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Patients with psychiatric disorders experience a reduced quality of life also due to the antipsychotic drugs assumed, that negatively affects their cognitive abilities. A healthy lifestyle, such as physical activity, can improve both functional abilities and mental health of patients with a dual diagnosis, psychiatric and cognitive. Despite this knowledge, these people are more sedentary than the general population, probably because of their apathy, core aspects of the illness. Animal Assisted Interventions (AAIs) seem to be a valid tool to stimulate them to practice physical exercise thanks to the empathy generated by the relationship with the animal. This case study aims to evaluate the effect of 4 months AAIs on apathy and physical efficiency in 2 patients with dual diagnoses. Patient A and patient B, affected by psychiatric disorders and mild cognitive impairment, were recruited to perform an AAI, one with a dog and the other with a horse. At the end of the study data showed a decrease of apathy in both patients: −20,6% in patient A and −9.8% in patient B, as well as a reduction of psychiatric symptoms. Moreover, both patients improved the functional parameters evaluated through the Short Physical Battery Test (patient A = +33.3%; patient B = +28.6%). The preliminary results of this case report suggest that well-structured, individualized AAIs, with a horse or with a dog, could be considered as a useful adjunctive therapy to the usual treatment programs to improve both functional abilities and mental health in psychiatric patients. • Animal Assisted Interventions seem to counteract apathy in psychiatric patients with mild cognitive impairment. • Multidisciplinary teamwork can increase the involvement of psychiatric patients in rehabilitation programs. • Well-structured and individualized AAIs can improve the physical efficiency of psychiatric patients with dual diagnosis. [ABSTRACT FROM AUTHOR]

As athletes pursue excellence, training techniques continue to advance, making structured physical activity an essential tool for enhancing performance. To optimize athletic performance in modern competitive sports, the balance of physical performance and mental clarity is required. This study seeks to examine the effects of High-Intensity Interval Training (HIIT) on cognitive and physical skills in basketball and soccer players. A 3-week HIIT protocol was incorporated based on the Wingate technique. This study included 10 soccer players and 10 basketball players with an average age of 22.79 ± 1.90 years. Participants performed pre- and post-intervention assessments. Physical proficiency was assessed using 20 m sprint, change-of-direction (COD) and dribbling tests, while cognitive skills were assessed using motion object tracking (MOT), working memory, perceptual load (PL), and attention window (AW) tests. The HIIT intervention significantly improved cognitive performance in particular; noteworthy observations were a 15% improvement in motion object tracking test scores and a 16% increase in working memory test scores for basketball players. The attention window test scores showed a 32% increase, and perceptual load test scores were 31% decreased for soccer players post-intervention. There were significant improvements in physical skills; for example, sprint times were decreased by 6%, and change-of-direction and dribbling times were reduced by 8% and 7%, respectively, indicating improved agility, speed, and ball control abilities. In conclusion, both groups performed significantly better on cognitive and physical skill tests post-HIIT intervention. [ABSTRACT FROM AUTHOR]

Biological age, reflecting the cumulative damage in the body over a lifespan, is a dynamic measure more indicative of individual health than chronological age. Accelerated aging, when biological age surpasses chronological age, is implicated in poorer clinical outcomes, especially for breast cancer (BC) survivors undergoing treatments. This preliminary study investigates the impact of a 16-week online supervised physical activity (PA) intervention on biological age in post-surgery female BC patients. Telomere length was measured using qPCR, and the ELOVL2-based epigenetic clock was assessed via DNA methylation pyrosequencing of the ELOVL2 promoter region. Telomere length remained unchanged, but the ELOVL2 epigenetic clock indicated a significant decrease in biological age in the PA group, suggesting the potential of PA interventions to reverse accelerated aging processes in BC survivors. The exercise group showed improved cardiovascular fitness, highlighting PA's health impact. Finally, the reduction in biological age, as measured by the ELOVL2 epigenetic clock, was significantly associated with improvements in cardiovascular fitness and handgrip strength, supporting improved recovery. Epigenetic clocks can potentially assess health status and recovery progress in BC patients, identifying at-risk individuals in clinical practice. This study provides potential and valuable insights into how PA benefits BC survivors' health, supporting the immediate benefits of a 16-week exercise intervention in mitigating accelerated aging. The findings could suggest a holistic approach to improving the health and recovery of post-surgery BC patients. [ABSTRACT FROM AUTHOR]

Background: Chronic kidney disease (CKD) will become the fifth leading cause of death in the world by 2040. It is fundamental to prevent and treat this pathology to reduce its impact on national health costs. This trial's aim is to evaluate the effects induced by a combination of consumed functional foods (FFs) with adapted physical activity (APA) on the progression of CKD-related comorbidities. Methods: The study lasted 12 weeks. We divided 40 CKD patients into four groups: mixed (FF + APA), APA, FF and control group (usual care). The FFs were characterized by their total antioxidant capacity and antiradical activity. The APA was performed though an online training protocol, three times per week, 1 h each session. Results: At the end of the study, we observed, in the mixed group, a decrease in azotemia (p = 0.0272), diastolic blood pressure (p = 0.0169), and C-reactive protein (p = 0.0313), with increases in the FORD test (p = 0.0203) and fat free mass (p = 0.0258). The APA group showed a reduction in total cholesterol (p = 0.0039). Conclusions: The combination of FFs and APA can help counteract several CKD-related comorbidities, such as arterial hypertension, dyslipidemia and uremic sarcopenia, and improve the CKD patients' quality of life. [ABSTRACT FROM AUTHOR]

Background: Data in the literature have demonstrated the crucial role that vitamin D plays in the human organism, and recent studies also emphasize this essential role of vitamin D in athletes. Indeed, vitamin D acts on the skeletal muscles and plays a fundamental role in numerous physiological processes involved in immune function. Many factors such as sun exposure, skin tone, body mass index and chronic illness affect vitamin D levels. The aim of the study is to evaluate vitamin D levels in professional football players in Italy and investigate the variations in vitamin D values in footballers who train at different latitudes. Methods: The study performed is a retrospective observational study analyzing 25-OH vitamin D values in professional football players of the Italian First Division (Serie A). Two teams during the competitive season were selected: team A (latitude of 41° N in southern Italy) and team B (latitude of 45° N in northern Italy). Three time periods were identified and were classified as follows: the first quarter (May, June, July, and August), the second quarter (September, October, November, and December) and the third quarter (January, February, March, and April). The purpose of this was to study the average values of vitamin D during the year corresponding to different levels of sunlight exposure. Each athlete was subjected to at least one sampling during the three quarters of the competitive season. Results: Both vitamin D insufficiency (10.1%) and overt deficiency (1.93%) were found in Italian Serie A players. Insufficient vitamin D values are between 20 ng/mL and 29 ng/mL and overt deficiency values <20 ng/mL. At the same time, the data demonstrated a significant variation in vitamin D values depending on the period of the competitive season and the latitude of the cities of the two teams. In detail, there was no significant difference in the first quarter, while there was a significant increase in vitamin D values in team B in the second and third quarter, at p < 0.01 and p < 0.05, respectively. Conclusions: Latitude and seasons have a significant impact on vitamin D levels. Therefore, it is essential to measure vitamin D in professional football players, especially during the spring and winter months, so as to monitor changes in levels in relation to the season and latitude and evaluate any supplements. Further studies should be performed to evaluate the relationship between vitamin D deficiency and football players' athletic performance. [ABSTRACT FROM AUTHOR]

An observational retrospective study was conducted on 180 young competitive athletes. These children were revaluated after a mild/moderate SARS-CoV-2 infection through 3 different kind of protocol aimed at recognizing any cardiorespiratory complications due to the infection. The aim of the present study was to evaluate the results of "return to play" Italian protocols for readmission to competitive sport in the pediatric population. All of the subjects analyzed were readmitted to competitive sports after revaluation. None of the young athletes showed cardiorespiratory compromises at first and/or second level evaluation, confirming that in young population there is low risk of hospitalization and life-threatening complications after a mild/moderate infection. Italian simplified protocol for resuming sport have proved to be a valuable tool for health assessment both in adult and young athletes allowing them to resume their training in safety. [ABSTRACT FROM AUTHOR]

The goal of the following work was to identify the effects, positive or negative, of performing group-based physical activity (GBPA) in the workplace. In addition, the scope of the present research was to investigate some social and relational aspects of medical origin associated with the Happy Bones project. The sample consisted of 28 women between 47 and 67 years old, employees of the University of Rome "Foro Italico", in menopause, and inactive. The explorative nature of the investigation and the multidimensional aspect of the variables suggested the adoption of a qualitative method. Even though the survey did not fulfil the minimum standards of representativeness, interview analysis showed a positive trend in joining physical activity in the workplace, as shown by the good compliance of the participants with the proposed workplace training protocol. Personal motivation linked to the project itself or to the corresponding activity existed albeit to a secondary extent; the unifying element of the group existed regardless of the project and was due to the home institution, hence to the workplace. [ABSTRACT FROM AUTHOR]

Simple Summary: Operation Phalco is an experimental training protocol for breast cancer survivors implemented through a network of oncologists, sports medicine physicians and kinesiologists. The aim of this research is to evaluate the effects of an online adapted physical activity protocol with respect to a usual care on functional capacity, fatigue and quality of life of breast cancer patients. The protocol was structured by taking into account both cancer-related issues and the presence of comorbidities detected in the enrolled patients. For this reason, the patients recruited in the oncology centers of Rome and Verona were divided into three risk levels based on the risk stratification carried out by a sports medicine physician during a medical examination. The results evidenced the positive impact of a well-adapted physical activity on breast cancer patients' quality of life, suggesting that this program should be included as early as possible in the cancer patient's care process. The international literature emphasizes the importance of physical activity (PA) in the first steps after cancer surgery. The regular practice of physical exercise causes positive adaptations on several functional capacities, with positive consequences on patients' quality of life. This project aims to evaluate the effect of a post-operative training protocol, structured by taking into account both cancer-related issues and the presence of comorbidities, on functional capacities and quality of life of breast cancer survivors. Therefore, it was necessary to create a synergy between oncologists (referring physicians), sport medicine physicians (risk stratification and exercise prescription) and kinesiologists (trainers). Thirty-five post-surgery BC patients decided on a voluntary basis to attend an online Adapted PA (APA) protocol for 4 months, twice a week (APA Group) or Usual Care Group (UC Group). Functional capacity of the APA Group significantly increased, by 13.1% (p = 0.000), whereas perceived exertion decreased by 19.7% (p = 0.020). In the same group, the general health evaluated through the questionnaire EORTC-QLQ-C30 increased (p = 0.050). No differences were found in the UC Group. Operation Phalco, creating a network between oncologists, sports medicine physicians and kinesiologists, confirms the importance of structuring a post-operative path where APA should be included as early as possible in the cancer patient care. [ABSTRACT FROM AUTHOR]