45 results on '"Pathologie Moleculair"'
Search Results
2. RT-PCR assay to detect FGFR3::TACC3 fusions in formalin-fixed, paraffin-embedded glioblastoma samples.
3. Formalin-Fixed, Paraffin-Embedded-Targeted Locus Capture: A Next-Generation Sequencing Technology for Accurate DNA-Based Gene Fusion Detection in Bone and Soft Tissue Tumors
4. p-mTOR, p-ERK and PTEN Expression in Tumor Biopsies and Organoids as Predictive Biomarkers for Patients with HPV Negative Head and Neck Cancer
5. Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D-CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials
6. Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours
7. PRAME Staining in Sinonasal Mucosal Melanoma: A Single-Center Experience
8. Genetic variants found in paediatric oncology patients with severe chemotherapy-induced toxicity: A case series
9. Assessment of Cancer Predisposition Syndromes in a National Cohort of Children With a Neoplasm
10. NTRK rearrangements in a subset of NF1-related malignant peripheral nerve sheath tumors as novel actionable target
11. Case Report: Immune dysregulation associated with long-lasting regression of a (pre)leukemic clone
12. Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing
13. Molecular Characterization Reveals Subclasses of 1q Gain in Intermediate Risk Wilms Tumors
14. Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program 'iTHER'
15. Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: A proof-of-concept study
16. BRAF and NRAS Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma
17. A Toolkit for Profiling the Immune Landscape of Pediatric Central Nervous System Malignancies
18. Trastuzumab and pertuzumab combination therapy for advanced pre-treated HER2 exon 20-mutated non-small cell lung cancer
19. Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments
20. FAIR Genomes metadata schema promoting Next Generation Sequencing data reuse in Dutch healthcare and research
21. Towards diagnostic criteria for malignant deep penetrating melanocytic tumors using single nucleotide polymorphism array and next-generation sequencing
22. Improved Gene Fusion Detection in Childhood Cancer Diagnostics Using RNA Sequencing
23. Patients With Rare Cancers in the Drug Rediscovery Protocol (DRUP) benefit from Genomics - Guided Treatment
24. Mind your head: two cases of mucosal metastasis of BRAF-mutated melanoma of the scalp
25. Mismatch repair deficiency in early-onset duodenal, ampullary, and pancreatic carcinomas is a strong indicator for a hereditary defect
26. Author Correction: Establishment of patient-derived cancer organoids for drug-screening applications (Nature Protocols, (2020), 15, 10, (3380-3409), 10.1038/s41596-020-0379-4)
27. CCN2 Aggravates the Immediate Oxidative Stress–DNA Damage Response following Renal Ischemia–Reperfusion Injury
28. The end of the laboratory developed test as we know it?: Recommendations from a national multidisciplinary taskforce of laboratory specialists on the interpretation of the IVDR and its complications
29. Patients with bi-allelic BRCA1/2 inactivation respond to olaparib treatment across histologic tumor types
30. Genome-wide copy number variations as molecular diagnostic tool for cutaneous intermediate melanocytic lesions: a systematic review and individual patient data meta-analysis
31. Expanding spectrum of 'spitzoid' lesions: a small series of 4 cases with MAP2K1 mutations
32. Multicenter comparison of Molecular Tumor Boards in the Netherlands: definition, composition, methods and targeted therapy recommendations
33. Establishment of Pancreatic Organoids from Normal Tissue and Tumors
34. Comel-Netherton syndrome: A local skin barrier defect in the absence of an underlying systemic immunodeficiency
35. Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia
36. Establishment of patient-derived cancer organoids for drug-screening applications
37. Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
38. Modifying graft-versus-host disease in a humanized mouse model by targeting macrophages or b-cells
39. Changes in vascular density in resected tissue of 97 patients with mild malformation of cortical development, focal cortical dysplasia or TSC-related cortical tubers
40. Occurrence of an Abscopal Radiation Recall Phenomenon in a Glioblastoma Patient Treated with Nivolumab and Re-Irradiation
41. Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre- and end-stage heart failure
42. Clinical versus histological grading in the assessment of cutaneous graft versus host disease
43. One-fits-all pretreatment protocol facilitating Fluorescence In Situ Hybridization on formalin-fixed paraffin-embedded, fresh frozen and cytological slides
44. The Translational Landscape of the Human Heart
45. Granzymes A and K differentially potentiate LPS-induced cytokine response
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