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5. Secondary impacts of the COVID-19 pandemic at a tertiary children’s hospital in Canada: a mixed-methods study

Author

Diskin, Catherine, primary, Orkin, Julia, additional, Dharmaraj, Blossom, additional, Agarwal, Tanvi, additional, Parmar, Arpita, additional, McNaughton, Kelly, additional, Cohen, Eyal, additional, Sunderji, Alia, additional, Faraoni, David, additional, Fecteau, Annie, additional, Fischer, Jason, additional, Maynes, Jason, additional, Mahant, Sanjay, additional, and Friedman, Jeremy, additional

Published
2023
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6. Total Serum Bilirubin within 3 Months of Hepatoportoenterostomy Predicts Short-Term Outcomes in Biliary Atresia

Author

Alonso, Estella, Kaurs, Elizabeth, Kelly, Sue, Bove, Kevin, Heubi, James, Miethke, Alexander, Tiao, Greg, Denlinger, Julie, Ferris, Andrea, Feldman, Amy, Mack, Cara, Suchy, Frederick, Sundaram, Shikha, Van Hove, Johan, Hite, Michelle, Kantor, Susanna, Miller, Todd, Smith, Julia, VanWinkle, Becky, Loomes, Kathleen, Lin, Henry, Piccoli, David, Russo, Pierre, Spinner, Nancy, Brown, Lindsay, Elgert, Emily, Erlichman, Jessi, Alissa, Feras, Lindblad, Douglas, Mazariegos, George, Ortiz-Aguayo, Roberto, Perlmutter, David, Sindhi, Rakesh, Venkat, Veena, Vockley, Jerry, Bukauskas, Kathy, Kufen, Adam, Schulte, Madeline, Bull, Laura, Fleck, Shannon, Langlois, Camille, Teckman, Jeffery, Kociela, Vikki, Postma, Stacy, Harris, Kathleen, Bozic, Molly, Subbarao, Girish, Byam, Beth, Klipsch, Ann, Sawyers, Cindy, Horslen, Simon, Hsu, Evelyn, Cooper, Kara, Young, Melissa, Kamath, Binita, DeAngelis, Maria, O'Connor, Constance, VanRoestel, Krista, Parmar, Arpita, Quammie, Claudia, Hung, Kelsey, Guthery, Stephen, Jensen, Kyle, Rutherford, Ann, Kerker, Nanda, Michail, Sonia, Thomas, Danny, Goodhue, Catherine, Gupta, Nikita, Vos, Mariam, de la Cruz-Tracey, Liezl, Hankerson-Dyson, Dana, Tory, Rita, Turner-Green, Taieshia, Wellons, Allison, Brandt, Mary, Finegold, Milton, Harpavat, Sanjiv, Hertel, Paula, Leung, Daniel, Liwanag, Loriel, Thompson, Richard, Brown, Sherry, Doo, Edward, Hoofnagle, Jay, Hall, Sherry, Torrance, Rebecca, Brown, Jameisha, Kafka, Kimberly, Merion, Robert, Spino, Cathie, Shneider, Benjamin L., Magee, John C., Karpen, Saul J., Rand, Elizabeth B., Narkewicz, Michael R., Bass, Lee M., Schwarz, Kathleen, Whitington, Peter F., Bezerra, Jorge A., Kerkar, Nanda, Haber, Barbara, Rosenthal, Philip, Turmelle, Yumirle P., Molleston, Jean P., Murray, Karen F., Ng, Vicky L., Wang, Kasper S., Romero, Rene, Squires, Robert H., Arnon, Ronen, Sherker, Averell H., Moore, Jeffrey, Ye, Wen, and Sokol, Ronald J.

Published
2016
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8. Longitudinal Associations Between Sleep Habits, Screen Time and Overweight, Obesity in Preschool Children

Author

Reyna-Vargas, Myrtha E, primary, Parmar, Arpita, additional, Lefebvre, Diana L, additional, Azad, Meghan B, additional, Becker, Allan B, additional, Turvey, Stuart E, additional, Moraes, Theo J, additional, Lou, Wendy, additional, Subbarao, Padmaja, additional, Sears, Malcolm R, additional, Mandhane, Piushkumar J, additional, and Narang, Indra, additional

Published
2022
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9. Longitudinal Associations Between Sleep Habits, Screen Time and Overweight, Obesity in Preschool Children

Author

Reyna-Vargas,Myrtha E, Parmar,Arpita, Lefebvre,Diana L, Azad,Meghan B, Becker,Allan B, Turvey,Stuart E, Moraes,Theo J, Lou,Wendy, Subbarao,Padmaja, Sears,Malcolm R, Mandhane,Piushkumar J, Narang,Indra, Reyna-Vargas,Myrtha E, Parmar,Arpita, Lefebvre,Diana L, Azad,Meghan B, Becker,Allan B, Turvey,Stuart E, Moraes,Theo J, Lou,Wendy, Subbarao,Padmaja, Sears,Malcolm R, Mandhane,Piushkumar J, and Narang,Indra

Abstract

Myrtha E Reyna-Vargas,1 Arpita Parmar,2 Diana L Lefebvre,3 Meghan B Azad,4– 6 Allan B Becker,4,5 Stuart E Turvey,7 Theo J Moraes,1 Wendy Lou,8 Padmaja Subbarao,1,8 Malcolm R Sears,3 Piushkumar J Mandhane,9 Indra Narang1,10 1Translational Medicine Program, The Hospital for Sick Children, Toronto, ON, Canada; 2Sculich School of Medicine and Dentistry, Western University, London, ON, Canada; 3Department of Medicine, McMaster University, Hamilton, ON, Canada; 4Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada; 5Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Children’s Hospital, Winnipeg, MB, Canada; 6Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada; 7Department of Pediatrics, BC Children’s Hospital, University of British Columbia, Vancouver, BC, Canada; 8Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; 9Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; 10Faculty of Medicine, University of Toronto, Toronto, ON, CanadaCorrespondence: Indra Narang, The Hospital for Sick Children, 555 University Ave-Hill Wing Room #4534, Toronto, ON, M5G 1X8, Canada, Email indra.narang@sickkids.caIntroduction: Decreased sleep duration and increased screen time as early as preschool age may contribute to overweight and obesity. The effects of bedtime together with nocturnal sleep duration remain unclear with a paucity of data evaluating these associations longitudinally. We aim to evaluate the independent and joint effects of sleep duration, sleep bedtime, and screen time at 3 years of age on BMI status, particularly overweight and obesity by age 5 years.Methods: Data from 2185 participants of the CHILD Cohort Study were analyzed longitudinally using generalized estimating equations (GEE). Models included changes in overweight/obesity status from 3 to 5 years of age as outcome, and nocturnal sleep duration, bedtime, and dail

Published
2022

12. Disruptions in Care: Consequences of the COVID-19 Pandemic in a Children’s Hospital

Author

Diskin, Catherine, primary, Orkin, Julia, additional, Dharmaraj, Blossom, additional, Agarwal, Tanvi, additional, Parmar, Arpita, additional, Naughton, Kelly Mc, additional, Cohen, Eyal, additional, Sunderji, Alia, additional, Faraoni, David, additional, Fecteau, Annie, additional, Fischer, Jason, additional, Maynes, Jason, additional, Mahant, Sanjay, additional, and Friedman, Jeremy N, additional

Published
2021
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17. Coached, Coordinated, Enhanced Neonatal Transition (CCENT): protocol for a multicentre pragmatic randomised controlled trial of transition-to-home support for parents of high-risk infants

Author

Orkin, Julia, primary, Major, Nathalie, additional, Esser, Kayla, additional, Parmar, Arpita, additional, Couture, Elise, additional, Daboval, Thierry, additional, Kieran, Emily, additional, Ly, Linh, additional, O'Brien, Karel, additional, Patel, Hema, additional, Synnes, Anne, additional, Robson, Kate, additional, Barreira, Lesley, additional, Smith, Wanda L, additional, Rizakos, Sara, additional, Willan, Andrew R, additional, Yaskina, Maryna, additional, Moretti, Myla E, additional, Ungar, Wendy J, additional, Ballantyne, Marilyn, additional, Church, Paige Terrien, additional, and Cohen, Eyal, additional

Published
2021
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21. Narcolepsy Treatment: Voices of Adolescents.

Author

Xiao, Lena, Chen, Anna, Parmar, Arpita, Frankel, Lucy, Toulany, Alene, Murray, Brian J., and Narang, Indra

Subjects
NARCOLEPSY, TEENAGERS, SOCIAL support, SLEEP disorders, CATAPLEXY, TEENAGE girls
Abstract

Narcolepsy, characterized by excessive daytime sleepiness, is a debilitating lifelong sleep disorder for which there is no cure. Current pharmacological and nonpharmacological treatments directed toward symptom management may be suboptimal. This qualitative study explores the perspective of adolescents on therapeutic interventions for narcolepsy. Semi-structured interviews with adolescents with narcolepsy were conducted from May to August 2019 at The Hospital for Sick Children in Toronto, Canada. Qualitative thematic analysis was utilized to generate themes emerging from the data. Eighteen adolescents with narcolepsy (age range = 10–17, mean age = 14.4 ± 2.0 years, 72% male) participated and 56% had cataplexy. Four prominent themes arose regarding therapeutic interventions for narcolepsy. Firstly, participants described that pharmacotherapy was moderately effective but did not fully relieve symptoms associated with narcolepsy. Secondly, while medications are the first line treatment for narcolepsy, many participants reported frustration regarding medication dependence and side effects. Thirdly, nonpharmacological strategies including scheduled sleep times and exercise were accepted and often employed. Lastly, adolescents desired more psychosocial support to address mental health sequelae of narcolepsy that were not fully managed by current treatment modalities. Medications were perceived as moderately effective for managing narcolepsy but almost all participants expressed concerns with taking medications due to side effects. Adolescents valued the importance of more holistic care for their narcolepsy treatment such as psychosocial support and nonpharmacological modalities. Further anticipatory guidance regarding pharmacological side effect profiles and better integration with nonpharmacological modalities are needed to improve disease control in adolescent patients. [ABSTRACT FROM AUTHOR]

Published
2022
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23. Living with narcolepsy during adolescence: A qualitative study

Author

Chen, Anna, Parmar, Arpita, Naik, Tanvi, Hutchinson, Crystal, Frankel, Lucy, Zweerink, Allison, Murray, Brian J., Toulany, Alene, and Narang, Indra

Abstract

AbstractRATIONALE: Narcolepsy is a chronic sleep disorder, with typical onset in childhood or adolescence. Features of narcolepsy include excessive daytime sleepiness (EDS), cataplexy, sleep paralysis, hallucinations and disturbed nocturnal sleep. The constellation of symptoms may be challenging for patients to manage. Adolescents with narcolepsy report poor quality of life and mental health concerns.OBJECTIVE: The objective of this report was to understand the experience of living with narcolepsy as an adolescent and its impact on daily functioning, relationships and mental health.METHODS: In-depth, semistructured interviews with adolescents with narcolepsy were conducted from May to August 2019 at the Hospital for Sick Children in Toronto, Canada. Interview questions focused on perceptions of 1) disease symptoms, 2) mental health, 3) daily functioning, 4) relationships and 5) coping. Interviews were digitally audio-recorded for verbatim transcription, coded by two researchers and analyzed using NVivo qualitative data computer software.RESULTS: Eighteen adolescents with narcolepsy (age range = 10-17, mean age = 14.4 ± 2.0, 72.2% male) participated. The findings suggest some of the common symptoms of narcolepsy (eg, EDS) are often experienced as unpleasant, while vivid dreaming may be pleasant. Emotional challenges such as frustration with symptoms and worries about the future are common. Participants emphasize the importance of ongoing support from others (eg, clinical team, teachers) to help with coping with chronic illness.CONCLUSION: Living with narcolepsy poses unique challenges for adolescents and impacts their psychosocial health. We recommend increased psychosocial support from mental health professionals, educational resources for schools and teachers, and peer support groups for adolescent narcolepsy patients.

Published
2022
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25. Health-related quality of life in pre-adolescent liver transplant recipients with biliary atresia: A cross-sectional study

Author

Miserachs, Mar, primary, Parmar, Arpita, additional, Bakula, Agnieszka, additional, Hierro, Loreto, additional, D’Antiga, Lorenzo, additional, Goldschmidt, Imeke, additional, Debray, Dominique, additional, A McLin, Valérie, additional, Casotti, Valeria, additional, Pawłowska, Joanna, additional, Camarena, Carmen, additional, R Otley, Anthony, additional, Baumann, Ulrich, additional, and L Ng, Vicky, additional

Published
2019
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28. Family functioning among adolescents with narcolepsy

Author

Parmar, Arpita, primary, Yeh, Eluen Ann, additional, Korczak, Daphne J, additional, Weiss, Shelly K, additional, Lu, Zihang, additional, Zweerink, Allison, additional, Toulany, Alene, additional, Murray, Brian J, additional, and Narang, Indra, additional

Published
2019
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29. Caregiver support and positive airway pressure therapy adherence among adolescents with obstructive sleep apnea.

Author

Parmar, Arpita, Messiha, Sandra, Baker, Adele, Zweerink, Allison, Toulany, Alene, and Narang, Indra

Subjects
*SLEEP apnea syndrome treatment, *SERVICES for caregivers, *PATIENT compliance, *TIME, *BODY mass index, *RETROSPECTIVE studies, *CONTINUOUS positive airway pressure, *DESCRIPTIVE statistics, *ADOLESCENCE
Abstract

Introduction Positive airway therapy (PAP) adherence rates are suboptimal among adolescents with obstructive sleep apnea (OSA) and strategies to increase PAP adherence is a clinical priority. This study evaluates if caregiver support is associated with PAP adherence rates among adolescents with OSA. Methods We conducted a retrospective study and evaluated PAP adherence rates among adolescents with OSA from 2012 to 2017. Adherence was measured as continuous variables: average PAP usage (minutes per night) and average PAP usage >4 hours/night (% of all nights). We evaluated if adolescents with OSA who were receiving practical caregiver support with PAP had higher adherence than adolescents with OSA without caregiver support. Results One hundred and seven adolescents with OSA (mean age=14.1±2.5 years, 64.5% male, mean BMI percentile=89.0±21.8) seen between January 2012 and August 2017 at our institution were included. In this study, 60.7% (n=65) of adolescents with OSA were receiving practical caregiver support with PAP therapy. Adolescents with OSA receiving practical caregiver support with PAP used therapy for a significantly greater duration each night compared to adolescents who were not receiving practical caregiver support (298.5±206.7 versus 211.9±187.2 minutes; P=0.02). Greater time since the initial PAP prescription was independently associated with PAP adherence. Conclusion Focusing on PAP adherence early may help adolescents with OSA incorporate therapy into their nightly routine, which may improve adherence and lead to improved health outcomes in adolescents with OSA. Practical caregiver support may be an essential component of ensuring optimal PAP adherence among adolescents with OSA. [ABSTRACT FROM AUTHOR]

Published
2020
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32. Design and Implementation of Novel Wavelet Approach for Improving Quality of Medical Images

Author

Nishant N Parmar, G Parmar Arpita, and R Jadav Kalpesh

Subjects
Discrete wavelet transform, Image fusion, business.industry, Computer science, media_common.quotation_subject, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Wavelet transform, Image processing, Wavelet, Wavelet approach, Medical imaging, Computer vision, Quality (business), Artificial intelligence, business, media_common
Abstract

In Image Processing Quality and Quantity of the any images are basic parameters, in medical science it is too much difficult to evaluate soft tissues and hard tissues simultaneously. Multimodal image fusion is the solution for merging complimentary information. Wavelet based approach in this paper describes an algorithm to improve the quality of medical images. Hybridization of SWT and PCA method gives best result.

Published
2015

33. Total Serum Bilirubin within 3 Months of Hepatoportoenterostomy Predicts Short-Term Outcomes in Biliary Atresia

Author

Shneider, Benjamin L., primary, Magee, John C., additional, Karpen, Saul J., additional, Rand, Elizabeth B., additional, Narkewicz, Michael R., additional, Bass, Lee M., additional, Schwarz, Kathleen, additional, Whitington, Peter F., additional, Bezerra, Jorge A., additional, Kerkar, Nanda, additional, Haber, Barbara, additional, Rosenthal, Philip, additional, Turmelle, Yumirle P., additional, Molleston, Jean P., additional, Murray, Karen F., additional, Ng, Vicky L., additional, Wang, Kasper S., additional, Romero, Rene, additional, Squires, Robert H., additional, Arnon, Ronen, additional, Sherker, Averell H., additional, Moore, Jeffrey, additional, Ye, Wen, additional, Sokol, Ronald J., additional, Alonso, Estella, additional, Kaurs, Elizabeth, additional, Kelly, Sue, additional, Bove, Kevin, additional, Heubi, James, additional, Miethke, Alexander, additional, Tiao, Greg, additional, Denlinger, Julie, additional, Ferris, Andrea, additional, Feldman, Amy, additional, Mack, Cara, additional, Suchy, Frederick, additional, Sundaram, Shikha, additional, Van Hove, Johan, additional, Hite, Michelle, additional, Kantor, Susanna, additional, Miller, Todd, additional, Smith, Julia, additional, VanWinkle, Becky, additional, Loomes, Kathleen, additional, Lin, Henry, additional, Piccoli, David, additional, Russo, Pierre, additional, Spinner, Nancy, additional, Brown, Lindsay, additional, Elgert, Emily, additional, Erlichman, Jessi, additional, Alissa, Feras, additional, Lindblad, Douglas, additional, Mazariegos, George, additional, Ortiz-Aguayo, Roberto, additional, Perlmutter, David, additional, Sindhi, Rakesh, additional, Venkat, Veena, additional, Vockley, Jerry, additional, Bukauskas, Kathy, additional, Kufen, Adam, additional, Schulte, Madeline, additional, Bull, Laura, additional, Fleck, Shannon, additional, Langlois, Camille, additional, Teckman, Jeffery, additional, Kociela, Vikki, additional, Postma, Stacy, additional, Harris, Kathleen, additional, Bozic, Molly, additional, Subbarao, Girish, additional, Byam, Beth, additional, Klipsch, Ann, additional, Sawyers, Cindy, additional, Horslen, Simon, additional, Hsu, Evelyn, additional, Cooper, Kara, additional, Young, Melissa, additional, Kamath, Binita, additional, DeAngelis, Maria, additional, O'Connor, Constance, additional, VanRoestel, Krista, additional, Parmar, Arpita, additional, Quammie, Claudia, additional, Hung, Kelsey, additional, Guthery, Stephen, additional, Jensen, Kyle, additional, Rutherford, Ann, additional, Kerker, Nanda, additional, Michail, Sonia, additional, Thomas, Danny, additional, Goodhue, Catherine, additional, Gupta, Nikita, additional, Vos, Mariam, additional, de la Cruz-Tracey, Liezl, additional, Hankerson-Dyson, Dana, additional, Tory, Rita, additional, Turner-Green, Taieshia, additional, Wellons, Allison, additional, Brandt, Mary, additional, Finegold, Milton, additional, Harpavat, Sanjiv, additional, Hertel, Paula, additional, Leung, Daniel, additional, Liwanag, Loriel, additional, Thompson, Richard, additional, Brown, Sherry, additional, Doo, Edward, additional, Hoofnagle, Jay, additional, Hall, Sherry, additional, Torrance, Rebecca, additional, Brown, Jameisha, additional, Kafka, Kimberly, additional, Merion, Robert, additional, and Spino, Cathie, additional

Published
2016
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