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6. Clostridium difficile Strains from Community-Associated Infections

Author

Limbago, Brandi M., primary, Long, Cherie M., additional, Thompson, Angela D., additional, Killgore, George E., additional, Hannett, George E., additional, Havill, Nancy L., additional, Mickelson, Stephanie, additional, Lathrop, Sarah, additional, Jones, Timothy F., additional, Park, Mahin M., additional, Harriman, Kathleen H., additional, Gould, L. Hannah, additional, McDonald, L. Clifford, additional, and Angulo, Frederick J., additional

Published
2009
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7. West Nile Virus among Hospitalized, Febrile Patients: A Case for Expanding Diagnostic Testing

Author

Whitney, Ellen A. Spotts, primary, Heilpern, Katherine L., additional, Woods, Christopher W., additional, Bahn, C. Christina, additional, Franko, Elizabeth A., additional, Silk, Benjamin J., additional, Ratcliff, Jonathan J., additional, Bryant, Katherine A., additional, Park, Mahin M., additional, Watkins, Sandra J., additional, Caram, Lauren B., additional, Blumberg, Henry M., additional, and Berkelman, Ruth L., additional

Published
2006
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10. Clostridium difficileStrains from Community-Associated Infections

Author

Limbago, Brandi M., Long, Cherie M., Thompson, Angela D., Killgore, George E., Hannett, George E., Havill, Nancy L., Mickelson, Stephanie, Lathrop, Sarah, Jones, Timothy F., Park, Mahin M., Harriman, Kathleen H., Gould, L. Hannah, McDonald, L. Clifford, and Angulo, Frederick J.

Abstract

ABSTRACTClostridium difficileisolates from presumed community-associated infections (n= 92) were characterized by toxinotyping, pulsed-field gel electrophoresis, tcdCand cdtBPCR, and antimicrobial susceptibility. Nine toxinotypes (TOX) and 31 PFGE patterns were identified. TOX 0 (48, 52%), TOX III (18, 20%), and TOX V (9, 10%) were the most common; three isolates were nontoxigenic.

Published
2009
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13. West Nile virus among hospitalized, febrile patients: a case for expanding diagnostic testing.

Author

Whitney EA, Heilpern KL, Woods CW, Bahn CC, Franko EA, Del Rio C, Silk BJ, Ratcliff JJ, Bryant KA, Park MM, Watkins SJ, Caram LB, Blumberg HM, and Berkelman RL

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Diagnostic Tests, Routine standards, Female, Fever virology, Georgia epidemiology, Hospitalization, Humans, Immunoglobulin G blood, Immunoglobulin M blood, Male, Middle Aged, Population Surveillance methods, Time Factors, West Nile Fever immunology, West Nile Fever virology, West Nile virus immunology, West Nile Fever diagnosis, West Nile Fever epidemiology, West Nile virus isolation & purification
Abstract

In Georgia, most individuals reported with West Nile virus (WNV) disease have been diagnosed with West Nile neuroinvasive disease (WNND). Relatively few cases of West Nile Fever (WNF) are reported, and the burden of illness due to WNV is likely underestimated. From July through October 2003, WNV serologic testing was performed on enrolled patients>or=18 years of age with fever admitted to a large, urban hospital in Atlanta, Georgia through the emergency department (ED). Patients' history, clinical, and laboratory data were recorded. Residual blood drawn in the ED was tested to determine the presence of WNV IgG and IgM antibodies. Of 254 patients tested for WNV, four (1.6%) patients were positive for WNV IgM and IgG antibodies, and had a clinical illness compatible with WNV. None of the four positive patients were clinically suspected of having WNV infection; discharge diagnoses included pneumonia, migraine, stroke, and gout. These four patients accounted for 80% of all WNV diagnosed in this hospital, 44% of all cases in Fulton County, and 7% of all cases reported in Georgia in 2003. The occurrence of WNV disease may be substantially greater than currently reflected in disease statistics in Georgia and many other states. When indicators of WNV activity are present and patients are likely to have had intensive mosquito exposure, WNV should be considered in the differential diagnosis of seriously ill, febrile patients.

Published
2006
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