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871 results on '"Park, Jae-Hyeong"'

2. 2023 Korean Society of Echocardiography position paper for diagnosis and management of valvular heart disease, part I: aortic valve disease

Author

Lee, Sun Hwa, Yoon, Se-Jung, Sun, Byung Joo, Kim, Hyue Mee, Kim, Hyung Yoon, Lee, Sahmin, Shim, Chi Young, Kim, Eun Kyoung, Cho, Dong-Hyuk, Park, Jun-Bean, Seo, Jeong-Sook, Son, Jung-Woo, Kim, In-Cheol, Lee, Sang-Hyun, Heo, Ran, Lee, Hyun-Jung, Park, Jae-Hyeong, Song, Jong-Min, Lee, Sang-Chol, Kim, Hyungseop, Kang, Duk-Hyun, Ha, Jong-Won, and Kim, Kye Hun

Published
2024
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3. 2023 Korean Society of Echocardiography position paper for the diagnosis and management of valvular heart disease, part II: mitral and tricuspid valve disease

Author

Shim, Chi Young, Kim, Eun Kyoung, Cho, Dong-Hyuk, Park, Jun-Bean, Seo, Jeong-Sook, Son, Jung-Woo, Kim, In-Cheol, Lee, Sang-Hyun, Heo, Ran, Lee, Hyun-Jung, Lee, Sahmin, Sun, Byung Joo, Yoon, Se-Jung, Lee, Sun Hwa, Kim, Hyung Yoon, Kim, Hyue Mee, Park, Jae-Hyeong, Hong, Geu-Ru, Jung, Hae Ok, Kim, Yong-Jin, Kim, Kye Hun, Kang, Duk-Hyun, Ha, Jong-Won, and Kim, Hyungseop

Published
2024
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16. Intravascular ultrasound-guided drug-coated balloon angioplasty for femoropopliteal artery disease: a clinical trial.

Author

Ko, Young-Guk, Lee, Seung-Jun, Ahn, Chul-Min, Lee, Sang-Hyup, Lee, Yong-Joon, Kim, Byeong-Keuk, Hong, Myeong-Ki, Jang, Yangsoo, Kim, Tae-Hoon, Park, Ha-Wook, Jang, Ji Yong, Lee, Jae-Hwan, Park, Jae-Hyeong, Kim, Su Hong, Im, Eui, Park, Sang-ho, Choi, Donghoon, and investigators, IVUS-DCB

Subjects
INTRAVASCULAR ultrasonography, TRANSLUMINAL angioplasty, ENDOVASCULAR surgery, PERIPHERAL vascular diseases, ARTERIAL diseases
Abstract

Background and Aims Drug-coated balloons (DCBs) have demonstrated favourable outcomes following endovascular therapy for femoropopliteal artery (FPA) disease. However, uncertainty remains whether the use of intravascular ultrasound (IVUS) can improve the outcomes of DCBs. Methods This prospective, multicentre, randomized trial, conducted at seven centres in South Korea, compared the outcomes of IVUS-guided vs. angiography-guided angioplasty for treating FPA disease with DCBs. Patients were assigned to receive IVUS-guided (n = 119) or angiography-guided (n = 118) angioplasty using DCBs. The primary endpoint was 12-month primary patency. Results Between May 2016 and August 2022, 237 patients were enrolled and 204 (86.0%) completed the trial (median follow-up; 363 days). The IVUS guidance group showed significantly higher primary patency [83.8% vs. 70.1%; cumulative difference 19.6% (95% confidence interval 6.8 to 32.3); P =.01] and increased freedom from clinically driven target lesion revascularization [92.4% vs. 83.0%; difference 11.6% (95% confidence interval 3.1 to 20.1); P =.02], sustained clinical improvement (89.1% vs. 76.3%, P =.01), and haemodynamic improvement (82.4% vs. 66.9%, P =.01) at 12 months compared with the angiography guidance group. The IVUS group utilized larger balloon diameters and pressures for pre-dilation, more frequent post-dilation, and higher pressures for post-dilation, resulting in a greater post-procedural minimum lumen diameter (3.90 ± 0.59 vs. 3.71 ± 0.73 mm, P =.03). Conclusions Intravascular ultrasound guidance significantly improved the outcomes of DCBs for FPA disease in terms of primary patency, freedom from clinically driven target lesion revascularization, and sustained clinical and haemodynamic improvement at 12 months. These benefits may be attributed to IVUS-guided optimization of the lesion before and after DCB treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Efficacy and safety of combination therapy with telmisartan, rosuvastatin, and ezetimibe in patients with dyslipidemia and hypertension: A randomized, double‐blind, multicenter, therapeutic confirmatory, phase III clinical trial

Author

Lee, Chan Joo, primary, Kang, Woong Chol, additional, Ihm, Sang Hyun, additional, Sohn, Il Suk, additional, Woo, Jong Shin, additional, Kim, Jin Won, additional, Hong, Soon Jun, additional, Choi, Jung Hyun, additional, Suh, Jung‐Won, additional, Seo, Jae‐Bin, additional, Doh, Joon‐Hyung, additional, Son, Jung‐Woo, additional, Park, Jae‐Hyeong, additional, Lee, Ju‐Hee, additional, Hong, Young Joon, additional, Heo, Jung Ho, additional, Shin, Jinho, additional, and Kang, Seok‐Min, additional

Published
2024
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20. Safety, Virologic Efficacy, and Pharmacokinetics of CT-P59, a Neutralizing Monoclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Protein: Two Randomized, Placebo-Controlled, Phase I Studies in Healthy Individuals and Patients With Mild SARS-CoV-2 Infection

Author

Kim, Jin Yong, Jang, Young Rock, Hong, Jang Hee, Jung, Jin Gyu, Park, Jae-Hyeong, Streinu-Cercel, Adrian, Streinu-Cercel, Anca, Săndulescu, Oana, Lee, Sang Joon, Kim, Sung Hyun, Jung, Na Hyun, Lee, Seul Gi, Park, Jeong Eun, Kim, Min Kyung, Jeon, Da Bee, Lee, Yeo Jin, Kim, Bum Soo, Lee, Yeon Mi, and Kim, Yeon-Sook

Published
2021
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26. Association Between Orthostatic Hypertension and Frailty Among Older Patients With Hypertension.

Author

Choi, Jung-Yeon, Ryu, Dong Ryeol, Lee, Hae-Young, Lee, Ju-Hee, Hong, Youjin, Park, Sue K., Lee, Jang Hoon, Hwang, Seok-Jae, Kim, Kye Hun, Lee, Sun Hwa, Kim, Song Yi, Park, Jae-Hyeong, Kim, Sang-Hyun, Kim, Hack-Lyoung, Choi, Jung Hyun, Kim, Cheol-Ho, Cho, Myeong-Chan, and Kim, Kwang-il

Abstract

BACKGROUND: Frailty frequently coexists with hypertension in older patients. We aimed to evaluate the association between frailty and positional change in blood pressure, especially orthostatic hypertension. METHODS: Participants were recruited from 12 University hospitals in South Korea. Using a digital device, trained research nurses measured blood pressure in the supine and standing positions. Physical frailty was evaluated using the Korean version of the FRAIL questionnaire, gait speed, and handgrip strength. Orthostatic hypertension was defined as a ≥20-mm Hg increase in systolic blood pressure within 3 minutes of standing and upright systolic blood pressure of ≥140 mm Hg. RESULTS: We analyzed the data of 2065 participants who had been enrolled until December 31, 2022. The mean age was 73.2±5.6 years, and 52.0% were female. The mean blood pressure was 137.1±14.9/75.1±9.7 mm Hg. Among the participants, 1886 (91.3%) showed normal response after standing, but 94 (4.6%) had orthostatic hypertension, and 85 (4.1%) had orthostatic hypotension. Orthostatic hypertension was associated with female sex, obesity, cognitive function, physical frailty, and lower quality of life. In the multivariable analysis, body mass index and frailty status were independently associated with orthostatic hypertension. CONCLUSIONS: Orthostatic hypertension is associated with physical frailty, cognitive impairment, and low quality of life in older patients with hypertension. Therefore, evaluation of orthostatic blood pressure changes to confirm orthostatic hypertension or hypotension in frail older adults will serve as an important diagnostic procedure in vulnerable patients. Further studies are required to identify the underlying mechanisms of this association. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Effect of Ticagrelor on Left Ventricular Remodeling in Patients With ST-Segment Elevation Myocardial Infarction (HEALING-AMI)

Author

Park, Yongwhi, Kwak, Choong Hwan, Jeong, Young-Hoon, Koh, Jin-Sin, Hwang, Seok-Jae, Hwang, Jin-Yong, Park, Hyun-Woong, Kang, Min Gyu, Park, Jeong Rang, Kim, Kyehwan, Kim, Jin Hyun, Park, Jae-Hyeong, Seong, In-Whan, Choi, Si-Wan, Lee, Jae-Hwan, Shin, Eun Seok, Ann, Soe Hee, Kim, Shin Jae, Oh, Ju Hyeon, Chun, Woojung, Kang, Gu Hyun, Lee, Mi Rae, Jang, Woo Jin, Park, Yong Hwan, Lee, Sang Yeub, Bae, Jang-Whan, Kim, Sang Min, Lee, Chung Suk, Kim, Jeongsu, Kim, June Hong, Chun, Kook Jin, Chon, Min Gu, Lee, Sang Hyun, Kim, Weon, Kim, Woo-Shik, Kim, Jin-Bae, Woo, Jong-Shin, Suh, Jung-Won, Chae, In-Ho, Youn, Tae-Jin, Cho, Young Seok, Yoon, Chang-Hwan, Park, Jin Joo, Kang, Si-Hyuck, Lee, Euijae, Kim, Donghoon, Kang, Jeehoon, Yang, Dong Heon, Ki, Nam Kyun, Lee, Jang Hoon, Hong, Young Joon, Cho, Jaeyeong, Kim, Min Chul, Sim, Doo Sun, Chan, Mark Y., Marchesseau, Stephanie, Koh, Jin Sin, Shin, Eun-Seok, Kim, Jeong Su, Hong, Young-Joon, Ahn, Jong-Hwa, and Choi, Si Wan

Published
2020
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35. Increased Blood Pressure Variability Over a 16-Year Period Is Associated With Left Ventricular Diastolic Dysfunction in a Population-Based Cohort.

Author

Park, Jae-Hyeong, Ahn, Soon-Ki, Cho, Goo-Yeong, Sung, Ki-Chul, Lee, Seung Ku, Kim, Seong Hwan, and Shin, Chol

Subjects
LEFT ventricular dysfunction, BLOOD pressure, BODY mass index, HYPERTENSION
Abstract

BACKGROUND Left ventricular diastolic dysfunction (LVDD) is often associated with elevated blood pressure (BP). It is prevalent among hypertensive patients. Additionally, increased BP variability has been linked to LVDD. However, the precise connection between LVDD and BP variability within the general population remains unclear. Thus, this study aimed to evaluate this association in a general population. METHODS A total of 2,578 participants(1,311 females) with a mean age of 47.8 ± 6.7 years who had echocardiographic data from the Korean Genome and Epidemiology study with 16 years of follow-up were analyzed. LVDD was identified through the last echocardiography during the follow-up period. BP variability was assessed using mean, standard deviation (SD), and coefficient of variance (CV). RESULTS LVDD was detected in 249 individuals. The cohort was divided into an LVDD group and a normal LV diastolic function group. The LVDD group had a higher percentage of females, more advanced age, higher body mass index (BMI), higher BP and BUN levels, lower heart rate, lower hemoglobin, and lower serum creatinine than the normal LV diastolic function group. Remarkably, LVDD was associated with higher BP variability. In the multivariate analysis, LVDD was associated with increased age, female sex, increased BMI, hypertension, and increased BUN. Elevated mean systolic and diastolic BPs, SD of systolic BP, mean pulse pressure (PP), SD of PP, and CV of PP were significantly linked to LVDD even after adjusting for other significant variables in the multivariate analysis. CONCLUSIONS LVDD was identified in 249 (9.7%) participants. Increased long-term BP variability was significantly associated with LVDD in this population-based cohort. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Efficacy and Safety of Ezetimibe and Rosuvastatin Combination Therapy Versus Those of Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia

Author

Kim, Woohyeun, Yoon, Yeonyee E., Shin, Sung-Hee, Bae, Jang-Whan, Hong, Bum-Kee, Hong, Soon Jun, Sung, Ki Chul, Han, Seung Hwan, Kim, Weon, Rhee, Moo-Yong, Kim, Sang-Hyun, Lee, Sang Eun, Hyon, Min Su, Hwang, Gyo-Seung, Son, Jang Won, Kim, Jang-Young, Kim, Min Kyu, Kim, Sang Wook, Park, Jae-Hyeong, Shin, Jin Ho, and Park, Chang Gyu

Published
2018
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43. COVID-19 vaccination-related myocarditis: a Korean nationwide study

Author

Cho, Jae Yeong, primary, Kim, Kye Hun, additional, Lee, Nuri, additional, Cho, Soo Hyeon, additional, Kim, Seung Yun, additional, Kim, Eun Kyoung, additional, Park, Jae-Hyeong, additional, Choi, Eui-Young, additional, Choi, Jin-Oh, additional, Park, Hyukjin, additional, Kim, Hyung Yoon, additional, Yoon, Hyun Ju, additional, Ahn, Youngkeun, additional, Jeong, Myung Ho, additional, and Cho, Jeong Gwan, additional

Published
2023
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