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4. Clinical and radiographic assessment of implant-supported rehabilitation of partial and complete edentulism: a 2 to 8 years clinical follow-up

Author

Manicone, P. F., Passarelli, P. C., Bigagnoli, S., Roberta PASTORINO, Manni, A., Pasquantonio, G., and D Addona, A.

Subjects
Dental Implants, Male, Mucositis, complications, Alveolar Bone Loss, Reproducibility of Results, success, complications, Peri-Implantitis, Settore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE, Maxilla, Humans, Female, Dental Prosthesis, Implant-Supported, prosthesis, success, dental implants, prosthesis, Aged, Follow-Up Studies
Abstract

The aim of this study was to find out the rates of survival and success of implant rehabilitation, and the influence of some risk indicators on the medium- and long-term prognosis.Of the 102 patients eligible for this study rehabilitated with dental implants during the years 2009-2015, 75 patients with 156 implants of different implant systems placed and loaded by the same team were recalled. For each subject, pocket-probing depth, bleeding on probing, plaque buildup, mobility of the fixtures, and the presence/absence of prosthetic complications were recorded. Radiographic evaluation was based on the analysis of bone levels around the fixtures, as shown by intraoral radiographs.The average follow-up was 4.4 years, ranging from 1.5 to 7.8 years. One hundred and fifty-four of the implants survived, while two implants failed; 98.8% of the prostheses survived, while 75.9% were successful. Success was achieved in 90.4% of implants and in 80% of patients. The sample showed average radiographic bone resorption of 1.09 mm. The average pocket probing depth was 2.79 mm. Bleeding on probing was found in 18% of all sites, and 59.6% of implants showed bleeding on probing in at least one site. Mucositis was found in 90% of patients, and peri-implantitis was found in 16% of patients.The rates of success and survival showed the reliability of implant therapy. Plaque accumulation, smoking and upper jaw location, seem to increase the risk of failure of implant-supported rehabilitation.

Published
2018

5. Oral management of adult patients undergoing hematopoietic stem cell transplantation

Author

Bollero, P, Passarelli, Pier Carmine, D'Addona, Antonio, Pasquantonio, G, Mancini, M, Condò, R, Cerroni, L, Passarelli, P C, D'Addona, A (ORCID:0000-0002-0876-7594), Bollero, P, Passarelli, Pier Carmine, D'Addona, Antonio, Pasquantonio, G, Mancini, M, Condò, R, Cerroni, L, Passarelli, P C, and D'Addona, A (ORCID:0000-0002-0876-7594)

Abstract

Chemotherapy and hematopoietic stem cell transplantation (HSCT) are the current treatments for patients with hematological diseases; they result in myelosuppression, and increase the susceptibility of patients to severe infections. The oral cavity is a potential site of complications in HSCT patients, because it is the entrance for agents that can cause systemic infections; it is one of the most frequent locations for side effects deriving from conditioning therapy. The importance of dental pre-chemotherapy and transplant prescription is often stressed, since both therapies depress the immune system and platelets, making each intervention at this stage a high risk. The aim of this article is to review the potential complications of HSCT, and to extrapolate from the scientific literature the treatments and timeframes in which dental therapies can be performed, avoiding important risks for patients.

Published
2018

6. Clinical and radiographic assessment of implant-supported rehabilitation of partial and complete edentulism: a 2 to 8 years clinical follow-up

Author

Manicone, Paolo Francesco, Passarelli, Pc, Bigagnoli, S, Pastorino, Roberta, Manni, Armando, Pasquantonio, G, D'Addona, Antonio, Manicone PF (ORCID:0000-0003-0283-2903), Pastorino R (ORCID:0000-0001-5013-0733), Manni A (ORCID:0000-0002-7784-1911), D'Addona A (ORCID:0000-0002-0876-7594), Manicone, Paolo Francesco, Passarelli, Pc, Bigagnoli, S, Pastorino, Roberta, Manni, Armando, Pasquantonio, G, D'Addona, Antonio, Manicone PF (ORCID:0000-0003-0283-2903), Pastorino R (ORCID:0000-0001-5013-0733), Manni A (ORCID:0000-0002-7784-1911), and D'Addona A (ORCID:0000-0002-0876-7594)

Abstract

The aim of this study was to find out the rates of survival and success of implant rehabilitation, and the influence of some risk indicators on the medium- and long-term prognosis. PATIENTS AND METHODS: Of the 102 patients eligible for this study rehabilitated with dental implants during the years 2009-2015, 75 patients with 156 implants of different implant systems placed and loaded by the same team were recalled. For each subject, pocket-probing depth, bleeding on probing, plaque buildup, mobility of the fixtures, and the presence/absence of prosthetic complications were recorded. Radiographic evaluation was based on the analysis of bone levels around the fixtures, as shown by intraoral radiographs. RESULTS: The average follow-up was 4.4 years, ranging from 1.5 to 7.8 years. One hundred and fifty-four of the implants survived, while two implants failed; 98.8% of the prostheses survived, while 75.9% were successful. Success was achieved in 90.4% of implants and in 80% of patients. The sample showed average radiographic bone resorption of 1.09 mm. The average pocket probing depth was 2.79 mm. Bleeding on probing was found in 18% of all sites, and 59.6% of implants showed bleeding on probing in at least one site. Mucositis was found in 90% of patients, and peri-implantitis was found in 16% of patients. CONCLUSIONS: The rates of success and survival showed the reliability of implant therapy. Plaque accumulation, smoking and upper jaw location, seem to increase the risk of failure of implant-supported rehabilitation.

Published
2018

10. ElectroBond improves immediate dentin microtensile bond strength of two etch-and-rinse adhesives

Author

Breschi, L., Roberto Di Lenarda, Dorigo, E., Mazzoni, A., Pasquantonio, G., Ruggeri Jr, A., Saboia, V. P., Visintini, E., Vita, F., Mazzoni A, Visintini E, Vita F, Pasquantonio G, Saboia VP, Ruggeri A Jr, Di Lenarda R, Dorigo E, Breschi L., Mazzoni, A, Visintini, E, Vita, Francesca, Pasquantonio, G, Saboia, Vp, RUGGERI A., Jr, DI LENARDA, Roberto, DE STEFANO, Elettra, and Breschi, Lorenzo

Subjects
Silver Staining, Surface Properties, dentin bonding systems, electric current, TEM, microtensile, dentin, IONTOPHORESIS, TOOTH, Composite Resins, COMPARATIVE SEM, NANOLEAKAGE, SINGLE-STEP ADHESIVES, HYBRID LAYER, IN-VITRO, PERMEABILITY, CONVERSION, INTERFACE, Acid Etching, Dental, Microscopy, Electron, Transmission, Settore MED/28 - Malattie Odontostomatologiche, Tensile Strength, Materials Testing, Humans, Single-Blind Method, Dental Leakage, Dental Bonding, Electrochemical Techniques, Resin Cements, Dentin-Bonding Agents, Dentin, Stress, Mechanical
Abstract

Purpose: The aim of this study was to investigate whether an electrical device for dental adhesive application (ElectroBond) influences bonding of two-step etch-and-rinse adhesives. Materials and Methods: Human teeth were selected and cut perpendicularly to their long axis to expose middle/deep dentin. Specimens were then longitudinally sectioned into halves (experimental and control halves) to create two similar bonding substrates. Experimental halves were bonded using an ElectroBond-assisted application, while control halves were bonded with disposable sponges. The adhesives tested were Adper Scotchbond 1XT and XP-BOND. Bonded specimens were submitted to the microtensile bond strength test. Additional adhesive interfaces were prepared and processed for nanoleakage investigation involving TEM examination. Results: The microtensile bond test revealed higher values (p < 0.05) for both adhesives if ElectroBond was used during layering (55.5 +/- 7.9 IVIPa for Adper Scotchbond 1XT and 54.7 +/- 7.1 IVIPa for XP-BOND) compared to the conventional mechanical adhesive application technique (41.1 +/- 6.1 MPa for Adper Scotchbond 1XT and 38.0 +/- 7.8 MPa for XP-BOND). No difference between the two adhesives was found under the same application conditions. With electricity-assisted application, TEM micrographs revealed a significant decrease in nanoleakage expression compared to the controls. Conclusion: The use of an electric current produced by ElectroBond during the application of two-step etch-and-rinse adhesives may enhance resin impregnation, thus improving dentin hybridization. Further studies should be done to confirm that this device can similarly improve adhesive application in vivo.

Published
2009

11. Nanoleakage expression after 1-year aging of adhesives applied with ElectroBond

Author

Pasquantonio G, MAZZONI, ANNALISA, Greco C, Saboia VPA, Vita F, Falconi M, BRESCHI, LORENZO, Pasquantonio, G, Mazzoni, Annalisa, Greco, C, Saboia, Vpa, Vita, F, Falconi, M, Breschi, Lorenzo, Pasquantonio G, Mazzoni A, Greco C, Saboia VPA, Vita F, Falconi M, and Breschi L

Subjects
dentin bonding systems
Published
2008

12. Electric impulses assisted adhesive application on dentin: analysis of nanoleakage

Author

BRESCHI, LORENZO, MAZZONI, Annalisa, DI LENARDA, Roberto, Suppa P, Felline C, Pasquantonio G, Mazzotti G, Breschi L, Suppa P, Mazzoni A, Felline C, Pasquantonio G, Mazzotti G, Di Lenarda R, Breschi, Lorenzo, Suppa, P, Mazzoni, Annalisa, Felline, C, Pasquantonio, G, Mazzotti, G, and DI LENARDA, Roberto

Subjects
dentin bonding systems, dentin bonding agents
Published
2006

13. Microtensile Bond Strength of Self-etching Bonding Systems using Electric Impulses

Author

MAZZONI, Annalisa, VISINTINI, ERIKA, BRESCHI, LORENZO, Pasquantonio G, Suppa P, CONTARDO, LUCA, Mazzoni A, Pasquantonio G, Suppa P, Visintini E, Contardo L, Breschi L, Mazzoni, Annalisa, Pasquantonio, G, Suppa, P, Visintini, Erika, Contardo, Luca, and Breschi, Lorenzo

Subjects
dentin bonding systems, dentin bonding agents
Published
2005

15. The effects of host derived metalloproteinases on dentin bond and the role of MMPs inhibitors on dentin matrix degradation

Author

Longhi, M, Cerroni, L, Condo', Sg, Ariano, V, and Pasquantonio, G

Subjects
MMPs inhibitors, dentin bond, metalloproteinases, Settore MED/28 - Malattie Odontostomatologiche, Original Research Article
Abstract

The work has the objective to analyze the literature on the degradation of the adhesive interface. In particular the study is focused on the role of the metalloproteinase in the hydrolytic degradation of collagen matrix in the bonded interface. The survey will concern also the latest innovations to improve and increase the link between dentin and the restorative materials through the MMPs inhibitors.The research has been carried out in the MEDLINE database by choosing keywords as "metalloproteinases" and "dentin bond" and "degradation". In vitro studies were included in the research, excluding studies with no human and deciduous teeth. Language was limited to English.The collagenolytic enzymes in mineralized dentin have been demonstrated to have an important role in dental hard tissue pathologies, including the degradation of the hybrid layer.The preservation of the collagen matrix integrity is a key issue in the attempts to improve the dentin bonding durability.

Published
2015

17. Influence of aging on etch-and-rinse adhesives applied with ElectroBond

Author

Pasquantonio G, Cova A, MAZZONI, Annalisa, VISINTINI, ERIKA, CADENARO, MILENA, DI LENARDA, Roberto, BRESCHI, LORENZO, Pasquantonio, G, Mazzoni, Annalisa, Cova, A, Visintini, Erika, Cadenaro, Milena, DI LENARDA, Roberto, and Breschi, Lorenzo

Subjects
dentin bonding systems
Published
2007

19. Antibiotic prescribing for dental conditions: A community-based study in southern Italy

Author

Mazzaglia, G, Arcoraci, V, Blandino, G, Miragliotta, G, Schito, A, Pasquantonio, G, Nicoletti, G, Caputi, A, Mazzaglia G, Arcoraci V, Blandino G, Miragliotta G, Schito AM, Pasquantonio G, Nicoletti G, Caputi AP, Mazzaglia, G, Arcoraci, V, Blandino, G, Miragliotta, G, Schito, A, Pasquantonio, G, Nicoletti, G, Caputi, A, Mazzaglia G, Arcoraci V, Blandino G, Miragliotta G, Schito AM, Pasquantonio G, Nicoletti G, and Caputi AP

Abstract

The aim of this study was to investigate for which conditions antibiotics are being used in community dental practice, and which clinical features represent the most common reason for an antibacterial approach to the treatment of dental conditions. The study was carried out from November 1998 to June 1999. Dentists were selected according to the different areas of southern Italy, from a list provided by the Italian Society of Dentists. Out of 87 selected dentists, 33 agreed to participate and filled in 1615 questionnaires for each therapeutic intervention ending with antibiotic treatment. Analysis of data indicated that alveolar-gingival abscesses were the most commonly treated infection, accounting for 23.6% of total treatments, followed by acute periodontitis (20.6%) and disodontiasis of the 3rd molar (18.5%). Parenteral antibiotics were chosen in 7.8% of cases. Penicillins were the most commonly used group, 40.1% of total treatments, followed by macrolides (30.2%) and cephalosporins (13.4%). Moreover, penicillins were widely used for post-surgery therapy (52.1%) and disodontiasis of the 3rd molar (50.8%), while macrolides were the most commonly used group for gingivitis (44.1%) and parodontal diseases (55.0%). The choice of parenteral antibiotics was related to severe general symptoms (odds ratios [OR], 4.4; 95% CI: 2.2-9.0), pain (OR, 2.7; 95% CI: 1.2-6.1) and lymphonodal involvement (OR, 6.4; 95% CI: 2.7-15.1). In conclusion, our study demonstrates that antibiotic treatment is often based on the eradication of as many microorganisms as possible, and on the clinical assessment of the patients, rather than on any knowledge of the pathogens involved.

Published
2002

23. Bond strength of adhesives applied with an electric device

Author

Pasquantonio G, Suppa P, Tay FR, CONTARDO, LUCA, BIASOTTO, MATTEO, BRESCHI, LORENZO, Pasquantonio, G, Suppa, P, Tay, Fr, Biasotto, Matteo, Contardo, Luca, and Breschi, Lorenzo

Subjects
dentin bonding systems
Published
2005

26. Fotopolimerizzazione dei materiali resinosi: effetti termici

Author

Cerroni, L, Armellin, E, Pasquantonio, G, and Condo', Sg

Subjects
resin composite, Settore MED/28 - Malattie Odontostomatologiche, polymerization, light curing, temperature, polymerization, temperature, light curing, resin composite, light emitting diode, light emitting diode
Published
2013

27. Materiali e tecnologie odontostomatologiche per igienista dentale

Author

Paganelli, C, Gastaldi, G, Denotti, G, Piras, A, Spoto, G, Scarano, A, Petrini, M, Ferrante, M, Catapano, S, Mobilio, N, Lo Muzio, L, Baldi, M, Cicciù, D, Baldoni, M, Lauritano, D, Leonida, A, Gherlone, E, Prosper, L, Laino, A, De Santis, R, Gloria, A, Zarone, F, Sorrentino, R, Menghini, P, Merlati, G, Mortellaro, C, Sampalmieri, F, Santarelli, A, Somma, F, Marigo, L, Manzon, L, Condò, Sg, Cerroni, L, Pasquantonio, G, Condò, R, Armellin, E, Bandoni, E, Corigliano, M, Ferrari, M, Goracci, C, Schierano, Gianmario, Perotti, R, Dorigo, E, Breschi, L, Cadenaro, M, and De Santis, D.

Published
2013

28. MATERIALI E TECNOLOGIE ODONTOSTOMATOLOGICHE PER IGIENISTA DENTALE

Author

Manzon, Licia, Armellin, E, Baldi, M, Baldoni, E, Baldoni, M, Breschi, L, Cadenaro, M., Catapano, S, Cerroni, L, Cicciù, D, Condò, R, Condò, Sg, Corigliano, M, De Santis, D, De Santis, R, Denotti, G, Dorigo De Stefano, E, Ferrante, M, Ferrari, M, Gastaldi, G, Gherlone, E, Gloria, A, Goracci, C, Laino, A, Lauritano, D, Leonida, A, Lo Muzio, L, Marigo, L, Menghini, P, Merlati, G, Mobilio, N, Mortellaro, C, Paganelli, C, Pasquantonio, G, Perotti, R, Petrini, M, Piras, A, Prosper, L, Sampalmieri, F, Santarelli, A, Scarano, A, Schierano, G, Somma, F, Sorrentino, R, Spoto, G, and Zarone, F.

Published
2013

29. Oral management of adult patients undergoing hematopoietic stem cell transplantation.

Author

BOLLERO, P., PASSARELLI, P. C., D’ADDONA, A., PASQUANTONIO, G., MANCINI, M., CONDÒ, R., and CERRONI, L.

Abstract

Chemotherapy and hematopoietic stem cell transplantation (HSCT) are the current treatments for patients with hematological diseases; they result in myelosuppression, and increase the susceptibility of patients to severe infections. The oral cavity is a potential site of complications in HSCT patients, because it is the entrance for agents that can cause systemic infections; it is one of the most frequent locations for side effects deriving from conditioning therapy. The importance of dental pre-chemotherapy and transplant prescription is often stressed, since both therapies depress the immune system and platelets, making each intervention at this stage a high risk. The aim of this article is to review the potential complications of HSCT, and to extrapolate from the scientific literature the treatments and timeframes in which dental therapies can be performed, avoiding important risks for patients. [ABSTRACT FROM AUTHOR]

Published
2018

34. Materiali e Tecnologie Odontostomatologiche

Author

Paganelli, C, Gastaldi, G, Denotti, G, Piras, A, Spoto, G, Scarano, A, Petrini, M, Ferrante, M, Catapano, S, Mobilio, N, Lo Muzio, L, Baldi, M, Cicciù, D, Baldoni, M, Lauritano, D, Leonida, A, Gherlone, E, Prosper, L, Laino, A, De Santis, R, Gloria, A, Zarone, F, Sorrentino, R, Menghini, P, Merlati, G, Mortellaro, C, Sampalmieri, F, Santarelli, A, Somma, F, Marigo, L, Manzon, L, Condò, Sg, Cerroni, L, Pasquantonio, G, Condò, R, Armellin, E, Bandoni, E, Corigliano, M, Ferrari, M, Goracci, C, Schierano, Gianmario, Perotti, R, Dorigo, E, Breschi, L, Cadenaro, M, and De Santis, D.

Subjects
scienza dei materiali, implantoprotesi
Published
2011

35. Neurotrophins and their receptors in human lingual tonsil: An immunohistochemical analysis

Author

Artico, M, Bronzetti, E, Felici, L, Alicino, V, Ionta, B, Bronzetti, B, Magliulo, G, Grande, C, Zamai, L, Pasquantonio, G, and De Vincentiis, M

Subjects
Cancer Research, protein p75, human lingual tonsil, receptors, Receptors, Nerve Growth Factor, cellular immunity, macrophage, lymphocyte, brain derived neurotrophic factor, brain derived neurotrophic factor receptor, nerve growth factor, neurotrophin, neurotrophin 3, neurotrophin 3 receptor, neurotrophin 4, neurotrophin receptor, protein tyrosine kinase A, nerve growth factor receptor, article, controlled study, human, human cell, human tissue, immunohistochemistry, innervation, nervous system function, priority journal, protein expression, tongue, tonsillitis, adenoid, biosynthesis, metabolism, vascular endothelium, Adenoids, Endothelium, Vascular, Humans, Immunohistochemistry, Lymphocytes, Macrophages, Nerve Growth Factors, neurotrophins, Settore MED/28 - Malattie Odontostomatologiche, Vascular, Human lingual tonsil, Neurotrophins, Receptors, Oncology, Endothelium
Abstract

Lymphoid organs are supplied by many nerve endings associated with different kinds of cells and macrophages. The role of this innervation on the release of locally active molecules is still unclear. Lingual tonsils belong to Waldeyer's Ring, in close association with palatine tonsils and nasopharyngeal (adenoids) tonsils, thus constituting part of NALT (nasal-associated lymphoid tissue) together with the tubal tonsils and lateral pharyngeal bands. In this study, we focused our attention on the expression of some neurotrophins (NTs) and their high- and low-affinity receptors in human lingual tonsils. Light immunohistochemistry showed that human tonsillar samples were generally positive for all the NTs investigated (NGF, BDNF, NT-3, NT-4) and their receptors (TrKA, TrKB, TrKC and p75) with some different expression levels. NGF and TrKC were strongly expressed in macrophages, but weakly in lymphocytes. However, BDNF and TrKB was highly expressed in lymphocytes and weaker in macrophages. The low-affinity receptor for NGF, p75, was mainly moderately expressed in the analysed samples. These results suggest the presence of a pattern of neurotrophin innervation in the human lingual tonsil which may play a role in sustaining inflammatory conditions and in modulating a close interaction between the nervous system and the different immune cellular subtypes.

Published
2008

38. Microbiological study and scanning electron microscopic analysis of root canal wall dentin following pumped diodiumtm Nd : Yag laser irradiation

Author

D'Ercole, S, D'Arcangelo, C, Catamo, G, Prosperi, Gd, Tripodi, D, Pasquantonio, G, and Piccolomini, R

Subjects
crystallization, Actinomyces naeslundii, bacterial count, melting point, Colony Count, article, bactericidal activity, controlled study, dentin, Gram negative infection, neodymium laser, nonhuman, Pseudomonas aeruginosa, scanning electron microscopy, tooth root canal, YAG laser, Actinomyces, actinomycosis, evaluation, human, instrument sterilization, laser, methodology, microbiology, radiation exposure, tooth pulp, ultrastructure, Bacteria (microorganisms), Negibacteria, Pseudomonas, neodymium, Actinomycosis, Colony Count, Microbial, Dental Pulp Cavity, Dentin, Humans, Lasers, Microscopy, Electron, Scanning, Neodymium, Pseudomonas Infections, Sterilization, ND:YAG laser, Electron, SEM analysis, Canal sterilization, Endodontic, Irradiation, Microbial, Settore MED/28 - Malattie Odontostomatologiche, Scanning, Microscopy
Published
2004

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