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6 results on '"Pargai, Kamal"'

1. Sub-optimal neutralisation of omicron (B.1.1.529) variant by antibodies induced by vaccine alone or SARS-CoV-2 Infection plus vaccine (hybrid immunity) post 6-months

Author

Medigeshi, Guruprasad R, Batra, Gaurav, Murugesan, Deepika Rathna, Thiruvengadam, Ramachandran, Chattopadhyay, Souvick, Das, Bhabatosh, Gosain, Mudita, Ayushi, Singh, Janmejay, Anbalagan, Anantharaj, Shaman, Heena, Pargai, Kamal, Mehdi, Farha, Das, Soon Jyoti, Kahlon, Namrata, Singh, Savita, Kshetrapal, Pallavi, Wadhwa, Nitya, Pandey, Anil K, Bhatnagar, Shinjini, and Garg, Pramod Kumar

Published
2022
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2. A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 Delta variant

Author

Hingankar, Nitin, primary, Deshpande, Suprit, additional, Das, Payel, additional, Rizvi, Zaigham Abbas, additional, Wibmer, Constantinos Kurt, additional, Mashilo, Poppy, additional, Ansari, Mohammed Yousuf, additional, Burns, Alison, additional, Barman, Shawn, additional, Zhao, Fangzhu, additional, Mukherjee, Sohini, additional, Torres, Jonathan L., additional, Chattopadhyay, Souvick, additional, Mehdi, Farha, additional, Sutar, Jyoti, additional, Rathore, Deepak Kumar, additional, Pargai, Kamal, additional, Singh, Janmejay, additional, Sonar, Sudipta, additional, Jakhar, Kamini, additional, Dandotiya, Jyotsna, additional, Bhattacharyya, Sankar, additional, Mani, Shailendra, additional, Samal, Sweety, additional, Singh, Savita, additional, Kshetrapal, Pallavi, additional, Thiruvengadam, Ramachandran, additional, Batra, Gaurav, additional, Medigeshi, Guruprasad, additional, Ward, Andrew B., additional, Bhatnagar, Shinjini, additional, Awasthi, Amit, additional, Sok, Devin, additional, and Bhattacharya, Jayanta, additional

Published
2022
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3. BA.1 and BA.2 sub-lineages of Omicron variant have comparable replication kinetics and susceptibility to neutralization by antibodies

Author

Singh, Janmejay, primary, Panwar, Aleksha, additional, Anantharaj, Anbalagan, additional, Rani, Chitra, additional, Bhardwaj, Monika, additional, Kumar, Parveen, additional, Pargai, Kamal, additional, Chattopadhyay, Partha, additional, Devi, Priti, additional, Maurya, Ranjeet, additional, Mishra, Pallavi, additional, Pandey, Anil Kumar, additional, Pandey, Rajesh, additional, and Medigeshi, Guruprasad R., additional

Published
2022
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4. A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 delta variant

Author

Hingankar, Nitin, primary, Deshpande, Suprit, additional, Das, Payel, additional, Rizvi, Zaigham Abbas, additional, Burns, Alison, additional, Barman, Shawn, additional, Zhao, Fangzhu, additional, Ansari, Mohammed Yousuf, additional, Mukherjee, Sohini, additional, Torres, Jonathan L., additional, Chattopadhyay, Souvick, additional, Mehdi, Farha, additional, Sutar, Jyoti, additional, Rathore, Deepak Kumar, additional, Pargai, Kamal, additional, Singh, Janmejay, additional, Sonar, Sudipta, additional, Jakhar, Kamini, additional, Bhattacharyya, Sankar, additional, Mani, Shailendra, additional, Singh, Savita, additional, Dandotiya, Jyotsna, additional, Kshetrapal, Pallavi, additional, Thiruvengadam, Ramachandran, additional, Batra, Gaurav, additional, Medigeshi, Guruprasad R, additional, Ward, Andrew, additional, Bhatnagar, Shinjini, additional, Awasthi, Amit, additional, Sok, Devin, additional, and Bhattacharya, Jayanta, additional

Published
2021
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6. Development and Utilization of VHH Antibodies Derived from Camelus Dromedarius Against Foot-and-Mouth Disease Virus.

Author

Dash, Lipsa, Subramaniam, Saravanan, Khulape, Sagar A., Prusty, Bikash Ranjan, Pargai, Kamal, Narnaware, Shirish D., Patil, Niteen V., and Pattnaik, Bramhadev

Subjects
VIRUS inactivation, FOOT & mouth disease, CAMELS
Abstract

Foot-and-mouth disease (FMD) is an acute, highly contagious, and economically devastating viral disease of domestic and wildlife species. For effective implementation of FMD control program, there is an imperative need for developing a rapid, sensitive, and specific diagnostics which help in the identification of serotypes involved in the outbreaks. The humoral immune response of the Camelidae is unique since in these animals 75% of circulating antibodies are constituted by heavy-chain antibodies and 25% are conventional immunoglobulin with two identical heavy chains. In the present study, we developed and characterized FMD virus-specific single-domain heavy-chain antibodies (VHHs) against inactivated whole-virus antigens of FMDV serotypes O (INDR2/1975), A (IND40/2000), and Asia 1 (IND63/1972) vaccine strains. After six rounds of panning and enrichment, these VHHs were stably expressed in Escherichia coli cells. The VHHs directed against outer capsid proteins of FMD virus were successfully utilized as the capture antibody in liquid-phase blocking ELISA (LPBE) thus replacing rabbit coating antibodies. Our study demonstrated the utility of FMD virus-specific VHHs as potential candidates in FMD research and diagnostic application. [ABSTRACT FROM AUTHOR]

Published
2019
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