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Melanoma metastasizes to the gastrointestinal tract in 2-4% of cases. In addition, it is the tumor that most frequently metastasizes to the gallbladder (50-67% of metastasis at this level). Even so, these metastases are infrequent. The indication of cholecystectomy will be provided by the patient performance status, extension and prognosis of disease. Although open surgery is preferred to treat melanoma metastasis at this level, laparoscopic surgery could be a safe technique that allows a fast recovery of the patient. We present the case of a 48-year-old man with melanoma metastases in the gallbladder treated by laparoscopic cholecystectomy.

Scientific literature presents a number of examples in which the mechanical properties of materials are significantly improved by adding small amounts of nano-particles. In many cases, the addition of such nano-particles is performed on polymer-matrix composites, with reported improvements in mechanical, optical, thermal or electrical properties. Therefore, the potential of this technology is huge and a great deal of research work is being performed with the aim of generating new advanced engineering materials. However, this paper presents the other side of the coin. The authors have introduced small amounts of Graphene Oxide (up to 1%) in PA6 with the aim of studying their effect on the fracture properties of the resulting composites. For the particular conditions analyzed here, no improvements in the fracture behavior (in both cracked and notched conditions) have been observed (a similar conclusion may be obtained for the tensile behavior). Other types of material properties were not covered in the analysis. Sharing this kind of (negative) results may save other researchers time and budget, and it is a much more common practice in other fields of science. The authors of this work would like to express their gratitude to the Spanish Ministry of Science and Innovation for the financial support of the project PGC2018-095400-B-I00 “Comportamiento en fractura de materiales compuestos nano-reforzados con defectos tipo entalla”, on the results of which this paper is based.

Resumen Paciente de 73 anos remitida por hallazgo casual de una gran masa abdominal. En la ecografia abdominal se observo una tumoracion mixta de predominio quistico que ocupaba todo el abdomen desde la pelvis hasta el apendice xifoides. La TAC abdominopelvica informo de una masa quistica que ocupaba todo el abdomen en relacion con cistoadenoma/cistoadenocarcinoma mucinoso ovarico, por lo que se indico tratamiento quirurgico, siendo el diagnostico definitivo un leiomioma dependiente de utero con degeneracion hidropica. Los miomas uterinos son tumoraciones frecuentes en la mujer; sin embargo, si presentan cambios degenerativos puede ser dificil su diagnostico inicial, al simular patologia anexial.

Trabajo de Investigación Tecnológica Con esta investigación se pretende evaluar el comportamiento que se presenta cuando una arcilla se pone en contacto con un fluido, este fenómeno se conoce como doble capa difusa, en donde la fase liquida alrededor de las partículas de arcilla forma una concentración de cationes y de agua dipolar. De acuerdo a lo anterior se realizaron los respectivos ensayos de laboratorio con diferentes tipos de arcillas y fluidos, el método que se llevó a cabo fue el de los límites de Atterberg o de consolidación según la norma INVIAS. Pregrado Ingeniero Civil

SPIB is an Ets transcription factor that is expressed exclusively in mature B cells, T-cell progenitors, and plasmacytoid dendritic cells. In the present study, we developed a novel mAb against the SPIB protein and characterized its expression in major hematolymphoid neoplasms, including a series of 45 cases of blastic plasmacytoid dendritic cell (BPDC) neoplasms and their potential cutaneous mimics. We found that SPIB is expressed heterogeneously among B- and T-cell lymphoma types. Interestingly, SPIB is expressed in a large proportion of nongerminal center type DLBCLs. In cutaneous neoplasms, SPIB is overexpressed in all BPDC neoplasms, but none of its cutaneous mimics. SPIB remains overexpressed in all cases that lack 1 or 2 of the markers used for BPDC neoplasms (ie, CD4, CD56, TCL1, and CD123). We conclude that SPIB expression can be used as a tool for diagnosing BPDC neoplasms, but it needs to be tested in conjunction with the growing arsenal of markers for human plasmacytoid dendritic cells.

Tesis (Ingeniero Electricista)-- Corporación Universitaria Autónoma de Occidente, 1983 Pregrado Ingeniero(a) Electricista