as a promising approach for the treatment of maxillary sinus pathologies, offering improved outcomes compared to traditional open techniques. However, comparative studies evaluating the efficacy of endoscopic approaches are limited. Objective: This study aimed to systematically compare the efficacy of endoscopic approaches versus traditional open techniques for managing maxillary sinus pathologies, including chronic sinusitis, nasal polyps, and mucoceles. Methods: A retrospective analysis was conducted on patients presenting with maxillary sinus pathologies at a tertiary care center. Inclusion criteria comprised patients undergoing endoscopic sinus surgery or traditional open procedures for maxillary sinus pathologies. Data collected included demographic information, preoperative symptoms, radiological findings, intraoperative details, postoperative outcomes, and follow-up assessments. Statistical analysis was performed to compare outcomes between the endoscopic and traditional surgical groups. Results: The study included [number] patients who underwent endoscopic sinus surgery (n=100) or traditional open procedures (n=100) for maxillary sinus pathologies. Endoscopic surgery demonstrated superior outcomes in terms of symptom resolution and recurrence rates compared to traditional open techniques. Additionally, endoscopic approaches were associated with reduced morbidity, shorter hospital stays, and faster recovery times. Conclusion: This comparative study provides further evidence supporting the efficacy of endoscopic approaches in managing maxillary sinus pathologies. Endoscopic sinus surgery offers superior outcomes compared to traditional open techniques, with improved symptom resolution and lower recurrence rates. These findings support the widespread adoption of endoscopic techniques as the preferred modality for managing maxillary sinus pathologies. [ABSTRACT FROM AUTHOR]

In this article I present a critical reading of employee recognition programmes. I utilize an immanent approach, drawing on the same principles that it is claimed underpin such programmes, namely the desire of needful subjects for recognition in the form of self-respect and esteem, and an anticipation of the organizational relations that are themselves a prerequisite for such recognition. These principles are articulated through a reading of Axel Honneth's critical theory of intersubjective recognition as a necessary condition for what he refers to as fulfilled self-realization and social freedom. In doing so, I suggest that, rather than facilitating the conditions and benefits of intersubjective recognition, internal pathological tendencies towards reification, disrespect and compelled identification result in such programmes undermining the ontological conditions necessary for recognition to flourish, threatening both individual and organizational harm. [ABSTRACT FROM AUTHOR]

Long non-coding (lnc) RNAs, once considered as junk and useless, are now broadly recognized to have major functions in the cell. LncRNAs are defined as non-coding RNAs of more than 200 nucleotides, regulate all steps of gene expression. Their origin is diverse, they can arise from intronic, intergenic or overlapping region, in sense or antisense direction. LncRNAs are mainly described for their action on transcription, while their action at the translational level is more rarely cited. However, the bibliography in the field is more and more abundant. The present synopsis of lncRNAs involved in the control of translation reveals a wide field of regulation of gene expression, with at least nine distinct molecular mechanisms. Furthermore, it appears that all these lncRNAs are involved in various pathologies including cancer, cardiovascular and neurodegenerative diseases. [ABSTRACT FROM AUTHOR]

Prebiotic compounds were originally defined as "a nondigestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon, and thus improves host health"; however, a significant modulation of the definition was carried out in the consensus panel of The International Scientific Association for Probiotics and Prebiotics (ISAPP), and the last definition states that "prebiotics are substrates that are selectively utilized by host microorganisms conferring a health benefit". Health effects of prebiotics compounds attracted the interest of researchers, food companies and Regulatory Agencies, as inferred by the number of articles on Scopus for the keywords "prebiotic" and "health effects", that is ca. 2000, for the period January 2021–January 2024. Therefore, the aim of this paper is to contribute to the debate on these topics by offering an overview of existing knowledge and advances in this field. A literature search was performed for the period 2012–2023 and after the selection of the most relevant items, the attention was focused on seven conditions for which at least 8–10 different studies were found, namely colorectal cancer, neurological or psychiatric conditions, intestinal diseases, obesity, diabetes, metabolic syndrome, and immune system disorders. In addition, the analysis of the most recent articles through the software VosViewer version 1.6.20 pointed out the existence of five clusters or macro-categories, namely: (i) pathologies; (ii) metabolic condvitions; (iii) structure and use in food; (iv) immunomodulation; (v) effect on gut microbiota. [ABSTRACT FROM AUTHOR]

Copyright of Romanian Journal of Veterinary Medicine & Pharmacology is the property of Innovation in Health Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Considering the various problems caused by infiltration in civil construction, this study aimed to identify the most appropriate waterproofing methods for different types of surfaces. A study was conducted on the mechanisms of water infiltration on surfaces and the waterproofing methods available on the market, focusing on asphalt blankets, in addition to a literature review highlighting state-of-the-art methods on this topic. A case study was also conducted in a residence in Nova Lima, Brazil, analyzing different waterproofing techniques, including their characteristics and stages. Among the conclusions, it is highlighted that the implementation of adequate project, installation, inspection, and maintenance techniques can significantly reduce the waterproofing failure rate and repair costs, and that the excellent choice of materials, along with the skill of the labor force in the application, is fundamental to guarantee the adequate performance of these materials in buildings.

Background: Diagnostic laparoscopy is often used when a patient is suspected of having acute appendicitis. The aim of this study was to assess the rate of other pathologies found during diagnostic laparoscopy for suspected acute appendicitis. Methods: This systematic search included studies with ≥100 patients who received laparoscopy for suspected acute appendicitis and reported on the histopathologic and other intra-abdominal findings. We performed a meta-analysis estimating the rate of other pathologies, and a sensitivity analysis excluding smaller cohorts (≤500 patients). Age groups, sex, specific findings, and geographic regions were investigated. Certainty of evidence was assessed with GRADE. Results: A total of 27 studies were included covering 25,547 patients and of these 793 had an unexpected pathology. The findings were benign pathology in the appendix (34%), malignancy (30%), gynecologic pathology (5%), gastrointestinal pathology (4%), or unspecified (27%). Meta-analysis showed an overall rate of unexpected findings of 3.5% (95% CI 2.7–4.3; moderate certainty), and the sensitivity analysis showed similar results. Malignancy found in the appendix when treating suspected acute appendicitis was 1.0% (95% CI 0.8–1.3%; high certainty). Conclusion: The rate of other histopathological findings in patients with suspected acute appendicitis was low and a malignancy in appendix was found in 1% of patients. [ABSTRACT FROM AUTHOR]

Considering the various problems caused by infiltration in civil construction, this study aimed to identify the most appropriate waterproofing methods for different types of surfaces. A study was conducted on the mechanisms of water infiltration on surfaces and the waterproofing methods available on the market, focusing on asphalt blankets, in addition to a literature review highlighting state-of-the-art methods on this topic. A case study was also conducted in a residence in Nova Lima, Brazil, analyzing different waterproofing techniques, including their characteristics and stages. Among the conclusions, it is highlighted that the implementation of adequate project, installation, inspection, and maintenance techniques can significantly reduce the waterproofing failure rate and repair costs, and that the excellent choice of materials, along with the skill of the labor force in the application, is fundamental to guarantee the adequate performance of these materials in buildings. [ABSTRACT FROM AUTHOR]

Copyright of Arquivos de Ciências da Saúde da UNIPAR is the property of Associacao Paranaense de Ensino e Cultura and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction. The article introduces anthropological materials instrumental in tracing processes inherent to Middle Bronze Age Kalmykia’s population referred to as Catacomb culture. Goals. The work attempts an analysis of the age-sex structure in the Catacomb population to have inhabited the Sarpa Lowland. Materials and methods. The age-sex characteristics of the buried individuals have been identified via a comprehensive anthropological program involving traditional anthropology research techniques, documentation of stress markers revealed and physiological properties of skeletons, injuries and traumas. The study examines human skeletal remains from Catacomb burials nowadays primarily stored at the Osteological Materials Repository of Kalmyk Scientific Center (RAS). Data on missing anthropological materials have been reconstructed with the aid of photographs contained in corresponding field reports. Results. The undertaken research efforts aim at characterizing the archaeological sites to have yielded the anthropological materials; outlining age-sex properties of the buried individuals; identifying and describing some pathologies, physiological stress markers and traumas; comparing the paleopopulation to that of Middle Bronze Age Dagestan (neighboring region) for similarities and differences on certain demographic parameters. The insights into the newly introduced materials make it possible to trace processes of population formation across the Volga-Manych steppe in the Middle Bronze Age. The study is the first to use anthropological materials from Kalmykia’s excavations stored at Kalmyk Scientific Center (RAS) as object of paleodemographic research, and introduces new data into scientific discourse.

Background. Research into human movement dysfunction is receiving increasing attention as the proportion of older adults and the number of obese people in the world’s population continues to rise. Compared to the other joints in the lower limb, the knee joint is very delicate and susceptible to injury. Knee deficits are a prevalent physical ailment that substantially influences the day-to-day functionality and emotional welfare of those who suffer from them. Supporting the body weight, helping maintain lower limb balance, and absorbing shock while the body is in motion are the primary factors contributing to these deficits. Movement biomechanics is an essential subfield of biomechanics that investigates how bones, muscles, ligaments, and tendons coordinate with one another throughout different types of human movement. Aims. The purpose of this review is to devise and investigate novel approaches to the use of mobile devices in knee rehabilitation. This research investigates how mobile devices like smartphones and tablets are used in rehabilitation. Our primary emphasis will be on mobile applications that provide individualized workouts, continuous monitoring, and immediate feedback to patients. Conclusions. Undoubtedly, the technology will continue to develop and grow over time and be integrated with many other electronic health systems and devices. As a direct consequence of this advancement, physiotherapists will have more opportunities to assist in designing and developing exoskeletons that may be used throughout rehabilitation. [ABSTRACT FROM AUTHOR]

Numerous studies have reported positive associations between certain biologically active compounds, with pharmacological properties, such as nutraceuticals, contained in some foods and various pathologies. The term "nutraceutical" currently varies from country to country, referring to a number of valuable molecules, derived from organic sources (plants) or foods such as polyphenols, essential amino acids, antioxidants, soluble fiber, polyunsaturated fatty acids ( PUFA), prebiotics, prebiotics, which act at the cellular level, in combating oxidative stress and inflammatory processes and / or in altering the expression of some genes. The discovery of the many benefits attributed to these products and the ever-changing lifestyle have contributed to increasing consumer confidence in nutraceutical and functional foods around the world, and there is a growing interest in improving the quality of life and adopting a healthy lifestyle. to prevent or reduce the risk of disease. Based on these considerations, this paper aims to review some scientific evidence obtained from in vitro / in vivo studies, which supports the beneficial effects of some nutraceuticals and their medical implications in various pathologies. [ABSTRACT FROM AUTHOR]

This paper focuses on the 1,224 bird remains found during the excavations of 1990–2015 in the Vilnius Lower Castle, Lithuania. The faunal material originates from a wide time span of the 13th to the 19th centuries. To explore the bird consumption in different periods of occupation of the castle and between different social strata, we analyzed the bird specimens by morphological characteristics. The study included taxonomical identification, recording the taphonomic features and pathologies, and assessing age and sex. As expected, the majority of the bones belong to the domestic chicken, but it is mostly the presence of wild taxa such as hawk, swan, and wild galliforms that demonstrates the various roles the birds played in peoples' everyday lives. Additionally, a few pathologies like avian osteopetrosis were identified that are unique to the eastern Baltic region. [ABSTRACT FROM AUTHOR]

Copyright of Comprendre: Revista Catalana de Filosofía is the property of Herder Editorial S.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract This article presents a study of the impacts caused by Fundão dam failure in buildings from Gesteira district, Barra Longa city, Brazil. The analyzed dataset was built using technical reports from surveys carried out in 152 buildings. Principal component analysis was capable of explain the interdependence of data variable and allowed conditions of understand the consequences and evidenced pathologies. Heavy vehicle traffic caused more damage (57% of buildings) to the studied buildings than the contact with the tailing mud (43% of buildings).

Milk is the most traded, processed and consumed dairy product in the world, approximately 113.7 to 150 kg per capita. However, one of the food safety and human health problems worldwide is aflatoxin M1 (AFM1), present exclusively in milk and its derivatives, because this mycotoxin is heat-resistant to common food industrialization processes and is capable of producing hepatotoxicity, carcinogenicity, genotoxicity and immunosuppression in humans, so there are international regulations that establish parameters ranging from 0.03 to 0.250 μg/kg depending on each country. The present review aims at compiling information on mycotoxins and specifically on AFM1 from its biotransformation from dairy cattle until the pathologies in humans associated with its consumption.

Prebiotic compounds were originally defined as “a nondigestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon, and thus improves host health”; however, a significant modulation of the definition was carried out in the consensus panel of The International Scientific Association for Probiotics and Prebiotics (ISAPP), and the last definition states that “prebiotics are substrates that are selectively utilized by host microorganisms conferring a health benefit”. Health effects of prebiotics compounds attracted the interest of researchers, food companies and Regulatory Agencies, as inferred by the number of articles on Scopus for the keywords “prebiotic” and “health effects”, that is ca. 2000, for the period January 2021–January 2024. Therefore, the aim of this paper is to contribute to the debate on these topics by offering an overview of existing knowledge and advances in this field. A literature search was performed for the period 2012–2023 and after the selection of the most relevant items, the attention was focused on seven conditions for which at least 8–10 different studies were found, namely colorectal cancer, neurological or psychiatric conditions, intestinal diseases, obesity, diabetes, metabolic syndrome, and immune system disorders. In addition, the analysis of the most recent articles through the software VosViewer version 1.6.20 pointed out the existence of five clusters or macro-categories, namely: (i) pathologies; (ii) metabolic condvitions; (iii) structure and use in food; (iv) immunomodulation; (v) effect on gut microbiota.

Numerous studies have reported positive associations between certain biologically active compounds, with pharmacological properties, such as nutraceuticals, contained in some foods and various pathologies. The term "nutraceutical" currently varies from country to country, referring to a number of valuable molecules, derived from organic sources (plants) or foods such as polyphenols, essential amino acids, antioxidants, soluble fiber, polyunsaturated fatty acids ( PUFA), prebiotics, prebiotics, which act at the cellular level, in combating oxidative stress and inflammatory processes and / or in altering the expression of some genes. The discovery of the many benefits attributed to these products and the ever-changing lifestyle have contributed to increasing consumer confidence in nutraceutical and functional foods around the world, and there is a growing interest in improving the quality of life and adopting a healthy lifestyle. to prevent or reduce the risk of disease. Based on these considerations, this paper aims to review some scientific evidence obtained from in vitro / in vivo studies, which supports the beneficial effects of some nutraceuticals and their medical implications in various pathologies.

Reinforcement of a structure is necessary in unpredictable changes or also for rehabilitation, due to exposure to weather conditions, causing considerable damage that can lead to the collapse of the structure. The present study aims to evaluate the behavior of the strengthening with sheets of glass fiber reinforced polymer (GFRP) with thicknesses of 3 mm, bonded with structural epoxy-based adhesive applied in the shear area of reinforced concrete beams, spaced in three different configurations and bonded on the two faces of the beam. The beams were cracked previously to simulate a damaged structure and strengthened later to obtain the maximum load of rupture after the application of the strengthening. With the obtained results it can be verified an increase of ductility in the reinforced concrete beams. The increase of the load capacity was obtained in the beams with strengthening with smaller spacing between the sheets.