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490 results on '"Park, Mi-Jeong"'

7. Asynchronous interface circuit for nonlinear connectivity in multicore spiking neural networks.

Author

Kim, Sung‐Eun, Oh, Kwang‐Il, Kang, Taewook, Lee, Sukho, Kim, Hyuk, Park, Mi‐Jeong, and Lee, Jae‐Jin

Subjects
ARTIFICIAL neural networks, INTERFACE circuits, ASYNCHRONOUS circuits, ARBITRATION & award
Abstract

To expand the scale of spiking neural networks (SNNs), an interface circuit that supports multiple SNN cores is essential. This circuit should be designed using an asynchronous approach to leverage characteristics of SNNs similar to those of the human brain. However, the absence of a global clock presents timing issues during implementation. Hence, we propose an intermediate latching template to establish asynchronous nonlinear connectivity with multipipeline processing between multiple SNN cores. We design arbitration and distribution blocks in the interface circuit based on the proposed template and fabricate an interface circuit that supports four SNN cores using a full‐custom approach in a 28‐nm CMOS (complementary metal–oxide–semiconductor) FDSOI (fully depleted silicon on insulator) process. The proposed template can enhance throughput in the interface circuit by up to 53% compared with the conventional asynchronous template. The interface circuit transmits spikes while consuming 1.7 and 3.7 pJ of power, supporting 606 and 59 Mevent/s in intrachip and interchip communications, respectively. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Detection of RNA Mycoviruses in Wild Strains of Lentinula edodes in Korea

Author

Kim Eunjin, Park Mi-Jeong, Jang Yeongseon, Ryoo Rhim, and Kang-Hyeon Ka

Subjects
lentinula edodes, multiple infection, mushroom, mycovirus, rt-pcr (reverse transcription-polymerase chain reaction), Biology (General), QH301-705.5
Abstract

In general, mycoviruses remain latent and rarely cause visible symptoms in fungal hosts; however, some viral infections have demonstrated abnormal mycelial growth and fruiting body development in commercial macrofungi, including Lentinula edodes. Compared to other cultivated mushrooms, L. edodes is more vulnerable to viral infections as it is still widely cultivated under near-natural conditions. In this study, we investigated whether Korean wild strains of L. edodes were infected by RNA mycoviruses that have previously been reported in other parts of the world (LeSV, LePV1, LeV-HKB, LeNSRV1, and LeNSRV2). Using specific primer sets that target the RNA-dependent RNA polymerase genes of each of the RNA mycovirus, reverse transcription-polymerase chain reaction (RT-PCR) was used to detect viral infection. Viral infection was detected in about 90% of the 112 wild strains that were collected in Korea between 1983 and 2020. Moreover, multiple infections with RNA mycoviruses were detected in strains that had normal fruiting bodies. This work contributes to our understanding of the distribution of RNA mycoviruses in Korea and the impact of multiple viral infections in a single strain of L. edodes.

Published
2021
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34. SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins

Author

Park, Mi-Jeong, Sheng, Ren, Silkov, Antonina, Jung, Da-Jung, Wang, Zhi-Gang, Xin, Yao, Kim, Hyunjin, Thiagarajan-Rosenkranz, Pallavi, Song, Seohyeon, Yoon, Youngdae, Nam, Wonhee, Kim, Ilshin, Kim, Eui, Lee, Dong-Gyu, Chen, Yong, Singaram, Indira, Wang, Li, Jang, Myoung Ho, Hwang, Cheol-Sang, Honig, Barry, Ryu, Sungho, Lorieau, Justin, Kim, You-Me, and Cho, Wonhwa

Published
2016
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36. Cloning and Expression Analysis of Bioluminescence Genes in Omphalotus guepiniiformisReveal Stress-Dependent Regulation of Bioluminescence

Author

Park, Mi-Jeong, Kim, Eunjin, Kim, Min-Jun, Jang, Yeongseon, Ryoo, Rhim, and Ka, Kang-Hyeon

Abstract

AbstractBioluminescence is a type of chemiluminescence that arises from a luciferase-catalyzed oxidation reaction of luciferin. Molecular biology and comparative genomics have recently elucidated the genes involved in fungal bioluminescence and the evolutionary history of their clusters. However, most studies on fungal bioluminescence have been limited to observing the changes in light intensity under various conditions. To understand the molecular basis of bioluminescent responses in Omphalotus guepiniiformisunder different environmental conditions, we cloned and sequenced the genes of hispidin synthase, hispidin-3-hydroxylase, and luciferase enzymes, which are pivotal in the fungal bioluminescence pathway. Each gene showed high sequence similarity to that of other luminous fungal species. Furthermore, we investigated their transcriptional changes in response to abiotic stresses. Wound stress enhanced the bioluminescence intensity by increasing the expression of bioluminescence pathway genes, while temperature stress suppressed the bioluminescence intensity viathe non-transcriptional pathway. Our data suggested that O. guepiniiformisregulates bioluminescence to respond differentially to specific environmental stresses. To our knowledge, this is the first study on fungal bioluminescence at the gene expression level. Further studies are required to address the biological and ecological meaning of different bioluminescence responses in changing environments, and O. quepiniiformiscould be a potential model species.

Published
2024
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43. Targeting lipid–protein interaction to treat Syk-mediated acute myeloid leukemia

Author

Singaram, Indira, primary, Sharma, Ashutosh, additional, Pant, Shashank, additional, Lihan, Muyun, additional, Park, Mi-Jeong, additional, Pergande, Melissa, additional, Buwaneka, Pawanthi, additional, Hu, Yusi, additional, Mahmud, Nadim, additional, Kim, You-Me, additional, Cologna, Stephanie, additional, Gevorgyan, Vladimir, additional, Khan, Irum, additional, Tajkhorshid, Emad, additional, and Cho, Wonhwa, additional

Published
2022
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