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A new report from the First Affiliated Hospital of Zhengzhou University in China explores the relationship between stent selection and the outcome of aneurysm treatment. The study, which included 302 patients, found that the occlusion rate of aneurysms decreased as the difference in diameters between the stent and parent artery increased. The authors suggest that a difference in diameters within the range of -0.25 to 0.5 mm may be appropriate in clinical practice. Other factors such as age, diabetes mellitus, aneurysm characteristics, and treatment methods were also found to be predictors of aneurysm persistence or occlusion. [Extracted from the article]

This document provides information about a clinical trial, NCT06600997, that is currently ongoing and aims to evaluate the effectiveness of flow diverters compared to conventional endovascular therapy for small unruptured cerebral aneurysms. The trial is a prospective, multicenter, randomized controlled clinical trial with open-label treatment and blinded endpoint assessment. The primary outcome measures include major recurrence, any stroke, or death at one year post-surgery, while secondary outcome measures include all-cause mortality, any stroke, major recurrence rate, transient ischemic attack occurrence rate, and various other factors. The trial is still recruiting participants and is expected to be completed by October 30, 2027. The trial is being conducted by Changhai Hospital, and data will be shared with researchers after the publication of the main results. [Extracted from the article]

This patent describes an occlusion device that has been developed to treat aneurysms, which are a common and potentially dangerous condition affecting a small percentage of the population. The device is designed to disrupt blood flow and block off larger and irregularly shaped aneurysms, with the aim of preventing hemorrhagic stroke and brain damage. The patent discusses different diagnostic methods and treatment techniques currently used, as well as the limitations of existing embolic materials and techniques. The occlusion device itself is made up of a compressible mesh structure with multiple axial mesh carriages, and it can be implanted into the aneurysm sac to create flow disruption and stasis. It can also be used for vessel occlusion and peripheral vascular embolization. The patent includes various embodiments and claims for the occlusion device. [Extracted from the article]

A new report from Nagoya University in Aichi, Japan discusses a technique for treating large or giant internal carotid artery aneurysms. The researchers combined n-butyl-2-cyanoacrylate and coils with flow control to achieve successful outcomes in all cases studied. The technique was effective in achieving complete aneurysmal occlusion and favorable clinical outcomes. This research provides valuable insights into the treatment of aneurysms and may be of interest to those studying cardiovascular diseases and conditions. [Extracted from the article]

The article discusses a study on the long-term effects of combined endovascular interventions for treating giant symptomatic intracranial aneurysms, conducted by the National Centre for Neurosurgery, Republic of Kazakhstan, published in the journal Clinical Trials Week on August 19, 2024. Topics include the methods of endovascular intervention, the impact on aneurysmal sac shrinkage, and volume reduction, as well as the study's design and follow-up procedures.

Stryker Ireland Technology Ltd has been issued a patent for an occlusion device that aims to treat and improve aneurysms, particularly neurovascular aneurysms. The device uses a minimal amount of fully-retrievable deployable material and addresses the disadvantages associated with current treatment methods. It consists of a solid marker and a low-profile resilient mesh body attached to the marker, designed to conform to the walls of the aneurysm. The device aims to minimize the need for anti-coagulation therapy and reduce the risk of clot emboli formation. The patent includes various embodiments and claims related to the device. [Extracted from the article]

A patent application has been filed for a method of embolization using transient materials. The invention aims to treat neovascularization, chronic inflammation, and vessels related to the production of ghrelin. The embolic material is fully biodegradable within a specific time frame, restoring normal blood flow and eliminating the need for further intervention. The method involves advancing a catheter through the vasculature to the target vessel and releasing the embolic material to block blood flow. The patent application also describes a medical system for performing the embolization procedure. [Extracted from the article]

A new report discusses research findings on aneurysms and the use of intraoperative indocyanine green-videoangiography (ICG-VA) during microsurgical treatment. The study, conducted at MacKay Memorial Hospital in Taipei, Taiwan, analyzed patient records from January 2012 to July 2018. The results showed that the use of ICG-VA significantly reduced the incidence of parent artery injury during surgery. However, the presence of aneurysm remnants was found to be more influenced by the expertise of the neurosurgeon rather than the use of ICG-VA. [Extracted from the article]

The document provides information about a clinical trial, NCT06303063, that is currently underway in China. The trial aims to evaluate the safety and effectiveness of the SINOMED IAS for the treatment of intracranial aneurysms. The primary endpoint of the trial is to assess the success of aneurysm occlusion at 6 months post-procedure. Other outcomes being measured include technical success, in-stent stenosis, stroke, mortality, adverse events, and device defects. The trial is ongoing and is expected to be completed by June 2025. [Extracted from the article]

A recent report from the Department of Neurosurgery discusses the use of a steerable microcatheter in the treatment of giant cerebral aneurysms with flow-diverting stents. The researchers describe a case in which a 73-year-old woman with a giant cavernous internal carotid artery aneurysm was successfully treated using this technique. The steerable microcatheter allowed for access to the distal parent artery, which was not possible with the standard technique. The researchers conclude that steerable microcatheters may be a viable option in cases where access to the distal parent artery is compromised. [Extracted from the article]

This article discusses a patent application for an occlusion device that aims to treat aneurysms, specifically neurovascular aneurysms. The inventor recognizes the need for improved devices that can effectively disrupt blood flow and treat larger and irregularly shaped aneurysms. The article provides information on the prevalence and risks associated with neurovascular aneurysms, as well as current diagnostic techniques and treatment methods. It also highlights the limitations of existing embolic materials and techniques. The patent application describes a mesh-based device that can be delivered and deployed using a microcatheter or other delivery systems, with various embodiments and manufacturing methods included. [Extracted from the article]

A study conducted at Cairo University evaluated the safety and efficacy of an endovascular deconstructive artery technique for treating dissecting posterior cerebral artery (PCA) aneurysms. The study analyzed the angiographic characteristics, technical data, and clinical outcomes of nine patients with dissecting PCA aneurysms treated between January 2019 and December 2022. The results showed that endovascular parent artery occlusion was an effective and safe treatment approach for PCA aneurysms, even without an occlusion test. However, the risk of perforator infarction should be considered in cases of P1 occlusion. [Extracted from the article]

A recent study conducted at Nara City Hospital in Japan focused on traumatic intracranial aneurysms (TICAs), which are rare and have a high mortality rate. The study presented a case of an 87-year-old male patient who experienced head trauma and was diagnosed with an enlarged acute subdural hematoma (ASDH) due to a ruptured TICA. The patient underwent endovascular intervention with parent artery occlusion (PAO) using n-butyl-2-cyanoacrylate (NBCA), resulting in the disappearance of the pseudoaneurysm. This is the first report of a TICA arising from the P3 segment that was treated with PAO using NBCA. Researchers emphasize the importance of considering TICAs when an enlarged hematoma caused by head injury is detected. [Extracted from the article]

A recent report from Zhejiang Chinese Medical University discusses the use of pipeline embolization devices (PED) as a new treatment for intracranial aneurysms, particularly irregular and giant aneurysms. The report presents a case study of a 48-year-old female patient with a saccular aneurysm in the right internal carotid artery. The patient underwent flow diverter stent and coil embolization, as well as dual antiplatelet therapy, and experienced improvement in neurological symptoms without complications. The researchers conclude that the combination of flow diverter stents and coil embolization is clinically significant for treating large saccular aneurysms and may serve as a reference for the treatment of aneurysmal parent artery. [Extracted from the article]

A patent has been issued for an occlusion device designed to treat neurovascular aneurysms. These aneurysms affect a small percentage of the population and can have serious complications. The current methods of treatment have limitations and risks. The new occlusion device aims to effectively treat larger and irregularly shaped aneurysms while minimizing complications. The device consists of a mesh structure that can be expanded to disrupt blood flow and promote healing. It can be delivered using a microcatheter or other delivery systems. The patent also includes claims for the device and a kit for aneurysm treatment. [Extracted from the article]

A patent application has been published for an invention by Daniel Ezra Walzman that aims to treat aneurysms and fistulas in the brain and other complex blood vessels. The device allows for precise positioning and orientation, with the ability to control blood flow as needed. It addresses the limitations of current technologies and offers a solution for effectively treating these conditions. The invention includes a system with specialized catheters and markers to accurately position stents and enable branch stenting. The goal is to optimize the insertion of stents into intricate anatomies and improve patient outcomes. [Extracted from the article]

An aneurysm occlusion system, comprising the aneurysm occlusion device according to claim 1 and a catheter, wherein the expandable mesh structure is compressed in the catheter and, after being released from the catheter, can recover the expanded configuration in which the expandable mesh structure forms the spiral shape. The aneurysm occlusion device according to claim 4, wherein the second section of the guide structure that extends out of the expandable mesh structure from the distal end thereof has a spiral shape when in the expanded configuration; or wherein the second section of the guide structure that extends out of the expandable mesh structure from the distal end thereof has a three-dimensional spiral shape. A therapeutic apparatus for aneurysm occlusion, comprising the aneurysm occlusion device according to claim 1 and a push pod connected to the proximal end of the expandable mesh structure in the aneurysm occlusion device. The aneurysm occlusion device according to claim 1, wherein both the proximal and distal ends of the expandable mesh structure are fixedly connected to the guide structure, and an axial length of a first section of the guide structure that is disposed in the inner cavity of the expandable mesh structure in the expanded configuration is not smaller than an axial length of the expandable mesh structure in the collapsed configuration. [Extracted from the article]

Aneurysm Occlusion Device, Therapeutic Apparatus For Aneurysm Occlusion And Aneurysm Occlusion System. An aneurysm occlusion system, comprising the aneurysm occlusion device according to claim 1 and a catheter, wherein the expandable structure is compressed in the catheter and, after being released from the catheter, recovers the expanded configuration in which the expandable structure forms the spiral shape. However, when released into an aneurysm, it will be stressed by walls of the aneurysm and assume a tulip-like shape, which allows it to be stabilized in a lower part of the aneurysm while covering the aneurysm neck to provide an effect of hemodynamic remodeling. [Extracted from the article]

An aneurysm occlusion system, comprising the aneurysm occlusion device of claim 1 and a catheter, wherein the expandable mesh structure is configured to be compressed within the catheter and to recover the expanded configuration with the spiral shape after being released from the catheter. Since the planar spiral structure will encounter reduced friction within the aneurysm, the expandable mesh structure can more easily recover and maintain a predetermined shape in the aneurysm, which is suitable for occlusion of the aneurysm neck. However, when released into an aneurysm, it will be stressed by walls of the aneurysm and comprises a tulip-like shape, which allows it to be stabilized in a lower part of the aneurysm while covering the aneurysm neck to provide an effect of hemodynamic remodeling. A therapeutic apparatus for aneurysm occlusion, comprising the aneurysm occlusion device of claim 1 and a push pod, wherein the push pod is coupled to a proximal end of the expandable mesh structure in the aneurysm occlusion device. [Extracted from the article]

Acrylates, Aneurysm, Angiology, Cardiovascular Diseases and Conditions, Cyanoacrylates, Dissecting Aneurysm, Embolization, Health and Medicine, Hemorrhage, Nitriles, Parent Artery, Posterior Inferior Cerebellar Artery Keywords: Acrylates; Aneurysm; Angiology; Cardiovascular Diseases and Conditions; Cyanoacrylates; Dissecting Aneurysm; Embolization; Health and Medicine; Hemorrhage; Nitriles; Parent Artery; Posterior Inferior Cerebellar Artery EN Acrylates Aneurysm Angiology Cardiovascular Diseases and Conditions Cyanoacrylates Dissecting Aneurysm Embolization Health and Medicine Hemorrhage Nitriles Parent Artery Posterior Inferior Cerebellar Artery 416 416 1 10/09/23 20231012 NES 231012 2023 OCT 9 (NewsRx) -- By a News Reporter-Staff News Editor at Hematology Week -- A new study on dissecting aneurysm is now available. [Extracted from the article]