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6. Computational Methods for Improving the Observability of Platform-Based Advertising.

Author

Angus, Daniel, Hayden, Lauren, Obeid, Abdul Karim, Tan, Xue Ying, Carah, Nicholas, Burgess, Jean, Parker, Christine, Andrejevic, Mark, Fordyce, Robbie, Cellard, Loup, and Bagnara, Julian

Subjects
DIGITAL media, PLUG-ins (Computer programs), DATA libraries, DIGITAL technology, BUSINESS models
Abstract

The advertising ecosystem has been progressively reshaped by computational advertising models facilitated and controlled by digital media platforms. Meta and Alphabet, two of the dominant players in this ecosystem, have contributed significantly to industry disintermediation via the design and market dominance of their advertising systems, which in turn are symbiotic with their own business models, and feed on large amounts of consumer data generated by everyday platform use. The operations and impacts of these systems remain opaque and difficult to observe. Responding to this challenge, we present a methodological framework integrating cultural, legal, media, and computational perspectives to enable the observation of computational advertising. This methodology comprises three novel computational methods: direct data gathering from ad transparency libraries; automated data donation via participatory citizen science browser plug-ins; and a privacy-aware mobile screen capture app. We describe how our suite of computational approaches enables scalable and participant-situated research, overcoming limitations posed by restricted platform access to computational advertising data. Ethical considerations and practical implications are discussed alongside case study findings, further demonstrating the potential for these methods to inform regulatory debates and scholarly advancements in the field. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Practitioner research

Author

Parker, Christine, primary, Francis, Laura, additional, Yung, Lisa, additional, Stinson, Laura, additional, and Dean, Angela, additional

Published
2023
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13. Conclusion

Author

Clare, Sandra, primary, Parker, Christine, additional, Benford, Joanne, additional, Griffiths, Caroline, additional, Griffiths-Murru, Antonio, additional, and Clark, Katherine, additional

Published
2023
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15. Leadership

Author

Parker, Christine, primary, Khan, Anam, additional, Knowles, Laura, additional, Dumbell, Jade, additional, and Richardson, Mandy, additional

Published
2023
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23. Quantitative Imaging of Regional Cerebral Protein Synthesis in Clinical Alzheimer's Disease by [11C]Leucine PET.

Author

Herholz, Karl, McMahon, Adam, Thompson, Jennifer C., Jones, Matthew, Boutin, Herve, Gregory, Jamil, Parker, Christine A., and Hinz, Rainer

Subjects
POSITRON emission tomography, PROTEIN synthesis, ALZHEIMER'S disease, ALZHEIMER'S patients, MEDIAN (Mathematics)
Abstract

Purpose: Protein synthesis is essential to maintain integrity and function of the human brain, and protein synthesis is associated specifically with the formation of long-term memory. Experimental and clinical observations indicate that this process is disturbed in Alzheimer's dementia and other neurodegenerative diseases. In-vivo investigation with positron emission tomography (PET) using [11C]leucine provides a unique possibility to measure regional cerebral protein synthesis (rCPS) rates in human brain and to determine whether it is altered in Alzheimer's disease (AD), and thus may provide a target for future therapeutic interventions. Procedures: In this first human study, we measured rCPS by [11C]leucine PET in four patients with AD (age 57–73 years) and compared the results with six healthy controls (three of whom were age matched and the other three were young controls). Quantification of rCPS also required measurement of amino acid (AA) levels and of free and protein-bound [11C]leucine in plasma during the 90 min PET scans conducted following at least six hours of fasting. Results: Rates of rCPS measured in absolute units of nmol/g/min ranged between 1.81 and 2.53 in AD patients, 2.10 and 2.54 in matched controls, and 2.21 to 2.35 in the young controls. Mean and median values did not show significant differences between the groups. Rates of rCPS also depended upon whether corrections for plasma AA levels were included in the calculations. When considering regional values relative to the corpus callosum as a reference region, there was a tendency towards impairment of rCPS in patients, which was most prominent in the parietal cortex, but did not reach significance. Similar findings were observed with normalisation of rCPS to global cortical mean. Conclusions: In summary, this first human study assessing regional protein synthesis with [11C]leucine in AD has demonstrated where the sources of variance in measurements of cerebral protein synthesis may arise, along with the potential magnitude of this variance. This study also indicates that there is a tendency towards impairment of rCPS in patients with Alzheimer's disease, which requires further investigation including possible partial volume effects due to atrophy. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals

Author

Livingston, Nicholas R., Calsolaro, Valeria, Hinz, Rainer, Nowell, Joseph, Raza, Sanara, Gentleman, Steve, Tyacke, Robin J., Myers, Jim, Venkataraman, Ashwin V., Perneczky, Robert, Gunn, Roger N., Rabiner, Eugenii A., Parker, Christine A., Murphy, Philip S., Wren, Paul B., Nutt, David J., Matthews, Paul M., and Edison, Paul

Published
2022
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27. Children first

Author

Parker, Christine, primary, Austin, Zoë, additional, and Griffiths-Murru, Antonio, additional

Published
2022
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30. A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index

Author

Wlazly, Dominika, Dickinson, Amber, Foster, Andy, Knight, Clare, Leckey, Claire, Morgan, Paul, Morgan, Angharad, O'Hagan, Caroline, Touchard, Samuel, Khan, Shahid, Murphy, Phil, Parker, Christine, Patel, Jai, Richardson, Jill, Acton, Paul, Austin, Nigel, Bhattacharya, Anindya, Carruthers, Nick, de Boer, Peter, Drevets, Wayne, Isaac, John, Jones, Declan, Kemp, John, Kolb, Hartmuth, Nye, Jeff, Wittenberg, Gayle, Barker, Gareth, Bogdanova, Anna, Byrom, Heidi, Cash, Diana, Cattaneo, Annamaria, Enache, Daniela, Gee, Tony, Hastings, Caitlin, Kose, Melisa, Lombardo, Giulia, Mariani, Nicole, McLaughlin, Anna, Mondelli, Valeria, Nettis, Maria, Nikkheslat, Naghmeh, Pariante, Carmine, Randall, Karen, Schubert, Julia, Sforzini, Luca, Sheridan, Hannah, Simmons, Camilla, Singh, Nisha, Turkheimer, Federico, Van Loo, Vicky, Veronese, Mattia, Rodriguez, Marta Vicente, Wood, Toby, Worrell, Courtney, Zajkowska, Zuzanna, Campbell, Brian, Egebjerg, Jan, Eriksson, Hans, Gastambide, Francois, Adams, Karen Husted, Jeggo, Ross, Moeller, Thomas, Nelson, Bob, Plath, Niels, Thomsen, Christian, Pederson, Jan Torleif, Zorn, Stevin, Deith, Catherine, Farmer, Scott, McClean, John, McPherson, Andrew, Penandes, Nagore, Scouller, Paul, Sutherland, Murray, Attenburrow, Mary Jane, Benjamin, Jithen, Jones, Helen, Mada, Fran, Oladejo, Akintayo, Smith, Katy, Balice-Gordon, Rita, Binneman, Brendon, Duerr, James, Fullerton, Terence, Goli, Veeru, Hughes, Zoe, Piro, Justin, Samad, Tarek, Sporn, Jonathan, Hoskins, Liz, Kohn, Charmaine, Wilcock, Lauren, Aigbirhio, Franklin, Bhatti, Junaid, Bullmore, Ed, Chamberlain, Sam, Correia, Marta, Crofts, Anna, Fryer, Tim, Graves, Martin, Hatton, Alex, Kitzbichler, Manfred, Lynall, Mary-Ellen, Maurice, Christina, O'Donnell, Ciara, Pointon, Linda, St George Hyslop, Peter, Turner, Lorinda, Vertes, Petra, Widmer, Barry, Williams, Guy, Cavanagh, Jonathan, McColl, Alison, Shaw, Robin, Boddeke, Erik, Baird, Alison, Clare, Stuart, Cowen, Phil, Huang, I-Shu (Dante), Hurley, Sam, Lovestone, Simon, Nevado-Holgado, Alejo, Ribe, Elena, Vyas, Anviti, Winchester, Laura, Cleal, Madeleine, Gomez-Nicola, Diego, Mancuso, Renzo, Perry, Hugh, Cercignani, Mara, Clarke, Charlotte, Colasanti, Alessandro, Harrison, Neil, Murray, Rosemary, O'Connor, Jason, Mount, Howard, Schubert, Julia J., Fryer, Tim D., Manavaki, Roido, Kitzbichler, Manfred G., Nettis, Maria A., Pariante, Carmine M., Bullmore, Edward T., and Turkheimer, Federico E.

Published
2021
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31. Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using 11C-BU99008 PET and its relationship with amyloid load

Author

Calsolaro, Valeria, Matthews, Paul M., Donat, Cornelius K., Livingston, Nicholas R., Femminella, Grazia D., Guedes, Sandra Silva, Myers, Jim, Fan, Zhen, Tyacke, Robin J., Venkataraman, Ashwin V., Perneczky, Robert, Gunn, Roger, Rabiner, Eugenii A., Gentleman, Steve, Parker, Christine A., Murphy, Philip S., Wren, Paul B., Hinz, Rainer, Sastre, Magdalena, Nutt, David J., and Edison, Paul

Published
2021
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36. The Feasibility and Impact of a Presurgical Exercise Intervention Program (Prehabilitation) for Patients Undergoing Cystectomy for Bladder Cancer

Author

Kaye, Deborah R., Schafer, Christine, Thelen-Perry, Steven, Parker, Christine, Iglay-Reger, Heidi, Daignault-Newton, Stephanie, Qin, Yongmei, Morgan, Todd M., Weizer, Alon Z., Kaffenberger, Samuel D., Herrel, Lindsey A., Hafez, Khaled S., Lee, Cheryl T., Skolarus, Ted A., Englesbe, Michael J., and Montgomery, Jeffrey S.

Published
2020
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39. Frederick Douglass: Ten Days of a Fugitive Slave in Buffalo

Author

Parker, Christine A.

Subjects
Buffalo, New York -- History, Douglass, Frederick -- Biography, Fugitive slaves -- Biography, Ethnic, cultural, racial issues/studies, History
Abstract

This year, the nation will commemorate the 200 birthday of Frederick Augustus Washington Bailey, better know as Frederick Douglass. Frederick Douglass was born into slavery in Maryland, and despite a [...]

Published
2020

40. Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study)

Author

Lukey, Pauline T., Coello, Christopher, Gunn, Roger, Parker, Christine, Wilson, Frederick J., Saleem, Azeem, Garman, Nadia, Costa, Maria, Kendrick, Stuart, Onega, Mayca, Kang’ombe, Arthur R., Listanco, Allan, Davies, James, Ramada-Magalhaes, Joaquim, Moz, Sara, Fahy, William A., Maher, Toby M., Jenkins, Gisli, Passchier, Jan, and Marshall, Richard P.

Published
2020
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41. Preclinical evaluation of [18F]FB-A20FMDV2 as a selective marker for measuring αVβ6 integrin occupancy using positron emission tomography in rodent lung

Author

Onega, Mayca, Parker, Christine A., Coello, Christopher, Rizzo, Gaia, Keat, Nicholas, Ramada-Magalhaes, Joaquim, Moz, Sara, Tang, Sac-Pham, Plisson, Christophe, Wells, Lisa, Ashworth, Sharon, Slack, Robert J., Vitulli, Giovanni, Wilson, Frederick J., Gunn, Roger, Lukey, Pauline T., and Passchier, Jan

Published
2020
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43. Utopias, magic realism and rebellious spirits : films of Christine Parker 1990 to 2000

Author

Templeton-Parker, Christine

Subjects
791.43, One Man’s Meat, Peach, Lucy Lawless, Hinekaro, Keri Hulme, New Zealand film, Channelling Baby, women in film, Maori in film, neoliberalism, identity, entitlement, empowerment, free market fundamentalism
Abstract

“The More You Look, the more THERE IS to see…” From Hinekaro Goes on a Picnic and Blows up Another Obelisk (Christine Parker, Oceania Parker, 1995) In the 1990s New Zealand was in the grip of free market fundamentalism, neo-liberal deregulation of the economy having begun in the mid-eighties. The Maori protest movement was a major source of societal conflict and feminism had become the ‘F’ word. This study examines my writing and directing during the 1990s in New Zealand. It is proposed that the films contributed to national and international conversations around feminism, colonial struggles, spirituality and the supernatural. It is argued that these works offer a social critique of neoliberalism and the divisive effects of it, on women in particular. In the context of this appraisal neoliberalism is understood to be a set of beliefs that support the functioning of the global free market, with minimal government regulation, except to protect the functioning of private enterprise and the ownership of private property. The short films One Man’s Meat (1991), Peach (1993), and Hinekaro Goes on a Picnic and Blows up Another Obelisk (1995) and the feature film Channelling Baby (1999) are located in an oeuvre of female, Gay, and Maori film makers and artists responding to this environment. The recurrence of alternative utopias, the use of magic realism and the representation of the spiritual and supernatural in my work are also considered in relation to other films made in the period. A case is made that the films were part of a small vanguard of films responding to the 1990s status quo by offering alternative modes of discourse to the dominant economic rationalism. Rich in visual intensity and heightened narrative tropes, such as irony and fragmented narratives, my aesthetic choices, together with recurring themes of chance and fate, agency and identity, are considered to link the films together as a coherent study. While the works are located in an evolving feminist tradition in the 1990s, their continued relevance today, particularly in relation to foregrounding marginal voices and the disruption of dominant paradigms and expectations of female behaviour and identity, underpin the claim for originality.

Published
2015
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45. Inflammatory biomarkers in Alzheimer's disease plasma

Author

Bullmore, Edward T., Bhatti, Junaid, Chamberlain, Samuel J., Correia, Marta M., Crofts, Anna L., Dickinson, Amber, Foster, Andrew C., Kitzbichler, Manfred G., Knight, Clare, Lynall, Mary-Ellen, Maurice, Christina, O'Donnell, Ciara, Pointon, Linda J., St George Hyslop, Peter, Turner, Lorinda, Vertes, Petra, Widmer, Barry, Williams, Guy B., Morgan, B. Paul, Leckey, Claire A., Morgan, Angharad R., O'Hagan, Caroline, Touchard, Samuel, Cavanagh, Jonathan, Deith, Catherine, Farmer, Scott, McClean, John, McColl, Alison, McPherson, Andrew, Scouller, Paul, Sutherland, Murray, Boddeke, H.W.G.M., Richardson, Jill C., Khan, Shahid, Murphy, Phil, Parker, Christine A., Patel, Jai, Jones, Declan, de Boer, Peter, Kemp, John, Drevets, Wayne C., Nye, Jeffrey S., Wittenberg, Gayle, Isaac, John, Bhattacharya, Anindya, Carruthers, Nick, Kolb, Hartmuth, Pariante, Carmine M., Turkheimer, Federico, Barker, Gareth J., Byrom, Heidi, Cash, Diana, Cattaneo, Annamaria, Gee, Antony, Hastings, Caitlin, Mariani, Nicole, McLaughlin, Anna, Mondelli, Valeria, Nettis, Maria, Nikkheslat, Naghmeh, Randall, Karen, Sheridan, Hannah, Simmons, Camilla, Singh, Nisha, Van Loo, Victoria, Vicente-Rodriguez, Marta, Wood, Tobias C., Worrell, Courtney, Zajkowska, Zuzanna, Plath, Niels, Egebjerg, Jan, Eriksson, Hans, Gastambide, Francois, Adams, Karen Husted, Jeggo, Ross, Thomsen, Christian, Pederson, Jan Torleif, Campbell, Brian, Möller, Thomas, Nelson, Bob, Zorn, Stevin, O'Connor, Jason, Attenburrow, Mary Jane, Baird, Alison, Benjamin, Jithen, Clare, Stuart, Cowen, Philip, Huang, I-Shu (Dante), Hurley, Samuel, Jones, Helen, Lovestone, Simon, Mada, Francisca, Nevado-Holgado, Alejo, Oladejo, Akintayo, Ribe, Elena, Smith, Katy, Vyas, Anviti, Hughes, Zoe, Balice-Gordon, Rita, Duerr, James, Piro, Justin R., Sporn, Jonathan, Perry, V. Hugh, Cleal, Madeleine, Fryatt, Gemma, Gomez-Nicola, Diego, Mancuso, Renzo, Reynolds, Richard, Harrison, Neil A., Cercignani, Mara, Clarke, Charlotte L., Hoskins, Elizabeth, Kohn, Charmaine, Murray, Rosemary, Wilcock, Lauren, Wlazly, Dominika, Mount, Howard, Leckey, Claire, Nevado-Holgado, Alejo J., Barkhof, Frederik, Bertram, Lars, Blin, Olivier, Bos, Isabelle, Dobricic, Valerija, Engelborghs, Sebastiaan, Frisoni, Giovanni, Frölich, Lutz, Gabel, Silvey, Johannsen, Peter, Kettunen, Petronella, Kłoszewska, Iwona, Legido-Quigley, Cristina, Lleó, Alberto, Martinez-Lage, Pablo, Mecocci, Patrizia, Meersmans, Karen, Molinuevo, José Luis, Peyratout, Gwendoline, Popp, Julius, Richardson, Jill, Sala, Isabel, Scheltens, Philip, Streffer, Johannes, Soininen, Hikka, Tainta-Cuezva, Mikel, Teunissen, Charlotte, Tsolaki, Magda, Vandenberghe, Rik, Visser, Pieter Jelle, Vos, Stephanie, Wahlund, Lars-Olof, Wallin, Anders, Westwood, Sarah, and Zetterberg, Henrik

Published
2019
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46. Addressing the accountability gap: gambling advertising and social media platform responsibilities.

Author

Parker, Christine, Albarrán-Torres, César, Briggs, Casey, Burgess, Jean, Carah, Nicholas, Andrejevic, Mark, Angus, Daniel, and Obeid, Abdul

Subjects
*SOCIAL media, *CULTURE, *COST analysis, *LEGISLATION, *GAMBLING, *ADVERTISING, *GOVERNMENT regulation
Abstract

This commentary reports on gambling advertisements served to Australians on Facebook in 2021-2022 that we discovered through a research project that uses novel data donation infrastructure to improve the observability of platform-based advertising. Preliminary findings show that advertisements for online casinos appear on social media and are served to people tagged as located in Australia despite laws that prohibit both the operation and advertising of these gambling services in Australia, and in apparent contravention of company policies that require gambling advertisers to follow applicable law. We outline the harms of normalizing gambling on digital media and argue that the limited accountability of digital platforms for online advertising can contribute to these harms. We suggest ways in which the law and its enforcement and platform responsibility can be reformed to prevent harmful gambling advertising. [ABSTRACT FROM AUTHOR]

Published
2024
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