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A clinical correspondence article titled "Reticular and confluent intertriginous papules in a woman" describes the case of a woman in her sixties who presented with mildly pruritic skin lesions on the inter- and inframammary folds. The woman had no relevant medical history, and a skin biopsy confirmed a diagnosis of granular parakeratosis (GP). GP is a rare, benign skin condition characterized by erythematous to brown hyperkeratotic papules and plaques that primarily affect intertriginous sites. Treatment with a daily application of calcipotriol/betamethasone cream resulted in complete resolution of the lesions after 8 weeks. [Extracted from the article]

Among the less common variants of primary cutaneous amyloidosis are both the poikylodermic and the familial types. The case of two sisters of thirteen and seventeen years old with extensive asymptomatic lesions with a poikylodermic aspect is reported. The girls' father was also affected and a paternal aunt had consulted at our department some years previously for similar lesions. Thus a new case of familial cutaneous amyloidosis with an autosomal dominant hereditary pattern is described. The possible relationship between multiple endocrine neoplasia type 2A (MEN-2A) and familial cutaneous amyloidosis is discussed.