Search

Your search keyword '"Park, Heung-Kyu"' showing total 146 results
Start Over Author "Park, Heung-Kyu"
146 results on '"Park, Heung-Kyu"'

5. Poor Prognosis of Lower Inner Quadrant in Lymph Node–negative Breast Cancer Patients Who Received No Chemotherapy: A Study Based on Nationwide Korean Breast Cancer Registry Database

Author

Ahn, Sei Hyun, Noh, Dong-Young, Nam, Seok Jin, Lee, Eun Sook, Park, Byeong-Woo, Noh, Woo Chul, Yoon, Jung Han, Lee, Soo Jung, Lee, Eun Kyu, Jeong, Joon, Han, Sehwan, Park, Ho Yong, Paik, Nam-Sun, Bae, Young Tae, Lee, Hyouk Jin, Park, Heung Kyu, Ko, Seung Sang, Song, Byung Joo, Suh, Young Jin, Jung, Sung Hoo, Cho, Se Heon, Kim, Sei Joong, Oh, Se Jeong, Ko, Byung Kyun, Kim, Ku Sang, Park, Chanheun, Baek, Jong-Min, Hwang, Ki-Tae, Chang, Il-Sung, Bae, Jeoung Won, Kim, Jeong-Soo, Kang, Sun Hee, Gwak, Geumhee, Lee, Jee Hyun, Kim, Tae Hyun, Chang, Myungchul, Kim, Sung Yong, Lee, Jung Sun, Song, Jeong-Yoon, Park, Hai Lin, Min, Sun Young, Yang, Jung-Hyun, Park, Sung Hwan, Park, Woo-Chan, Kim, Lee Su, Ryu, Dong Won, Kim, Kweon Cheon, Chung, Min Sung, Park, Hee Boong, Lim, Cheol Wan, Choi, Un Jong, Kwak, Beom Seok, Park, Young Sam, Shin, Hyuk Jai, Choi, Young Jin, Kim, Doyil, Han, Airi, Koh, Jong Hyun, Choi, Sangyong, Yoon, Daesung, Choi, Soo Youn, Chul, Shin Hee, Kim, Jae Il, Choi, Jae Hyuck, Ryu, Jin Woo, Ko, Chang Dae, Lee, Il Kyun, Lee, Dong Seok, Choi, Seunghye, Min, Youn Ki, Jeon, Young San, Park, Eun-Hwa, Kim, Jongjin, Kim, Eun-Kyu, Sohn, Guiyun, Kim, Seung Il, Park, Jin Hyun, and Oh, Sohee

Published
2017
Full Text
View/download PDF

9. Exploration of Point-of-Care Ultrasonography for Silicone Breast Implant Rupture Detection and Classification.

Author

Kim, Jae-Hong, Kim, Yun-Gyoung, Song, Keun-Yeong, Lim, Hyung-Guhn, Jeong, Jeong-Pil, Sung, Jung-Youp, Lee, Angela-Soeun, and Park, Heung-Kyu

Subjects
BREAST implants, BREAST ultrasound, POINT-of-care testing, ULTRASONIC imaging, EARLY diagnosis, CLASSIFICATION
Abstract

Background and Objectives: The surge in breast-related surgeries in Korea underscores the critical need for an accurate early diagnosis of silicone breast implant-related issues. Complications such as BIA-ALCL and BIA-SCC add complexity to breast health concerns, necessitating vigilant monitoring. Despite advancements, discrepancies persist between ultrasonographic and pathologic classifications of silicone implant ruptures, highlighting a need for enhanced diagnostic tools. This study explores the reliability of ultrasonography in diagnosing silicone breast implant ruptures and determining the extent of silicone migration, specifically with a focus on guiding potential capsulectomy based on pathology. Materials and Methods: A comprehensive review of medical records encompassing 5557 breast implants across 2790 patients who underwent ultrasound-assisted examinations was conducted. Among the screened implants, 8.9% (249 cases) were diagnosed with silicone breast implant rupture through ultrasonography. Subsequently, 89 women underwent revisional surgery, involving capsulectomy. The pathological analysis of 111 periprosthetic capsules from these cases aimed to assess the extent of silicone migration, and the findings were juxtaposed with the existing ultrasonographic rupture classification. Results: The diagnostic agreement between preoperative sonography and postoperative findings reached 100% for silicone breast implant ruptures. All eighty prosthetic capsules exhibiting a snowstorm sign in ultrasonography demonstrated silicone migration to capsules upon pathologic findings. Conclusions: High-resolution ultrasonography emerged as a valuable and reliable imaging modality for diagnosing silicone breast implant ruptures, with a notable ability to ascertain the extent of free silicone migration to capsules. This diagnostic precision is pivotal in informing decisions about potential capsulectomy during revisional surgery. The study advocates for an update to the current binary ultrasonographic classification, suggesting a more nuanced categorization into three types (subcapsular, intracapsular, and extracapsular) based on pathology. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

15. Additional file 1 of Clinical significance of HER2-low expression in early breast cancer: a nationwide study from the Korean Breast Cancer Society

Author

Won, Hye Sung, Ahn, Juneyoung, Kim, Yongseon, Kim, Jin Sung, Song, Jeong-Yoon, Kim, Hong-Kyu, Lee, Jeeyeon, Park, Heung Kyu, and Kim, Yong-Seok

Subjects
skin and connective tissue diseases
Abstract

Additional file 1: Table S1. Adjuvant treatments according to HER2 status within hormone receptor-positive and triple-negative breast cancer.

Published
2022
Full Text
View/download PDF

16. Additional file 4 of Clinical significance of HER2-low expression in early breast cancer: a nationwide study from the Korean Breast Cancer Society

Author

Won, Hye Sung, Ahn, Juneyoung, Kim, Yongseon, Kim, Jin Sung, Song, Jeong-Yoon, Kim, Hong-Kyu, Lee, Jeeyeon, Park, Heung Kyu, and Kim, Yong-Seok

Subjects
skin and connective tissue diseases
Abstract

Additional file 4: Figure S2. Forest plot with hazard ratio showing BCSS according to HER2 IHC score in hormone receptor-positive breast cancer (A) and in triple-negative breast cancer (B).

Published
2022
Full Text
View/download PDF

23. Clinical implication of subcategorizing T2 category into T2a and T2b in TNM staging of breast cancer

Author

Jung, Jiwoong, Suh, Young Jin, Ko, Byung Kyun, Lee, Eun Sook, Kim, Eun‐Kyu, Paik, Nam Sun, Byun, Kyung Do, Hwang, Ki‐Tae, Ahn, Sei Hyun, Noh, Dong‐Young, Nam, Seok Jin, Park, Byeong‐Woo, Noh, Woo Chul, Yoon, Jung Han, Lee, Soo Jung, Lee, Eun Kyu, Jeong, Joon, Han, Sehwan, Park, Ho Yong, Paik, Nam‐Sun, Bae, Young Tae, Lee, Hyouk Jin, Park, Heung kyu, Ko, Seung Sang, Park, Woo‐Chan, Jung, Sung Hoo, Cho, Se Heon, Kim, Sei Joong, Oh, Se Jeong, Kim, Ku Sang, Park, Chanheun, Song, Byung Joo, Kim, Je Ryong, Bae, Jeoung Won, Kim, Jeong‐Soo, Kang, Sun Hee, Gwak, Geumhee, Lee, Jee Hyun, Kim, Tae Hyun, Chang, Myungchul, Kim, Sung Yong, Lee, Jung Sun, Song, Jeong‐Yoon, Park, Hai Lin, Min, Sun Young, Yang, Jung‐Hyun, Park, Sung Hwan, Baek, Jong‐Min, Kim, Lee Su, Ryu, Dong Won, Kim, Kweon Cheon, Chung, Min Sung, Park, Hee Boong, Lim, Cheol Wan, Choi, Un Jong, Kwak, Beom Seok, Park, Young Sam, Shin, Hyuk Jai, Choi, Young Jin, Kim, Doyil, Han, Airi, Koh, Jong Hyun, Choi, Sangyong, Yoon, Daesung, Choi, Soo Youn, Chul, Shin Hee, Kim, Jae Il, Choi, Jae Hyuck, Ryu, Jin Woo, Ko, Chang Dae, Lee, Il Kyun, Lee, Dong Seok, Choi, Seunghye, Min, Youn Ki, Jeon, Young San, and Park, Eun‐Hwa

Subjects
Oncology, Cancer Research, medicine.medical_specialty, Multivariate analysis, TNM staging, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, Adjuvant therapy, breast neoplasms, Cutoff, Medicine, Humans, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, Original Research, Neoplasm Staging, Subcategory, Receiver operating characteristic, business.industry, Hazard ratio, Clinical Cancer Research, tumor staging, Middle Aged, medicine.disease, Tumor Burden, 030220 oncology & carcinogenesis, TNM Staging, Female, prognosis, business
Abstract

Regarding TNM staging in breast cancer, T2 category is currently not divided into subcategories even though it covers a wider range of tumor sizes than T1 category. Using Korean Breast Cancer Registry database, data of 41 071 women diagnosed as non‐metastatic T2 breast cancer between 2001 and 2014 were analyzed. Cutoff value for optimal tumor size was approximated by receiver operating characteristic (ROC) curve to subcategorize T2 tumors. Overall survival (OS) was compared between two subcategories. Median follow‐up period was 65 months. Of 41 071 patients, 4504 (11.0%) died. Based on ROC curve analysis, 3.0 cm was selected as the cutoff value. Five‐year OS rate was 91% in patients with breast tumors ≤3.0 cm (T2a) and 86% in patients with breast tumors >3.0 cm (T2b) (log‐rank P

Published
2018

24. A critical review of abdominopelvic computed tomography for the detection of asymptomatic metastasis in new and recurrent breast cancers.

Author

Nam, Sang Yu, Ahn, Su Joa, Jang, Young Rock, Chun, Yong Soon, Park, Heung Kyu, Choi, Seung Joon, Choi, Hye Young, and Kim, Jeong Ho

Subjects
METASTATIC breast cancer, COMPUTED tomography, BREAST cancer, EPIDERMAL growth factor, CANCER invasiveness
Abstract

Aim: Abdominopelvic computed tomography (APCT) is a commonly used staging investigation to detect asymptomatic metastasis in breast cancer including early breast cancer (EBC). This study aimed to assess the usefulness of APCT in breast cancers at each clinical stage. Methods: Patients with new or recurrent invasive breast cancer between January 2009 and December 2014 were included in the study. All staging APCT results were reviewed to evaluate its yield and false positive rate (FPR) and how many investigations are needed to confirm indeterminate results. Odds ratios (ORs) for positive APCT results were calculated for possible risk factors for asymptomatic metastasis. Results: Sixty‐five asymptomatic metastases were detected from 1002 APCTs, giving an overall yield of 6.5%. The overall false‐positive rate was 14.9 % due to 149 indeterminate findings that were found not to be metastases after further investigations or observation. Whereas the APCTs have a low yield of 3.1% in EBC, but advanced breast cancer and recurrent breast cancer have a high incidence of asymptomatic metastases (13.8% and 16.3%, respectively). The most common cause of indeterminate findings was small liver nodules, including liver cysts and liver hemangiomas. Human epidermal growth factor receptor2 (HER2) status and tumor stage are most significant predictors for positive results of staging APCT scans with high ORs (3.9 and 3.7, respectively). Conclusion: Staging APCT is associated with a high incidence of FPRs and low yield, especially among EBCs. It is desirable to choose this investigation more selectively according to HER2 status and tumor stage. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

26. Clinical Outcomes Following Letrozole Treatment according to Estrogen Receptor Expression in Postmenopausal Women: LETTER Study (KBCSG-006)

Author

Ahn, Sung Gwe, primary, Nam, Seok Jin, additional, Ahn, Sei Hyun, additional, Jung, Yongsik, additional, Park, Heung Kyu, additional, Lee, Soo Jung, additional, Kang, Sung Soo, additional, Han, Wonshik, additional, Park, Kyong Hwa, additional, Park, Yong Lai, additional, Lee, Jihyoun, additional, Youn, Hyun Jo, additional, Kim, Jun Hyun, additional, Yoo, Youngbum, additional, Song, Jeong-Yoon, additional, Ko, Byung Kyun, additional, Gwak, Geumhee, additional, Chung, Min Sung, additional, Kim, Sung Yong, additional, Cho, Seo Heon, additional, Kim, Doyil, additional, Chang, Myung-Chul, additional, Moon, Byung In, additional, Kim, Lee Su, additional, Kim, Sei Joong, additional, Park, Min Ho, additional, Kim, Tae Hyun, additional, Cho, Jihyoung, additional, Lim, Cheol Wan, additional, Bae, Young Tae, additional, Gong, Gyungyub, additional, Bae, Young Kyung, additional, Lee, Ahwon, additional, and Jeong, Joon, additional

Published
2021
Full Text
View/download PDF

32. The efficacy of oxidized regenerated cellulose (SurgiGuard®) in breast cancer patients who undergo total mastectomy with node surgery: A prospective randomized study in 94 patients.

Author

Nam, Kug Hyun, Lee, Joon-Hyop, Chung, Yoo Seung, Chun, Yong Soon, Park, Heung Kyu, and Kim, Yun Yeong

Subjects
AXILLARY lymph node dissection, SENTINEL lymph node biopsy, CANCER patients, MASTECTOMY, BREAST cancer, BREAST implants, ATRIOVENTRICULAR node, BREAST, CEREBROSPINAL fluid shunts
Abstract

Background: Seromas frequently develop in patients who undergo total mastectomy with node surgery. We aimed to prospectively explore whether use of oxidized regenerated cellulose (ORC, SurgiGuard®) affects seroma formation after total mastectomy with node surgery (sentinel lymph node biopsy (SLNB) or axillary lymph node dissection (ALND)). Materials and methods: Ninety four breast cancer patients were enrolled in the study who underwent total mastectomy with ALND or SLNB. The patients were randomized into two groups, one treated with ORC plus closed suction drainage and the other with closed suction drainage alone. Results: Mean drainage volume was slightly lower in the ORC group on postoperative day 1 (123 ± 54 vs 143 ± 104 ml), but was slightly higher at all other time points; however, these differences were not significant. Mean total drainage volume in patients treated with ORC plus drainage did not differ from that of patients treated with drainage alone (1134 ± 507 ml vs 1033 ± 643 ml, P = 0.486). Conclusions: Use of ORC (SurgiGuard®) did not significantly alter the risk of seroma formation. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

40. Response to neoadjuvant chemotherapy based on pathologic complete response in very young patients with ER-positive breast cancer: a large, multicenter, observational study.

Author

Joohyun Woo, Se Jeong Oh, Jeong-Yoon Song, Byung Joo Chae, Jung Eun Choi, Jeeyeon Lee, Heung Kyu Park, Woosung Lim, Woo, Joohyun, Oh, Se Jeong, Song, Jeong-Yoon, Chae, Byung Joo, Choi, Jung Eun, Lee, Jeeyeon, Park, Heung Kyu, Korean Breast Cancer Society, and Lim, Woosung

Abstract

Background: In estrogen receptor (ER)-positive breast cancer (BC), young age is associated with poor prognosis. While very young patients respond better to chemotherapy, chemotherapy is less effective in ER-positive tumors than in ER-negative tumors. The authors tried to evaluate chemotherapy response of very young patients with ER-positive BC by pathologic complete response (pCR) after neoadjuvant chemotherapy excluding the effect of endocrine treatment to the extent possible.Methods: We collected individual patient data from 1992 to 2013 from the Korean Breast Cancer Society (KBCS). Total 1048 ER-positive and 797 ER-negative patients aged < 50 years who had been treated with neoadjuvant chemotherapy were included for analysis. We compared pCR rate between patients aged < 35 years with ER-positive tumors and the other groups.Results: The proportion of patients aged < 35 years was 14.0% of patients with ER-positive BC in this cohort of under 50 years old, and 16.8% of patients with ER-negative BC in this cohort of under 50 years old. Although most characteristics of tumors according to age were comparable, tumors with high Ki-67 expression were more common in patients aged < 35 years than in patients aged 35-49 years in both ER-positive and -negative group (P = 0.001). Breast conservation rates were not significantly different according to age (44.2% vs. 46.8% in ER-positive group, 55.2% vs. 48.0% in ER-negative group). pCR rate was not different according to age in ER-positive group (P = 0.71) but significantly better in patients aged < 35 years in ER-negative group (P = 0.009). After adjusting for confounding variables, young patients maintained the higher probability of pCR than older patients in ER-negative tumors. However, pCR rate did not differ according to age in ER-positive tumors. In multivariate analysis, young age (< 35 years) was correlated with poor overall survival (P = 0.003, HR = 1.98) and there was only one event in a few patients achieved pCR in ER-positive group.Conclusions: Chemotherapy response based on pCR was not better in young patients (< 35 years) with ER-positive BC than in older premenopausal patients with non-metastatic ER-positive BC. Young age cannot be a predictive factor of response to neoadjuvant chemotherapy in ER-positive BC. Different biological characteristics such as high proliferative index should be considered.Trial Registration: Retrospectively registered. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

46. Assessment of Quality of Life and Safety in Postmenopausal Breast Cancer Patients Receiving Letrozole as an Early Adjuvant Treatment

Author

Jung, Yongsik, primary, Lee, Soo Jung, additional, Lee, Juneyoung, additional, Noh, Woo Chul, additional, Nam, Seok Jin, additional, Park, Byeong-Woo, additional, Bae, Young Tae, additional, Kang, Sung-Soo, additional, Park, Heung Kyu, additional, Yoon, Jung-Han, additional, Kim, Je Ryong, additional, Cho, Se Hun, additional, Kim, Lee Su, additional, Moon, Byung In, additional, Jung, Sung Hoo, additional, Lim, Chol Wan, additional, Kim, Sung Yong, additional, Park, Ho Yong, additional, Song, Jeongyoon, additional, Lee, Kwang Man, additional, Park, Sung Hwan, additional, Jeong, Joon, additional, Park, Hae Lin, additional, Kim, Sung Won, additional, Kwak, Beom Seok, additional, Kang, Sun Hee, additional, Cho, Young Up, additional, Gwak, Geum Hee, additional, Park, Yong Lae, additional, Kim, Sang Wook, additional, and Han, Sehwan, additional

Published
2018
Full Text
View/download PDF

48. Poor Prognosis of Lower Inner Quadrant in Lymph Node–negative Breast Cancer Patients Who Received No Chemotherapy: A Study Based on Nationwide Korean Breast Cancer Registry Database

Author

Hwang, Ki-Tae, primary, Kim, Jongjin, additional, Kim, Eun-Kyu, additional, Jung, Sung Hoo, additional, Sohn, Guiyun, additional, Kim, Seung Il, additional, Jeong, Joon, additional, Lee, Hyouk Jin, additional, Park, Jin Hyun, additional, Oh, Sohee, additional, Ahn, Sei Hyun, additional, Noh, Dong-Young, additional, Nam, Seok Jin, additional, Lee, Eun Sook, additional, Park, Byeong-Woo, additional, Noh, Woo Chul, additional, Yoon, Jung Han, additional, Lee, Soo Jung, additional, Lee, Eun Kyu, additional, Han, Sehwan, additional, Park, Ho Yong, additional, Paik, Nam-Sun, additional, Bae, Young Tae, additional, Park, Heung Kyu, additional, Ko, Seung Sang, additional, Song, Byung Joo, additional, Suh, Young Jin, additional, Cho, Se Heon, additional, Kim, Sei Joong, additional, Oh, Se Jeong, additional, Ko, Byung Kyun, additional, Kim, Ku Sang, additional, Park, Chanheun, additional, Baek, Jong-Min, additional, Hwang, Ki-Tae, additional, Chang, Il-Sung, additional, Bae, Jeoung Won, additional, Kim, Jeong-Soo, additional, Kang, Sun Hee, additional, Gwak, Geumhee, additional, Lee, Jee Hyun, additional, Kim, Tae Hyun, additional, Chang, Myungchul, additional, Kim, Sung Yong, additional, Lee, Jung Sun, additional, Song, Jeong-Yoon, additional, Park, Hai Lin, additional, Min, Sun Young, additional, Yang, Jung-Hyun, additional, Park, Sung Hwan, additional, Park, Woo-Chan, additional, Kim, Lee Su, additional, Ryu, Dong Won, additional, Kim, Kweon Cheon, additional, Chung, Min Sung, additional, Park, Hee Boong, additional, Lim, Cheol Wan, additional, Choi, Un Jong, additional, Kwak, Beom Seok, additional, Park, Young Sam, additional, Shin, Hyuk Jai, additional, Choi, Young Jin, additional, Kim, Doyil, additional, Han, Airi, additional, Koh, Jong Hyun, additional, Choi, Sangyong, additional, Yoon, Daesung, additional, Choi, Soo Youn, additional, Chul, Shin Hee, additional, Kim, Jae Il, additional, Choi, Jae Hyuck, additional, Ryu, Jin Woo, additional, Ko, Chang Dae, additional, Lee, Il Kyun, additional, Lee, Dong Seok, additional, Choi, Seunghye, additional, Min, Youn Ki, additional, Jeon, Young San, additional, and Park, Eun-Hwa, additional

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results