270 results on '"Park, Woo-Kyu"'
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2. A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway
3. N-(2,7-dimethyl-2-alkyl-2H-chromen-6-yl)sulfonamide derivatives as selective serotonin 5-HT6 receptor antagonists: Design, synthesis, and biological evaluation
4. Rational design of novel diaryl ether-linked benzimidazole derivatives as potent and selective BACE1 inhibitors
5. Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants
6. Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity
7. Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening
8. Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM)
9. Neuregulin 1 Controls Glutamate Uptake by Up-regulating Excitatory Amino Acid Carrier 1 (EAAC1)
10. Synthesis and biological evaluation of 4-nitroindole derivatives as 5-HT2A receptor antagonists
11. Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression
12. Novel pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT2C receptor ligands for the treatment of obesity
13. Discovery of 4-(phenyl)thio-1H-pyrazole derivatives as agonists of GPR109A, a high affinity niacin receptor
14. Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants
15. Discovery of GSK3β Inhibitors through In Silico Prediction-and-Experiment Cycling Strategy, and Biological Evaluation
16. Inhibition of c-Kit signaling by diosmetin isolated from Chrysanthemum morifolium
17. Synthesis and biological evaluation of (phenylpiperazinyl-propyl)arylsulfonamides as selective 5-HT2A receptor antagonists
18. Sphingosylphosphorylcholine Attenuated β–Amyloid Production by Reducing BACE1 Expression and Catalysis in PC12 Cells
19. Preparation of piperazine derivatives as 5-HT 7 receptor antagonists
20. Novel quinazolinone derivatives as 5-HT 7 receptor ligands
21. Evaluation of anti-depressant effects of phthalazinone-based triple-acting small molecules against 5-HT2A, 5-HT2C, and the serotonin transporter
22. Synthesis and Evaluation of a Series of 3,4,5-Trimethoxycinnamic Acid Derivatives as Potential Antinarcotic Agents
23. Development of a time-resolved fluorometric assay for the high throughput screening of melanin concentrating hormone receptor antagonists
24. Bioisosterism: Interchange of 4-OH to 4-NH2 in vanillin or homovanillin ring of capsaicinoids
25. Screening of Kit Inhibitors: Suppression of Kit Signaling and Melanogenesis by Emodin
26. KKHA-761, a potent D 3 receptor antagonist with high 5-HT 1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia
27. Inhibitory effect of the root ofCoptis japonica on catecholamine biosynthesis in PC12 cells
28. Ginsenoside Rg3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons
29. KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia
30. Modulation of the activity of pro-inflammatory enzymes, COX-2 and iNOS, by chrysin derivatives
31. Pharmacological actions of a novel and selective dopamine D3 receptor antagonist, KCH-1110
32. Pharmacological actions of a novel and selective dopamine D 3 receptor antagonist, KCH-1110
33. Inhibitory effects of MK-801 on contextual sensitization to climbing behavior and on development of tolerance to hypothermia induced by a single high dose of apomorphine
34. Synthesis of (3S,4S)-4-aminopyrrolidine-3-ol derivatives and biological evaluation for their BACE1 inhibitory activities
35. NMDA receptor antagonists inhibit apomorphine-induced climbing behavior not only in intact mice but also in reserpine-treated mice
36. KRICT-9 inhibits neuroinflammation, amyloidogenesis and memory loss in Alzheimer’s disease models
37. Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2 H )-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening
38. Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding Inhibitors
39. Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitors
40. Indatraline inhibits Rho- and calcium-mediated glioblastoma cell motility and angiogenesis
41. Synthesis and Biological Evaluation of Substituted Pyrazole Constrained Piperazine Derivative Library for Dopamine Receptor Antagonist
42. Effect ofPanax ginseng on the development of morphine induced tolerance and dependence (VI). On the oral administration of ginseng ether fraction and saponins
43. 5-HT2C receptor selectivity and structure–activity relationship of N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide analogs
44. ChemInform Abstract: A New Amaryllidaceae Alkaloid from the Bulbs of Lycoris radiata.
45. 1-(Arylsulfonyl)-2,3-dihydro-1 H-quinolin-4-one derivatives as 5-HT 6 serotonin receptor ligands
46. Arylpiperazine-containing pyrimidine 4-carboxamide derivatives targeting serotonin 5-HT2A, 5-HT2C, and the serotonin transporter as a potential antidepressant
47. Synthesis and SAR of (piperazin-1-yl-phenyl)-arylsulfonamides: A novel series of atypical antipsychotic agents
48. Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists
49. Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT 2A, 5-HT 2C, and the serotonin transporter as a potential antidepressant
50. A New Amaryllidaceae Alkaloid from the Bulbs of Lycoris radiata
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