270 results on '"Parlato, Rosanna"'
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2. Nucleolar stress controls mutant Huntington toxicity and monitors Huntington’s disease progression
3. Queuosine‐tRNA promotes sex‐dependent learning and memory formation by maintaining codon‐biased translation elongation speed
4. RNA Polymerase 1 Is Transiently Regulated by Seizures and Plays a Role in a Pharmacological Kindling Model of Epilepsy
5. T cell expansion is regulated by mutual regulation of ribosome biosynthesis and mTORC1 activity
6. Cav2.3 channels contribute to dopaminergic neuron loss in a model of Parkinson’s disease
7. C9orf72-associated neurodegeneration in ALS-FTD: breaking new ground in ribosomal RNA and nucleolar dysfunction
8. Deep learning-based image-analysis identifies a DAT-negative subpopulation of dopaminergic neurons in the lateral Substantia nigra.
9. Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism
10. Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase, modulates glycosphingolipid metabolism and results therapeutically effective in experimental models of Huntington’s disease
11. Deep learning-based image-analysis identifies a DAT-negative subpopulation of dopaminergic neurons in the lateral Substantia nigra
12. A36 Neuropathological function of the TANK1-binding kinase 1 (TBK1) in mouse models of Huntington’s disease
13. I18 Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase (SGPL1), modulates glycosphingolipid metabolism and results therapeutically effective in a mouse model of Huntington’s disease
14. I19 The defective metabolism of polysialic acid (polysia) may represent an effective therapeutic target in hd pre-clinical models
15. I08 Passive immunization, with the anti-huntingtin aggregate antibody EM48, is beneficial in R6/2 mouse model
16. Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling
17. ALS ‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function
18. Genetic lesions of the noradrenergic system trigger induction of oxidative stress and inflammation in the ventral midbrain
19. Oxidative Stress in Neurodegenerative Diseases
20. Oxidative Stress in Neurodegenerative Diseases
21. Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress
22. Nucleolar activity in neurodegenerative diseases: a missing piece of the puzzle?
23. Nucleolar stress controls mutant Huntingtin toxicity and monitors Huntington’s disease progression
24. Targeted depletion of primary cilia in dopaminoceptive neurons in a preclinical mouse model of Huntington’s disease
25. Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome
26. Nucleolar stress induces a senescence-like phenotype in smooth muscle cells and promotes development of vascular degeneration
27. An integrated regulatory network controlling survival and migration in thyroid organogenesis
28. Cell Loss and Autophagy in the Extra-Adrenal Chromaffin Organ of Zuckerkandl are Regulated by Glucocorticoid Signalling
29. Editorial: Emerging Cellular Stress Sensors in Neurological Disorders: Closing in on the Nucleolus and the Primary Cilium
30. Structural Fuzziness of the RNA-Organizing Protein SERF Determines a Toxic Gain-of-interaction
31. Effects of the cell type-specific ablation of the cAMP-responsive transcription factor in noradrenergic neurons on locus coeruleus firing and withdrawal behavior after chronic exposure to morphine
32. Targeted Depletion of Primary Cilia in Dopaminoceptive Neurons in a Preclinical Mouse Model of Huntington’s Disease
33. In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species
34. Conditional Inactivation of Glucocorticoid Receptor Gene in Dopamine-β-Hydroxylase Cells Impairs Chromaffin Cell Survival
35. Regulation of neural migration by the CREB/CREM transcription factors and altered Dab1 levels in CREB/CREM mutants
36. Depolarization promotes GAD 65-mediated GABA synthesis by a post-translational mechanism in neural stem cell-derived neurons
37. Integration of the deacetylase SIRT1 in the response to nucleolar stress:metabolic implications for neurodegenerative diseases
38. Analysis of dopamine transporter gene expression pattern − generation of DAT-iCre transgenic mice
39. Requirement of the forkhead gene Foxe1, a target of sonic hedgehog signaling, in hair follicle morphogenesis
40. A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice
41. Structural fuzziness of the RNA-organizing protein SERF1a determines a toxic gain-of-interaction
42. Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases
43. rRNA and tRNA Bridges to Neuronal Homeostasis in Health and Disease
44. A Preservation Method That Allows Recovery of Intact RNA from Tissues Dissected by Laser Capture Microdissection
45. Expression of Cre recombinase in dopaminoceptive neurons
46. Nucleolar activity in neurodegenerative diseases
47. A09 Stage- and cell-specific changes of nucleolar activity and integrity are associated with the progression of huntington’s disease
48. 806 A circulus vitiosus causes loss of proteostasis in Cockayne syndrome
49. Selektive Degeneration dopaminerger Neurone beim Parkinson-Syndrom: die zunehmende Rolle von veränderter Kalziumhomöostase und nukleolärer Funktion
50. Selective degeneration of dopamine neurons in Parkinson’s disease: emerging roles of altered calcium homeostasis and nucleolar function
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